메뉴 건너뛰기




Volumn 13, Issue 2, 2013, Pages 237-255

Palmitoylethanolamide is a new possible pharmacological treatment for the inflammation associated with Trauma

Author keywords

Acylethanolamines; Inflammation; PPAR alpha; SCI

Indexed keywords

ANANDAMIDE; DEXAMETHASONE; DICLOFENAC; FATTY ACID AMIDASE INHIBITOR; HYDROCORTISONE; MONOCYTE CHEMOTACTIC PROTEIN 2; N METHYL DEXTRO ASPARTIC ACID; OLEAMIDE; PALMIDROL; PLACEBO; PREGABALIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 84876868085     PISSN: 13895575     EISSN: 18755607     Source Type: Journal    
DOI: 10.2174/138955713804805184     Document Type: Article
Times cited : (59)

References (169)
  • 2
    • 33846378110 scopus 로고    scopus 로고
    • Palmitoylethanolamide, endocannabinoids and related cannabimimetic compounds in protection against tissue inflammation and pain: Potential use in companion animals
    • Re, G.; Barbero, R.; Miolo, A.; Di Marzo, V. Palmitoylethanolamide, endocannabinoids and related cannabimimetic compounds in protection against tissue inflammation and pain: Potential use in companion animals. Vet. J., 2007, 173(1), 23-32.
    • (2007) Vet. J , vol.173 , Issue.1 , pp. 23-32
    • Re, G.1    Barbero, R.2    Miolo, A.3    Di Marzo, V.4
  • 3
    • 3242703446 scopus 로고    scopus 로고
    • Occurrence, metabolism, and prospective functions of N-acylethanolamines in plants
    • Chapman, K.D. Occurrence, metabolism, and prospective functions of N-acylethanolamines in plants. Prog. Lipid Res., 2004, 43(4), 302-327.
    • (2004) Prog. Lipid Res , vol.43 , Issue.4 , pp. 302-327
    • Chapman, K.D.1
  • 4
    • 0036019421 scopus 로고    scopus 로고
    • Cannabinoid receptor-inactive Nacylethanolamines and other fatty acid amides: Metabolism and function
    • Schmid, H.H.; Berdyshev, E.V. Cannabinoid receptor-inactive Nacylethanolamines and other fatty acid amides: metabolism and function. Prostaglandins Leukot. Essent. Fatty Acids, 2002, 66(2-3), 363-376.
    • (2002) Prostaglandins Leukot. Essent. Fatty Acids , vol.66 , Issue.2-3 , pp. 363-376
    • Schmid, H.H.1    Berdyshev, E.V.2
  • 5
    • 84891727054 scopus 로고    scopus 로고
    • Anandamide and Other Acylethanolamides. Chapter 5
    • Tettamanti G and Goracci G (eds.), Neural Lipids, 3rd edition, Springer
    • Petrosino, S.; Di Marzo, V. Anandamide and Other Acylethanolamides. Chapter 5 In: Tettamanti G and Goracci G (eds.), Handbook of neurochemistry and molecular neurobiology. Neural Lipids, 3rd edition, Springer, 2009 pp.75-98.
    • (2009) Handbook of Neurochemistry and Molecular Neurobiology , pp. 75-98
    • Petrosino, S.1    Di Marzo, V.2
  • 6
    • 77953291080 scopus 로고    scopus 로고
    • N-palmitoyl-ethanolamine: Biochemistry and new therapeutic opportunities
    • Petrosino, S.; Iuvone, T.; Di Marzo, V. N-palmitoyl-ethanolamine: Biochemistry and new therapeutic opportunities. Biochimie, 2010, 92(6), 724-727.
    • (2010) Biochimie , vol.92 , Issue.6 , pp. 724-727
    • Petrosino, S.1    Iuvone, T.2    Di Marzo, V.3
  • 7
    • 77956393864 scopus 로고    scopus 로고
    • N-acylethanolamine metabolism with special reference to 4 N-acylethanolamine-hydrolyzing acid amidase (NAAA)
    • Ueda, N.; Tsuboi, K.; Uyama, T. N-acylethanolamine metabolism with special reference to 4 N-acylethanolamine-hydrolyzing acid amidase (NAAA). Prog. Lipid Res., 2010, 49(4), 299-315.
    • (2010) Prog. Lipid Res , vol.49 , Issue.4 , pp. 299-315
    • Ueda, N.1    Tsuboi, K.2    Uyama, T.3
  • 8
    • 0031031557 scopus 로고    scopus 로고
    • Biosynthesis, uptake, and degradation of anandamide and palmitoylethanolamide in leukocytes
    • Bisogno, T.; Maurelli, S.; Melck, D.; De Petrocellis, L.; Di Marzo, V. Biosynthesis, uptake, and degradation of anandamide and palmitoylethanolamide in leukocytes. J. Biol. Chem., 1997, 272(6), 3315-3323.
    • (1997) J. Biol. Chem , vol.272 , Issue.6 , pp. 3315-3323
    • Bisogno, T.1    Maurelli, S.2    Melck, D.3    de Petrocellis, L.4    Di Marzo, V.5
  • 9
    • 0035043018 scopus 로고    scopus 로고
    • Characterization of palmitoylethanolamide transport in mouse Neuro-2a neuroblastoma and rat RBL-2H3 basophilic leukaemia cells: Comparison with anandamide
    • Jacobsson, S.O.; Fowler, C.J. Characterization of palmitoylethanolamide transport in mouse Neuro-2a neuroblastoma and rat RBL-2H3 basophilic leukaemia cells: comparison with anandamide. Br. J. Pharmacol., 2001, 132(8), 1743-17454.
    • (2001) Br. J. Pharmacol , vol.132 , Issue.8 , pp. 1743-17454
    • Jacobsson, S.O.1    Fowler, C.J.2
  • 10
    • 0032784084 scopus 로고    scopus 로고
    • Cannabimimetic fatty acid derivatives: The anandamide family and other endocannabinoids
    • Di Marzo, V.; Bisogno, T.; De Petrocellis, L.; Melck, D.; Martin, B.R. Cannabimimetic fatty acid derivatives: the anandamide family and other endocannabinoids. Curr. Med. Chem., 1999, 6(8), 721-744.
    • (1999) Curr. Med. Chem , vol.6 , Issue.8 , pp. 721-744
    • Di Marzo, V.1    Bisogno, T.2    de Petrocellis, L.3    Melck, D.4    Martin, B.R.5
  • 11
    • 0028906566 scopus 로고
    • Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide
    • Facci, L.; Dal Toso, R.; Romanello, S.; Buriani, A.; Skaper, S.D.; Leon, A. Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide. Proc. Natl. Acad. Sci., 1995, 92(8), 3376-3380.
    • (1995) Proc. Natl. Acad. Sci , vol.92 , Issue.8 , pp. 3376-3380
    • Facci, L.1    Dal Toso, R.2    Romanello, S.3    Buriani, A.4    Skaper, S.D.5    Leon, A.6
  • 12
    • 0036216311 scopus 로고    scopus 로고
    • The palmitoylethanolamide family: A new class of anti-inflammatory agents
    • Lambert, D.M.; Vandevoorde, S.; Jonsson, K.O.; Fowler, C.J. The palmitoylethanolamide family: a new class of anti-inflammatory agents? Curr. Med. Chem., 2002, 9(6), 663-674.
    • (2002) Curr. Med. Chem , vol.9 , Issue.6 , pp. 663-674
    • Lambert, D.M.1    Vandevoorde, S.2    Jonsson, K.O.3    Fowler, C.J.4
  • 13
    • 0032766027 scopus 로고    scopus 로고
    • The palmitoylethanolamide and oleamide enigmas: Are these two fatty acid amides cannabimimetic
    • Lambert, D.M.; Di Marzo, V. The palmitoylethanolamide and oleamide enigmas: are these two fatty acid amides cannabimimetic? Curr. Med. Chem., 1999, 6(8), 757-773.
    • (1999) Curr. Med. Chem , vol.6 , Issue.8 , pp. 757-773
    • Lambert, D.M.1    Di Marzo, V.2
  • 14
    • 0030425575 scopus 로고    scopus 로고
    • Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): Identification of cannabinoid receptor subtype selective ligands
    • Showalter, V.M.; Compton, D.R.; Martin, B.R.; Abood, M.E. Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): identification of cannabinoid receptor subtype selective ligands. J. Pharmacol. Exp. Ther., 1996, 278(3), 989-999.
    • (1996) J. Pharmacol. Exp. Ther , vol.278 , Issue.3 , pp. 989-999
    • Showalter, V.M.1    Compton, D.R.2    Martin, B.R.3    Abood, M.E.4
  • 15
    • 0034614374 scopus 로고    scopus 로고
    • Evidence that 2-arachidonoylglycerol but not N-palmitoylethanolamine or anandamide is the physiological ligand for the cannabinoid CB2 receptor. Comparison of the agonistic activities of various cannabinoid receptor ligands in HL-60 cells
    • Sugiura, T.; Kondo, S.; Kishimoto, S.; Miyashita, T.; Nakane, S.; Kodaka, T.; Suhara, Y.; Takayama, H.; Waku, K. Evidence that 2-arachidonoylglycerol but not N-palmitoylethanolamine or anandamide is the physiological ligand for the cannabinoid CB2 receptor. Comparison of the agonistic activities of various cannabinoid receptor ligands in HL-60 cells. J. Biol. Chem., 2000, 275(1), 605-612.
    • (2000) J. Biol. Chem , vol.275 , Issue.1 , pp. 605-612
    • Sugiura, T.1    Kondo, S.2    Kishimoto, S.3    Miyashita, T.4    Nakane, S.5    Kodaka, T.6    Suhara, Y.7    Takayama, H.8    Waku, K.9
  • 16
    • 0031776783 scopus 로고    scopus 로고
    • The antihyperalgesic actions of the cannabinoid anandamide and the putative CB2 receptor agonist palmitoylethanolamide in visceral and somatic inflammatory pain
    • Jaggar, S.I.; Hasnie, F.S.; Sellaturay, S.; Rice, A.S. The antihyperalgesic actions of the cannabinoid anandamide and the putative CB2 receptor agonist palmitoylethanolamide in visceral and somatic inflammatory pain. Pain, 1998, 76(1-2), 189-199.
    • (1998) Pain , vol.76 , Issue.1-2 , pp. 189-199
    • Jaggar, S.I.1    Hasnie, F.S.2    Sellaturay, S.3    Rice, A.S.4
  • 17
    • 0032537734 scopus 로고    scopus 로고
    • Control of pain initiation by endogenous cannabinoids
    • Calignano, A.; La Rana, G.; Giuffrida, A.; Piomelli, D. Control of pain initiation by endogenous cannabinoids. Nature, 1998, 394 (6690), 277-281.
    • (1998) Nature , vol.394 , Issue.6690 , pp. 277-281
    • Calignano, A.1    la Rana, G.2    Giuffrida, A.3    Piomelli, D.4
  • 18
    • 0036157693 scopus 로고    scopus 로고
    • Antiinflammatory action of endocannabinoid palmitoylethanolamide and the synthetic cannabinoid nabilone in a model of acute inflammation in the rat
    • Conti, S.; Costa, B.; Colleoni, M.; Parolaro, D.; Giagnoni, G. Antiinflammatory action of endocannabinoid palmitoylethanolamide and the synthetic cannabinoid nabilone in a model of acute inflammation in the rat. Br. J. Pharmacol., 2002, 135(1), 181-7.
    • (2002) Br. J. Pharmacol , vol.135 , Issue.1 , pp. 181-187
    • Conti, S.1    Costa, B.2    Colleoni, M.3    Parolaro, D.4    Giagnoni, G.5
  • 20
    • 77950630872 scopus 로고    scopus 로고
    • GPR55: Current Knowledge and Future Perspectives of a Purported Type-3 Cannabinoid Receptor
    • Moriconi, A.; Cerbara, I.; Maccarrone, M.; Topai, A. GPR55: Current Knowledge and Future Perspectives of a Purported Type-3 Cannabinoid Receptor. Curr. Med. Chem., 2010, 17(14), 1411-1429.
    • (2010) Curr. Med. Chem , vol.17 , Issue.14 , pp. 1411-1429
    • Moriconi, A.1    Cerbara, I.2    Maccarrone, M.3    Topai, A.4
  • 21
    • 11244328917 scopus 로고    scopus 로고
    • The nuclear receptor peroxisome proliferatoractivated receptor-alpha mediates the anti-inflammatory actions of palmitoylethanolamide
    • LoVerme, J.; Fu, J.; Astarita, G.; La Rana, G.; Russo, R.; Calignano, A.; Piomelli, D. The nuclear receptor peroxisome proliferatoractivated receptor-alpha mediates the anti-inflammatory actions of palmitoylethanolamide. Mol. Pharmacol., 2005, 67(1), 15-19.
    • (2005) Mol. Pharmacol , vol.67 , Issue.1 , pp. 15-19
    • Loverme, J.1    Fu, J.2    Astarita, G.3    la Rana, G.4    Russo, R.5    Calignano, A.6    Piomelli, D.7
  • 24
    • 71649099454 scopus 로고    scopus 로고
    • Effects of palmitoylethanolamide on immunologically induced histamine, PGD2 and TNF release from canine skin mast cells
    • Cerrato, S.; Brazis, P.; Miolo, A.; della Valle, F.; Puigdemont, A. Effects of palmitoylethanolamide on immunologically induced histamine, PGD2 and TNF release from canine skin mast cells. Vet. Immunol. Immunopathol., 2010, 133(1), 9-15.
    • (2010) Vet. Immunol. Immunopathol , vol.133 , Issue.1 , pp. 9-15
    • Cerrato, S.1    Brazis, P.2    Miolo, A.3    della Valle, F.4    Puigdemont, A.5
  • 26
    • 0029870716 scopus 로고    scopus 로고
    • The ALIAmide palmitoylethanolamide and cannabinoids, but not anandamide, are protective in a delayed postglutamate paradigm of excitotoxic death in cerebellar granule neurons
    • Skaper, S.D.; Buriani, A.; Dal Toso, R.; Petrelli, L.; Romanello, S.; Facci, L.; Leon, A. The ALIAmide palmitoylethanolamide and cannabinoids, but not anandamide, are protective in a delayed postglutamate paradigm of excitotoxic death in cerebellar granule neurons. Proc. Natl. Acad. Sci. U S A., 1996, 93(9), 3984-3989.
    • (1996) Proc. Natl. Acad. Sci. U S A , vol.93 , Issue.9 , pp. 3984-3989
    • Skaper, S.D.1    Buriani, A.2    Dal Toso, R.3    Petrelli, L.4    Romanello, S.5    Facci, L.6    Leon, A.7
  • 27
    • 0036797445 scopus 로고    scopus 로고
    • Therapeutic effect of the endogenous fatty acid amide, palmitoylethanolamide, in rat acute inflammation: Inhibition of nitric oxide and cyclo-oxygenase systems
    • Costa, B.; Conti, S.; Giagnoni, G.; Colleoni, M. Therapeutic effect of the endogenous fatty acid amide, palmitoylethanolamide, in rat acute inflammation: inhibition of nitric oxide and cyclo-oxygenase systems. Br. J. Pharmacol., 2002, 137(4), 413-420.
    • (2002) Br. J. Pharmacol , vol.137 , Issue.4 , pp. 413-420
    • Costa, B.1    Conti, S.2    Giagnoni, G.3    Colleoni, M.4
  • 28
    • 84857232040 scopus 로고    scopus 로고
    • Effects of palmitoylethanolamide on the cutaneous allergic inflammatory response in Ascaris hypersensitive Beagle dogs
    • Cerrato, S.; Brazis, P.; della Valle, M.F.; Miolo, A.; Petrosino, S.; Di Marzo, V.; Puigdemont, A. Effects of palmitoylethanolamide on the cutaneous allergic inflammatory response in Ascaris hypersensitive Beagle dogs. Vet. J., 2012, 191(3), 377-382.
    • (2012) Vet. J , vol.191 , Issue.3 , pp. 377-382
    • Cerrato, S.1    Brazis, P.2    della Valle, M.F.3    Miolo, A.4    Petrosino, S.5    Di Marzo, V.6    Puigdemont, A.7
  • 30
    • 33947522320 scopus 로고    scopus 로고
    • Effects of the fatty acid amide hydrolase inhibitor URB597 on the sleep-wake cycle, c-Fos expression and dopamine levels of the rat
    • Murillo-Rodríguez, E.; Vázquez, E.; Millán-Aldaco, D.; PalomeroRivero, M.; Drucker-Colin, R. Effects of the fatty acid amide hydrolase inhibitor URB597 on the sleep-wake cycle, c-Fos expression and dopamine levels of the rat. Eur. J. Pharmacol., 2007, 562(1-2), 82-91.
    • (2007) Eur. J. Pharmacol , vol.562 , Issue.1-2 , pp. 82-91
    • Murillo-Rodríguez, E.1    Vázquez, E.2    Millán-Aldaco, D.3    Palomerorivero, M.4    Drucker-Colin, R.5
  • 33
    • 54549098992 scopus 로고    scopus 로고
    • Endocannabinoids mediate neuroprotection after transient focal cerebral ischemia
    • Schomacher, M.; Müller, H.D.; Schwab, S.; Sommer, C.; Schäbitz, W.R. Endocannabinoids mediate neuroprotection after transient focal cerebral ischemia. Brain Res., 2008, 1240, 213-220.
    • (2008) Brain Res , vol.1240 , pp. 213-220
    • Schomacher, M.1    Müller, H.D.2    Schwab, S.3    Sommer, C.4    Schäbitz, W.R.5
  • 34
    • 0035257673 scopus 로고    scopus 로고
    • Clinical and histological evaluation of an analogue of palmitoylethanolamide, PLR 120 (comicronized Palmidrol INN) in cats with eosinophilic granuloma and eosinophilic plaque: A pilot study
    • Scarampella, F.; Abramo, F.; Noli, C. Clinical and histological evaluation of an analogue of palmitoylethanolamide, PLR 120 (comicronized Palmidrol INN) in cats with eosinophilic granuloma and eosinophilic plaque: a pilot study. Vet. Dermatol., 2001, 12(1), 29-39.
    • (2001) Vet. Dermatol , vol.12 , Issue.1 , pp. 29-39
    • Scarampella, F.1    Abramo, F.2    Noli, C.3
  • 35
    • 77953103422 scopus 로고    scopus 로고
    • La palmitoiletanolamida (Normast®) en el dolor neuropático crónico por lumbociatalgia de tipo compresivo: Estudio clínico multicéntrico
    • Guida, G.; de Martino, M.; de Fabiani, A.; Cantieri, L.; Alexandre, A.; Vassallo, G.M.; Rogai, M.; Lanaia, F.; Petrosino, S. La palmitoiletanolamida (Normast®) en el dolor neuropático crónico por lumbociatalgia de tipo compresivo: estudio clínico multicéntrico. Dolor, 2010, 25, 35-42.
    • (2010) Dolor , vol.25 , pp. 35-42
    • Guida, G.1    de Martino, M.2    de Fabiani, A.3    Cantieri, L.4    Alexandre, A.5    Vassallo, G.M.6    Rogai, M.7    Lanaia, F.8    Petrosino, S.9
  • 36
    • 79952554794 scopus 로고    scopus 로고
    • Reducción del consumo de antiinflamatorios y analgésicos en el tratamiento del dolor neuropático crónico en pacientes afectados por lumbociatalgia de tipo compresivo y en tratamiento con Normast® 300 mg
    • Canteri, L.; Petrosino, S.; Guida, G. Reducción del consumo de antiinflamatorios y analgésicos en el tratamiento del dolor neuropático crónico en pacientes afectados por lumbociatalgia de tipo compresivo y en tratamiento con Normast® 300 mg. Dolor, 2010, 25(4), 227-234.
    • (2010) Dolor , vol.25 , Issue.4 , pp. 227-234
    • Canteri, L.1    Petrosino, S.2    Guida, G.3
  • 37
    • 79957659495 scopus 로고    scopus 로고
    • Use of the palmitoylethanolamide in the entrapment neuropathy of the median in the wrist
    • Conigliaro, R.; Drago, V.; Foster, P.S.; Schievano, C.; Di Marzo, V. Use of the palmitoylethanolamide in the entrapment neuropathy of the median in the wrist. Minerva Med., 2011, 102(2), 141-147.
    • (2011) Minerva Med , vol.102 , Issue.2 , pp. 141-147
    • Conigliaro, R.1    Drago, V.2    Foster, P.S.3    Schievano, C.4    Di Marzo, V.5
  • 38
    • 84859555026 scopus 로고    scopus 로고
    • Associazione tra pregabalin e palmitoiletanolamide per il trattamento del dolore neuropatico
    • Desio, P. Associazione tra pregabalin e palmitoiletanolamide per il trattamento del dolore neuropatico. Pathos, 2010, 17(4).
    • (2010) Pathos , vol.17 , Issue.4
    • Desio, P.1
  • 39
    • 37749016059 scopus 로고    scopus 로고
    • Adjuvant treatment of atopic eczema: Assessment of an emollient containing N-palmitoylethanolamine (ATOPA study)
    • Eberlein, B.; Eicke, C.; Reinhardt, H.W.; Ring, J. Adjuvant treatment of atopic eczema: assessment of an emollient containing N-palmitoylethanolamine (ATOPA study). J. Eur. Acad. Dermatol. Venereol., 2008, 22(1), 73-82.
    • (2008) J. Eur. Acad. Dermatol. Venereol , vol.22 , Issue.1 , pp. 73-82
    • Eberlein, B.1    Eicke, C.2    Reinhardt, H.W.3    Ring, J.4
  • 40
    • 0000434849 scopus 로고
    • The effect of egg yolk in diets on anaphylactic arthritis (passive Arthus phenomenon) in the guinea pig
    • Coburn, A.F.; Graham, C.E.; Haninger, J. The effect of egg yolk in diets on anaphylactic arthritis (passive Arthus phenomenon) in the guinea pig. J. Exp. Med., 1954, 100(5), 425-435.
    • (1954) J. Exp. Med , vol.100 , Issue.5 , pp. 425-435
    • Coburn, A.F.1    Graham, C.E.2    Haninger, J.3
  • 41
    • 0000947743 scopus 로고
    • Factor in arachis oil depressing sensitivity to tuberculin in B.C.G.-infected guineapigs
    • Long, D.A.; Martin, A.J. Factor in arachis oil depressing sensitivity to tuberculin in B.C.G.-infected guineapigs. Lancet, 1956, 270 (6921), 464-6.
    • (1956) Lancet , vol.270 , Issue.6921 , pp. 464-466
    • Long, D.A.1    Martin, A.J.2
  • 42
    • 0001162640 scopus 로고
    • The identification of N-(2-hydroxyethyl)-palmitamide as a naturally occuring anti-inflammatory agent
    • Kuehl, F.A.Jr.; Jacob, T.A.; Ganley, O.H.; Ormond, R.E.; Meisinger, M.A.P. The identification of N-(2-hydroxyethyl)-palmitamide as a naturally occuring anti-inflammatory agent. J. Am. Chem. Soc., 1957, 79(19), 5577-5578.
    • (1957) J. Am. Chem. Soc , vol.79 , Issue.19 , pp. 5577-5578
    • Kuehl Jr., F.A.1    Jacob, T.A.2    Ganley, O.H.3    Ormond, R.E.4    Meisinger, M.A.P.5
  • 43
    • 0011433814 scopus 로고
    • Anti-inflammatory activity on compounds obtained from egg yolk, peanut oil, and soybean lecithin
    • Ganley, O.H.; Graessle, O.E.; Robinson, H.J. Anti-inflammatory activity on compounds obtained from egg yolk, peanut oil, and soybean lecithin. J. Lab. Clin. Med., 1958, 51(5), 709-714.
    • (1958) J. Lab. Clin. Med , vol.51 , Issue.5 , pp. 709-714
    • Ganley, O.H.1    Graessle, O.E.2    Robinson, H.J.3
  • 44
    • 0011434564 scopus 로고
    • Antianaphylactic and antiserotonin activity of a compound obtained from eggyolk, peanut oil and soybean lecithin
    • Ganley, O.H.; Robinson, H.J. Antianaphylactic and antiserotonin activity of a compound obtained from eggyolk, peanut oil and soybean lecithin. J. Allergy, 1959, 30, 415-9.
    • (1959) J. Allergy , vol.30 , pp. 415-419
    • Ganley, O.H.1    Robinson, H.J.2
  • 45
    • 0014416308 scopus 로고
    • Attività di alcuni derivati della palmitoiletanolamide sull'edema da carragenina nella zampa di ratto
    • Benvenuti, F.; Lattanzi, F.; De Gori, A.; Tarli, P. Attività di alcuni derivati della palmitoiletanolamide sull'edema da carragenina nella zampa di ratto. Boll. Soc. Ital. Biol. Sper., 1968, 44(9), 809-813.
    • (1968) Boll. Soc. Ital. Biol. Sper , vol.44 , Issue.9 , pp. 809-813
    • Benvenuti, F.1    Lattanzi, F.2    de Gori, A.3    Tarli, P.4
  • 46
    • 0015186245 scopus 로고
    • Anti-inflammatory properties of N(2-hydroxyethyl) palmitamide
    • Perlik, F.; Raskova, H.; Elis, J. Anti-inflammatory properties of N(2-hydroxyethyl) palmitamide. Acta Physiol. Acad. Sci. Hung, 1971, 39(4), 395-400.
    • (1971) Acta Physiol. Acad. Sci. Hung , vol.39 , Issue.4 , pp. 395-400
    • Perlik, F.1    Raskova, H.2    Elis, J.3
  • 47
    • 0016261404 scopus 로고
    • Prophylactic efficacy of N-2-hydroxyethyl palmitamide (impulsin) in acute respiratory tract infections
    • Masek, K.; Perlik, F.; Klima, J.; Kahlich, R. Prophylactic efficacy of N-2-hydroxyethyl palmitamide (impulsin) in acute respiratory tract infections. Eur. J. Clin. Pharmacol., 1974, 7(6), 415-419.
    • (1974) Eur. J. Clin. Pharmacol , vol.7 , Issue.6 , pp. 415-419
    • Masek, K.1    Perlik, F.2    Klima, J.3    Kahlich, R.4
  • 48
    • 0018308141 scopus 로고
    • Studies on prophylactic efficacy of N-2-hydroxyethyl palmitamide (Impulsin) in acute respiratory infections. Serologically controlled field trials
    • Kahlich, R.; Klima, J.; Cihla, F.; Frankova, V.; Masek, K.; Rosicky, M.; Matousek, F.; Bruthans, J. Studies on prophylactic efficacy of N-2-hydroxyethyl palmitamide (Impulsin) in acute respiratory infections. Serologically controlled field trials. J. Hyg. Epidemiol. Microbiol. Immunol., 1979, 23(1), 11-24.
    • (1979) J. Hyg. Epidemiol. Microbiol. Immunol , vol.23 , Issue.1 , pp. 11-24
    • Kahlich, R.1    Klima, J.2    Cihla, F.3    Frankova, V.4    Masek, K.5    Rosicky, M.6    Matousek, F.7    Bruthans, J.8
  • 49
    • 0027313392 scopus 로고
    • A proposed autacoid mechanism controlling mastocyte behaviour
    • 39 Spec No, C145-147
    • Aloe, L.; Leon, A.; Levi-Montalcini, R. A proposed autacoid mechanism controlling mastocyte behaviour. Agents Actions, 1993, 39 Spec No, C145-147
    • (1993) Agents Actions
    • Aloe, L.1    Leon, A.2    Levi-Montalcini, R.3
  • 50
    • 45749155263 scopus 로고    scopus 로고
    • Nerve-mast cell and smooth muscle-mast cell interaction mediated by cell adhesion molecule-1, CADM1
    • Ito, A.; Hagiyama, M.; Oonuma, J. Nerve-mast cell and smooth muscle-mast cell interaction mediated by cell adhesion molecule-1, CADM1. J. Smooth Muscle Res., 2008, 44(2), 83-93.
    • (2008) J. Smooth Muscle Res , vol.44 , Issue.2 , pp. 83-93
    • Ito, A.1    Hagiyama, M.2    Oonuma, J.3
  • 51
    • 77952868792 scopus 로고    scopus 로고
    • Mast cell-orchestrated immunity to pathogens
    • Abraham, S.N.; St John, AL. Mast cell-orchestrated immunity to pathogens. Nat. Rev. Immunol., 2010, 10(6), 440-452.
    • (2010) Nat Rev. Immunol , vol.10 , Issue.6 , pp. 440-452
    • Abraham, S.N.1    St John, A.L.2
  • 52
    • 36849072350 scopus 로고    scopus 로고
    • The mast cell and allergic diseases: Role in pathogenesis and implications for therapy
    • Brown, J.M.; Wilson, T.M.; Metcalfe, D.D. The mast cell and allergic diseases: role in pathogenesis and implications for therapy. Clin. Exp. Allergy, 2008, 38(1), 4-18.
    • (2008) Clin. Exp. Allergy , vol.38 , Issue.1 , pp. 4-18
    • Brown, J.M.1    Wilson, T.M.2    Metcalfe, D.D.3
  • 53
    • 78649518547 scopus 로고    scopus 로고
    • Mast cells: Emerging sentinel innate immune cells with diverse role in immunity
    • Kumar, V.; Sharma, A. Mast cells: Emerging sentinel innate immune cells with diverse role in immunity. Mol. Immunol., 2010, 48(1-3), 14-25.
    • (2010) Mol. Immunol , vol.48 , Issue.1-3 , pp. 14-25
    • Kumar, V.1    Sharma, A.2
  • 57
    • 24644462937 scopus 로고    scopus 로고
    • Mast cells and eosinophils: A novel link between inflammation and angiogenesis in allergic diseases
    • Puxeddu, I.; Ribatti, D.; Crivellato, E.; Levi-Schaffer, F. Mast cells and eosinophils: A novel link between inflammation and angiogenesis in allergic diseases. J. Allergy Clin. Immunol., 2005, 116(3), 531-536.
    • (2005) J. Allergy Clin. Immunol , vol.116 , Issue.3 , pp. 531-536
    • Puxeddu, I.1    Ribatti, D.2    Crivellato, E.3    Levi-Schaffer, F.4
  • 58
    • 77954115305 scopus 로고    scopus 로고
    • Mast cells in allergy and infection: Versatile effector and regulatory cells in innate and adaptive immunity
    • Galli, S.J.; Tsai, M. Mast cells in allergy and infection: Versatile effector and regulatory cells in innate and adaptive immunity. Eur. J. Immunol., 2010, 40, 1843-1851.
    • (2010) Eur. J. Immunol , vol.40 , pp. 1843-1851
    • Galli, S.J.1    Tsai, M.2
  • 59
    • 79953713651 scopus 로고    scopus 로고
    • Biological implications of preformed mast cell mediators
    • Lundequist, A.; Pejler, G. Biological implications of preformed mast cell mediators. Cell. Mol. Life Sci., 2011, 68(6), 965-975.
    • (2011) Cell. Mol. Life Sci , vol.68 , Issue.6 , pp. 965-975
    • Lundequist, A.1    Pejler, G.2
  • 60
    • 78149357276 scopus 로고    scopus 로고
    • Interactions between the immune and nervous systems in pain
    • Ren, K.; Dubner, R. Interactions between the immune and nervous systems in pain. Nat. Med., 2010, 16(11), 1267-1276.
    • (2010) Nat. Med , vol.16 , Issue.11 , pp. 1267-1276
    • Ren, K.1    Dubner, R.2
  • 61
    • 70349279924 scopus 로고    scopus 로고
    • Physiological and pathophysiological functions of intestinal mast cells
    • Bischoff, S.C. Physiological and pathophysiological functions of intestinal mast cells. Semin. Immunopathol., 2009, 31(2), 185-205.
    • (2009) Semin. Immunopathol , vol.31 , Issue.2 , pp. 185-205
    • Bischoff, S.C.1
  • 62
    • 34248186535 scopus 로고    scopus 로고
    • Mast cells in the pathogenesis of rheumatic diseases and as potential targets for anti-rheumatic therapy
    • Eklund, K.K. Mast cells in the pathogenesis of rheumatic diseases and as potential targets for anti-rheumatic therapy. Immunol. Rev., 2007, 217, 38-52.
    • (2007) Immunol. Rev , vol.217 , pp. 38-52
    • Eklund, K.K.1
  • 63
    • 34447271491 scopus 로고    scopus 로고
    • Mucosal mast cells are pivotal elements in inflammatory bowel disease that connect the dots: Stress, intestinal hyperpermeability and inflammation
    • Farhadi, A.; Fields, J.Z.; Keshavarzian, A. Mucosal mast cells are pivotal elements in inflammatory bowel disease that connect the dots: stress, intestinal hyperpermeability and inflammation. World J. Gastroenterol., 2007, 13(22), 3027-3030.
    • (2007) World J. Gastroenterol , vol.13 , Issue.22 , pp. 3027-3030
    • Farhadi, A.1    Fields, J.Z.2    Keshavarzian, A.3
  • 65
    • 57149091790 scopus 로고    scopus 로고
    • Role of Mast Cells in Progressive Renal Diseases
    • Holdsworth, S.R.; Summers, S.A. Role of Mast Cells in Progressive Renal Diseases. J. Am. Soc. Nephrol., 2008, 19(12), 2254-2261.
    • (2008) J. Am. Soc. Nephrol , vol.19 , Issue.12 , pp. 2254-2261
    • Holdsworth, S.R.1    Summers, S.A.2
  • 66
    • 65249129057 scopus 로고    scopus 로고
    • Mast cells: Novel clinical perspectives from recent insights
    • Kneilling, M.; Rocken, M. Mast cells: novel clinical perspectives from recent insights. Exp. Dermatol., 2009, 18, 488-496.
    • (2009) Exp. Dermatol , vol.18 , pp. 488-496
    • Kneilling, M.1    Rocken, M.2
  • 67
    • 56649085176 scopus 로고    scopus 로고
    • Brain mast cells link the immune system to anxiety-like behavior
    • Nautiyal, K.M.; Ribeiro, A.C.; Pfaff, D.W.; Silver, R. Brain mast cells link the immune system to anxiety-like behavior. Proc. Natl. Acad. Sci. U.S.A., 2008, 105(46), 18053-18057.
    • (2008) Proc. Natl. Acad. Sci. U.S.A , vol.105 , Issue.46 , pp. 18053-18057
    • Nautiyal, K.M.1    Ribeiro, A.C.2    Pfaff, D.W.3    Silver, R.4
  • 68
    • 39649099817 scopus 로고    scopus 로고
    • Mast cells and immunological skin diseases
    • Navi, D.; Saegusa, J.; Liu, F.T. Mast cells and immunological skin diseases. Clin. Rev. Allergy Immunol., 2007, 33(1-2), 144-155.
    • (2007) Clin. Rev. Allergy Immunol , vol.33 , Issue.1-2 , pp. 144-155
    • Navi, D.1    Saegusa, J.2    Liu, F.T.3
  • 70
    • 0347993174 scopus 로고    scopus 로고
    • Critical role of mast cells in inflammatory diseases and the effect of acute stress
    • Theoharides, T.C.; Cochrane, D.E. Critical role of mast cells in inflammatory diseases and the effect of acute stress. J. Neuroimmunol., 2004, 146(1-2), 1-12.
    • (2004) J. Neuroimmunol , vol.146 , Issue.1-2 , pp. 1-12
    • Theoharides, T.C.1    Cochrane, D.E.2
  • 71
    • 34247512849 scopus 로고    scopus 로고
    • The critical role of mast cells in allergy and inflammation
    • Theoharides, T.C; Kalogeromitros, D. The critical role of mast cells in allergy and inflammation. Ann, N Y Acad. Sci., 2006, 1088, 78-99.
    • (2006) Ann, N Y Acad. Sci , vol.1088 , pp. 78-99
    • Theoharides, T.C.1    Kalogeromitros, D.2
  • 72
    • 70449389370 scopus 로고    scopus 로고
    • Mast cells: Target and source of neuropeptides
    • Tore, F.; Tuncel, N. Mast cells: target and source of neuropeptides. Curr. Pharm. Des., 2009, 15(29), 3433-3445.
    • (2009) Curr. Pharm. Des , vol.15 , Issue.29 , pp. 3433-3445
    • Tore, F.1    Tuncel, N.2
  • 73
    • 0033661848 scopus 로고    scopus 로고
    • N-Acylethanolamines and precursor phospholipids - relation to cell injury
    • Hansen, H.S.; Moesgaard, B.; Hansen, H.H.; Petersen, G. N-Acylethanolamines and precursor phospholipids - relation to cell injury. Chem. Phys. Lipids, 2000, 108(1-2), 135-150.
    • (2000) Chem. Phys. Lipids , vol.108 , Issue.1-2 , pp. 135-150
    • Hansen, H.S.1    Moesgaard, B.2    Hansen, H.H.3    Petersen, G.4
  • 74
    • 0014579111 scopus 로고
    • N-acylphosphatidylethanolamine, a phospholipid that is rapidly metabolized during the early germination of
    • Dawson, R.M.; Clarke, N.; Quarles, R.H. N-acylphosphatidylethanolamine, a phospholipid that is rapidly metabolized during the early germination of Pea seeds. Biochem. J., 1969, 114(2), 265-7.
    • (1969) Pea Seeds. Biochem. J , vol.114 , Issue.2 , pp. 265-267
    • Dawson, R.M.1    Clarke, N.2    Quarles, R.H.3
  • 75
    • 0014667231 scopus 로고
    • N-Acylphosphatidylethanolamines: Occurrence in nature, structure and stereochemistry
    • Aneja, R.; Chadha, J.S.; Knaggs, J.A. N-Acylphosphatidylethanolamines: occurrence in nature, structure and stereochemistry. Biochem. Biophys. Res. Commun., 1969, 36(3), 401-6.
    • (1969) Biochem. Biophys. Res. Commun , vol.36 , Issue.3 , pp. 401-406
    • Aneja, R.1    Chadha, J.S.2    Knaggs, J.A.3
  • 76
    • 0017313261 scopus 로고
    • Phosphatidyl-(N-acyl)-ethanolamine. A lipid component of mammalian epidermis
    • Gray, G.M. Phosphatidyl-(N-acyl)-ethanolamine. A lipid component of mammalian epidermis. Biochim. Biophys. Acta, 1976, 431(1), 1-8.
    • (1976) Biochim. Biophys. Acta , vol.431 , Issue.1 , pp. 1-8
    • Gray, G.M.1
  • 78
    • 0019331582 scopus 로고
    • Identification of N-acylethanolamine phosphoglycerides and acylphosphatidylglycerol as the phospholipids which disappear as Dictyostelium discoideum cells aggregate
    • Ellingson, J.S. Identification of N-acylethanolamine phosphoglycerides and acylphosphatidylglycerol as the phospholipids which disappear as Dictyostelium discoideum cells aggregate. Biochemistry, 1980, 19(26), 6176-6182.
    • (1980) Biochemistry , vol.19 , Issue.26 , pp. 6176-6182
    • Ellingson, J.S.1
  • 80
    • 0019308380 scopus 로고
    • Accumulation of N-acylethanolamine glycerophospholipids in infarcted myocardium
    • Epps, D.E.; Natarajan, V.; Schmid, P.C.; Schmid, H.O. Accumulation of N-acylethanolamine glycerophospholipids in infarcted myocardium. Biochim. Biophys. Acta, 1980, 618(3), 420-430.
    • (1980) Biochim. Biophys. Acta , vol.618 , Issue.3 , pp. 420-430
    • Epps, D.E.1    Natarajan, V.2    Schmid, P.C.3    Schmid, H.O.4
  • 83
    • 0033919878 scopus 로고    scopus 로고
    • Age dependent accumulation of N-acyl-ethanolamine phospholipids in ischemic rat brain. A (31)P NMR and enzyme activity study
    • Moesgaard, B.; Petersen, G.; Jaroszewski, J.W.; Hansen, H.S. Age dependent accumulation of N-acyl-ethanolamine phospholipids in ischemic rat brain. A (31)P NMR and enzyme activity study. J. Lipid. Res., 2000, 41(6), 985-990.
    • (2000) J. Lipid. Res , vol.41 , Issue.6 , pp. 985-990
    • Moesgaard, B.1    Petersen, G.2    Jaroszewski, J.W.3    Hansen, H.S.4
  • 84
    • 0024392351 scopus 로고
    • Changes in lipid composition of neuroblastoma C1300 N18 cell during differentiation
    • Gulaya, N.M.; Volkov, G.L.; Klimashevsky, V.M.; Govseeva, N.N.; Melnik, A.A. Changes in lipid composition of neuroblastoma C1300 N18 cell during differentiation. Neuroscience, 1989, 30(1), 153-164.
    • (1989) Neuroscience , vol.30 , Issue.1 , pp. 153-164
    • Gulaya, N.M.1    Volkov, G.L.2    Klimashevsky, V.M.3    Govseeva, N.N.4    Melnik, A.A.5
  • 85
    • 0029756752 scopus 로고    scopus 로고
    • Biosynthesis of anandamide and related acylethanolamides in mouse J774 macrophages and N18 neuroblastoma cells
    • Di Marzo, V.; De Petrocellis, L.; Sepe, N.; Buono, A. Biosynthesis of anandamide and related acylethanolamides in mouse J774 macrophages and N18 neuroblastoma cells. Biochem. J., 1996, 316 (Pt 3), 977-984.
    • (1996) Biochem. J , vol.316 , Issue.Pt 3 , pp. 977-984
    • Di Marzo, V.1    de Petrocellis, L.2    Sepe, N.3    Buono, A.4
  • 86
    • 0025676296 scopus 로고
    • N-acylated glycerophospholipids and their derivatives
    • Schmid, H.H.; Schmid, P.C.; Natarajan, V. N-acylated glycerophospholipids and their derivatives. Prog. Lipid Res., 1990, 29(1), 1-43.
    • (1990) Prog. Lipid Res , vol.29 , Issue.1 , pp. 1-43
    • Schmid, H.H.1    Schmid, P.C.2    Natarajan, V.3
  • 87
    • 0032526815 scopus 로고    scopus 로고
    • Accumulation of various N-acylethanolamines including N-arachidonoylethanolamine (anandamide) in cadmium chloride-administered rat testis
    • Kondo, S.; Sugiura, T.; Kodaka, T.; Kudo N, Waku, K.; Tokumura, A. Accumulation of various N-acylethanolamines including N-arachidonoylethanolamine (anandamide) in cadmium chloride-administered rat testis. Arch. Biochem. Biophys., 1998, 354(2), 303-310.
    • (1998) Arch. Biochem. Biophys , vol.354 , Issue.2 , pp. 303-310
    • Kondo, S.1    Sugiura, T.2    Kodaka, T.3    Kudo, N.4    Waku, K.5    Tokumura, A.6
  • 88
    • 0030791958 scopus 로고    scopus 로고
    • Anandamide and other N-acylethanolamines in mouse peritoneal macrophages
    • Schmid, P.C.; Kuwae, T.; Krebsbach, R.J.; Schmid, H.H. Anandamide and other N-acylethanolamines in mouse peritoneal macrophages. Chem. Phys. Lipids, 1997, 87(2), 103-110.
    • (1997) Chem. Phys. Lipids , vol.87 , Issue.2 , pp. 103-110
    • Schmid, P.C.1    Kuwae, T.2    Krebsbach, R.J.3    Schmid, H.H.4
  • 89
    • 0000821035 scopus 로고    scopus 로고
    • N-Acylethanolamines: Formation and molecular composition of a new class of plant lipids
    • Chapman, K.D.; Tripathy, S.; Venables, B.; Desouza, A.D. N-Acylethanolamines: formation and molecular composition of a new class of plant lipids. Plant Physiol., 1998, 116(3), 1163-1168.
    • (1998) Plant Physiol , vol.116 , Issue.3 , pp. 1163-1168
    • Chapman, K.D.1    Tripathy, S.2    Venables, B.3    Desouza, A.D.4
  • 90
    • 0013785299 scopus 로고
    • Precursors of N-acylethanolamines in hen's egg-yolk lipid
    • Wren, J.J.; Merryfield, D.S. Precursors of N-acylethanolamines in hen's egg-yolk lipid. Biochim. Biophys. Acta, 1965, 98(3), 589-597.
    • (1965) Biochim. Biophys. Acta , vol.98 , Issue.3 , pp. 589-597
    • Wren, J.J.1    Merryfield, D.S.2
  • 91
    • 67650172193 scopus 로고    scopus 로고
    • Genetic manipulation of palmitoylethanolamide production and inactivation in Saccharomyces cerevisiae
    • Muccioli, G.G.; Sia, A.; Muchowski, P.J.; Stella, N. Genetic manipulation of palmitoylethanolamide production and inactivation in Saccharomyces cerevisiae. PLoS One, 2009, 4(6), e5942.
    • (2009) PLoS One , vol.4 , Issue.6
    • Muccioli, G.G.1    Sia, A.2    Muchowski, P.J.3    Stella, N.4
  • 92
    • 78651171367 scopus 로고
    • Fatty acid amides of ethanolamine in mammalian tissues
    • Bachur, N.R.; Masek, K.; Melmon, K.L.; Udenfriend, S. Fatty acid amides of ethanolamine in mammalian tissues. J. Biol. Chem., 1965, 240, 1019-1024.
    • (1965) J. Biol. Chem , vol.240 , pp. 1019-1024
    • Bachur, N.R.1    Masek, K.2    Melmon, K.L.3    Udenfriend, S.4
  • 93
    • 77957575142 scopus 로고    scopus 로고
    • Lipid profiling reveals tissue-specific differences for ethanolamide lip ids in mice lacking Fatty Acid amide hydrolase
    • Kilaru, A.; Isaac, G.; Tamura, P.; Baxter, D.; Duncan, S.R.; Venables, B.J.; Welti, R.; Koulen, P.; Chapman, K.D. Lipid profiling reveals tissue-specific differences for ethanolamide lip ids in mice lacking Fatty Acid amide hydrolase. Lipids, 2010, 45(9), 863-875.
    • (2010) Lipids , vol.45 , Issue.9 , pp. 863-875
    • Kilaru, A.1    Isaac, G.2    Tamura, P.3    Baxter, D.4    Duncan, S.R.5    Venables, B.J.6    Welti, R.7    Koulen, P.8    Chapman, K.D.9
  • 94
    • 61649124735 scopus 로고    scopus 로고
    • Role of acylethanolamides in the gastrointestinal tract with special reference to food intake and energy balance
    • Borrelli, F.; Izzo, A.A. Role of acylethanolamides in the gastrointestinal tract with special reference to food intake and energy balance. Best Pract. Res. Clin. Endocrinol. Metab., 2009, 23(1), 33-49.
    • (2009) Best Pract. Res. Clin. Endocrinol. Metab , vol.23 , Issue.1 , pp. 33-49
    • Borrelli, F.1    Izzo, A.A.2
  • 95
    • 78049321186 scopus 로고    scopus 로고
    • Simultaneous measurement of three N-acylethanolamides in human bio-matrices using ultra performance liquid chromatography-tandem mass spectrometry
    • Lam, P.M.; Marczylo, T.H.; Konje, J.C. Simultaneous measurement of three N-acylethanolamides in human bio-matrices using ultra performance liquid chromatography-tandem mass spectrometry. Anal. Bioanal. Chem., 2010, 398(5), 2089-2097.
    • (2010) Anal. Bioanal. Chem , vol.398 , Issue.5 , pp. 2089-2097
    • Lam, P.M.1    Marczylo, T.H.2    Konje, J.C.3
  • 101
    • 33646521012 scopus 로고    scopus 로고
    • Diurnal variation of arachidonoylethanolamine, palmitoylethanolamide and oleoylethanolamide in the brain of the rat
    • Murillo-Rodriguez, E.; Désarnaud, F.; Prospéro-García, O. Diurnal variation of arachidonoylethanolamine, palmitoylethanolamide and oleoylethanolamide in the brain of the rat. Life Sci., 2006, 79(1), 30-37.
    • (2006) Life Sci , vol.79 , Issue.1 , pp. 30-37
    • Murillo-Rodriguez, E.1    Désarnaud, F.2    Prospéro-García, O.3
  • 102
    • 33750452664 scopus 로고    scopus 로고
    • Changes in endocannabinoid and palmitoylethanolamide levels in eye tissues of patients with diabetic retinopathy and age-related macular degeneration
    • Matias, I.; Wang, J.W.; Moriello, A.S.; Nieves, A.; Woodward, D.F.; Di Marzo, V. Changes in endocannabinoid and palmitoylethanolamide levels in eye tissues of patients with diabetic retinopathy and age-related macular degeneration. Prostaglandins Leukot. Essent. Fatty Acids, 2006, 75(6), 413-8.
    • (2006) Prostaglandins Leukot Essent. Fatty Acids , vol.75 , Issue.6 , pp. 413-418
    • Matias, I.1    Wang, J.W.2    Moriello, A.S.3    Nieves, A.4    Woodward, D.F.5    Di Marzo, V.6
  • 105
    • 0037036436 scopus 로고    scopus 로고
    • Astrocytes in culture produce anandamide and other acylethanolamides
    • Walter, L.; Franklin, A.; Witting, A.; Moller, T.; Stella, N. Astrocytes in culture produce anandamide and other acylethanolamides. J. Biol. Chem., 2002, 277(23), 20869-20876.
    • (2002) J. Biol. Chem , vol.277 , Issue.23 , pp. 20869-20876
    • Walter, L.1    Franklin, A.2    Witting, A.3    Moller, T.4    Stella, N.5
  • 106
    • 37349006157 scopus 로고    scopus 로고
    • Microglia produce and hydrolyze palmitoylethanolamide
    • Muccioli, G.G.; Stella, N. Microglia produce and hydrolyze palmitoylethanolamide. Neuropharmacology, 2008, 54(1), 16-22.
    • (2008) Neuropharmacology , vol.54 , Issue.1 , pp. 16-22
    • Muccioli, G.G.1    Stella, N.2
  • 107
    • 0028589390 scopus 로고
    • Formation and inactivation of endogenous cannabinoid anandamide in central neurons
    • Di Marzo, V.; Fontana, A., Cadas, H.; Schinelli, S.; Cimino, G.; Schwartz, J.C.; Piomelli, D. Formation and inactivation of endogenous cannabinoid anandamide in central neurons. Nature, 1994, 372(6507), 686-691.
    • (1994) Nature , vol.372 , Issue.6507 , pp. 686-691
    • Di Marzo, V.1    Fontana, A.2    Cadas, H.3    Schinelli, S.4    Cimino, G.5    Schwartz, J.C.6    Piomelli, D.7
  • 108
    • 0035902918 scopus 로고    scopus 로고
    • Receptor-dependent formation of endogenous cannabinoids in cortical neurons
    • Stella, N.; Piomelli, D. Receptor-dependent formation of endogenous cannabinoids in cortical neurons. Eur J Pharmacol. 2001;425(3):189-196.
    • (2001) Eur J Pharmacol , vol.425 , Issue.3 , pp. 189-196
    • Stella, N.1    Piomelli, D.2
  • 109
    • 19444386886 scopus 로고    scopus 로고
    • Involvement of the cannabimimetic compound, N-palmitoylethanolamine, in inflammatory and neuropathic conditions. A review of the available pre-clinical data and first human studies
    • Darmani, N.A.; Izzo, A.A.; Degenhardt, B.; Valenti, M.; Scaglione, G.; Capasso, F.; Sorrentini, I.; Di Marzo, V. Involvement of the cannabimimetic compound, N-palmitoylethanolamine, in inflammatory and neuropathic conditions. A review of the available pre-clinical data and first human studies. Neuropharmacology, 2005, 48(8), 1154-1163.
    • (2005) Neuropharmacology , vol.48 , Issue.8 , pp. 1154-1163
    • Darmani, N.A.1    Izzo, A.A.2    Degenhardt, B.3    Valenti, M.4    Scaglione, G.5    Capasso, F.6    Sorrentini, I.7    Di Marzo, V.8
  • 112
    • 0036330324 scopus 로고    scopus 로고
    • Release of fatty acid amides in a patient with hemispheric stroke: A microdialysis study
    • Schäbitz, W.R.; Giuffrida, A.; Berger, C.; Aschoff, A.; Schwaninger, M.; Schwab, S.; Piomelli, D. Release of fatty acid amides in a patient with hemispheric stroke: a microdialysis study. Stroke, 2002, 33(8), 2112-2114.
    • (2002) Stroke , vol.33 , Issue.8 , pp. 2112-2114
    • Schäbitz, W.R.1    Giuffrida, A.2    Berger, C.3    Aschoff, A.4    Schwaninger, M.5    Schwab, S.6    Piomelli, D.7
  • 114
    • 0042320663 scopus 로고    scopus 로고
    • Palmitoylethanolamide increases after focal cerebral ischemia and potentiates microglial cell motility
    • Franklin, A.; Parmentier-Batteur, S.; Walter, L.; Greenberg, D.A.; Stella, N. Palmitoylethanolamide increases after focal cerebral ischemia and potentiates microglial cell motility. J. Neurosci., 2003, 23(21), 7767-7775.
    • (2003) J. Neurosci , vol.23 , Issue.21 , pp. 7767-7775
    • Franklin, A.1    Parmentier-Batteur, S.2    Walter, L.3    Greenberg, D.A.4    Stella, N.5
  • 116
    • 77649342807 scopus 로고    scopus 로고
    • Endocannabinoid Research Group. Levels of endocannabinoids and palmitoylethanolamide and their pharmacological manipulation in chronic granulomatous inflammation in rats
    • De Filippis, D.; D'Amico, A.; Cipriano, M.; Petrosino, S.; Orlando, P.; Di Marzo, V.; Iuvone, T., Endocannabinoid Research Group. Levels of endocannabinoids and palmitoylethanolamide and their pharmacological manipulation in chronic granulomatous inflammation in rats. Pharmacol. Res. 2010, 61(4), 321-328.
    • (2010) Pharmacol. Res , vol.61 , Issue.4 , pp. 321-328
    • de Filippis, D.1    D'amico, A.2    Cipriano, M.3    Petrosino, S.4    Orlando, P.5    Di Marzo, V.6    Iuvone, T.7
  • 121
    • 0034161858 scopus 로고    scopus 로고
    • Stressinduced generation of N-acylethanolamines in mouse epidermal JB6 P+ cells
    • Berdyshev, E.V.; Schmid, P.C.; Dong, Z.; Schmid, H.H. Stressinduced generation of N-acylethanolamines in mouse epidermal JB6 P+ cells. Biochem. J., 2000, 2, 369-374.
    • (2000) Biochem. J , vol.2 , pp. 369-374
    • Berdyshev, E.V.1    Schmid, P.C.2    Dong, Z.3    Schmid, H.H.4
  • 122
    • 77957787918 scopus 로고    scopus 로고
    • IL-33 is produced by mast cells and regulates IgE-dependent inflammation
    • Hsu, C.L.; Neilsen, C.V.; Bryce, P.J. IL-33 is produced by mast cells and regulates IgE-dependent inflammation. PLoS One, 2010, 5(8), e11944.
    • (2010) PLoS One , vol.5 , Issue.8
    • Hsu, C.L.1    Neilsen, C.V.2    Bryce, P.J.3
  • 123
    • 34248141140 scopus 로고    scopus 로고
    • The essential role of mast cells in orchestrating inflammation
    • Kinet, J.P. The essential role of mast cells in orchestrating inflammation. Immunol. Rev., 2007, 217, 5-7.
    • (2007) Immunol. Rev , vol.217 , pp. 5-7
    • Kinet, J.P.1
  • 124
    • 34248137929 scopus 로고    scopus 로고
    • Differential release of mast cell mediators and the pathogenesis of inflammation
    • Theoharides, T.C.; Kempuraj, D.; Tagen, M.; Conti, P.; Kalogeromitros, D. Differential release of mast cell mediators and the pathogenesis of inflammation. Immunol. Rev., 2007, 217, 65-78
    • (2007) Immunol. Rev , vol.217 , pp. 65-78
    • Theoharides, T.C.1    Kempuraj, D.2    Tagen, M.3    Conti, P.4    Kalogeromitros, D.5
  • 125
    • 77950517721 scopus 로고    scopus 로고
    • Mast cells as early responders in the regulation of acute blood-brain barrier changes after cerebral ischemia and hemorrhage
    • Lindsberg, P.J.; Strbian, D.; Karjalainen-Lindsberg, M.L. Mast cells as early responders in the regulation of acute blood-brain barrier changes after cerebral ischemia and hemorrhage. J. Cereb. Blood Flow Metab., 2010, 30(4), 689-702.
    • (2010) J. Cereb. Blood Flow Metab , vol.30 , Issue.4 , pp. 689-702
    • Lindsberg, P.J.1    Strbian, D.2    Karjalainen-Lindsberg, M.L.3
  • 126
    • 77951591750 scopus 로고    scopus 로고
    • Role of mast cell activation in inducing microglial cells to release neurotrophin
    • Yuan, H.; Zhu, X.; Zhou, S.; Chen, Q.; Zhu, X.; Ma, X.; He, X.; Tian, M.; Shi, X. Role of mast cell activation in inducing microglial cells to release neurotrophin. J. Neurosci. Res., 2010, 88(6), 1348-1354.
    • (2010) J. Neurosci. Res , vol.88 , Issue.6 , pp. 1348-1354
    • Yuan, H.1    Zhu, X.2    Zhou, S.3    Chen, Q.4    Zhu, X.5    Ma, X.6    He, X.7    Tian, M.8    Shi, X.9
  • 127
    • 34248545448 scopus 로고    scopus 로고
    • Psychoneuroimmunology cross-talk between the immune and nervous systems
    • Ziemssen, T.; Kern, S. Psychoneuroimmunology cross-talk between the immune and nervous systems. J. Neurol., 2007, 254(2), II8-11.
    • (2007) J. Neurol , vol.254 , Issue.2 , pp. 8-11
    • Ziemssen, T.1    Kern, S.2
  • 128
    • 0030751182 scopus 로고    scopus 로고
    • Influence of fatty acid ethanolamides and delta9-tetrahydrocannabinol on cytokine and arachidonate release by mononuclear cells
    • Berdyshev, E.V.; Boichot, E.; Germain, N.; Allain, N.; Anger, J.P.; Lagente, V. Influence of fatty acid ethanolamides and delta9-tetrahydrocannabinol on cytokine and arachidonate release by mononuclear cells. Eur. J. Pharmacol., 1997, 330(2-3), 231-240.
    • (1997) Eur. J. Pharmacol , vol.330 , Issue.2-3 , pp. 231-240
    • Berdyshev, E.V.1    Boichot, E.2    Germain, N.3    Allain, N.4    Anger, J.P.5    Lagente, V.6
  • 129
    • 0034604755 scopus 로고    scopus 로고
    • Inhibition of nitric oxide production in RAW264.7 macrophages by cannabinoids and palmitoylethanolamide
    • Ross, R.A.; Brockie, H.C.; Pertwee, R.G. Inhibition of nitric oxide production in RAW264.7 macrophages by cannabinoids and palmitoylethanolamide. Eur. J. Pharmacol., 2000, 401(2), 121-130.
    • (2000) Eur. J. Pharmacol , vol.401 , Issue.2 , pp. 121-130
    • Ross, R.A.1    Brockie, H.C.2    Pertwee, R.G.3
  • 130
    • 0032540995 scopus 로고    scopus 로고
    • Effects of cannabinoid receptor ligands on LPS-induced pulmonary inflammation in mice
    • Berdyshev, E.V.; Boichot, E.; Corbel, M.; Germain, N.; Lagente, V. Effects of cannabinoid receptor ligands on LPS-induced pulmonary inflammation in mice. Life Sci., 1998, 63(8), PL125-129.
    • (1998) Life Sci , vol.63 , Issue.8 , pp. 125-129
    • Berdyshev, E.V.1    Boichot, E.2    Corbel, M.3    Germain, N.4    Lagente, V.5
  • 131
    • 24744448386 scopus 로고    scopus 로고
    • Endogenous cannabinoid receptor agonists inhibit neurogenic inflammations in guinea pig airways
    • Yoshihara, S.; Morimoto, H.; Ohori, M.; Yamada, Y.; Abe, T.; Arisaka, O. Endogenous cannabinoid receptor agonists inhibit neurogenic inflammations in guinea pig airways. Int. Arch. Allergy Immunol., 2005, 138(1), 80-7.
    • (2005) Int. Arch. Allergy Immunol , vol.138 , Issue.1 , pp. 80-87
    • Yoshihara, S.1    Morimoto, H.2    Ohori, M.3    Yamada, Y.4    Abe, T.5    Arisaka, O.6
  • 132
    • 0029865544 scopus 로고    scopus 로고
    • N-(2-hydroxyethyl)hexadecanamide is orally active in reducing edema formation and inflammatory hyperalgesia by down-modulating mast cell activation
    • Mazzari, S.; Canella, R.; Petrelli, L.; Marcolongo, G.; Leon, A. N-(2-hydroxyethyl)hexadecanamide is orally active in reducing edema formation and inflammatory hyperalgesia by down-modulating mast cell activation. Eur. J. Pharmacol., 1996, 300(3), 227-236.
    • (1996) Eur. J. Pharmacol , vol.300 , Issue.3 , pp. 227-236
    • Mazzari, S.1    Canella, R.2    Petrelli, L.3    Marcolongo, G.4    Leon, A.5
  • 135
    • 49249094482 scopus 로고    scopus 로고
    • Study of the regulation of the endocannabinoid system in a virus model of multiple sclerosis reveals a therapeutic effect of palmitoylethanolamide
    • Loría, F.; Petrosino, S.; Mestre, L.; Spagnolo, A.; Correa, F.; Hernangómez, M.; Guaza, C.; Di Marzo, V.; Docagne, F. Study of the regulation of the endocannabinoid system in a virus model of multiple sclerosis reveals a therapeutic effect of palmitoylethanolamide. Eur. J. Neurosci., 2008, 28(4), 633-641.
    • (2008) Eur. J. Neurosci , vol.28 , Issue.4 , pp. 633-641
    • Loría, F.1    Petrosino, S.2    Mestre, L.3    Spagnolo, A.4    Correa, F.5    Hernangómez, M.6    Guaza, C.7    Di Marzo, V.8    Docagne, F.9
  • 137
    • 0035843772 scopus 로고    scopus 로고
    • Antinociceptive activity of the endogenous fatty acid amide, palmitoylethanolamide
    • Calignano, A.; La Rana, G.; Piomelli, D. Antinociceptive activity of the endogenous fatty acid amide, palmitoylethanolamide. Eur. J. Pharmacol, 2001, 419(2-3), 191-198.
    • (2001) Eur. J. Pharmacol , vol.419 , Issue.2-3 , pp. 191-198
    • Calignano, A.1    la Rana, G.2    Piomelli, D.3
  • 139
    • 5344277612 scopus 로고    scopus 로고
    • Selective antiepileptic effects of N-palmitoylethanolamide, a putative endocannabinoid
    • Sheerin, A.H.; Zhang, X.; Saucier, D.M.; Corcoran, M.E. Selective antiepileptic effects of N-palmitoylethanolamide, a putative endocannabinoid. Epilepsia, 2004, 45(10), 1184-1188.
    • (2004) Epilepsia , vol.45 , Issue.10 , pp. 1184-1188
    • Sheerin, A.H.1    Zhang, X.2    Saucier, D.M.3    Corcoran, M.E.4
  • 140
    • 0022498237 scopus 로고
    • N-acylethanolamine phospholipid metabolism in normal and ischemic rat brain
    • Natarajan, V.; Schmid, P.C.; Schmid, H.H. N-acylethanolamine phospholipid metabolism in normal and ischemic rat brain. Biochim. Biophys. Acta, 1986, 878(1), 32-41.
    • (1986) Biochim. Biophys. Acta , vol.878 , Issue.1 , pp. 32-41
    • Natarajan, V.1    Schmid, P.C.2    Schmid, H.H.3
  • 142
    • 53349089891 scopus 로고    scopus 로고
    • The endogenous fatty acid amide, palmitoylethanolamide, has anti-allodynic and antihyperalgesic effects in a murine model of neuropathic pain: Involvement of CB1, TRPV1 and PPARgamma receptors and neurotrophic factors
    • Costa, B.; Comelli, F.; Bettoni, I.; Colleoni, M.; Giagnoni, G. The endogenous fatty acid amide, palmitoylethanolamide, has anti-allodynic and antihyperalgesic effects in a murine model of neuropathic pain: involvement of CB1, TRPV1 and PPARgamma receptors and neurotrophic factors. Pain, 2008, 139(3), 541-550.
    • (2008) Pain , vol.139 , Issue.3 , pp. 541-550
    • Costa, B.1    Comelli, F.2    Bettoni, I.3    Colleoni, M.4    Giagnoni, G.5
  • 145
    • 79960209448 scopus 로고    scopus 로고
    • Effects of palmitoylethanolamide on release of mast cell peptidases and neurotrophic factors after spinal cord injury
    • Esposito, E.; Paterniti, I.; Mazzon, E.; Genovese, T.; Di Paola, R.; Galuppo, M.; Cuzzocrea, S. Effects of palmitoylethanolamide on release of mast cell peptidases and neurotrophic factors after spinal cord injury. Brain Behav. Immun., 2011, 25(6), 1099-1112.
    • (2011) Brain Behav. Immun , vol.25 , Issue.6 , pp. 1099-1112
    • Esposito, E.1    Paterniti, I.2    Mazzon, E.3    Genovese, T.4    Di Paola, R.5    Galuppo, M.6    Cuzzocrea, S.7
  • 147
    • 79959254383 scopus 로고    scopus 로고
    • Palmitoylethanolamide stimulation induces allopregnanolone synthesis in C6 cells and primary astrocytes: Involvement of peroxisome-proliferator activated receptor-a
    • Mattace Raso, G.; Esposito, E.; Vitiello, S.; Iacono, A.; Santoro, A.; D'Agostino, G.; Sasso, O.; Russo, R.; Piazza, P.V.; Calignano, A.; Meli, R. Palmitoylethanolamide stimulation induces allopregnanolone synthesis in C6 cells and primary astrocytes: involvement of peroxisome-proliferator activated receptor-a. J. Neuroendocrinol, 2011, 23(7), 591-600.
    • (2011) J. Neuroendocrinol , vol.23 , Issue.7 , pp. 591-600
    • Mattace Raso, G.1    Esposito, E.2    Vitiello, S.3    Iacono, A.4    Santoro, A.5    D'agostino, G.6    Sasso, O.7    Russo, R.8    Piazza, P.V.9    Calignano, A.10    Meli, R.11
  • 149
    • 0001674924 scopus 로고    scopus 로고
    • Bioactive long chain N-acylethanolamines in five species of edible bivalve molluscs. Possible implications for mollusc physiology and sea food industry
    • Sepe, N; De Petrocellis, L.; Montanaro, F.; Cimino, G.; Di Marzo, V. Bioactive long chain N-acylethanolamines in five species of edible bivalve molluscs. Possible implications for mollusc physiology and sea food industry. Biochim. Biophys. Acta, 1998, 1389(2), 101-111.
    • (1998) Biochim. Biophys. Acta , vol.1389 , Issue.2 , pp. 101-111
    • Sepe, N.1    de Petrocellis, L.2    Montanaro, F.3    Cimino, G.4    Di Marzo, V.5
  • 150
    • 0028837562 scopus 로고
    • Occurrence and postmortem generation of anandamide and other long-chain N-acylethanolamines in mammalian brain
    • Schmid, P.C.; Krebsbach, R.J.; Perry, S.R.; Dettmer, T.M.; Maasson, J.L.; Schmid, H.H. Occurrence and postmortem generation of anandamide and other long-chain N-acylethanolamines in mammalian brain. FEBS Lett., 1995, 375(1-2), 117-120.
    • (1995) FEBS Lett , vol.375 , Issue.1-2 , pp. 117-120
    • Schmid, P.C.1    Krebsbach, R.J.2    Perry, S.R.3    Dettmer, T.M.4    Maasson, J.L.5    Schmid, H.H.6
  • 153
    • 33845656509 scopus 로고    scopus 로고
    • Quantitative profiling of endocannabinoids and related compounds in rat brain using liquid chromatography-tandem electrospray ionization mass spectrometry
    • Richardson, D.; Ortori, C.A.; Chapman, V.; Kendall, DA.; Barrett, DA. Quantitative profiling of endocannabinoids and related compounds in rat brain using liquid chromatography-tandem electrospray ionization mass spectrometry. Anal Biochem., 2007, 360(2), 216-226.
    • (2007) Anal Biochem , vol.360 , Issue.2 , pp. 216-226
    • Richardson, D.1    Ortori, C.A.2    Chapman, V.3    Kendall, D.A.4    Barrett, D.A.5
  • 154
    • 34250658035 scopus 로고    scopus 로고
    • Short-term exposure to alcohol in rats affects brain levels of anandamide, other N-acylethanolamines and 2-arachidonoylglycerol
    • Rubio, M.; McHugh, D.; Fernández-Ruiz, J.; Bradshaw, H.; Walker, J.M. Short-term exposure to alcohol in rats affects brain levels of anandamide, other N-acylethanolamines and 2-arachidonoylglycerol. Neurosci. Lett., 2007, 421(3), 270-4.
    • (2007) Neurosci. Lett , vol.421 , Issue.3 , pp. 270-274
    • Rubio, M.1    McHugh, D.2    Fernández-Ruiz, J.3    Bradshaw, H.4    Walker, J.M.5
  • 159
    • 33749996485 scopus 로고    scopus 로고
    • Synergistic antinociceptive effects of anandamide, an endocannabinoid, and nonsteroidal anti-inflammatory drugs in peripheral tissue: A role for endogenous fatty-acid ethanolamides?
    • Guindon, J.; Loverme, J.; De Lean, A.; Piomelli, D.; Beaulieu, P. Synergistic antinociceptive effects of anandamide, an endocannabinoid, and nonsteroidal anti-inflammatory drugs in peripheral tissue: A role for endogenous fatty-acid ethanolamides? Eur. J. Pharmacol., 2006, 550(1-3), 68-77.
    • (2006) Eur. J. Pharmacol , vol.550 , Issue.1-3 , pp. 68-77
    • Guindon, J.1    Loverme, J.2    de Lean, A.3    Piomelli, D.4    Beaulieu, P.5
  • 160
    • 23944488765 scopus 로고    scopus 로고
    • Increased plasma concentrations of palmitoylethanolamide, an endogenous fatty acid amide, affect oxidative damage of human low-density lipoproteins: An in vitro study
    • Zolese, G.; Bacchetti, T.; Ambrosini, A.; Wozniak, M.; Bertoli, E.; Ferretti, G. Increased plasma concentrations of palmitoylethanolamide, an endogenous fatty acid amide, affect oxidative damage of human low-density lipoproteins: an in vitro study. Atherosclerosis, 2005, 182(1), 47-55.
    • (2005) Atherosclerosis , vol.182 , Issue.1 , pp. 47-55
    • Zolese, G.1    Bacchetti, T.2    Ambrosini, A.3    Wozniak, M.4    Bertoli, E.5    Ferretti, G.6
  • 162
    • 67650617724 scopus 로고    scopus 로고
    • Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress
    • Hill, M.N.; Miller, G.E.; Carrier, E.J.; Gorzalka, B.B.; Hillard, C.J. Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress. Psychoneuroendocrinology, 2009, 34(8), 1257-1262.
    • (2009) Psychoneuroendocrinology , vol.34 , Issue.8 , pp. 1257-1262
    • Hill, M.N.1    Miller, G.E.2    Carrier, E.J.3    Gorzalka, B.B.4    Hillard, C.J.5
  • 163
    • 70349089224 scopus 로고    scopus 로고
    • Simultaneous quantitative analysis of nacylethanolamides in clinical samples
    • Ozalp, A.; Barroso, B. Simultaneous quantitative analysis of nacylethanolamides in clinical samples. Anal. Biochem., 2009, 395(1), 68-76.
    • (2009) Anal Biochem , vol.395 , Issue.1 , pp. 68-76
    • Ozalp, A.1    Barroso, B.2
  • 164
    • 65249103959 scopus 로고    scopus 로고
    • Development and validation of a quantitative method for the determination of 12 endocannabinoids and related compounds in human plasma using liquid chromatography-tandem mass spectrometry
    • Balvers, M.G.J.; Verhoeckx, K.C.M.; Witkamp, R.F. Development and validation of a quantitative method for the determination of 12 endocannabinoids and related compounds in human plasma using liquid chromatography-tandem mass spectrometry. J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci., 2009, 877(14-15), 1583-1590.
    • (2009) J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci , vol.877 , Issue.14-15 , pp. 1583-1590
    • Balvers, M.G.J.1    Verhoeckx, K.C.M.2    Witkamp, R.F.3
  • 165
    • 79952299578 scopus 로고    scopus 로고
    • Central and peripheral endocannabinoids and cognate acylethanolamides in humans: Association with race, adiposity, and energy expenditure
    • Jumpertz, R.; Guijarro, A.; Pratley, R.E.; Piomelli, D.; Krakoff, J. Central and peripheral endocannabinoids and cognate acylethanolamides in humans: association with race, adiposity, and energy expenditure. J. Clin. Endocrinol. Metab., 2011, 96(3), 787-791.
    • (2011) J. Clin. Endocrinol. Metab , vol.96 , Issue.3 , pp. 787-791
    • Jumpertz, R.1    Guijarro, A.2    Pratley, R.E.3    Piomelli, D.4    Krakoff, J.5
  • 166
    • 79951935233 scopus 로고    scopus 로고
    • LC-MS/MS-ESI method for simultaneous quantitation of three endocannabinoids and its application to rat pharmacokinetic studies
    • Sharma, K.; Singh, R.R.; Kandaswamy, M.; Mithra, C.; Giri, S.; Rajagopal, S.; Mullangi, R. LC-MS/MS-ESI method for simultaneous quantitation of three endocannabinoids and its application to rat pharmacokinetic studies. Bioanalysis, 2011, 3(2), 181-196.
    • (2011) Bioanalysis , vol.3 , Issue.2 , pp. 181-196
    • Sharma, K.1    Singh, R.R.2    Kandaswamy, M.3    Mithra, C.4    Giri, S.5    Rajagopal, S.6    Mullangi, R.7
  • 167
    • 0032488797 scopus 로고    scopus 로고
    • Isotope dilution GC/MS determination of anandamide and other fatty acylethanolamides in rat blood plasma
    • Giuffrida, A.; Piomelli, D. Isotope dilution GC/MS determination of anandamide and other fatty acylethanolamides in rat blood plasma. FEBS Lett., 1998, 422(3), 373-376.
    • (1998) FEBS Lett , vol.422 , Issue.3 , pp. 373-376
    • Giuffrida, A.1    Piomelli, D.2
  • 169
    • 1442348425 scopus 로고    scopus 로고
    • Massive accumulation of N-acylethanolamines after stroke. Cell signalling in acute cerebral ischemia
    • Berger, C.; Schmid, P.C.; Schabitz, W.R.; Wolf, M.; Schwab, S.; Schmid, H.H. Massive accumulation of N-acylethanolamines after stroke. Cell signalling in acute cerebral ischemia? J. Neurochem., 2004, 88(5), 1159-1167.
    • (2004) J. Neurochem , vol.88 , Issue.5 , pp. 1159-1167
    • Berger, C.1    Schmid, P.C.2    Schabitz, W.R.3    Wolf, M.4    Schwab, S.5    Schmid, H.H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.