Establishment and characterization of a novel chordoma cell line: CH22

Journal of Orthopaedic Research

Volumn 30, Issue 10, 2012, Pages 1666-1673

  Liu, Xianzhe ^a,b   Nielsen, Gunnlager Petur ^a   Rosenberg, Andrew E ^a   Waterman, Peter R ^a   Yang, Wen ^a,b   Choy, Edwin ^a   Sassi, Slim ^a   Yang, Shuhua ^b   Harmon, David C ^a   Yang, Cao ^b   Schwab, Joseph H ^a   Kobayashi, Eisuke ^a   Mankin, Henry J ^a   Xavier, Ramnik ^a   Weissleder, Ralph ^a   Duan, Zhenfeng ^a   Hornicek, Francis J ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

3D culture; chemotherapy; chordoma; tumorigenicity; xenograft

Indexed keywords

CISPLATIN; CYTOKERATIN; DOXORUBICIN; GLYCOGEN; METHOTREXATE; PACLITAXEL; PROTEIN S 100; VIMENTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CHEMOTHERAPY; CARCINOGENESIS; CELL CULTURE; CELL VACUOLE; CHORDOMA; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DRUG SENSITIVITY; ELECTRON MICROSCOPY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IC 50; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OSTEOSARCOMA CELL; PRIORITY JOURNAL; TONOFILAMENT; WESTERN BLOTTING;

ANIMALS; BIOLOGICAL MARKERS; BONE NEOPLASMS; CELL CULTURE TECHNIQUES; CELL LINE; CHORDOMA; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; MICE; MICE, NUDE; MICE, SCID; MIDDLE AGED; NEOPLASMS, EXPERIMENTAL; SACRUM;

EID: 84865505198     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.22113     Document Type: Article

References (23)

1. Salisbury JR., 1993. The pathology of the human notochord. J Pathol 171: 253-255. (Pubitemid 24022985)
2. Ho KL., 1985. Ecchordosis physaliphora and chordoma: a comparative ultrastructural study. Clin Neuropathol 4: 77-86. (Pubitemid 15117449)
3. Jemal A, Siegel R, Ward E, et al. 2007. Cancer statistics, 2007. CA Cancer J Clin 57: 43-66. (Pubitemid 46148091)
4. Nikoghosyan AV, Karapanagiotou-Schenkel I, Munter MW, et al. 2010. Randomised trial of proton vs. carbon ion radiation therapy in patients with chordoma of the skull base, clinical phase III study HIT-1-Study. BMC Cancer 10: 607.
5. Higinbotham NL, Phillips RF, Farr HW, et al. 1967. Chordoma. Thirty-five-year study at Memorial Hospital. Cancer 20: 1841-1850.
6. Chambers PW, Schwinn CP., 1979. Chordoma. A clinicopathologic study of metastasis. Am J Clin Pathol 72: 765-776. (Pubitemid 10158892)
7. Catton C, O'Sullivan B, Bell R, et al. 1996. Chordoma: long-term follow-up after radical photon irradiation. Radiother Oncol 41: 67-72.
8. Casali PG, Stacchiotti S, Sangalli C, et al. 2007. Chordoma. Curr Opin Oncol 19: 367-370. (Pubitemid 46883527)
9. Chugh R, Tawbi H, Lucas DR, et al. 2007. Chordoma: the nonsarcoma primary bone tumor. Oncologist 12: 1344-1350. (Pubitemid 350232608)
10. Pena CE, Horvat BL, Fisher ER., 1970. The ultrastructure of chordoma. Am J Clin Pathol 53: 544-551.
11. Scheil S, Bruderlein S, Liehr T, et al. 2001. Genome-wide analysis of sixteen chordomas by comparative genomic hybridization and cytogenetics of the first human chordoma cell line, U-CH1. Genes Chromosomes Cancer 32: 203-211. (Pubitemid 32953974)
12. Yang C, Hornicek FJ, Wood KB, et al. 2010. Characterization and analysis of human chordoma cell lines. Spine (PhilaPa 1976) 35: 1257-1264.
13. Hsu W, Mohyeldin A, Shah SR, et al. 2011. Generation of chordoma cell line JHC7 and the identification of Brachyury as a novel molecular target. J Neurosurg 115: 760-769.
14. Ostroumov E, Hunter CJ., 2007. The role of extracellular factors in human metastatic chordoma cell growth in vitro. Spine (PhilaPa 1976) 32: 2957-2964. (Pubitemid 350307277)
15. DeComas AM, Penfornis P, Harris MR, et al. 2010. Derivation and characterization of an extra-axial chordoma cell line (EACH-1) from a scapular tumor. J Bone Joint Surg Am 92: 1231-1240.
16. Rinner B, Froehlich EV, Buerger K, et al. 2011. Establishment and detailed functional and molecular genetic characterisation of a novel sacral chordoma cell line, MUG-Chor1. Int J Oncol 40: 443-451.
17. Presneau N, Shalaby A, Ye H, et al. 2010. Role of the transcription factor T (brachyury) in the pathogenesis of sporadic chordoma: a genetic and functional-based study. J Pathol 223: 327-335.
18. Chifenti B, Morelli M, Zavaglia M, et al. 2009. Establishment and characterization of 4 new human pancreatic cancer cell lines: evidences of different tumor phenotypes. Pancreas 38: 184-196.
19. Ku JL, Shin YK, Kim DW, et al. 2010. Establishment and characterization of 13 human colorectal carcinoma cell lines: mutations of genes and expressions of drug-sensitivity genes and cancer stem cell markers. Carcinogenesis 31: 1003-1009.
20. Duan Z, Choy E, Harmon D, et al. 2009. Insulin-like growth factor-I receptor tyrosine kinase inhibitor cyclolignan picropodophyllin inhibits proliferation and induces apoptosis in multidrug resistant osteosarcoma cell lines. Mol Cancer Ther 8: 2122-2130.
21. Ulukaya E, Colakogullari M, Wood EJ., 2004. Interference by anti-cancer chemotherapeutic agents in the MTT-tumor chemosensitivity assay. Chemotherapy 50: 43-50. (Pubitemid 38490200)
22. Vujovic S, Henderson S, Presneau N, et al. 2006. Brachyury, a crucial regulator of notochordal development, is a novel biomarker for chordomas. J Pathol 209: 157-165. (Pubitemid 43805410)
23. Presneau N, Shalaby A, Idowu B, et al. 2009. Potential therapeutic targets for chordoma: PI3K/AKT/TSC1/TSC2/mTOR pathway. Br J Cancer 100: 1406-1414.