메뉴 건너뛰기




Volumn 23, Issue 7, 2011, Pages 591-600

Palmitoylethanolamide Stimulation Induces Allopregnanolone Synthesis in C6 Cells and Primary Astrocytes: Involvement of Peroxisome-Proliferator Activated Receptor-α

Author keywords

Allopregnanolone; Astrocyte; Palmitoylethanolamide; Peroxisome proliferator activated receptor

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; BUTHIONINE SULFOXIMINE; CYTOCHROME P450; FINASTERIDE; GW 6471; NEUROSTEROID; PALMIDROL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA ANTAGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ANTAGONIST; STEROIDOGENIC ACUTE REGULATORY PROTEIN; UNCLASSIFIED DRUG;

EID: 79959254383     PISSN: 09538194     EISSN: 13652826     Source Type: Journal    
DOI: 10.1111/j.1365-2826.2011.02152.x     Document Type: Article
Times cited : (46)

References (59)
  • 1
    • 78651171367 scopus 로고
    • Fatty acid amides of ethanolamine in mammalian tissues
    • Bachur NR, Masek K, Melmon KL, Udenfriend S. Fatty acid amides of ethanolamine in mammalian tissues. J Biol Chem 1965; 240: 1019-1024.
    • (1965) J Biol Chem , vol.240 , pp. 1019-1024
    • Bachur, N.R.1    Masek, K.2    Melmon, K.L.3    Udenfriend, S.4
  • 2
    • 0029870716 scopus 로고    scopus 로고
    • The ALIAmide palmitoylethanolamide and cannabinoids, but not anandamide, are protective in a delayed postglutamate paradigm of excitotoxic death in cerebellar granule neurons
    • Skaper SD, Buriani A, Dal Toso R, Petrelli L, Romanello S, Facci L, Leon A. The ALIAmide palmitoylethanolamide and cannabinoids, but not anandamide, are protective in a delayed postglutamate paradigm of excitotoxic death in cerebellar granule neurons. Proc Natl Acad Sci USA 1996; 93: 3984-3989.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 3984-3989
    • Skaper, S.D.1    Buriani, A.2    Dal Toso, R.3    Petrelli, L.4    Romanello, S.5    Facci, L.6    Leon, A.7
  • 3
    • 0032537734 scopus 로고    scopus 로고
    • Control of pain initiation by endogenous cannabinoids
    • Calignano A, La Rana G, Giuffrida A, Piomelli D. Control of pain initiation by endogenous cannabinoids. Nature 1998; 394: 277-281.
    • (1998) Nature , vol.394 , pp. 277-281
    • Calignano, A.1    La Rana, G.2    Giuffrida, A.3    Piomelli, D.4
  • 4
    • 0035060264 scopus 로고    scopus 로고
    • Anticonvulsant activity of N-palmitoylethanolamide, a putative endocannabinoid, in mice
    • Lambert DM, Vandevoorde S, Diependaele G, Govaerts SJ, Robert AR. Anticonvulsant activity of N-palmitoylethanolamide, a putative endocannabinoid, in mice. Epilepsia 2001; 42: 321-327.
    • (2001) Epilepsia , vol.42 , pp. 321-327
    • Lambert, D.M.1    Vandevoorde, S.2    Diependaele, G.3    Govaerts, S.J.4    Robert, A.R.5
  • 5
    • 11244328917 scopus 로고    scopus 로고
    • The nuclear receptor peroxisome proliferator-activated receptor-alpha mediates the anti-inflammatory actions of palmitoylethanolamide
    • Lo Verme J, Fu J, Astarita G, La Rana G, Russo R, Calignano A, Piomelli D. The nuclear receptor peroxisome proliferator-activated receptor-alpha mediates the anti-inflammatory actions of palmitoylethanolamide. Mol Pharmacol 2005; 67: 15-19.
    • (2005) Mol Pharmacol , vol.67 , pp. 15-19
    • Lo Verme, J.1    Fu, J.2    Astarita, G.3    La Rana, G.4    Russo, R.5    Calignano, A.6    Piomelli, D.7
  • 6
    • 0031033841 scopus 로고    scopus 로고
    • Occurrence and biosynthesis of endogenous cannabinoid precursor, N-arachidonoyl phosphatidylethanolamine, in rat brain
    • Cadas H, di Tomaso E, Piomelli D. Occurrence and biosynthesis of endogenous cannabinoid precursor, N-arachidonoyl phosphatidylethanolamine, in rat brain. J Neurosci 1997; 17: 1226-1242.
    • (1997) J Neurosci , vol.17 , pp. 1226-1242
    • Cadas, H.1    di Tomaso, E.2    Piomelli, D.3
  • 7
    • 0029117083 scopus 로고
    • Glutamate stimulates the formation of N-acylphosphatidylethanolamine and N-acylethanolamine in cortical neurons in culture
    • Hansen HS, Lauritzen L, Strand AM, Moesgaard B, Frandsen A. Glutamate stimulates the formation of N-acylphosphatidylethanolamine and N-acylethanolamine in cortical neurons in culture. Biochim Biophys Acta 1995; 1258: 303-308.
    • (1995) Biochim Biophys Acta , vol.1258 , pp. 303-308
    • Hansen, H.S.1    Lauritzen, L.2    Strand, A.M.3    Moesgaard, B.4    Frandsen, A.5
  • 8
    • 0042320663 scopus 로고    scopus 로고
    • Palmitoylethanolamide increases after focal cerebral ischemia and potentiates microglial cell motility
    • Franklin A, Parmentier-Batteur S, Walter L, Greenberg DA, Stella N. Palmitoylethanolamide increases after focal cerebral ischemia and potentiates microglial cell motility. J Neurosci 2003; 23: 7767-7775.
    • (2003) J Neurosci , vol.23 , pp. 7767-7775
    • Franklin, A.1    Parmentier-Batteur, S.2    Walter, L.3    Greenberg, D.A.4    Stella, N.5
  • 9
    • 1442348425 scopus 로고    scopus 로고
    • Massive accumulation of N-acylethanolamines after stroke. Cell signalling in acute cerebral ischemia?
    • Berger C, Schmid PC, Schabitz WR, Wolf M, Schwab S, Schmid HH. Massive accumulation of N-acylethanolamines after stroke. Cell signalling in acute cerebral ischemia?. J Neurochem 2004; 88: 1159-1167.
    • (2004) J Neurochem , vol.88 , pp. 1159-1167
    • Berger, C.1    Schmid, P.C.2    Schabitz, W.R.3    Wolf, M.4    Schwab, S.5    Schmid, H.H.6
  • 10
    • 19444386886 scopus 로고    scopus 로고
    • Involvement of the cannabimimetic compound, N-palmitoyl-ethanolamine, in inflammatory and neuropathic conditions: review of the available pre-clinicaldata, and first human studies
    • Darmani NA, Izzo AA, Degenhardt B, Valenti M, Scaglione G, Capasso R, Sorrentini I, Di Marzo V. Involvement of the cannabimimetic compound, N-palmitoyl-ethanolamine, in inflammatory and neuropathic conditions: review of the available pre-clinicaldata, and first human studies. Neuropharmacology 2005; 48: 1154-1163.
    • (2005) Neuropharmacology , vol.48 , pp. 1154-1163
    • Darmani, N.A.1    Izzo, A.A.2    Degenhardt, B.3    Valenti, M.4    Scaglione, G.5    Capasso, R.6    Sorrentini, I.7    Di Marzo, V.8
  • 11
    • 5344277612 scopus 로고    scopus 로고
    • Selective antiepileptic effects of N-palmitoylethanolamide, a putative endocannabinoid
    • Sheerin AH, Zhang X, Saucier DM, Corcoran ME. Selective antiepileptic effects of N-palmitoylethanolamide, a putative endocannabinoid. Epilepsia 2004; 45: 1184-1188.
    • (2004) Epilepsia , vol.45 , pp. 1184-1188
    • Sheerin, A.H.1    Zhang, X.2    Saucier, D.M.3    Corcoran, M.E.4
  • 15
    • 33846623798 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors as transcriptional nodal points and therapeutic targets
    • Brown JD, Plutzky J. Peroxisome proliferator-activated receptors as transcriptional nodal points and therapeutic targets. Circulation 2007; 115: 518-533.
    • (2007) Circulation , vol.115 , pp. 518-533
    • Brown, J.D.1    Plutzky, J.2
  • 17
    • 0028587764 scopus 로고
    • Localization of the peroxisome proliferator-activated receptor in the brain
    • Kainu T, Wikström AC, Gustafsson JA, Pelto-Huikko M. Localization of the peroxisome proliferator-activated receptor in the brain. Neuroreport 1994; 5: 2481-2485.
    • (1994) Neuroreport , vol.5 , pp. 2481-2485
    • Kainu, T.1    Wikström, A.C.2    Gustafsson, J.A.3    Pelto-Huikko, M.4
  • 18
    • 0345118108 scopus 로고    scopus 로고
    • Immunolocalization of peroxisome proliferator-activated receptors and retinoid X receptors in the adult rat CNS
    • Moreno S, Farioli-Vecchioli S, Cerù MP. Immunolocalization of peroxisome proliferator-activated receptors and retinoid X receptors in the adult rat CNS. Neuroscience 2004; 123: 131-145.
    • (2004) Neuroscience , vol.123 , pp. 131-145
    • Moreno, S.1    Farioli-Vecchioli, S.2    Cerù, M.P.3
  • 19
    • 0032052288 scopus 로고    scopus 로고
    • Steroid hormone receptors and steroid action in rat glial cells of the central and peripheral nervous system
    • Jung-Testas I, Baulieu EE. Steroid hormone receptors and steroid action in rat glial cells of the central and peripheral nervous system. J Steroid Biochem Mol Biol 1998; 65: 243-251.
    • (1998) J Steroid Biochem Mol Biol , vol.65 , pp. 243-251
    • Jung-Testas, I.1    Baulieu, E.E.2
  • 20
    • 0031740349 scopus 로고    scopus 로고
    • Steroidogenic acute regulatory protein (StAR) transcripts constitutively expressed in the adult rat central nervous system: colocalization of StAR, cytochrome P-450SCC (CYP XIA1), and 3beta-hydroxysteroid dehydrogenase in the rat brain
    • Furukawa A, Miyatake A, Ohnishi T, Ichikawa Y. Steroidogenic acute regulatory protein (StAR) transcripts constitutively expressed in the adult rat central nervous system: colocalization of StAR, cytochrome P-450SCC (CYP XIA1), and 3beta-hydroxysteroid dehydrogenase in the rat brain. J Neurochem 1998; 71: 2231-2238.
    • (1998) J Neurochem , vol.71 , pp. 2231-2238
    • Furukawa, A.1    Miyatake, A.2    Ohnishi, T.3    Ichikawa, Y.4
  • 23
    • 0028284568 scopus 로고
    • The mitochondrial environment is required for activity of the cholesterol side-chain cleavage enzyme, cytochrome P450scc
    • Black SM, Harikrishna JA, Szklarz GD, Miller WL. The mitochondrial environment is required for activity of the cholesterol side-chain cleavage enzyme, cytochrome P450scc. Proc Natl Acad Sci USA 1994; 91: 7247-7251.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7247-7251
    • Black, S.M.1    Harikrishna, J.A.2    Szklarz, G.D.3    Miller, W.L.4
  • 24
    • 0035047848 scopus 로고    scopus 로고
    • StAR protein and the regulation of steroid hormone biosynthesis
    • Stocco DM. StAR protein and the regulation of steroid hormone biosynthesis. Annu Rev Physiol 2001; 63: 193-213.
    • (2001) Annu Rev Physiol , vol.63 , pp. 193-213
    • Stocco, D.M.1
  • 25
    • 0036936614 scopus 로고    scopus 로고
    • PBR, StAR, and PKA: partners in cholesterol transport in steroidogenic cells
    • Hauet T, Liu J, Li H, Gazouli M, Culty M, Papadopoulos V. PBR, StAR, and PKA: partners in cholesterol transport in steroidogenic cells. Endocr Res 2002; 28: 395-401.
    • (2002) Endocr Res , vol.28 , pp. 395-401
    • Hauet, T.1    Liu, J.2    Li, H.3    Gazouli, M.4    Culty, M.5    Papadopoulos, V.6
  • 26
    • 34548563903 scopus 로고    scopus 로고
    • Neurosteroid regulation of central nervous system development
    • Mellon SH. Neurosteroid regulation of central nervous system development. Pharmacol Ther 2007; 116: 107-124.
    • (2007) Pharmacol Ther , vol.116 , pp. 107-124
    • Mellon, S.H.1
  • 28
    • 0036133869 scopus 로고    scopus 로고
    • Neurosteroids: biochemistry and clinical significance
    • Mellon SH, Griffin LD. Neurosteroids: biochemistry and clinical significance. Trends Endocrinol Metab 2002; 13: 35-43.
    • (2002) Trends Endocrinol Metab , vol.13 , pp. 35-43
    • Mellon, S.H.1    Griffin, L.D.2
  • 29
    • 0742287913 scopus 로고    scopus 로고
    • Production of 5alpha-reduced neurosteroids is developmentally regulated and shapes GABA(A) miniature IPSCs in lamina II of the spinal cord
    • Keller AF, Breton JD, Schlicnter R, Poisbeau P. Production of 5alpha-reduced neurosteroids is developmentally regulated and shapes GABA(A) miniature IPSCs in lamina II of the spinal cord. J Neurosci 2004; 24: 907-915.
    • (2004) J Neurosci , vol.24 , pp. 907-915
    • Keller, A.F.1    Breton, J.D.2    Schlicnter, R.3    Poisbeau, P.4
  • 31
    • 21744447595 scopus 로고    scopus 로고
    • Neurosteroids: endogenous regulators of the GABA(A) receptor
    • Belelli D, Lambert JJ. Neurosteroids: endogenous regulators of the GABA(A) receptor. Nat Rev Neurosci 2005; 6: 565-575.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 565-575
    • Belelli, D.1    Lambert, J.J.2
  • 32
    • 33644944116 scopus 로고    scopus 로고
    • Anti-apoptotic effects of allopregnanolone on P19 neurons
    • Xilouri M, Papazafiri P. Anti-apoptotic effects of allopregnanolone on P19 neurons. Eur J Neurosci 2006; 23: 43-54.
    • (2006) Eur J Neurosci , vol.23 , pp. 43-54
    • Xilouri, M.1    Papazafiri, P.2
  • 33
    • 49049094202 scopus 로고    scopus 로고
    • Antinociceptive profile of ring A-reduced progesterone metabolites in the formalin test
    • Ocvirk R, Pearson Murphy BE, Franklin KB, Abbott FV. Antinociceptive profile of ring A-reduced progesterone metabolites in the formalin test. Pain 2008; 138: 402-409.
    • (2008) Pain , vol.138 , pp. 402-409
    • Ocvirk, R.1    Pearson Murphy, B.E.2    Franklin, K.B.3    Abbott, F.V.4
  • 35
    • 0344492735 scopus 로고    scopus 로고
    • Dehydroepiandrosterone, pregnenolone and sex steroids down-regulate reactive astroglia in the male rat brain after a penetrating brain injury
    • García-Estrada J, Luquín S, Fernández AM, Garcia-Segura LM. Dehydroepiandrosterone, pregnenolone and sex steroids down-regulate reactive astroglia in the male rat brain after a penetrating brain injury. Int J Dev Neurosci 1999; 17: 145-151.
    • (1999) Int J Dev Neurosci , vol.17 , pp. 145-151
    • García-Estrada, J.1    Luquín, S.2    Fernández, A.M.3    Garcia-Segura, L.M.4
  • 37
  • 39
    • 0032890006 scopus 로고    scopus 로고
    • Identification and functional characterization of the mannose receptor in astrocytes
    • Burudi EME, Riese S, Stahl PD, Regnier-Vigouroux A. Identification and functional characterization of the mannose receptor in astrocytes. Glia 1999; 25: 44-55.
    • (1999) Glia , vol.25 , pp. 44-55
    • Burudi, E.M.E.1    Riese, S.2    Stahl, P.D.3    Regnier-Vigouroux, A.4
  • 40
    • 0022895277 scopus 로고
    • Transport into mitochondria and intramitochondrial sorting of the Fe/S protein of ubiquinol-cytochrome c reductase
    • Hartl FU, Schmidt B, Wachter E, Weiss H, Neupert W. Transport into mitochondria and intramitochondrial sorting of the Fe/S protein of ubiquinol-cytochrome c reductase. Cell 1986; 47: 939-951.
    • (1986) Cell , vol.47 , pp. 939-951
    • Hartl, F.U.1    Schmidt, B.2    Wachter, E.3    Weiss, H.4    Neupert, W.5
  • 41
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloro-form extraction
    • Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloro-form extraction. Anal Biochem 1987; 162: 156-159.
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 42
    • 0024804284 scopus 로고
    • Message amplication phenotyping: a technique to simultaneously measure multiple mRNAs from small numbers of cells
    • Brenner CA, Tam AW, Nelson PA, Engelman EG, Susuki N, Fry KE, Larrick JW. Message amplication phenotyping: a technique to simultaneously measure multiple mRNAs from small numbers of cells. BioTechniques 1989; 7: 1096-1103.
    • (1989) BioTechniques , vol.7 , pp. 1096-1103
    • Brenner, C.A.1    Tam, A.W.2    Nelson, P.A.3    Engelman, E.G.4    Susuki, N.5    Fry, K.E.6    Larrick, J.W.7
  • 43
    • 0034544581 scopus 로고    scopus 로고
    • Quantification of neurosteroids in rat plasma and brain following swim stress and allopregnanolone administration using negative chemical ionization gas chromatography/mass spectrometry
    • Vallée M, Rivera JD, Koob GF, Purdy RH, Fitzgerald RL. Quantification of neurosteroids in rat plasma and brain following swim stress and allopregnanolone administration using negative chemical ionization gas chromatography/mass spectrometry. Anal Biochem 2000; 287: 153-166.
    • (2000) Anal Biochem , vol.287 , pp. 153-166
    • Vallée, M.1    Rivera, J.D.2    Koob, G.F.3    Purdy, R.H.4    Fitzgerald, R.L.5
  • 44
    • 0025142672 scopus 로고
    • Malondialdehyde determination as index of lipid peroxidation
    • Draper HH, Hadley M. Malondialdehyde determination as index of lipid peroxidation. Methods Enzymol 1990; 186: 421-431.
    • (1990) Methods Enzymol , vol.186 , pp. 421-431
    • Draper, H.H.1    Hadley, M.2
  • 45
    • 12244283093 scopus 로고    scopus 로고
    • The steroidogenic acute regulatory protein, StAR, works only at the outer mitochondrial membrane
    • Bose HS, Lingappa VR, Miller WL. The steroidogenic acute regulatory protein, StAR, works only at the outer mitochondrial membrane. Endocr Res 2002; 28: 295-308.
    • (2002) Endocr Res , vol.28 , pp. 295-308
    • Bose, H.S.1    Lingappa, V.R.2    Miller, W.L.3
  • 46
    • 45549092520 scopus 로고    scopus 로고
    • Progesterone pretreatment enhances serotonin-stimulated BDNF gene expression in rat c6 glioma cells through production of 5alpha-reduced neurosteroids
    • Morita K, Her S. Progesterone pretreatment enhances serotonin-stimulated BDNF gene expression in rat c6 glioma cells through production of 5alpha-reduced neurosteroids. J Mol Neurosci 2008; 34: 193-200.
    • (2008) J Mol Neurosci , vol.34 , pp. 193-200
    • Morita, K.1    Her, S.2
  • 47
    • 35048894916 scopus 로고    scopus 로고
    • Steroidogenic acute regulatory protein expression and pregnenolone synthesis in rat astrocyte cultures
    • Karry S, Dertien JS, Stocco DM, Syapin PJ. Steroidogenic acute regulatory protein expression and pregnenolone synthesis in rat astrocyte cultures. J Neuroendocrinol 2007; 19: 860-869.
    • (2007) J Neuroendocrinol , vol.19 , pp. 860-869
    • Karry, S.1    Dertien, J.S.2    Stocco, D.M.3    Syapin, P.J.4
  • 49
    • 0027343539 scopus 로고
    • Steroid hormones and neuronal regeneration
    • De Nicola AF. Steroid hormones and neuronal regeneration. Adv Neurol 1993; 59: 199-206.
    • (1993) Adv Neurol , vol.59 , pp. 199-206
    • De Nicola, A.F.1
  • 50
    • 4544282704 scopus 로고    scopus 로고
    • Progesterone and allopregnanolone reduce inflammatory cytokines after traumatic brain injury
    • He J, Evans CO, Hoffman SW, Oyesiku NM, Stein DG. Progesterone and allopregnanolone reduce inflammatory cytokines after traumatic brain injury. Exp Neurol 2004; 189: 404-412.
    • (2004) Exp Neurol , vol.189 , pp. 404-412
    • He, J.1    Evans, C.O.2    Hoffman, S.W.3    Oyesiku, N.M.4    Stein, D.G.5
  • 51
    • 0347418151 scopus 로고    scopus 로고
    • Allopregnanolone and progesterone decrease cell death and cognitive deficits after a contusion of the rat pre-frontal cortex
    • Djebaili M, Hoffman SW, Stein DJ. Allopregnanolone and progesterone decrease cell death and cognitive deficits after a contusion of the rat pre-frontal cortex. Neuroscience 2004; 123: 349-359.
    • (2004) Neuroscience , vol.123 , pp. 349-359
    • Djebaili, M.1    Hoffman, S.W.2    Stein, D.J.3
  • 52
    • 0036444181 scopus 로고    scopus 로고
    • Progesterone protects against necrotic damage and behavioral abnormalities caused by traumatic brain injury
    • Shear DA, Galani R, Hoffman SW, Stein DG. Progesterone protects against necrotic damage and behavioral abnormalities caused by traumatic brain injury. Exp Neurol 2002; 178: 59-67.
    • (2002) Exp Neurol , vol.178 , pp. 59-67
    • Shear, D.A.1    Galani, R.2    Hoffman, S.W.3    Stein, D.G.4
  • 55
    • 74349084448 scopus 로고    scopus 로고
    • The neuroprotective properties of palmitoylethanolamine against oxidative stress in a neuronal cell line
    • Duncan RS, Chapman KD, Koulen P. The neuroprotective properties of palmitoylethanolamine against oxidative stress in a neuronal cell line. Mol Neurodegener 2009; 4: 50.
    • (2009) Mol Neurodegener , vol.4 , pp. 50
    • Duncan, R.S.1    Chapman, K.D.2    Koulen, P.3
  • 57
    • 0033102636 scopus 로고    scopus 로고
    • Glutathione depletion induces giant DNA and high-molecular-weight DNA fragmentation associated with apoptosis through lipid peroxidation and protein kinase C activation in C6 glioma cells
    • Higuchi Y, Matsukawa S. Glutathione depletion induces giant DNA and high-molecular-weight DNA fragmentation associated with apoptosis through lipid peroxidation and protein kinase C activation in C6 glioma cells. Arch Biochem Biophys 1999; 363: 33-42.
    • (1999) Arch Biochem Biophys , vol.363 , pp. 33-42
    • Higuchi, Y.1    Matsukawa, S.2
  • 58
    • 78650353488 scopus 로고    scopus 로고
    • Midazolam inhibits hippocampal long-term potentiation and learning through dual central and peripheral benzodiazepine receptor activation and neurosteroidogenesis
    • Tokuda K, O'Dell KA, Izumi Y, Zorumski CF. Midazolam inhibits hippocampal long-term potentiation and learning through dual central and peripheral benzodiazepine receptor activation and neurosteroidogenesis. J Neurosci 2010; 30: 16788-16795.
    • (2010) J Neurosci , vol.30 , pp. 16788-16795
    • Tokuda, K.1    O'Dell, K.A.2    Izumi, Y.3    Zorumski, C.F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.