High glucose induction of DNA-binding activity of the transcription factor NFκB in patients with diabetic nephropathy

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1782, Issue 5, 2008, Pages 295-302

  Yang, Bingmei ^a   Hodgkinson, Andrea ^a   Oates, Peter J ^b   Millward, Beverley A ^a   Demaine, Andrew G ^a  

^a PENINSULA MEDICAL SCHOOL   (United Kingdom)

^b PFIZER INC   (United States)

Author keywords

Aldose reductase; Aldose reductase inhibitor; Diabetic nephropathy; Nuclear factor kappa B; siRNA

Indexed keywords

ALDEHYDE REDUCTASE; ALDOSE REDUCTASE INHIBITOR; DNA; GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUCIFERASE; SYNAPTOTAGMIN I; TRANSCRIPTION FACTOR;

ADULT; AGED; ARTICLE; BINDING AFFINITY; CAUCASIAN; CELL CULTURE; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DNA BINDING; EMBRYO; ENZYME ASSAY; FEMALE; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; MALE; PATHOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADULT; AGED; AGED, 80 AND OVER; ALDEHYDE REDUCTASE; AMINO ACID MOTIFS; BASE SEQUENCE; BLOTTING, WESTERN; DIABETIC NEPHROPATHIES; DNA; ENZYME INHIBITORS; FEMALE; GENE SILENCING; GLUCOSE; HUMANS; I-KAPPA B PROTEINS; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; NF-KAPPA B; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; TRANSCRIPTION, GENETIC;

EID: 42749093061     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2008.01.009     Document Type: Article

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