메뉴 건너뛰기




Volumn 4, Issue 4, 2013, Pages

P38MAPK inhibition: A new combined approach to reduce neuroblastoma resistance under etoposide treatment

Author keywords

Etoposide; MAPK; Neuroblastoma

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CHEMOKINE RECEPTOR; CYCLOOXYGENASE 2; ETOPOSIDE; GELATINASE B; INTERCELLULAR ADHESION MOLECULE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; ANTINEOPLASTIC AGENT; ENZYME INHIBITOR; IMIDAZOLE DERIVATIVE; PYRIDINE DERIVATIVE; TUMOR PROTEIN;

EID: 84876887873     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2013.118     Document Type: Article
Times cited : (31)

References (58)
  • 2
    • 55749104704 scopus 로고    scopus 로고
    • A defect of sphingolipid metabolism modifies the properties of normal appearing white matter in multiple sclerosis
    • Wheeler D, Bandaru VV, Calabresi PA, Nath A, Haughey NJ. A defect of sphingolipid metabolism modifies the properties of normal appearing white matter in multiple sclerosis. Brain 2008; 131: 3092-3102
    • (2008) Brain , vol.131 , pp. 3092-3102
    • Wheeler, D.1    Bandaru, V.V.2    Calabresi, P.A.3    Nath, A.4    Haughey, N.J.5
  • 3
    • 38749143286 scopus 로고    scopus 로고
    • Interleukin-17 production in central nervous system-Infiltrating T cells and glial cells is associated with active disease in multiple sclerosis
    • Tzartos JS, Friese MA, Craner MJ, Palace J, Newcombe J, Esiri MM et al. Interleukin-17 production in central nervous system-Infiltrating T cells and glial cells is associated with active disease in multiple sclerosis. Am J Pathol 2008; 172: 146-155
    • (2008) Am J Pathol , vol.172 , pp. 146-155
    • Tzartos, J.S.1    Friese, M.A.2    Craner, M.J.3    Palace, J.4    Newcombe, J.5    Esiri, M.M.6
  • 4
    • 48249148236 scopus 로고    scopus 로고
    • IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis
    • Serada S, Fujimoto M, Mihara M, Koike N, Ohsugi Y, Nomura S et al. IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis. Proc Natl Acad Sci USA 2008; 105: 9041-9046
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 9041-9046
    • Serada, S.1    Fujimoto, M.2    Mihara, M.3    Koike, N.4    Ohsugi, Y.5    Nomura, S.6
  • 6
    • 78049232267 scopus 로고    scopus 로고
    • Intracellular trafficking of anandamide: New concepts for signaling
    • Maccarrone M, Dainese E, Oddi S. Intracellular trafficking of anandamide: New concepts for signaling. Trends Biochem Sci 2010; 35: 601-608
    • (2010) Trends Biochem Sci , vol.35 , pp. 601-608
    • Maccarrone, M.1    Dainese, E.2    Oddi, S.3
  • 7
    • 44649195035 scopus 로고    scopus 로고
    • Genetic deletion of fatty acid amide hydrolase results in improved long-Term outcome in chronic autoimmune encephalitis
    • Webb M, Luo L, Ma JY, Tham CS. Genetic deletion of fatty acid amide hydrolase results in improved long-Term outcome in chronic autoimmune encephalitis. Neurosci Lett 2008; 439: 106-110
    • (2008) Neurosci Lett , vol.439 , pp. 106-110
    • Webb, M.1    Luo, L.2    Ma, J.Y.3    Tham, C.S.4
  • 8
    • 67649184778 scopus 로고    scopus 로고
    • Regulation of Th17 differentiation by epidermal fatty acid-binding protein
    • Li B, Reynolds JM, Stout RD, Bernlohr DA, Suttles J. Regulation of Th17 differentiation by epidermal fatty acid-binding protein. J Immunol 2009; 182: 7625-7633
    • (2009) J Immunol , vol.182 , pp. 7625-7633
    • Li, B.1    Reynolds, J.M.2    Stout, R.D.3    Bernlohr, D.A.4    Suttles, J.5
  • 10
    • 0033588022 scopus 로고    scopus 로고
    • Lipoxygenases: Occurrence, functions, catalysis, and acquisition of substrate
    • Brash AR. Lipoxygenases: Occurrence, functions, catalysis, and acquisition of substrate. J Biol Chem 1999; 274: 23679-23682
    • (1999) J Biol Chem , vol.274 , pp. 23679-23682
    • Brash, A.R.1
  • 12
    • 0346494718 scopus 로고    scopus 로고
    • Effects of dietary supplementation with arachidonic acid on platelet and renal function in patients with cirrhosis
    • Pantaleo P, Marra F, Vizzutti F, Spadoni S, Ciabattoni G, Galli C et al. Effects of dietary supplementation with arachidonic acid on platelet and renal function in patients with cirrhosis. Clin Sci (Lond) 2004; 106: 27-34
    • (2004) Clin Sci (Lond , vol.106 , pp. 27-34
    • Pantaleo, P.1    Marra, F.2    Vizzutti, F.3    Spadoni, S.4    Ciabattoni, G.5    Galli, C.6
  • 13
    • 0033595261 scopus 로고    scopus 로고
    • Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase
    • Huang JT, Welch JS, Ricote M, Binder CJ, Willson TM, Kelly C et al. Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase. Nature 1999; 400: 378-382
    • (1999) Nature , vol.400 , pp. 378-382
    • Huang, J.T.1    Welch, J.S.2    Ricote, M.3    Binder, C.J.4    Willson, T.M.5    Kelly, C.6
  • 14
    • 0027505377 scopus 로고
    • Arachidonate 12-lipoxygenase is localized in neurons, glial cells, and endothelial cells of the canine brain
    • Nishiyama M, Watanabe T, Ueda N, Tsukamoto H, Watanabe K. Arachidonate 12-lipoxygenase is localized in neurons, glial cells, and endothelial cells of the canine brain. J Histochem Cytochem 1993; 41: 111-117
    • (1993) J Histochem Cytochem , vol.41 , pp. 111-117
    • Nishiyama, M.1    Watanabe, T.2    Ueda, N.3    Tsukamoto, H.4    Watanabe, K.5
  • 15
    • 0028954199 scopus 로고
    • Localization of 12-lipoxygenase mRNA in cultured oligodendrocytes and astrocytes by in situ reverse transcriptase and polymerase chain reaction
    • Bendani MK, Palluy O, Cook-Moreau J, Beneytout JL, Rigaud M, Vallat JM. Localization of 12-lipoxygenase mRNA in cultured oligodendrocytes and astrocytes by in situ reverse transcriptase and polymerase chain reaction. Neurosci Lett 1995; 189: 159-162
    • (1995) Neurosci Lett , vol.189 , pp. 159-162
    • Bendani, M.K.1    Palluy, O.2    Cook-Moreau, J.3    Beneytout, J.L.4    Rigaud, M.5    Vallat, J.M.6
  • 16
    • 84856146554 scopus 로고    scopus 로고
    • Transcriptional regulation of beta-secretase-1 by 12/15-lipoxygenase results in enhanced amyloidogenesis and cognitive impairments
    • Chu J, Zhuo JM, Pratico D. Transcriptional regulation of beta-secretase-1 by 12/15-lipoxygenase results in enhanced amyloidogenesis and cognitive impairments. Ann Neurol 2012; 71: 57-67
    • (2012) Ann Neurol , vol.71 , pp. 57-67
    • Chu, J.1    Zhuo, J.M.2    Pratico, D.3
  • 17
    • 78049423493 scopus 로고    scopus 로고
    • Amelioration of the Alzheimer's disease phenotype by absence of 12/15-lipoxygenase
    • Yang H, Zhuo JM, Chu J, Chinnici C, Pratico D. Amelioration of the Alzheimer's disease phenotype by absence of 12/15-lipoxygenase. Biol Psychiatry 2010; 68: 922-929
    • (2010) Biol Psychiatry , vol.68 , pp. 922-929
    • Yang, H.1    Zhuo, J.M.2    Chu, J.3    Chinnici, C.4    Pratico, D.5
  • 18
    • 0030867994 scopus 로고    scopus 로고
    • A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion
    • Li Y, Maher P, Schubert D. A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion. Neuron 1997; 19: 453-463
    • (1997) Neuron , vol.19 , pp. 453-463
    • Li, Y.1    Maher, P.2    Schubert, D.3
  • 19
    • 4344661069 scopus 로고    scopus 로고
    • Experimental allergic encephalomyelitis is exacerbated in mice deficient for 12/15-lipoxygenase or 5-lipoxygenase
    • Emerson MR, LeVine SM. Experimental allergic encephalomyelitis is exacerbated in mice deficient for 12/15-lipoxygenase or 5-lipoxygenase. Brain Res 2004; 1021: 140-145
    • (2004) Brain Res , vol.1021 , pp. 140-145
    • Emerson, M.R.1    LeVine, S.M.2
  • 20
    • 0034713444 scopus 로고    scopus 로고
    • Roles of PPARs in health and disease
    • Kersten S, Desvergne B, Wahli W. Roles of PPARs in health and disease. Nature 2000; 405: 421-424
    • (2000) Nature , vol.405 , pp. 421-424
    • Kersten, S.1    Desvergne, B.2    Wahli, W.3
  • 21
    • 84863104065 scopus 로고    scopus 로고
    • PPARs at the crossroads of lipid signaling and inflammation
    • Wahli W, Michalik L. PPARs at the crossroads of lipid signaling and inflammation. Trends Endocrinol Metab 2012; 23: 351-363
    • (2012) Trends Endocrinol Metab , vol.23 , pp. 351-363
    • Wahli, W.1    Michalik, L.2
  • 22
    • 84860209867 scopus 로고    scopus 로고
    • Antiinflammatory effect of simvastatin in an experimental model of spinal cord trauma: Involvement of PPAR-Alpha
    • Esposito E, Rinaldi B, Mazzon E, Donniacuo M, Impellizzeri D, Paterniti I et al. Antiinflammatory effect of simvastatin in an experimental model of spinal cord trauma: Involvement of PPAR-Alpha. J Neuroinflammation 2012; 9: 81
    • (2012) J Neuroinflammation , vol.9 , pp. 81
    • Esposito, E.1    Rinaldi, B.2    Mazzon, E.3    Donniacuo, M.4    Impellizzeri, D.5    Paterniti, I.6
  • 23
    • 84859349600 scopus 로고    scopus 로고
    • The PPAR-gamma agonist pioglitazone protects cortical neurons from inflammatory mediators via improvement in peroxisomal function
    • Gray E, Ginty M, Kemp K, Scolding N, Wilkins A. The PPAR-gamma agonist pioglitazone protects cortical neurons from inflammatory mediators via improvement in peroxisomal function. J Neuroinflammation 2012; 9: 63
    • (2012) J Neuroinflammation , vol.9 , pp. 63
    • Gray, E.1    Ginty, M.2    Kemp, K.3    Scolding, N.4    Wilkins, A.5
  • 24
    • 33646177187 scopus 로고    scopus 로고
    • Baicalein is a potent in vitro inhibitor against both reticulocyte 15-human and platelet 12-human lipoxygenases
    • Deschamps JD, Kenyon VA, Holman TR. Baicalein is a potent in vitro inhibitor against both reticulocyte 15-human and platelet 12-human lipoxygenases. Bioorg Med Chem 2006; 14: 4295-4301
    • (2006) Bioorg Med Chem , vol.14 , pp. 4295-4301
    • Deschamps, J.D.1    Kenyon, V.A.2    Holman, T.R.3
  • 25
    • 33845442015 scopus 로고    scopus 로고
    • Baicalein LoEH and 12/15-lipoxygenase in the ischemic brain
    • van Leyen K, Kim HY, Lee SR, Jin G, Arai K, Baicalein LoEH. and 12/15-lipoxygenase in the ischemic brain. Stroke 2006; 37: 3014-3018
    • (2006) Stroke , vol.37 , pp. 3014-3018
    • Van Leyen, K.1    Kim, H.Y.2    Lee, S.R.3    Jin, G.4    Arai, K.5
  • 26
    • 0028067008 scopus 로고
    • The immunopathogenesis and regulation of T-cell-mediated demyelinating diseases
    • Miller SD, Karpus WJ. The immunopathogenesis and regulation of T-cell-mediated demyelinating diseases. Immunol Today 1994; 15: 356-361
    • (1994) Immunol Today , vol.15 , pp. 356-361
    • Miller, S.D.1    Karpus, W.J.2
  • 27
    • 84864603265 scopus 로고    scopus 로고
    • Clusters of activated microglia in normal-Appearing white matter show signs of innate immune activation
    • van Horssen J, Singh S, van der Pol S, Kipp M, Lim JL, Peferoen L et al. Clusters of activated microglia in normal-Appearing white matter show signs of innate immune activation. J Neuroinflammation 2012; 9: 156
    • (2012) J Neuroinflammation , vol.9 , pp. 156
    • Van Horssen, J.1    Singh, S.2    Van Der Pol, S.3    Kipp, M.4    Lim, J.L.5    Peferoen, L.6
  • 28
    • 84863088484 scopus 로고    scopus 로고
    • Neuroimmune crosstalk in the central nervous system and its significance for neurological diseases
    • Tian L, Ma L, Kaarela T, Li Z. Neuroimmune crosstalk in the central nervous system and its significance for neurological diseases. J Neuroinflammation 2012; 9: 155
    • (2012) J Neuroinflammation , vol.9 , pp. 155
    • Tian, L.1    Ma, L.2    Kaarela, T.3    Li, Z.4
  • 29
  • 30
    • 77952571744 scopus 로고    scopus 로고
    • Genetic ablation of steroid receptor coactivator-3 promotes PPAR-beta-mediated alternative activation of microglia in experimental autoimmune encephalomyelitis
    • Xiao Y, Xu J, Wang S, Mao C, Jin M, Ning G et al. Genetic ablation of steroid receptor coactivator-3 promotes PPAR-beta-mediated alternative activation of microglia in experimental autoimmune encephalomyelitis. Glia 2010; 58: 932-942
    • (2010) Glia , vol.58 , pp. 932-942
    • Xiao, Y.1    Xu, J.2    Wang, S.3    Mao, C.4    Jin, M.5    Ning, G.6
  • 31
    • 79952217413 scopus 로고    scopus 로고
    • Regulation of immune responses and autoimmune encephalomyelitis by PPARs
    • Yang Y, Lovett-Racke AE, Racke MK. Regulation of immune responses and autoimmune encephalomyelitis by PPARs. PPAR Res 2010; 2010: 104705
    • (2010) PPAR Res , vol.2010 , pp. 104705
    • Yang, Y.1    Lovett-Racke, A.E.2    Racke, M.K.3
  • 32
    • 70749160209 scopus 로고    scopus 로고
    • 12/15-Lipoxygenase inhibitor baicalein suppresses PPAR gamma expression and nuclear translocation induced by cerebral ischemia/reperfusion
    • Xu YW, Sun L, Liang H, Sun GM, Cheng Y. 12/15-Lipoxygenase inhibitor baicalein suppresses PPAR gamma expression and nuclear translocation induced by cerebral ischemia/reperfusion. Brain Res 2010; 1307: 149-157
    • (2010) Brain Res , vol.1307 , pp. 149-157
    • Xu, Y.W.1    Sun, L.2    Liang, H.3    Sun, G.M.4    Cheng, Y.5
  • 33
  • 34
    • 66449124004 scopus 로고    scopus 로고
    • Effects of the PPARbeta agonist GW501516 in an in vitro model of brain inflammation and antibody-Induced demyelination
    • Defaux A, Zurich MG, Braissant O, Honegger P, Monnet-Tschudi F. Effects of the PPARbeta agonist GW501516 in an in vitro model of brain inflammation and antibody-Induced demyelination. J Neuroinflammation 2009; 6: 15
    • (2009) J Neuroinflammation , vol.6 , pp. 15
    • Defaux, A.1    Zurich, M.G.2    Braissant, O.3    Honegger, P.4    Monnet-Tschudi, F.5
  • 35
    • 0030047806 scopus 로고    scopus 로고
    • Differential expression of peroxisome proliferator-Activated receptors (PPARs): Tissue distribution of PPAR-Alpha, beta, and -gamma in the adult rat
    • Braissant O, Foufelle F, Scotto C, Dauca M, Wahli W. Differential expression of peroxisome proliferator-Activated receptors (PPARs): Tissue distribution of PPAR-Alpha, -beta, and -gamma in the adult rat. Endocrinology 1996; 137: 354-366
    • (1996) Endocrinology , vol.137 , pp. 354-366
    • Braissant, O.1    Foufelle, F.2    Scotto, C.3    Dauca, M.4    Wahli, W.5
  • 36
    • 0034141545 scopus 로고    scopus 로고
    • The nuclear receptor PPAR gamma and immunoregulation: PPAR gamma mediates inhibition of helper T cell responses
    • Clark RB, Bishop-Bailey D, Estrada-Hernandez T, Hla T, Puddington L, Padula SJ. The nuclear receptor PPAR gamma and immunoregulation: PPAR gamma mediates inhibition of helper T cell responses. J Immunol 2000; 164: 1364-1371
    • (2000) J Immunol , vol.164 , pp. 1364-1371
    • Clark, R.B.1    Bishop-Bailey, D.2    Estrada-Hernandez, T.3    Hla, T.4    Puddington, L.5    Padula, S.J.6
  • 37
    • 0034660182 scopus 로고    scopus 로고
    • Peroxisome proliferator-Activated receptor-gamma activators inhibit IFN-gamma-Induced expression of the T cell-Active CXC chemokines IP-10, Mig, and I-TAC in human endothelial cells
    • Marx N, Mach F, Sauty A, Leung JH, Sarafi MN, Ransohoff RM et al. Peroxisome proliferator-Activated receptor-gamma activators inhibit IFN-gamma-Induced expression of the T cell-Active CXC chemokines IP-10, Mig, and I-TAC in human endothelial cells. J Immunol 2000; 164: 6503-6508
    • (2000) J Immunol , vol.164 , pp. 6503-6508
    • Marx, N.1    Mach, F.2    Sauty, A.3    Leung, J.H.4    Sarafi, M.N.5    Ransohoff, R.M.6
  • 38
    • 0036546185 scopus 로고    scopus 로고
    • Peroxisome proliferator-Activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation
    • Natarajan C, Bright JJ. Peroxisome proliferator-Activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation. Genes Immun 2002; 3: 59-70
    • (2002) Genes Immun , vol.3 , pp. 59-70
    • Natarajan, C.1    Bright, J.J.2
  • 39
    • 1542313910 scopus 로고    scopus 로고
    • Anti-Inflammatory and antiproliferative actions of PPAR-gamma agonists on T lymphocytes derived from MS patients
    • Schmidt S, Moric E, Schmidt M, Sastre M, Feinstein DL, Heneka MT. Anti-Inflammatory and antiproliferative actions of PPAR-gamma agonists on T lymphocytes derived from MS patients. J Leukoc Biol 2004; 75: 478-485
    • (2004) J Leukoc Biol , vol.75 , pp. 478-485
    • Schmidt, S.1    Moric, E.2    Schmidt, M.3    Sastre, M.4    Feinstein, D.L.5    Heneka, M.T.6
  • 40
    • 2142787409 scopus 로고    scopus 로고
    • Peroxisome proliferator-Activated receptor gamma (PPAR-gamma) activation in naive mouse T cells induces cell death
    • Harris SG, Phipps RP. Peroxisome proliferator-Activated receptor gamma (PPAR-gamma) activation in naive mouse T cells induces cell death. Ann N Y Acad Sci 2000; 905: 297-300
    • (2000) Ann N Y Acad Sci , vol.905 , pp. 297-300
    • Harris, S.G.1    Phipps, R.P.2
  • 41
    • 0037487144 scopus 로고    scopus 로고
    • Activation-Induced PPARgamma expression sensitizes primary human T cells toward apoptosis
    • Tautenhahn A, Brune B, von Knethen A. Activation-Induced PPARgamma expression sensitizes primary human T cells toward apoptosis. J Leukoc Biol 2003; 73: 665-672
    • (2003) J Leukoc Biol , vol.73 , pp. 665-672
    • Tautenhahn, A.1    Brune, B.2    Von Knethen, A.3
  • 42
    • 0032911057 scopus 로고    scopus 로고
    • The diversity of the lipoxygenase family Many sequence data but little information on biological significance
    • Kuhn H, Thiele BJ. The diversity of the lipoxygenase family. Many sequence data but little information on biological significance. FEBS Lett 1999; 449: 7-11
    • (1999) FEBS Lett , vol.449 , pp. 7-11
    • Kuhn, H.1    Thiele, B.J.2
  • 43
    • 0029844659 scopus 로고    scopus 로고
    • Disruption of 12/15-lipoxygenase expression in peritoneal macrophages. Enhanced utilization of the 5-lipoxygenase pathway and diminished oxidation of low density lipoprotein
    • Sun D, Funk CD. Disruption of 12/15-lipoxygenase expression in peritoneal macrophages. Enhanced utilization of the 5-lipoxygenase pathway and diminished oxidation of low density lipoprotein. J Biol Chem 1996; 271: 24055-24062
    • (1996) J Biol Chem , vol.271 , pp. 24055-24062
    • Sun, D.1    Funk, C.D.2
  • 44
    • 20844446795 scopus 로고    scopus 로고
    • Critical role of macrophage 12/15-lipoxygenase for atherosclerosis in apolipoprotein E-deficient mice
    • Huo Y, Zhao L, Hyman MC, Shashkin P, Harry BL, Burcin T et al. Critical role of macrophage 12/15-lipoxygenase for atherosclerosis in apolipoprotein E-deficient mice. Circulation 2004; 110: 2024-2031
    • (2004) Circulation , vol.110 , pp. 2024-2031
    • Huo, Y.1    Zhao, L.2    Hyman, M.C.3    Shashkin, P.4    Harry, B.L.5    Burcin, T.6
  • 45
    • 27644571486 scopus 로고    scopus 로고
    • 12/15-Lipoxygenase regulates intercellular adhesion molecule-1 expression and monocyte adhesion to endothelium through activation of RhoA and nuclear factor-kappaB
    • Bolick DT, Orr AW, Whetzel A, Srinivasan S, Hatley ME, Schwartz MA et al. 12/15-Lipoxygenase regulates intercellular adhesion molecule-1 expression and monocyte adhesion to endothelium through activation of RhoA and nuclear factor-kappaB. Arterioscler Thromb Vasc Biol 2005; 25: 2301-2307
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 2301-2307
    • Bolick, D.T.1    Orr, A.W.2    Whetzel, A.3    Srinivasan, S.4    Hatley, M.E.5    Schwartz, M.A.6
  • 46
    • 68949116297 scopus 로고    scopus 로고
    • Dual 12/15-And 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice
    • Poeckel D, Zemski Berry KA, Murphy RC, Funk CD. Dual 12/15-And 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice. J Biol Chem 2009; 284: 21077-21089
    • (2009) J Biol Chem , vol.284 , pp. 21077-21089
    • Poeckel, D.1    Zemski Berry, K.A.2    Murphy, R.C.3    Funk, C.D.4
  • 47
    • 0028874383 scopus 로고
    • Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat
    • Tokuyama Y, Sturis J, DePaoli AM, Takeda J, Stoffel M, Tang J et al. Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat. Diabetes 1995; 44: 1447-1457
    • (1995) Diabetes , vol.44 , pp. 1447-1457
    • Tokuyama, Y.1    Sturis, J.2    DePaoli, A.M.3    Takeda, J.4    Stoffel, M.5    Tang, J.6
  • 48
    • 0032723345 scopus 로고    scopus 로고
    • Resistance to type 1 diabetes induction in 12-lipoxygenase knockout mice
    • Bleich D, Chen S, Zipser B, Sun D, Funk CD, Nadler JL. Resistance to type 1 diabetes induction in 12-lipoxygenase knockout mice. J Clin Invest 1999; 103: 1431-1436
    • (1999) J Clin Invest , vol.103 , pp. 1431-1436
    • Bleich, D.1    Chen, S.2    Zipser, B.3    Sun, D.4    Funk, C.D.5    Nadler, J.L.6
  • 49
    • 84859417816 scopus 로고    scopus 로고
    • Macrophage 12/15 lipoxygenase expression increases plasma and hepatic lipid levels and exacerbates atherosclerosis
    • Rong S, Cao Q, Liu M, Seo J, Jia L, Boudyguina E et al. Macrophage 12/15 lipoxygenase expression increases plasma and hepatic lipid levels and exacerbates atherosclerosis. J Lipid Res 2012; 53: 686-695
    • (2012) J Lipid Res , vol.53 , pp. 686-695
    • Rong, S.1    Cao, Q.2    Liu, M.3    Seo, J.4    Jia, L.5    Boudyguina, E.6
  • 51
    • 42049114647 scopus 로고    scopus 로고
    • 5-Lipoxygenase gene disruption reduces amyloid-beta pathology in a mouse model of Alzheimer's disease
    • Firuzi O, Zhuo J, Chinnici CM, Wisniewski T, Pratico D. 5-Lipoxygenase gene disruption reduces amyloid-beta pathology in a mouse model of Alzheimer's disease. FASEB J 2008; 22: 1169-1178
    • (2008) FASEB J , vol.22 , pp. 1169-1178
    • Firuzi, O.1    Zhuo, J.2    Chinnici, C.M.3    Wisniewski, T.4    Pratico, D.5
  • 52
    • 77952150495 scopus 로고    scopus 로고
    • Immunopharmacological role of the leukotriene receptor antagonists and inhibitors of leukotrienes generating enzymes in multiple sclerosis
    • Mirshafiey A, Jadidi-Niaragh F. Immunopharmacological role of the leukotriene receptor antagonists and inhibitors of leukotrienes generating enzymes in multiple sclerosis. Immunopharmacol Immunotoxicol 2010; 32: 219-227
    • (2010) Immunopharmacol Immunotoxicol , vol.32 , pp. 219-227
    • Mirshafiey, A.1    Jadidi-Niaragh, F.2
  • 53
    • 25844473319 scopus 로고    scopus 로고
    • Protective effects of a peroxisome proliferator-Activated receptor-beta/delta agonist in experimental autoimmune encephalomyelitis
    • Polak PE, Kalinin S, Dello Russo C, Gavrilyuk V, Sharp A, Peters JM et al. Protective effects of a peroxisome proliferator-Activated receptor-beta/delta agonist in experimental autoimmune encephalomyelitis. J Neuroimmunology 2005; 168: 65-75
    • (2005) J Neuroimmunology , vol.168 , pp. 65-75
    • Polak, P.E.1    Kalinin, S.2    Dello Russo, C.3    Gavrilyuk, V.4    Sharp, A.5    Peters, J.M.6
  • 54
    • 77955343205 scopus 로고    scopus 로고
    • Peroxisome proliferatoractivated receptor delta limits the expansion of pathogenic Th cells during central nervous system autoimmunity
    • Dunn SE, Bhat R, Straus DS, Sobel RA, Axtell R, Johnson A et al. Peroxisome proliferatoractivated receptor delta limits the expansion of pathogenic Th cells during central nervous system autoimmunity. J Exp Med 2010; 207: 1599-1608
    • (2010) J Exp Med , vol.207 , pp. 1599-1608
    • Dunn, S.E.1    Bhat, R.2    Straus, D.S.3    Sobel, R.A.4    Axtell, R.5    Johnson, A.6
  • 55
    • 12244308528 scopus 로고    scopus 로고
    • The effects of the cyclosporin A, a P-glycoprotein inhibitor, on the pharmacokinetics of baicalein in the rat: A microdialysis study
    • Tsai TH, Liu SC, Tsai PL, Ho LK, Shum AY, Chen CF. The effects of the cyclosporin A, a P-glycoprotein inhibitor, on the pharmacokinetics of baicalein in the rat: A microdialysis study. Br J Pharmacol 2002; 137: 1314-1320
    • (2002) Br J Pharmacol , vol.137 , pp. 1314-1320
    • Tsai, T.H.1    Liu, S.C.2    Tsai, P.L.3    Ho, L.K.4    Shum, A.Y.5    Chen, C.F.6
  • 56
    • 0037168869 scopus 로고    scopus 로고
    • PPARalpha and PPARdelta activators inhibit cytokine-Induced nuclear translocation of NFkappaB and expression of VCAM-1 in EAhy926 endothelial cells
    • Rival Y, Beneteau N, Taillandier T, Pezet M, Dupont-Passelaigue E, Patoiseau JF et al. PPARalpha and PPARdelta activators inhibit cytokine-Induced nuclear translocation of NFkappaB and expression of VCAM-1 in EAhy926 endothelial cells. Eur J Pharmacol 2002; 435: 143-151
    • (2002) Eur J Pharmacol , vol.435 , pp. 143-151
    • Rival, Y.1    Beneteau, N.2    Taillandier, T.3    Pezet, M.4    Dupont-Passelaigue, E.5    Patoiseau, J.F.6
  • 57
    • 57649155050 scopus 로고    scopus 로고
    • Inflammatory pathways are activated during cardiomyocyte hypertrophy and attenuated by peroxisome proliferator-Activated receptors PPARalpha and PPARdelta
    • Smeets PJ, Teunissen BE, Planavila A, de Vogel-van den Bosch H, Willemsen PH, van der Vusse GJ et al. Inflammatory pathways are activated during cardiomyocyte hypertrophy and attenuated by peroxisome proliferator-Activated receptors PPARalpha and PPARdelta. J Biol Chem 2008; 283: 29109-29118
    • (2008) J Biol Chem , vol.283 , pp. 29109-29118
    • Smeets, P.J.1    Teunissen, B.E.2    Planavila, A.3    De Vogel-Van Den Bosch, H.4    Willemsen, P.H.5    Van Der Vusse, G.J.6
  • 58
    • 50949105881 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-Activated receptor beta/delta inhibits lipopolysaccharide-Induced cytokine production in adipocytes by lowering nuclear factor-kappaB activity via extracellular signal-related kinase 1/2
    • Rodriguez-Calvo R, Serrano L, Coll T, Moullan N, Sanchez RM, Merlos M et al. Activation of peroxisome proliferator-Activated receptor beta/delta inhibits lipopolysaccharide-Induced cytokine production in adipocytes by lowering nuclear factor-kappaB activity via extracellular signal-related kinase 1/2. Diabetes 2008; 57: 2149-2157
    • (2008) Diabetes , vol.57 , pp. 2149-2157
    • Rodriguez-Calvo, R.1    Serrano, L.2    Coll, T.3    Moullan, N.4    Sanchez, R.M.5    Merlos, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.