-
1
-
-
80053550020
-
Serum lipid profiles are associated with disability and MRI outcomes in multiple sclerosis
-
Weinstock-Guttman B, Zivadinov R, Mahfooz N, Carl E, Drake A, Schneider J et al. Serum lipid profiles are associated with disability and MRI outcomes in multiple sclerosis. J Neuroinflammation 2011; 8: 127
-
(2011)
J Neuroinflammation
, vol.8
, pp. 127
-
-
Weinstock-Guttman, B.1
Zivadinov, R.2
Mahfooz, N.3
Carl, E.4
Drake, A.5
Schneider, J.6
-
2
-
-
55749104704
-
A defect of sphingolipid metabolism modifies the properties of normal appearing white matter in multiple sclerosis
-
Wheeler D, Bandaru VV, Calabresi PA, Nath A, Haughey NJ. A defect of sphingolipid metabolism modifies the properties of normal appearing white matter in multiple sclerosis. Brain 2008; 131: 3092-3102
-
(2008)
Brain
, vol.131
, pp. 3092-3102
-
-
Wheeler, D.1
Bandaru, V.V.2
Calabresi, P.A.3
Nath, A.4
Haughey, N.J.5
-
3
-
-
38749143286
-
Interleukin-17 production in central nervous system-Infiltrating T cells and glial cells is associated with active disease in multiple sclerosis
-
Tzartos JS, Friese MA, Craner MJ, Palace J, Newcombe J, Esiri MM et al. Interleukin-17 production in central nervous system-Infiltrating T cells and glial cells is associated with active disease in multiple sclerosis. Am J Pathol 2008; 172: 146-155
-
(2008)
Am J Pathol
, vol.172
, pp. 146-155
-
-
Tzartos, J.S.1
Friese, M.A.2
Craner, M.J.3
Palace, J.4
Newcombe, J.5
Esiri, M.M.6
-
4
-
-
48249148236
-
IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis
-
Serada S, Fujimoto M, Mihara M, Koike N, Ohsugi Y, Nomura S et al. IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis. Proc Natl Acad Sci USA 2008; 105: 9041-9046
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 9041-9046
-
-
Serada, S.1
Fujimoto, M.2
Mihara, M.3
Koike, N.4
Ohsugi, Y.5
Nomura, S.6
-
6
-
-
78049232267
-
Intracellular trafficking of anandamide: New concepts for signaling
-
Maccarrone M, Dainese E, Oddi S. Intracellular trafficking of anandamide: New concepts for signaling. Trends Biochem Sci 2010; 35: 601-608
-
(2010)
Trends Biochem Sci
, vol.35
, pp. 601-608
-
-
Maccarrone, M.1
Dainese, E.2
Oddi, S.3
-
7
-
-
44649195035
-
Genetic deletion of fatty acid amide hydrolase results in improved long-Term outcome in chronic autoimmune encephalitis
-
Webb M, Luo L, Ma JY, Tham CS. Genetic deletion of fatty acid amide hydrolase results in improved long-Term outcome in chronic autoimmune encephalitis. Neurosci Lett 2008; 439: 106-110
-
(2008)
Neurosci Lett
, vol.439
, pp. 106-110
-
-
Webb, M.1
Luo, L.2
Ma, J.Y.3
Tham, C.S.4
-
8
-
-
67649184778
-
Regulation of Th17 differentiation by epidermal fatty acid-binding protein
-
Li B, Reynolds JM, Stout RD, Bernlohr DA, Suttles J. Regulation of Th17 differentiation by epidermal fatty acid-binding protein. J Immunol 2009; 182: 7625-7633
-
(2009)
J Immunol
, vol.182
, pp. 7625-7633
-
-
Li, B.1
Reynolds, J.M.2
Stout, R.D.3
Bernlohr, D.A.4
Suttles, J.5
-
9
-
-
78650698895
-
Functional and pathological roles of the 12-And 15-lipoxygenases
-
Dobrian AD, Lieb DC, Cole BK, Taylor-Fishwick DA, Chakrabarti SK, Nadler JL. Functional and pathological roles of the 12-And 15-lipoxygenases. Prog Lipid Res 2011; 50: 115-131
-
(2011)
Prog Lipid Res
, vol.50
, pp. 115-131
-
-
Dobrian, A.D.1
Lieb, D.C.2
Cole, B.K.3
Taylor-Fishwick, D.A.4
Chakrabarti, S.K.5
Nadler, J.L.6
-
10
-
-
0033588022
-
Lipoxygenases: Occurrence, functions, catalysis, and acquisition of substrate
-
Brash AR. Lipoxygenases: Occurrence, functions, catalysis, and acquisition of substrate. J Biol Chem 1999; 274: 23679-23682
-
(1999)
J Biol Chem
, vol.274
, pp. 23679-23682
-
-
Brash, A.R.1
-
11
-
-
32544451437
-
Relationship of plasma polyunsaturated fatty acids to circulating inflammatory markers
-
Ferrucci L, Cherubini A, Bandinelli S, Bartali B, Corsi A, Lauretani F et al. Relationship of plasma polyunsaturated fatty acids to circulating inflammatory markers. J Clin Endocrinol Metab 2006; 91: 439-446
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 439-446
-
-
Ferrucci, L.1
Cherubini, A.2
Bandinelli, S.3
Bartali, B.4
Corsi, A.5
Lauretani, F.6
-
12
-
-
0346494718
-
Effects of dietary supplementation with arachidonic acid on platelet and renal function in patients with cirrhosis
-
Pantaleo P, Marra F, Vizzutti F, Spadoni S, Ciabattoni G, Galli C et al. Effects of dietary supplementation with arachidonic acid on platelet and renal function in patients with cirrhosis. Clin Sci (Lond) 2004; 106: 27-34
-
(2004)
Clin Sci (Lond
, vol.106
, pp. 27-34
-
-
Pantaleo, P.1
Marra, F.2
Vizzutti, F.3
Spadoni, S.4
Ciabattoni, G.5
Galli, C.6
-
13
-
-
0033595261
-
Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase
-
Huang JT, Welch JS, Ricote M, Binder CJ, Willson TM, Kelly C et al. Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase. Nature 1999; 400: 378-382
-
(1999)
Nature
, vol.400
, pp. 378-382
-
-
Huang, J.T.1
Welch, J.S.2
Ricote, M.3
Binder, C.J.4
Willson, T.M.5
Kelly, C.6
-
14
-
-
0027505377
-
Arachidonate 12-lipoxygenase is localized in neurons, glial cells, and endothelial cells of the canine brain
-
Nishiyama M, Watanabe T, Ueda N, Tsukamoto H, Watanabe K. Arachidonate 12-lipoxygenase is localized in neurons, glial cells, and endothelial cells of the canine brain. J Histochem Cytochem 1993; 41: 111-117
-
(1993)
J Histochem Cytochem
, vol.41
, pp. 111-117
-
-
Nishiyama, M.1
Watanabe, T.2
Ueda, N.3
Tsukamoto, H.4
Watanabe, K.5
-
15
-
-
0028954199
-
Localization of 12-lipoxygenase mRNA in cultured oligodendrocytes and astrocytes by in situ reverse transcriptase and polymerase chain reaction
-
Bendani MK, Palluy O, Cook-Moreau J, Beneytout JL, Rigaud M, Vallat JM. Localization of 12-lipoxygenase mRNA in cultured oligodendrocytes and astrocytes by in situ reverse transcriptase and polymerase chain reaction. Neurosci Lett 1995; 189: 159-162
-
(1995)
Neurosci Lett
, vol.189
, pp. 159-162
-
-
Bendani, M.K.1
Palluy, O.2
Cook-Moreau, J.3
Beneytout, J.L.4
Rigaud, M.5
Vallat, J.M.6
-
16
-
-
84856146554
-
Transcriptional regulation of beta-secretase-1 by 12/15-lipoxygenase results in enhanced amyloidogenesis and cognitive impairments
-
Chu J, Zhuo JM, Pratico D. Transcriptional regulation of beta-secretase-1 by 12/15-lipoxygenase results in enhanced amyloidogenesis and cognitive impairments. Ann Neurol 2012; 71: 57-67
-
(2012)
Ann Neurol
, vol.71
, pp. 57-67
-
-
Chu, J.1
Zhuo, J.M.2
Pratico, D.3
-
17
-
-
78049423493
-
Amelioration of the Alzheimer's disease phenotype by absence of 12/15-lipoxygenase
-
Yang H, Zhuo JM, Chu J, Chinnici C, Pratico D. Amelioration of the Alzheimer's disease phenotype by absence of 12/15-lipoxygenase. Biol Psychiatry 2010; 68: 922-929
-
(2010)
Biol Psychiatry
, vol.68
, pp. 922-929
-
-
Yang, H.1
Zhuo, J.M.2
Chu, J.3
Chinnici, C.4
Pratico, D.5
-
18
-
-
0030867994
-
A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion
-
Li Y, Maher P, Schubert D. A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion. Neuron 1997; 19: 453-463
-
(1997)
Neuron
, vol.19
, pp. 453-463
-
-
Li, Y.1
Maher, P.2
Schubert, D.3
-
19
-
-
4344661069
-
Experimental allergic encephalomyelitis is exacerbated in mice deficient for 12/15-lipoxygenase or 5-lipoxygenase
-
Emerson MR, LeVine SM. Experimental allergic encephalomyelitis is exacerbated in mice deficient for 12/15-lipoxygenase or 5-lipoxygenase. Brain Res 2004; 1021: 140-145
-
(2004)
Brain Res
, vol.1021
, pp. 140-145
-
-
Emerson, M.R.1
LeVine, S.M.2
-
20
-
-
0034713444
-
Roles of PPARs in health and disease
-
Kersten S, Desvergne B, Wahli W. Roles of PPARs in health and disease. Nature 2000; 405: 421-424
-
(2000)
Nature
, vol.405
, pp. 421-424
-
-
Kersten, S.1
Desvergne, B.2
Wahli, W.3
-
21
-
-
84863104065
-
PPARs at the crossroads of lipid signaling and inflammation
-
Wahli W, Michalik L. PPARs at the crossroads of lipid signaling and inflammation. Trends Endocrinol Metab 2012; 23: 351-363
-
(2012)
Trends Endocrinol Metab
, vol.23
, pp. 351-363
-
-
Wahli, W.1
Michalik, L.2
-
22
-
-
84860209867
-
Antiinflammatory effect of simvastatin in an experimental model of spinal cord trauma: Involvement of PPAR-Alpha
-
Esposito E, Rinaldi B, Mazzon E, Donniacuo M, Impellizzeri D, Paterniti I et al. Antiinflammatory effect of simvastatin in an experimental model of spinal cord trauma: Involvement of PPAR-Alpha. J Neuroinflammation 2012; 9: 81
-
(2012)
J Neuroinflammation
, vol.9
, pp. 81
-
-
Esposito, E.1
Rinaldi, B.2
Mazzon, E.3
Donniacuo, M.4
Impellizzeri, D.5
Paterniti, I.6
-
23
-
-
84859349600
-
The PPAR-gamma agonist pioglitazone protects cortical neurons from inflammatory mediators via improvement in peroxisomal function
-
Gray E, Ginty M, Kemp K, Scolding N, Wilkins A. The PPAR-gamma agonist pioglitazone protects cortical neurons from inflammatory mediators via improvement in peroxisomal function. J Neuroinflammation 2012; 9: 63
-
(2012)
J Neuroinflammation
, vol.9
, pp. 63
-
-
Gray, E.1
Ginty, M.2
Kemp, K.3
Scolding, N.4
Wilkins, A.5
-
24
-
-
33646177187
-
Baicalein is a potent in vitro inhibitor against both reticulocyte 15-human and platelet 12-human lipoxygenases
-
Deschamps JD, Kenyon VA, Holman TR. Baicalein is a potent in vitro inhibitor against both reticulocyte 15-human and platelet 12-human lipoxygenases. Bioorg Med Chem 2006; 14: 4295-4301
-
(2006)
Bioorg Med Chem
, vol.14
, pp. 4295-4301
-
-
Deschamps, J.D.1
Kenyon, V.A.2
Holman, T.R.3
-
25
-
-
33845442015
-
Baicalein LoEH and 12/15-lipoxygenase in the ischemic brain
-
van Leyen K, Kim HY, Lee SR, Jin G, Arai K, Baicalein LoEH. and 12/15-lipoxygenase in the ischemic brain. Stroke 2006; 37: 3014-3018
-
(2006)
Stroke
, vol.37
, pp. 3014-3018
-
-
Van Leyen, K.1
Kim, H.Y.2
Lee, S.R.3
Jin, G.4
Arai, K.5
-
26
-
-
0028067008
-
The immunopathogenesis and regulation of T-cell-mediated demyelinating diseases
-
Miller SD, Karpus WJ. The immunopathogenesis and regulation of T-cell-mediated demyelinating diseases. Immunol Today 1994; 15: 356-361
-
(1994)
Immunol Today
, vol.15
, pp. 356-361
-
-
Miller, S.D.1
Karpus, W.J.2
-
27
-
-
84864603265
-
Clusters of activated microglia in normal-Appearing white matter show signs of innate immune activation
-
van Horssen J, Singh S, van der Pol S, Kipp M, Lim JL, Peferoen L et al. Clusters of activated microglia in normal-Appearing white matter show signs of innate immune activation. J Neuroinflammation 2012; 9: 156
-
(2012)
J Neuroinflammation
, vol.9
, pp. 156
-
-
Van Horssen, J.1
Singh, S.2
Van Der Pol, S.3
Kipp, M.4
Lim, J.L.5
Peferoen, L.6
-
28
-
-
84863088484
-
Neuroimmune crosstalk in the central nervous system and its significance for neurological diseases
-
Tian L, Ma L, Kaarela T, Li Z. Neuroimmune crosstalk in the central nervous system and its significance for neurological diseases. J Neuroinflammation 2012; 9: 155
-
(2012)
J Neuroinflammation
, vol.9
, pp. 155
-
-
Tian, L.1
Ma, L.2
Kaarela, T.3
Li, Z.4
-
29
-
-
20044376483
-
Experimental autoimmune encephalomyelitis repressed by microglial paralysis
-
Heppner FL, Greter M, Marino D, Falsig J, Raivich G, Hovelmeyer N et al. Experimental autoimmune encephalomyelitis repressed by microglial paralysis. Nat Med 2005; 11: 146-152
-
(2005)
Nat Med
, vol.11
, pp. 146-152
-
-
Heppner, F.L.1
Greter, M.2
Marino, D.3
Falsig, J.4
Raivich, G.5
Hovelmeyer, N.6
-
30
-
-
77952571744
-
Genetic ablation of steroid receptor coactivator-3 promotes PPAR-beta-mediated alternative activation of microglia in experimental autoimmune encephalomyelitis
-
Xiao Y, Xu J, Wang S, Mao C, Jin M, Ning G et al. Genetic ablation of steroid receptor coactivator-3 promotes PPAR-beta-mediated alternative activation of microglia in experimental autoimmune encephalomyelitis. Glia 2010; 58: 932-942
-
(2010)
Glia
, vol.58
, pp. 932-942
-
-
Xiao, Y.1
Xu, J.2
Wang, S.3
Mao, C.4
Jin, M.5
Ning, G.6
-
31
-
-
79952217413
-
Regulation of immune responses and autoimmune encephalomyelitis by PPARs
-
Yang Y, Lovett-Racke AE, Racke MK. Regulation of immune responses and autoimmune encephalomyelitis by PPARs. PPAR Res 2010; 2010: 104705
-
(2010)
PPAR Res
, vol.2010
, pp. 104705
-
-
Yang, Y.1
Lovett-Racke, A.E.2
Racke, M.K.3
-
32
-
-
70749160209
-
12/15-Lipoxygenase inhibitor baicalein suppresses PPAR gamma expression and nuclear translocation induced by cerebral ischemia/reperfusion
-
Xu YW, Sun L, Liang H, Sun GM, Cheng Y. 12/15-Lipoxygenase inhibitor baicalein suppresses PPAR gamma expression and nuclear translocation induced by cerebral ischemia/reperfusion. Brain Res 2010; 1307: 149-157
-
(2010)
Brain Res
, vol.1307
, pp. 149-157
-
-
Xu, Y.W.1
Sun, L.2
Liang, H.3
Sun, G.M.4
Cheng, Y.5
-
34
-
-
66449124004
-
Effects of the PPARbeta agonist GW501516 in an in vitro model of brain inflammation and antibody-Induced demyelination
-
Defaux A, Zurich MG, Braissant O, Honegger P, Monnet-Tschudi F. Effects of the PPARbeta agonist GW501516 in an in vitro model of brain inflammation and antibody-Induced demyelination. J Neuroinflammation 2009; 6: 15
-
(2009)
J Neuroinflammation
, vol.6
, pp. 15
-
-
Defaux, A.1
Zurich, M.G.2
Braissant, O.3
Honegger, P.4
Monnet-Tschudi, F.5
-
35
-
-
0030047806
-
Differential expression of peroxisome proliferator-Activated receptors (PPARs): Tissue distribution of PPAR-Alpha, beta, and -gamma in the adult rat
-
Braissant O, Foufelle F, Scotto C, Dauca M, Wahli W. Differential expression of peroxisome proliferator-Activated receptors (PPARs): Tissue distribution of PPAR-Alpha, -beta, and -gamma in the adult rat. Endocrinology 1996; 137: 354-366
-
(1996)
Endocrinology
, vol.137
, pp. 354-366
-
-
Braissant, O.1
Foufelle, F.2
Scotto, C.3
Dauca, M.4
Wahli, W.5
-
36
-
-
0034141545
-
The nuclear receptor PPAR gamma and immunoregulation: PPAR gamma mediates inhibition of helper T cell responses
-
Clark RB, Bishop-Bailey D, Estrada-Hernandez T, Hla T, Puddington L, Padula SJ. The nuclear receptor PPAR gamma and immunoregulation: PPAR gamma mediates inhibition of helper T cell responses. J Immunol 2000; 164: 1364-1371
-
(2000)
J Immunol
, vol.164
, pp. 1364-1371
-
-
Clark, R.B.1
Bishop-Bailey, D.2
Estrada-Hernandez, T.3
Hla, T.4
Puddington, L.5
Padula, S.J.6
-
37
-
-
0034660182
-
Peroxisome proliferator-Activated receptor-gamma activators inhibit IFN-gamma-Induced expression of the T cell-Active CXC chemokines IP-10, Mig, and I-TAC in human endothelial cells
-
Marx N, Mach F, Sauty A, Leung JH, Sarafi MN, Ransohoff RM et al. Peroxisome proliferator-Activated receptor-gamma activators inhibit IFN-gamma-Induced expression of the T cell-Active CXC chemokines IP-10, Mig, and I-TAC in human endothelial cells. J Immunol 2000; 164: 6503-6508
-
(2000)
J Immunol
, vol.164
, pp. 6503-6508
-
-
Marx, N.1
Mach, F.2
Sauty, A.3
Leung, J.H.4
Sarafi, M.N.5
Ransohoff, R.M.6
-
38
-
-
0036546185
-
Peroxisome proliferator-Activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation
-
Natarajan C, Bright JJ. Peroxisome proliferator-Activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation. Genes Immun 2002; 3: 59-70
-
(2002)
Genes Immun
, vol.3
, pp. 59-70
-
-
Natarajan, C.1
Bright, J.J.2
-
39
-
-
1542313910
-
Anti-Inflammatory and antiproliferative actions of PPAR-gamma agonists on T lymphocytes derived from MS patients
-
Schmidt S, Moric E, Schmidt M, Sastre M, Feinstein DL, Heneka MT. Anti-Inflammatory and antiproliferative actions of PPAR-gamma agonists on T lymphocytes derived from MS patients. J Leukoc Biol 2004; 75: 478-485
-
(2004)
J Leukoc Biol
, vol.75
, pp. 478-485
-
-
Schmidt, S.1
Moric, E.2
Schmidt, M.3
Sastre, M.4
Feinstein, D.L.5
Heneka, M.T.6
-
40
-
-
2142787409
-
Peroxisome proliferator-Activated receptor gamma (PPAR-gamma) activation in naive mouse T cells induces cell death
-
Harris SG, Phipps RP. Peroxisome proliferator-Activated receptor gamma (PPAR-gamma) activation in naive mouse T cells induces cell death. Ann N Y Acad Sci 2000; 905: 297-300
-
(2000)
Ann N Y Acad Sci
, vol.905
, pp. 297-300
-
-
Harris, S.G.1
Phipps, R.P.2
-
41
-
-
0037487144
-
Activation-Induced PPARgamma expression sensitizes primary human T cells toward apoptosis
-
Tautenhahn A, Brune B, von Knethen A. Activation-Induced PPARgamma expression sensitizes primary human T cells toward apoptosis. J Leukoc Biol 2003; 73: 665-672
-
(2003)
J Leukoc Biol
, vol.73
, pp. 665-672
-
-
Tautenhahn, A.1
Brune, B.2
Von Knethen, A.3
-
42
-
-
0032911057
-
The diversity of the lipoxygenase family Many sequence data but little information on biological significance
-
Kuhn H, Thiele BJ. The diversity of the lipoxygenase family. Many sequence data but little information on biological significance. FEBS Lett 1999; 449: 7-11
-
(1999)
FEBS Lett
, vol.449
, pp. 7-11
-
-
Kuhn, H.1
Thiele, B.J.2
-
43
-
-
0029844659
-
Disruption of 12/15-lipoxygenase expression in peritoneal macrophages. Enhanced utilization of the 5-lipoxygenase pathway and diminished oxidation of low density lipoprotein
-
Sun D, Funk CD. Disruption of 12/15-lipoxygenase expression in peritoneal macrophages. Enhanced utilization of the 5-lipoxygenase pathway and diminished oxidation of low density lipoprotein. J Biol Chem 1996; 271: 24055-24062
-
(1996)
J Biol Chem
, vol.271
, pp. 24055-24062
-
-
Sun, D.1
Funk, C.D.2
-
44
-
-
20844446795
-
Critical role of macrophage 12/15-lipoxygenase for atherosclerosis in apolipoprotein E-deficient mice
-
Huo Y, Zhao L, Hyman MC, Shashkin P, Harry BL, Burcin T et al. Critical role of macrophage 12/15-lipoxygenase for atherosclerosis in apolipoprotein E-deficient mice. Circulation 2004; 110: 2024-2031
-
(2004)
Circulation
, vol.110
, pp. 2024-2031
-
-
Huo, Y.1
Zhao, L.2
Hyman, M.C.3
Shashkin, P.4
Harry, B.L.5
Burcin, T.6
-
45
-
-
27644571486
-
12/15-Lipoxygenase regulates intercellular adhesion molecule-1 expression and monocyte adhesion to endothelium through activation of RhoA and nuclear factor-kappaB
-
Bolick DT, Orr AW, Whetzel A, Srinivasan S, Hatley ME, Schwartz MA et al. 12/15-Lipoxygenase regulates intercellular adhesion molecule-1 expression and monocyte adhesion to endothelium through activation of RhoA and nuclear factor-kappaB. Arterioscler Thromb Vasc Biol 2005; 25: 2301-2307
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 2301-2307
-
-
Bolick, D.T.1
Orr, A.W.2
Whetzel, A.3
Srinivasan, S.4
Hatley, M.E.5
Schwartz, M.A.6
-
46
-
-
68949116297
-
Dual 12/15-And 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice
-
Poeckel D, Zemski Berry KA, Murphy RC, Funk CD. Dual 12/15-And 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice. J Biol Chem 2009; 284: 21077-21089
-
(2009)
J Biol Chem
, vol.284
, pp. 21077-21089
-
-
Poeckel, D.1
Zemski Berry, K.A.2
Murphy, R.C.3
Funk, C.D.4
-
47
-
-
0028874383
-
Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat
-
Tokuyama Y, Sturis J, DePaoli AM, Takeda J, Stoffel M, Tang J et al. Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat. Diabetes 1995; 44: 1447-1457
-
(1995)
Diabetes
, vol.44
, pp. 1447-1457
-
-
Tokuyama, Y.1
Sturis, J.2
DePaoli, A.M.3
Takeda, J.4
Stoffel, M.5
Tang, J.6
-
48
-
-
0032723345
-
Resistance to type 1 diabetes induction in 12-lipoxygenase knockout mice
-
Bleich D, Chen S, Zipser B, Sun D, Funk CD, Nadler JL. Resistance to type 1 diabetes induction in 12-lipoxygenase knockout mice. J Clin Invest 1999; 103: 1431-1436
-
(1999)
J Clin Invest
, vol.103
, pp. 1431-1436
-
-
Bleich, D.1
Chen, S.2
Zipser, B.3
Sun, D.4
Funk, C.D.5
Nadler, J.L.6
-
49
-
-
84859417816
-
Macrophage 12/15 lipoxygenase expression increases plasma and hepatic lipid levels and exacerbates atherosclerosis
-
Rong S, Cao Q, Liu M, Seo J, Jia L, Boudyguina E et al. Macrophage 12/15 lipoxygenase expression increases plasma and hepatic lipid levels and exacerbates atherosclerosis. J Lipid Res 2012; 53: 686-695
-
(2012)
J Lipid Res
, vol.53
, pp. 686-695
-
-
Rong, S.1
Cao, Q.2
Liu, M.3
Seo, J.4
Jia, L.5
Boudyguina, E.6
-
50
-
-
57349164262
-
Mice lacking 12/15-lipoxygenase have attenuated airway allergic inflammation and remodeling
-
Andersson CK, Claesson HE, Rydell-Tormanen K, Swedmark S, Hallgren A, Erjefalt JS. Mice lacking 12/15-lipoxygenase have attenuated airway allergic inflammation and remodeling. Am J Respir Cell Mol Biol 2008; 39: 648-656
-
(2008)
Am J Respir Cell Mol Biol
, vol.39
, pp. 648-656
-
-
Andersson, C.K.1
Claesson, H.E.2
Rydell-Tormanen, K.3
Swedmark, S.4
Hallgren, A.5
Erjefalt, J.S.6
-
51
-
-
42049114647
-
5-Lipoxygenase gene disruption reduces amyloid-beta pathology in a mouse model of Alzheimer's disease
-
Firuzi O, Zhuo J, Chinnici CM, Wisniewski T, Pratico D. 5-Lipoxygenase gene disruption reduces amyloid-beta pathology in a mouse model of Alzheimer's disease. FASEB J 2008; 22: 1169-1178
-
(2008)
FASEB J
, vol.22
, pp. 1169-1178
-
-
Firuzi, O.1
Zhuo, J.2
Chinnici, C.M.3
Wisniewski, T.4
Pratico, D.5
-
52
-
-
77952150495
-
Immunopharmacological role of the leukotriene receptor antagonists and inhibitors of leukotrienes generating enzymes in multiple sclerosis
-
Mirshafiey A, Jadidi-Niaragh F. Immunopharmacological role of the leukotriene receptor antagonists and inhibitors of leukotrienes generating enzymes in multiple sclerosis. Immunopharmacol Immunotoxicol 2010; 32: 219-227
-
(2010)
Immunopharmacol Immunotoxicol
, vol.32
, pp. 219-227
-
-
Mirshafiey, A.1
Jadidi-Niaragh, F.2
-
53
-
-
25844473319
-
Protective effects of a peroxisome proliferator-Activated receptor-beta/delta agonist in experimental autoimmune encephalomyelitis
-
Polak PE, Kalinin S, Dello Russo C, Gavrilyuk V, Sharp A, Peters JM et al. Protective effects of a peroxisome proliferator-Activated receptor-beta/delta agonist in experimental autoimmune encephalomyelitis. J Neuroimmunology 2005; 168: 65-75
-
(2005)
J Neuroimmunology
, vol.168
, pp. 65-75
-
-
Polak, P.E.1
Kalinin, S.2
Dello Russo, C.3
Gavrilyuk, V.4
Sharp, A.5
Peters, J.M.6
-
54
-
-
77955343205
-
Peroxisome proliferatoractivated receptor delta limits the expansion of pathogenic Th cells during central nervous system autoimmunity
-
Dunn SE, Bhat R, Straus DS, Sobel RA, Axtell R, Johnson A et al. Peroxisome proliferatoractivated receptor delta limits the expansion of pathogenic Th cells during central nervous system autoimmunity. J Exp Med 2010; 207: 1599-1608
-
(2010)
J Exp Med
, vol.207
, pp. 1599-1608
-
-
Dunn, S.E.1
Bhat, R.2
Straus, D.S.3
Sobel, R.A.4
Axtell, R.5
Johnson, A.6
-
55
-
-
12244308528
-
The effects of the cyclosporin A, a P-glycoprotein inhibitor, on the pharmacokinetics of baicalein in the rat: A microdialysis study
-
Tsai TH, Liu SC, Tsai PL, Ho LK, Shum AY, Chen CF. The effects of the cyclosporin A, a P-glycoprotein inhibitor, on the pharmacokinetics of baicalein in the rat: A microdialysis study. Br J Pharmacol 2002; 137: 1314-1320
-
(2002)
Br J Pharmacol
, vol.137
, pp. 1314-1320
-
-
Tsai, T.H.1
Liu, S.C.2
Tsai, P.L.3
Ho, L.K.4
Shum, A.Y.5
Chen, C.F.6
-
56
-
-
0037168869
-
PPARalpha and PPARdelta activators inhibit cytokine-Induced nuclear translocation of NFkappaB and expression of VCAM-1 in EAhy926 endothelial cells
-
Rival Y, Beneteau N, Taillandier T, Pezet M, Dupont-Passelaigue E, Patoiseau JF et al. PPARalpha and PPARdelta activators inhibit cytokine-Induced nuclear translocation of NFkappaB and expression of VCAM-1 in EAhy926 endothelial cells. Eur J Pharmacol 2002; 435: 143-151
-
(2002)
Eur J Pharmacol
, vol.435
, pp. 143-151
-
-
Rival, Y.1
Beneteau, N.2
Taillandier, T.3
Pezet, M.4
Dupont-Passelaigue, E.5
Patoiseau, J.F.6
-
57
-
-
57649155050
-
Inflammatory pathways are activated during cardiomyocyte hypertrophy and attenuated by peroxisome proliferator-Activated receptors PPARalpha and PPARdelta
-
Smeets PJ, Teunissen BE, Planavila A, de Vogel-van den Bosch H, Willemsen PH, van der Vusse GJ et al. Inflammatory pathways are activated during cardiomyocyte hypertrophy and attenuated by peroxisome proliferator-Activated receptors PPARalpha and PPARdelta. J Biol Chem 2008; 283: 29109-29118
-
(2008)
J Biol Chem
, vol.283
, pp. 29109-29118
-
-
Smeets, P.J.1
Teunissen, B.E.2
Planavila, A.3
De Vogel-Van Den Bosch, H.4
Willemsen, P.H.5
Van Der Vusse, G.J.6
-
58
-
-
50949105881
-
Activation of peroxisome proliferator-Activated receptor beta/delta inhibits lipopolysaccharide-Induced cytokine production in adipocytes by lowering nuclear factor-kappaB activity via extracellular signal-related kinase 1/2
-
Rodriguez-Calvo R, Serrano L, Coll T, Moullan N, Sanchez RM, Merlos M et al. Activation of peroxisome proliferator-Activated receptor beta/delta inhibits lipopolysaccharide-Induced cytokine production in adipocytes by lowering nuclear factor-kappaB activity via extracellular signal-related kinase 1/2. Diabetes 2008; 57: 2149-2157
-
(2008)
Diabetes
, vol.57
, pp. 2149-2157
-
-
Rodriguez-Calvo, R.1
Serrano, L.2
Coll, T.3
Moullan, N.4
Sanchez, R.M.5
Merlos, M.6
|