메뉴 건너뛰기




Volumn 13, Issue , 2013, Pages

Odontogenic ameloblast-associated protein (ODAM) inhibits growth and migration of human melanoma cells and elicits PTEN elevation and inactivation of PI3K/AKT signaling

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; ODONTOGENIC AMELOBLAST ASSOCIATED PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; TUMOR MARKER; UNCLASSIFIED DRUG;

EID: 84877021352     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-13-227     Document Type: Article
Times cited : (13)

References (72)
  • 1
    • 57349094378 scopus 로고    scopus 로고
    • Recent trends in incidence of cutaneous melanoma among US Caucasian young adults
    • 10.1038/jid.2008.159, 2741632, 18615112
    • Purdue MP, Freeman LE, Anderson WF, Tucker MA. Recent trends in incidence of cutaneous melanoma among US Caucasian young adults. J Invest Dermatol 2008, 128(12):2905-2908. 10.1038/jid.2008.159, 2741632, 18615112.
    • (2008) J Invest Dermatol , vol.128 , Issue.12 , pp. 2905-2908
    • Purdue, M.P.1    Freeman, L.E.2    Anderson, W.F.3    Tucker, M.A.4
  • 2
    • 0034036053 scopus 로고    scopus 로고
    • Incidence of sentinel node metastasis in patients with thin primary melanoma (< or = 1 mm) with vertical growth phase
    • 10.1007/s10434-000-0262-z, 10819365
    • Bedrosian I, Faries MB, Guerry DT, Elenitsas R, Schuchter L, Mick R, Spitz FR, Bucky LP, Alavi A, Elder DE. Incidence of sentinel node metastasis in patients with thin primary melanoma (< or = 1 mm) with vertical growth phase. Ann Surg Oncol 2000, 7(4):262-267. 10.1007/s10434-000-0262-z, 10819365.
    • (2000) Ann Surg Oncol , vol.7 , Issue.4 , pp. 262-267
    • Bedrosian, I.1    Faries, M.B.2    Guerry, D.T.3    Elenitsas, R.4    Schuchter, L.5    Mick, R.6    Spitz, F.R.7    Bucky, L.P.8    Alavi, A.9    Elder, D.E.10
  • 3
    • 70349684479 scopus 로고    scopus 로고
    • Melanoma biomarkers: current status and utility in diagnosis, prognosis, and response to therapy
    • 10.1007/BF03256334, 19791833
    • Haass NK, Smalley KS. Melanoma biomarkers: current status and utility in diagnosis, prognosis, and response to therapy. Mol Diagn Ther 2009, 13(5):283-296. 10.1007/BF03256334, 19791833.
    • (2009) Mol Diagn Ther , vol.13 , Issue.5 , pp. 283-296
    • Haass, N.K.1    Smalley, K.S.2
  • 4
    • 73949120017 scopus 로고    scopus 로고
    • Melanoma biomarkers: current status and vision for the future
    • 10.1038/ncponc1296, 19107110
    • Larson AR, Konat E, Alani RM. Melanoma biomarkers: current status and vision for the future. Nat Clin Pract Oncol 2009, 6(2):105-117. 10.1038/ncponc1296, 19107110.
    • (2009) Nat Clin Pract Oncol , vol.6 , Issue.2 , pp. 105-117
    • Larson, A.R.1    Konat, E.2    Alani, R.M.3
  • 5
    • 84866328917 scopus 로고    scopus 로고
    • Tumor profiling using protein biomarker panels in malignant melanoma: application of tissue microarrays and beyond
    • 10.1586/epr.12.5, 22967078
    • Joyce CW, Murphy IG, Rafferty M, Ryan D, McDermott EW, Gallagher WM. Tumor profiling using protein biomarker panels in malignant melanoma: application of tissue microarrays and beyond. Expert Rev Proteomics 2012, 9(4):415-423. 10.1586/epr.12.5, 22967078.
    • (2012) Expert Rev Proteomics , vol.9 , Issue.4 , pp. 415-423
    • Joyce, C.W.1    Murphy, I.G.2    Rafferty, M.3    Ryan, D.4    McDermott, E.W.5    Gallagher, W.M.6
  • 7
    • 1442274619 scopus 로고    scopus 로고
    • Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1 inactivation in melanoma
    • 10.1046/j.0022-202X.2004.22243.x, 2586668, 15009714
    • Tsao H, Goel V, Wu H, Yang G, Haluska FG. Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1 inactivation in melanoma. J Invest Dermatol 2004, 122(2):337-341. 10.1046/j.0022-202X.2004.22243.x, 2586668, 15009714.
    • (2004) J Invest Dermatol , vol.122 , Issue.2 , pp. 337-341
    • Tsao, H.1    Goel, V.2    Wu, H.3    Yang, G.4    Haluska, F.G.5
  • 11
    • 44649092289 scopus 로고    scopus 로고
    • Odontogenic ameloblast-associated protein nature of the amyloid found in calcifying epithelial odontogenic tumors and unerupted tooth follicles
    • 10.1080/13506120802005965, 18484335
    • Murphy CL, Kestler DP, Foster JS, Wang S, Macy SD, Kennel SJ, Carlson ER, Hudson J, Weiss DT, Solomon A. Odontogenic ameloblast-associated protein nature of the amyloid found in calcifying epithelial odontogenic tumors and unerupted tooth follicles. Amyloid 2008, 15(2):89-95. 10.1080/13506120802005965, 18484335.
    • (2008) Amyloid , vol.15 , Issue.2 , pp. 89-95
    • Murphy, C.L.1    Kestler, D.P.2    Foster, J.S.3    Wang, S.4    Macy, S.D.5    Kennel, S.J.6    Carlson, E.R.7    Hudson, J.8    Weiss, D.T.9    Solomon, A.10
  • 12
    • 34247505174 scopus 로고    scopus 로고
    • The amyloid protein APin is highly expressed during enamel mineralization and maturation in rat incisors
    • 10.1111/j.1600-0722.2007.00435.x, 17451507
    • Park JC, Park JT, Son HH, Kim HJ, Jeong MJ, Lee CS, Dey R, Cho MI. The amyloid protein APin is highly expressed during enamel mineralization and maturation in rat incisors. Eur J Oral Sci 2007, 115(2):153-160. 10.1111/j.1600-0722.2007.00435.x, 17451507.
    • (2007) Eur J Oral Sci , vol.115 , Issue.2 , pp. 153-160
    • Park, J.C.1    Park, J.T.2    Son, H.H.3    Kim, H.J.4    Jeong, M.J.5    Lee, C.S.6    Dey, R.7    Cho, M.I.8
  • 13
    • 39049165852 scopus 로고    scopus 로고
    • Characterization of Apin, a secreted protein highly expressed in tooth-associated epithelia
    • 10.1002/jcb.21465, 17647262
    • Moffatt P, Smith CE, St-Arnaud R, Nanci A. Characterization of Apin, a secreted protein highly expressed in tooth-associated epithelia. J Cell Biochem 2008, 103(3):941-956. 10.1002/jcb.21465, 17647262.
    • (2008) J Cell Biochem , vol.103 , Issue.3 , pp. 941-956
    • Moffatt, P.1    Smith, C.E.2    St-Arnaud, R.3    Nanci, A.4
  • 14
    • 33646155334 scopus 로고    scopus 로고
    • Systematic search for gastric cancer-specific genes based on SAGE data: melanoma inhibitory activity and matrix metalloproteinase-10 are novel prognostic factors in patients with gastric cancer
    • 10.1038/sj.onc.1209279, 16331256
    • Aung PP, Oue N, Mitani Y, Nakayama H, Yoshida K, Noguchi T, Bosserhoff AK, Yasui W. Systematic search for gastric cancer-specific genes based on SAGE data: melanoma inhibitory activity and matrix metalloproteinase-10 are novel prognostic factors in patients with gastric cancer. Oncogene 2006, 25(17):2546-2557. 10.1038/sj.onc.1209279, 16331256.
    • (2006) Oncogene , vol.25 , Issue.17 , pp. 2546-2557
    • Aung, P.P.1    Oue, N.2    Mitani, Y.3    Nakayama, H.4    Yoshida, K.5    Noguchi, T.6    Bosserhoff, A.K.7    Yasui, W.8
  • 15
    • 44649112969 scopus 로고    scopus 로고
    • Expression of odontogenic ameloblast-associated protein (ODAM) in dental and other epithelial neoplasms
    • 2323332, 18472969
    • Kestler DP, Foster JS, Macy SD, Murphy CL, Weiss DT, Solomon A. Expression of odontogenic ameloblast-associated protein (ODAM) in dental and other epithelial neoplasms. Mol Med 2008, 14(5-6):318-326. 2323332, 18472969.
    • (2008) Mol Med , vol.14 , Issue.5-6 , pp. 318-326
    • Kestler, D.P.1    Foster, J.S.2    Macy, S.D.3    Murphy, C.L.4    Weiss, D.T.5    Solomon, A.6
  • 16
    • 84862813619 scopus 로고    scopus 로고
    • Expression pattern, subcellular localization, and functional implications of ODAM in ameloblasts, odontoblasts, osteoblasts, and various cancer cells
    • Lee HK, Park SJ, Oh HJ, Kim JW, Bae HS, Park JC. Expression pattern, subcellular localization, and functional implications of ODAM in ameloblasts, odontoblasts, osteoblasts, and various cancer cells. Gene Expr Patterns 2012, 12(3-4):102-108.
    • (2012) Gene Expr Patterns , vol.12 , Issue.3-4 , pp. 102-108
    • Lee, H.K.1    Park, S.J.2    Oh, H.J.3    Kim, J.W.4    Bae, H.S.5    Park, J.C.6
  • 17
    • 70349782457 scopus 로고    scopus 로고
    • Odontogenic ameloblast associated protein as a novel biomarker for human breast cancer
    • discussion 775
    • Siddiqui S, Bruker CT, Kestler DP, Foster JS, Gray KD, Solomon A, Bell JL. Odontogenic ameloblast associated protein as a novel biomarker for human breast cancer. Am Surg 2009, 75(9):769-775. discussion 775.
    • (2009) Am Surg , vol.75 , Issue.9 , pp. 769-775
    • Siddiqui, S.1    Bruker, C.T.2    Kestler, D.P.3    Foster, J.S.4    Gray, K.D.5    Solomon, A.6    Bell, J.L.7
  • 21
    • 0035139077 scopus 로고    scopus 로고
    • Multifaceted regulation of cell cycle progression by estrogen: regulation of Cdk inhibitors and Cdc25A independent of cyclin D1-Cdk4 function
    • 10.1128/MCB.21.3.794-810.2001, 86671, 11154267
    • Foster JS, Henley DC, Bukovsky A, Seth P, Wimalasena J. Multifaceted regulation of cell cycle progression by estrogen: regulation of Cdk inhibitors and Cdc25A independent of cyclin D1-Cdk4 function. Mol Cell Biol 2001, 21(3):794-810. 10.1128/MCB.21.3.794-810.2001, 86671, 11154267.
    • (2001) Mol Cell Biol , vol.21 , Issue.3 , pp. 794-810
    • Foster, J.S.1    Henley, D.C.2    Bukovsky, A.3    Seth, P.4    Wimalasena, J.5
  • 22
    • 0142135033 scopus 로고    scopus 로고
    • Estrogens down-regulate p27Kip1 in breast cancer cells through Skp2 and through nuclear export mediated by the ERK pathway
    • 10.1074/jbc.M302830200, 12904306
    • Foster JS, Fernando RI, Ishida N, Nakayama KI, Wimalasena J. Estrogens down-regulate p27Kip1 in breast cancer cells through Skp2 and through nuclear export mediated by the ERK pathway. J Biol Chem 2003, 278(42):41355-41366. 10.1074/jbc.M302830200, 12904306.
    • (2003) J Biol Chem , vol.278 , Issue.42 , pp. 41355-41366
    • Foster, J.S.1    Fernando, R.I.2    Ishida, N.3    Nakayama, K.I.4    Wimalasena, J.5
  • 23
    • 77952902430 scopus 로고    scopus 로고
    • Mechanisms of motility in metastasizing cells
    • 10.1158/1541-7786.MCR-10-0139, 20460404
    • Yilmaz M, Christofori G. Mechanisms of motility in metastasizing cells. Mol Cancer Res 2010, 8(5):629-642. 10.1158/1541-7786.MCR-10-0139, 20460404.
    • (2010) Mol Cancer Res , vol.8 , Issue.5 , pp. 629-642
    • Yilmaz, M.1    Christofori, G.2
  • 24
    • 0035823542 scopus 로고    scopus 로고
    • Regulation of Raf by Akt controls growth and differentiation in vascular smooth muscle cells
    • 10.1074/jbc.M105322200, 11443134
    • Reusch HP, Zimmermann S, Schaefer M, Paul M, Moelling K. Regulation of Raf by Akt controls growth and differentiation in vascular smooth muscle cells. J Biol Chem 2001, 276(36):33630-33637. 10.1074/jbc.M105322200, 11443134.
    • (2001) J Biol Chem , vol.276 , Issue.36 , pp. 33630-33637
    • Reusch, H.P.1    Zimmermann, S.2    Schaefer, M.3    Paul, M.4    Moelling, K.5
  • 25
    • 33746257209 scopus 로고    scopus 로고
    • The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
    • 10.1038/nrg1879, 16847462
    • Engelman JA, Luo J, Cantley LC. The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism. Nat Rev Genet 2006, 7(8):606-619. 10.1038/nrg1879, 16847462.
    • (2006) Nat Rev Genet , vol.7 , Issue.8 , pp. 606-619
    • Engelman, J.A.1    Luo, J.2    Cantley, L.C.3
  • 26
    • 13844312400 scopus 로고    scopus 로고
    • Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
    • 10.1126/science.1106148, 15718470
    • Sarbassov DD, Guertin DA, Ali SM, Sabatini DM. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 2005, 307(5712):1098-1101. 10.1126/science.1106148, 15718470.
    • (2005) Science , vol.307 , Issue.5712 , pp. 1098-1101
    • Sarbassov, D.D.1    Guertin, D.A.2    Ali, S.M.3    Sabatini, D.M.4
  • 27
    • 0032577699 scopus 로고    scopus 로고
    • The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
    • 10.1074/jbc.273.22.13375, 9593664
    • Maehama T, Dixon JE. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 1998, 273(22):13375-13378. 10.1074/jbc.273.22.13375, 9593664.
    • (1998) J Biol Chem , vol.273 , Issue.22 , pp. 13375-13378
    • Maehama, T.1    Dixon, J.E.2
  • 29
    • 13044305289 scopus 로고    scopus 로고
    • PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway
    • 10.1073/pnas.96.11.6199, 26859, 10339565
    • Sun H, Lesche R, Li DM, Liliental J, Zhang H, Gao J, Gavrilova N, Mueller B, Liu X, Wu H. PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway. Proc Natl Acad Sci USA 1999, 96(11):6199-6204. 10.1073/pnas.96.11.6199, 26859, 10339565.
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.11 , pp. 6199-6204
    • Sun, H.1    Lesche, R.2    Li, D.M.3    Liliental, J.4    Zhang, H.5    Gao, J.6    Gavrilova, N.7    Mueller, B.8    Liu, X.9    Wu, H.10
  • 30
    • 0033604468 scopus 로고    scopus 로고
    • The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells
    • 10.1038/sj.onc.1203183, 10597304
    • Lu Y, Lin YZ, LaPushin R, Cuevas B, Fang X, Yu SX, Davies MA, Khan H, Furui T, Mao M. The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells. Oncogene 1999, 18(50):7034-7045. 10.1038/sj.onc.1203183, 10597304.
    • (1999) Oncogene , vol.18 , Issue.50 , pp. 7034-7045
    • Lu, Y.1    Lin, Y.Z.2    LaPushin, R.3    Cuevas, B.4    Fang, X.5    Yu, S.X.6    Davies, M.A.7    Khan, H.8    Furui, T.9    Mao, M.10
  • 31
    • 77958554378 scopus 로고    scopus 로고
    • Disruption of periodontal integrity induces expression of apin by epithelial cell rests of Malassez
    • 10.1111/j.1600-0765.2010.01288.x, 20572917
    • Nishio C, Wazen R, Kuroda S, Moffatt P, Nanci A. Disruption of periodontal integrity induces expression of apin by epithelial cell rests of Malassez. J Periodontal Res 2010, 45(6):709-713. 10.1111/j.1600-0765.2010.01288.x, 20572917.
    • (2010) J Periodontal Res , vol.45 , Issue.6 , pp. 709-713
    • Nishio, C.1    Wazen, R.2    Kuroda, S.3    Moffatt, P.4    Nanci, A.5
  • 32
    • 79953066960 scopus 로고    scopus 로고
    • Expression pattern of odontogenic ameloblast-associated and amelotin during formation and regeneration of the junctional epithelium
    • Nishio C, Wazen R, Kuroda S, Moffatt P, Nanci A. Expression pattern of odontogenic ameloblast-associated and amelotin during formation and regeneration of the junctional epithelium. Eur Cell Mater 2010, 20:393-402.
    • (2010) Eur Cell Mater , vol.20 , pp. 393-402
    • Nishio, C.1    Wazen, R.2    Kuroda, S.3    Moffatt, P.4    Nanci, A.5
  • 33
    • 33646507037 scopus 로고    scopus 로고
    • Identification of secreted and membrane proteins in the rat incisor enamel organ using a signal-trap screening approach
    • discussion 164-135, 380-131
    • Moffatt P, Smith CE, Sooknanan R, St-Arnaud R, Nanci A. Identification of secreted and membrane proteins in the rat incisor enamel organ using a signal-trap screening approach. Eur J Oral Sci 2006, 114(Suppl 1):139-146. discussion 164-135, 380-131.
    • (2006) Eur J Oral Sci , vol.114 , Issue.SUPPL. 1 , pp. 139-146
    • Moffatt, P.1    Smith, C.E.2    Sooknanan, R.3    St-Arnaud, R.4    Nanci, A.5
  • 34
    • 78449306792 scopus 로고    scopus 로고
    • The odontogenic ameloblast-associated protein (ODAM) cooperates with RUNX2 and modulates enamel mineralization via regulation of MMP-20
    • 10.1002/jcb.22766, 20665536
    • Lee HK, Lee DS, Ryoo HM, Park JT, Park SJ, Bae HS, Cho MI, Park JC. The odontogenic ameloblast-associated protein (ODAM) cooperates with RUNX2 and modulates enamel mineralization via regulation of MMP-20. J Cell Biochem 2010, 111(3):755-767. 10.1002/jcb.22766, 20665536.
    • (2010) J Cell Biochem , vol.111 , Issue.3 , pp. 755-767
    • Lee, H.K.1    Lee, D.S.2    Ryoo, H.M.3    Park, J.T.4    Park, S.J.5    Bae, H.S.6    Cho, M.I.7    Park, J.C.8
  • 35
    • 0030936323 scopus 로고    scopus 로고
    • PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
    • 10.1126/science.275.5308.1943, 9072974
    • Li J, Yen C, Liaw D, Podsypanina K, Bose S, Wang SI, Puc J, Miliaresis C, Rodgers L, McCombie R. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 1997, 275(5308):1943-1947. 10.1126/science.275.5308.1943, 9072974.
    • (1997) Science , vol.275 , Issue.5308 , pp. 1943-1947
    • Li, J.1    Yen, C.2    Liaw, D.3    Podsypanina, K.4    Bose, S.5    Wang, S.I.6    Puc, J.7    Miliaresis, C.8    Rodgers, L.9    McCombie, R.10
  • 36
    • 17144436629 scopus 로고    scopus 로고
    • Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
    • 10.1038/ng0497-356, 9090379
    • Steck PA, Pershouse MA, Jasser SA, Yung WK, Lin H, Ligon AH, Langford LA, Baumgard ML, Hattier T, Davis T. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat Genet 1997, 15(4):356-362. 10.1038/ng0497-356, 9090379.
    • (1997) Nat Genet , vol.15 , Issue.4 , pp. 356-362
    • Steck, P.A.1    Pershouse, M.A.2    Jasser, S.A.3    Yung, W.K.4    Lin, H.5    Ligon, A.H.6    Langford, L.A.7    Baumgard, M.L.8    Hattier, T.9    Davis, T.10
  • 37
    • 13144249184 scopus 로고    scopus 로고
    • High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice
    • 10.1016/S0960-9822(07)00488-5, 9799734
    • Suzuki A, de la Pompa JL, Stambolic V, Elia AJ, Sasaki T, del Barco BI, Ho A, Wakeham A, Itie A, Khoo W. High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice. Curr Biol 1998, 8(21):1169-1178. 10.1016/S0960-9822(07)00488-5, 9799734.
    • (1998) Curr Biol , vol.8 , Issue.21 , pp. 1169-1178
    • Suzuki, A.1    de la Pompa, J.L.2    Stambolic, V.3    Elia, A.J.4    Sasaki, T.5    del Barco, B.I.6    Ho, A.7    Wakeham, A.8    Itie, A.9    Khoo, W.10
  • 39
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-Kinase AKT pathway in human cancer
    • 10.1038/nrc839, 12094235
    • Vivanco I, Sawyers CL. The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat Rev Cancer 2002, 2(7):489-501. 10.1038/nrc839, 12094235.
    • (2002) Nat Rev Cancer , vol.2 , Issue.7 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 40
    • 0033819340 scopus 로고    scopus 로고
    • Epigenetic PTEN silencing in malignant melanomas without PTEN mutation
    • 10.1016/S0002-9440(10)64627-5, 1850161, 11021816
    • Zhou XP, Gimm O, Hampel H, Niemann T, Walker MJ, Eng C. Epigenetic PTEN silencing in malignant melanomas without PTEN mutation. Am J Pathol 2000, 157(4):1123-1128. 10.1016/S0002-9440(10)64627-5, 1850161, 11021816.
    • (2000) Am J Pathol , vol.157 , Issue.4 , pp. 1123-1128
    • Zhou, X.P.1    Gimm, O.2    Hampel, H.3    Niemann, T.4    Walker, M.J.5    Eng, C.6
  • 41
    • 0037011674 scopus 로고    scopus 로고
    • PTEN/MMAC1 expression in melanoma resection specimens
    • 10.1038/sj.bjc.6600653, 2376294, 12454773
    • Deichmann M, Thome M, Benner A, Egner U, Hartschuh W, Naher H. PTEN/MMAC1 expression in melanoma resection specimens. Br J Cancer 2002, 87(12):1431-1436. 10.1038/sj.bjc.6600653, 2376294, 12454773.
    • (2002) Br J Cancer , vol.87 , Issue.12 , pp. 1431-1436
    • Deichmann, M.1    Thome, M.2    Benner, A.3    Egner, U.4    Hartschuh, W.5    Naher, H.6
  • 42
    • 0036568378 scopus 로고    scopus 로고
    • Nuclear PTEN expression and clinicopathologic features in a population-based series of primary cutaneous melanoma
    • 10.1002/ijc.10294, 11948493
    • Whiteman DC, Zhou XP, Cummings MC, Pavey S, Hayward NK, Eng C. Nuclear PTEN expression and clinicopathologic features in a population-based series of primary cutaneous melanoma. Int J Cancer 2002, 99(1):63-67. 10.1002/ijc.10294, 11948493.
    • (2002) Int J Cancer , vol.99 , Issue.1 , pp. 63-67
    • Whiteman, D.C.1    Zhou, X.P.2    Cummings, M.C.3    Pavey, S.4    Hayward, N.K.5    Eng, C.6
  • 43
    • 79953038262 scopus 로고    scopus 로고
    • PTEN loss in the continuum of common cancers, rare syndromes and mouse models
    • Hollander MC, Blumenthal GM, Dennis PA. PTEN loss in the continuum of common cancers, rare syndromes and mouse models. Nat Rev Cancer 2011, 11(4):289-301.
    • (2011) Nat Rev Cancer , vol.11 , Issue.4 , pp. 289-301
    • Hollander, M.C.1    Blumenthal, G.M.2    Dennis, P.A.3
  • 44
    • 66149141021 scopus 로고    scopus 로고
    • PTEN and the PI3-kinase pathway in cancer
    • 10.1146/annurev.pathol.4.110807.092311, 2710138, 18767981
    • Chalhoub N, Baker SJ. PTEN and the PI3-kinase pathway in cancer. Annu Rev Pathol 2009, 4:127-150. 10.1146/annurev.pathol.4.110807.092311, 2710138, 18767981.
    • (2009) Annu Rev Pathol , vol.4 , pp. 127-150
    • Chalhoub, N.1    Baker, S.J.2
  • 45
    • 84860217431 scopus 로고    scopus 로고
    • The functions and regulation of the PTEN tumour suppressor
    • Song MS, Salmena L, Pandolfi PP. The functions and regulation of the PTEN tumour suppressor. Nat Rev Mol Cell Biol 2012, 13(5):283-296.
    • (2012) Nat Rev Mol Cell Biol , vol.13 , Issue.5 , pp. 283-296
    • Song, M.S.1    Salmena, L.2    Pandolfi, P.P.3
  • 47
    • 80051680291 scopus 로고    scopus 로고
    • A continuum model for tumour suppression
    • 10.1038/nature10275, 3206311, 21833082
    • Berger AH, Knudson AG, Pandolfi PP. A continuum model for tumour suppression. Nature 2011, 476(7359):163-169. 10.1038/nature10275, 3206311, 21833082.
    • (2011) Nature , vol.476 , Issue.7359 , pp. 163-169
    • Berger, A.H.1    Knudson, A.G.2    Pandolfi, P.P.3
  • 50
    • 68949121012 scopus 로고    scopus 로고
    • X-linked inhibitor of apoptosis protein (XIAP) regulates PTEN ubiquitination, content, and compartmentalization
    • 10.1074/jbc.C109.009522, 2742810, 19473982
    • Van Themsche C, Leblanc V, Parent S, Asselin E. X-linked inhibitor of apoptosis protein (XIAP) regulates PTEN ubiquitination, content, and compartmentalization. J Biol Chem 2009, 284(31):20462-20466. 10.1074/jbc.C109.009522, 2742810, 19473982.
    • (2009) J Biol Chem , vol.284 , Issue.31 , pp. 20462-20466
    • Van Themsche, C.1    Leblanc, V.2    Parent, S.3    Asselin, E.4
  • 51
    • 63249130027 scopus 로고    scopus 로고
    • Rak functions as a tumor suppressor by regulating PTEN protein stability and function
    • 10.1016/j.ccr.2009.02.012, 2673492, 19345329
    • Yim EK, Peng G, Dai H, Hu R, Li K, Lu Y, Mills GB, Meric-Bernstam F, Hennessy BT, Craven RJ. Rak functions as a tumor suppressor by regulating PTEN protein stability and function. Cancer Cell 2009, 15(4):304-314. 10.1016/j.ccr.2009.02.012, 2673492, 19345329.
    • (2009) Cancer Cell , vol.15 , Issue.4 , pp. 304-314
    • Yim, E.K.1    Peng, G.2    Dai, H.3    Hu, R.4    Li, K.5    Lu, Y.6    Mills, G.B.7    Meric-Bernstam, F.8    Hennessy, B.T.9    Craven, R.J.10
  • 52
    • 78249236544 scopus 로고    scopus 로고
    • Recombinant human erythropoietin antagonizes trastuzumab treatment of breast cancer cells via Jak2-mediated Src activation and PTEN inactivation
    • 10.1016/j.ccr.2010.10.025, 3022383, 21075308
    • Liang K, Esteva FJ, Albarracin C, Stemke-Hale K, Lu Y, Bianchini G, Yang CY, Li Y, Li X, Chen CT. Recombinant human erythropoietin antagonizes trastuzumab treatment of breast cancer cells via Jak2-mediated Src activation and PTEN inactivation. Cancer Cell 2010, 18(5):423-435. 10.1016/j.ccr.2010.10.025, 3022383, 21075308.
    • (2010) Cancer Cell , vol.18 , Issue.5 , pp. 423-435
    • Liang, K.1    Esteva, F.J.2    Albarracin, C.3    Stemke-Hale, K.4    Lu, Y.5    Bianchini, G.6    Yang, C.Y.7    Li, Y.8    Li, X.9    Chen, C.T.10
  • 53
    • 27444445782 scopus 로고    scopus 로고
    • Cooperative phosphorylation of the tumor suppressor phosphatase and tensin homologue (PTEN) by casein kinases and glycogen synthase kinase 3beta
    • 10.1074/jbc.M503045200, 16107342
    • Al-Khouri AM, Ma Y, Togo SH, Williams S, Mustelin T. Cooperative phosphorylation of the tumor suppressor phosphatase and tensin homologue (PTEN) by casein kinases and glycogen synthase kinase 3beta. J Biol Chem 2005, 280(42):35195-35202. 10.1074/jbc.M503045200, 16107342.
    • (2005) J Biol Chem , vol.280 , Issue.42 , pp. 35195-35202
    • Al-Khouri, A.M.1    Ma, Y.2    Togo, S.H.3    Williams, S.4    Mustelin, T.5
  • 54
    • 69949170092 scopus 로고    scopus 로고
    • Activation of the PI3K pathway in cancer through inhibition of PTEN by exchange factor P-REX2a
    • 10.1126/science.1173569, 2936784, 19729658
    • Fine B, Hodakoski C, Koujak S, Su T, Saal LH, Maurer M, Hopkins B, Keniry M, Sulis ML, Mense S. Activation of the PI3K pathway in cancer through inhibition of PTEN by exchange factor P-REX2a. Science 2009, 325(5945):1261-1265. 10.1126/science.1173569, 2936784, 19729658.
    • (2009) Science , vol.325 , Issue.5945 , pp. 1261-1265
    • Fine, B.1    Hodakoski, C.2    Koujak, S.3    Su, T.4    Saal, L.H.5    Maurer, M.6    Hopkins, B.7    Keniry, M.8    Sulis, M.L.9    Mense, S.10
  • 56
    • 0036707707 scopus 로고    scopus 로고
    • Doxycycline-inducible expression of SPARC/Osteonectin/BM40 in MDA-MB-231 human breast cancer cells results in growth inhibition
    • 10.1023/A:1016536725958, 12500936
    • Dhanesuan N, Sharp JA, Blick T, Price JT, Thompson EW. Doxycycline-inducible expression of SPARC/Osteonectin/BM40 in MDA-MB-231 human breast cancer cells results in growth inhibition. Breast Cancer Res Treat 2002, 75(1):73-85. 10.1023/A:1016536725958, 12500936.
    • (2002) Breast Cancer Res Treat , vol.75 , Issue.1 , pp. 73-85
    • Dhanesuan, N.1    Sharp, J.A.2    Blick, T.3    Price, J.T.4    Thompson, E.W.5
  • 58
    • 84860477076 scopus 로고    scopus 로고
    • SPARC overexpression inhibits cell proliferation in neuroblastoma and is partly mediated by tumor suppressor protein PTEN and AKT
    • 10.1371/journal.pone.0036093, 3342296, 22567126
    • Bhoopathi P, Gorantla B, Sailaja GS, Gondi CS, Gujrati M, Klopfenstein JD, Rao JS. SPARC overexpression inhibits cell proliferation in neuroblastoma and is partly mediated by tumor suppressor protein PTEN and AKT. PLoS One 2012, 7(5):e36093. 10.1371/journal.pone.0036093, 3342296, 22567126.
    • (2012) PLoS One , vol.7 , Issue.5
    • Bhoopathi, P.1    Gorantla, B.2    Sailaja, G.S.3    Gondi, C.S.4    Gujrati, M.5    Klopfenstein, J.D.6    Rao, J.S.7
  • 59
    • 73349127477 scopus 로고    scopus 로고
    • Biomineralization in humans: making the hard choices in life
    • 10.1146/annurev-genet-102108-134242, 19659443
    • Kawasaki K, Buchanan AV, Weiss KM. Biomineralization in humans: making the hard choices in life. Annu Rev Genet 2009, 43:119-142. 10.1146/annurev-genet-102108-134242, 19659443.
    • (2009) Annu Rev Genet , vol.43 , pp. 119-142
    • Kawasaki, K.1    Buchanan, A.V.2    Weiss, K.M.3
  • 60
    • 79959478941 scopus 로고    scopus 로고
    • The evolution of milk casein genes from tooth genes before the origin of mammals
    • 10.1093/molbev/msr020, 21245413
    • Kawasaki K, Lafont AG, Sire JY. The evolution of milk casein genes from tooth genes before the origin of mammals. Mol Biol Evol 2011, 28(7):2053-2061. 10.1093/molbev/msr020, 21245413.
    • (2011) Mol Biol Evol , vol.28 , Issue.7 , pp. 2053-2061
    • Kawasaki, K.1    Lafont, A.G.2    Sire, J.Y.3
  • 61
    • 0036775425 scopus 로고    scopus 로고
    • Matricellular proteins: extracellular modulators of cell function
    • 10.1016/S0955-0674(02)00361-7, 12231357
    • Bornstein P, Sage EH. Matricellular proteins: extracellular modulators of cell function. Curr Opin Cell Biol 2002, 14(5):608-616. 10.1016/S0955-0674(02)00361-7, 12231357.
    • (2002) Curr Opin Cell Biol , vol.14 , Issue.5 , pp. 608-616
    • Bornstein, P.1    Sage, E.H.2
  • 62
    • 10644250277 scopus 로고    scopus 로고
    • SPARC and tumor growth: where the seed meets the soil?
    • 10.1002/jcb.20091, 15211566
    • Framson PE, Sage EH. SPARC and tumor growth: where the seed meets the soil?. J Cell Biochem 2004, 92(4):679-690. 10.1002/jcb.20091, 15211566.
    • (2004) J Cell Biochem , vol.92 , Issue.4 , pp. 679-690
    • Framson, P.E.1    Sage, E.H.2
  • 63
    • 55949136282 scopus 로고    scopus 로고
    • SPARC in cancer biology: its role in cancer progression and potential for therapy
    • 10.1016/j.drup.2008.08.005, 18849185
    • Tai IT, Tang MJ. SPARC in cancer biology: its role in cancer progression and potential for therapy. Drug Resist Updat 2008, 11(6):231-246. 10.1016/j.drup.2008.08.005, 18849185.
    • (2008) Drug Resist Updat , vol.11 , Issue.6 , pp. 231-246
    • Tai, I.T.1    Tang, M.J.2
  • 64
    • 77956668302 scopus 로고    scopus 로고
    • Cathepsin B facilitates autophagy-mediated apoptosis in SPARC overexpressed primitive neuroectodermal tumor cells
    • 10.1038/cdd.2010.28, 3025815, 20339379
    • Bhoopathi P, Chetty C, Gujrati M, Dinh DH, Rao JS, Lakka S. Cathepsin B facilitates autophagy-mediated apoptosis in SPARC overexpressed primitive neuroectodermal tumor cells. Cell Death Differ 2010, 17(10):1529-1539. 10.1038/cdd.2010.28, 3025815, 20339379.
    • (2010) Cell Death Differ , vol.17 , Issue.10 , pp. 1529-1539
    • Bhoopathi, P.1    Chetty, C.2    Gujrati, M.3    Dinh, D.H.4    Rao, J.S.5    Lakka, S.6
  • 65
    • 84872669783 scopus 로고    scopus 로고
    • SPARC fusion protein induces cellular adhesive signaling
    • 10.1371/journal.pone.0053202, 3549909, 23349702
    • Cheng L, Sage EH, Yan Q. SPARC fusion protein induces cellular adhesive signaling. PLoS One 2013, 8(1):e53202. 10.1371/journal.pone.0053202, 3549909, 23349702.
    • (2013) PLoS One , vol.8 , Issue.1
    • Cheng, L.1    Sage, E.H.2    Yan, Q.3
  • 66
    • 14744279741 scopus 로고    scopus 로고
    • Matricellular protein SPARC is translocated to the nuclei of immortalized murine lens epithelial cells
    • 10.1002/jcp.20226, 15534859
    • Yan Q, Weaver M, Perdue N, Sage EH. Matricellular protein SPARC is translocated to the nuclei of immortalized murine lens epithelial cells. J Cell Physiol 2005, 203(1):286-294. 10.1002/jcp.20226, 15534859.
    • (2005) J Cell Physiol , vol.203 , Issue.1 , pp. 286-294
    • Yan, Q.1    Weaver, M.2    Perdue, N.3    Sage, E.H.4
  • 67
    • 58149269841 scopus 로고    scopus 로고
    • Profilin-1 overexpression upregulates PTEN and suppresses AKT activation in breast cancer cells
    • 10.1002/jcp.21618, 2874249, 18937284
    • Das T, Bae YH, Wells A, Roy P. Profilin-1 overexpression upregulates PTEN and suppresses AKT activation in breast cancer cells. J Cell Physiol 2009, 218(2):436-443. 10.1002/jcp.21618, 2874249, 18937284.
    • (2009) J Cell Physiol , vol.218 , Issue.2 , pp. 436-443
    • Das, T.1    Bae, Y.H.2    Wells, A.3    Roy, P.4
  • 68
    • 36148972452 scopus 로고    scopus 로고
    • Profilin-1 is a negative regulator of mammary carcinoma aggressiveness
    • 10.1038/sj.bjc.6604038, 2360229, 17940506
    • Zou L, Jaramillo M, Whaley D, Wells A, Panchapakesa V, Das T, Roy P. Profilin-1 is a negative regulator of mammary carcinoma aggressiveness. Br J Cancer 2007, 97(10):1361-1371. 10.1038/sj.bjc.6604038, 2360229, 17940506.
    • (2007) Br J Cancer , vol.97 , Issue.10 , pp. 1361-1371
    • Zou, L.1    Jaramillo, M.2    Whaley, D.3    Wells, A.4    Panchapakesa, V.5    Das, T.6    Roy, P.7
  • 69
    • 73249136287 scopus 로고    scopus 로고
    • Profilin-1 overexpression restores adherens junctions in MDA-MB-231 breast cancer cells in R-cadherin-dependent manner
    • 10.1002/cm.20407, 2783708, 19593789
    • Zou L, Hazan R, Roy P. Profilin-1 overexpression restores adherens junctions in MDA-MB-231 breast cancer cells in R-cadherin-dependent manner. Cell Motil Cytoskeleton 2009, 66(12):1048-1056. 10.1002/cm.20407, 2783708, 19593789.
    • (2009) Cell Motil Cytoskeleton , vol.66 , Issue.12 , pp. 1048-1056
    • Zou, L.1    Hazan, R.2    Roy, P.3
  • 71
    • 68049085887 scopus 로고    scopus 로고
    • In vivo antitumor activity of MEK and phosphatidylinositol 3-kinase inhibitors in basal-like breast cancer models
    • 10.1158/1078-0432.CCR-09-0317, 19567590
    • Hoeflich KP, O'Brien C, Boyd Z, Cavet G, Guerrero S, Jung K, Januario T, Savage H, Punnoose E, Truong T. In vivo antitumor activity of MEK and phosphatidylinositol 3-kinase inhibitors in basal-like breast cancer models. Clin Cancer Res 2009, 15(14):4649-4664. 10.1158/1078-0432.CCR-09-0317, 19567590.
    • (2009) Clin Cancer Res , vol.15 , Issue.14 , pp. 4649-4664
    • Hoeflich, K.P.1    O'Brien, C.2    Boyd, Z.3    Cavet, G.4    Guerrero, S.5    Jung, K.6    Januario, T.7    Savage, H.8    Punnoose, E.9    Truong, T.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.