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Volumn 91, Issue 4, 2006, Pages 1508-1512

Increased activation of nuclear factor κB triggers inflammation and insulin resistance in polycystic ovary syndrome

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TESTOSTERONE; ANDROSTENEDIONE; GLUCOSE; I KAPPA B; ONCOPROTEIN;

EID: 33646056139     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2005-2327     Document Type: Article
Times cited : (205)

References (31)
  • 1
    • 30344440819 scopus 로고    scopus 로고
    • Reactive oxygen species-induced oxidative stress in the development of insulin resistance and hyperandrogenism in polycystic ovary syndrome
    • González F, Rote NS, Minium J, Kirwan JP 2006 Reactive oxygen species-induced oxidative stress in the development of insulin resistance and hyperandrogenism in polycystic ovary syndrome. J Clin Endocrinol Metab 91:336-340
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 336-340
    • González, F.1    Rote, N.S.2    Minium, J.3    Kirwan, J.P.4
  • 2
    • 0035174615 scopus 로고    scopus 로고
    • The transcription factor NFκB and human disease
    • Baldwin Jr AS 2001 The transcription factor NFκB and human disease. J Clin Invest 107:3-6
    • (2001) J Clin Invest , vol.107 , pp. 3-6
    • Baldwin Jr., A.S.1
  • 3
    • 0034746919 scopus 로고    scopus 로고
    • NFκB: A key role in inflammatory diseases
    • Tak PP, Firestein GS 2001 NFκB: a key role in inflammatory diseases. J Clin Invest 107:7-11
    • (2001) J Clin Invest , vol.107 , pp. 7-11
    • Tak, P.P.1    Firestein, G.S.2
  • 4
    • 0036796875 scopus 로고    scopus 로고
    • Oxidative stress and stress-activated signaling pathways: A unifying hypothesis of type 2 diabetes
    • Evans JL, Goldfine ID, Maddux BA, Grodsky GM 2002 Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. Endocr Rev 23:599-622
    • (2002) Endocr Rev , vol.23 , pp. 599-622
    • Evans, J.L.1    Goldfine, I.D.2    Maddux, B.A.3    Grodsky, G.M.4
  • 5
    • 0030615201 scopus 로고    scopus 로고
    • Nuclear factor-κB: A pivotal transcription factor in chronic inflammatory diseases
    • Barnes PJ, Karin M 1997 Nuclear factor-κB: a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med 336:1066-1071
    • (1997) N Engl J Med , vol.336 , pp. 1066-1071
    • Barnes, P.J.1    Karin, M.2
  • 8
    • 0032936968 scopus 로고    scopus 로고
    • Elevated serum levels of tumor necrosis factor α in normal-weight women with polycystic ovary syndrome
    • González F, Thusu K, Rahman EH, Tomani M, Dandona P 1999 Elevated serum levels of tumor necrosis factor α in normal-weight women with polycystic ovary syndrome. Metabolism 48:437-441
    • (1999) Metabolism , vol.48 , pp. 437-441
    • González, F.1    Thusu, K.2    Rahman, E.H.3    Tomani, M.4    Dandona, P.5
  • 9
    • 24344501691 scopus 로고    scopus 로고
    • Hyperglycemia alters tumor necrosis factor-α release from mononuclear cells in women with polycystic ovary syndrome
    • González F, Minium J, Rote NS, Kirwan JP 2005 Hyperglycemia alters tumor necrosis factor-α release from mononuclear cells in women with polycystic ovary syndrome. J Clin Endocrinol Metab 90:5336-5342
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 5336-5342
    • González, F.1    Minium, J.2    Rote, N.S.3    Kirwan, J.P.4
  • 10
    • 0346725827 scopus 로고    scopus 로고
    • Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome
    • The Rotterdam ESHRE/ASRM-Sponsored PCOS Conference Workshop Group 2004 Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril 81:19-25
    • (2004) Fertil Steril , vol.81 , pp. 19-25
  • 11
    • 0032821965 scopus 로고    scopus 로고
    • Insulin sensitivity indices obtained from oral glucose tolerance testing
    • Matsuda M, DeFronzo R 1999 Insulin sensitivity indices obtained from oral glucose tolerance testing. Diabetes Care 22:1462-1470
    • (1999) Diabetes Care , vol.22 , pp. 1462-1470
    • Matsuda, M.1    DeFronzo, R.2
  • 12
    • 0031974738 scopus 로고    scopus 로고
    • Body mass index, waist girth, and waist to hip ratio as indexes of total and regional adiposity in women: Evaluation using receiver operating characteristic curves
    • Taylor RW, Keil D, Gold EJ, Williams SM, Goulding A 1998 Body mass index, waist girth, and waist to hip ratio as indexes of total and regional adiposity in women: evaluation using receiver operating characteristic curves. Am J Clin Nutr 67:44-49
    • (1998) Am J Clin Nutr , vol.67 , pp. 44-49
    • Taylor, R.W.1    Keil, D.2    Gold, E.J.3    Williams, S.M.4    Goulding, A.5
  • 13
    • 0036364372 scopus 로고    scopus 로고
    • Activation of nuclear factor-κB (NFκB) in mononuclear cells
    • Aljada A, Ghanim H, Dandona P 2002 Activation of nuclear factor-κB (NFκB) in mononuclear cells. Methods Mol Biol 196:105-110
    • (2002) Methods Mol Biol , vol.196 , pp. 105-110
    • Aljada, A.1    Ghanim, H.2    Dandona, P.3
  • 14
    • 0036369592 scopus 로고    scopus 로고
    • Translocation of p47phox and activation of NADPH oxidase in mononuclear cells
    • Aljada A, Ghanim H, Dandona P 2002 Translocation of p47phox and activation of NADPH oxidase in mononuclear cells. Methods Mol Biol 196:99-103
    • (2002) Methods Mol Biol , vol.196 , pp. 99-103
    • Aljada, A.1    Ghanim, H.2    Dandona, P.3
  • 15
    • 1842453995 scopus 로고    scopus 로고
    • Differential effects of glucose and alcohol on reactive oxygen species generation and intranuclear nuclear factor-κB in mononuclear cells
    • Dhindsa S, Tripathy D, Mohanty P, Ghanim H, Syed T, Aljada A, Dandona P 2004 Differential effects of glucose and alcohol on reactive oxygen species generation and intranuclear nuclear factor-κB in mononuclear cells. Metabolism 53:330-334
    • (2004) Metabolism , vol.53 , pp. 330-334
    • Dhindsa, S.1    Tripathy, D.2    Mohanty, P.3    Ghanim, H.4    Syed, T.5    Aljada, A.6    Dandona, P.7
  • 16
    • 0034915177 scopus 로고    scopus 로고
    • Insulin inhibits intranuclear factor κB and stimulates IκB in mononuclear cells in obese subjects: Evidence for an anti-inflammatory effect?
    • Dandona P, Aljada A, Mohanty P, Ghanim H, Hamouda W, Assian E, Ahmad S 2001 Insulin inhibits intranuclear factor κB and stimulates IκB in mononuclear cells in obese subjects: evidence for an anti-inflammatory effect? J Clin Endocrinol Metab 86:3257-3265
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 3257-3265
    • Dandona, P.1    Aljada, A.2    Mohanty, P.3    Ghanim, H.4    Hamouda, W.5    Assian, E.6    Ahmad, S.7
  • 18
    • 30744475727 scopus 로고    scopus 로고
    • Altered tumor necrosis factor-α release from mononuclear cells of obese reproductive-age women during hyperglycemia
    • González F, Minium J, Rote NS, Kirwan JP 2006 Altered tumor necrosis factor-α release from mononuclear cells of obese reproductive-age women during hyperglycemia. Metabolism 55:271-276
    • (2006) Metabolism , vol.55 , pp. 271-276
    • González, F.1    Minium, J.2    Rote, N.S.3    Kirwan, J.P.4
  • 20
  • 21
    • 0036200250 scopus 로고    scopus 로고
    • Both lipid and protein intakes stimulate increased generation of reactive oxygen species by polymorphonuclear leukocytes and mononuclear cells
    • Mohanty P, Ghanim H, Hamouda W, Aljada A, Garg R, Dandona P 2002 Both lipid and protein intakes stimulate increased generation of reactive oxygen species by polymorphonuclear leukocytes and mononuclear cells. Am J Clin Nutr 75:767-772
    • (2002) Am J Clin Nutr , vol.75 , pp. 767-772
    • Mohanty, P.1    Ghanim, H.2    Hamouda, W.3    Aljada, A.4    Garg, R.5    Dandona, P.6
  • 22
    • 0035140336 scopus 로고    scopus 로고
    • The suppressive effect of dietary restriction and weight loss in the obese on the generation of reactive oxygen species by leukocytes, lipid peroxidation, and protein carbonylation
    • Dandona P, Mohanty P, Ghanim H, Aljada A, Browne R, Hamouda W, Prabhala A, Afzal A, Garg R 2001 The suppressive effect of dietary restriction and weight loss in the obese on the generation of reactive oxygen species by leukocytes, lipid peroxidation, and protein carbonylation. J Clin Endocrinol Metab 86:355-362
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 355-362
    • Dandona, P.1    Mohanty, P.2    Ghanim, H.3    Aljada, A.4    Browne, R.5    Hamouda, W.6    Prabhala, A.7    Afzal, A.8    Garg, R.9
  • 23
    • 85047681547 scopus 로고    scopus 로고
    • Inhibitory effect of a two day fast on reactive oxygen species (ROS) generation by leucocytes and plasma ortho-tyrosine and meta-tyrosine concentrations
    • Dandona P, Mohanty P, Hamouda W, Ghanim H, Aljada A, Garg R, Kumar V 2001 Inhibitory effect of a two day fast on reactive oxygen species (ROS) generation by leucocytes and plasma ortho-tyrosine and meta-tyrosine concentrations. J Clin Endocrinol Metab 86:2899-2902
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 2899-2902
    • Dandona, P.1    Mohanty, P.2    Hamouda, W.3    Ghanim, H.4    Aljada, A.5    Garg, R.6    Kumar, V.7
  • 24
    • 0037835471 scopus 로고    scopus 로고
    • Relation of intra-abdominal fat distribution to metabolic disorders in nonobese patients with polycystic ovary syndrome
    • Yildirim B, Sabir N, Kaleli B 2003 Relation of intra-abdominal fat distribution to metabolic disorders in nonobese patients with polycystic ovary syndrome. Fertil Steril 79:1358-1364
    • (2003) Fertil Steril , vol.79 , pp. 1358-1364
    • Yildirim, B.1    Sabir, N.2    Kaleli, B.3
  • 26
    • 2042480671 scopus 로고    scopus 로고
    • Comparison of the release of adiponectin by adipose tissue, adipose tissue matrix, and adipocytes from visceral and subcutaneous abdominal adipose tissues of obese humans
    • Fain JN, Madan AK, Hyler ML, Cheema P, Bahouth SM 2004 Comparison of the release of adiponectin by adipose tissue, adipose tissue matrix, and adipocytes from visceral and subcutaneous abdominal adipose tissues of obese humans. Endocrinology 145:2273-2282
    • (2004) Endocrinology , vol.145 , pp. 2273-2282
    • Fain, J.N.1    Madan, A.K.2    Hyler, M.L.3    Cheema, P.4    Bahouth, S.M.5
  • 28
    • 0029927701 scopus 로고    scopus 로고
    • Localization and characterization of white blood cell populations within the human ovary throughout the menstrual cycle and menopause
    • Best CL, Pudney J, Welch WR, Burger N, Hill JA 1996 Localization and characterization of white blood cell populations within the human ovary throughout the menstrual cycle and menopause. Hum Reprod 11:790-797
    • (1996) Hum Reprod , vol.11 , pp. 790-797
    • Best, C.L.1    Pudney, J.2    Welch, W.R.3    Burger, N.4    Hill, J.A.5
  • 29
    • 30344486599 scopus 로고    scopus 로고
    • Oxidative stress induces expression of CYP11A, CYP17, STAR and 3βHSD in rat theca-interstitial cells
    • Abstract
    • Piotrowski PC, Rzepczynska IJ, Kwintkiewicz J, Duleba AJ 2005 Oxidative stress induces expression of CYP11A, CYP17, STAR and 3βHSD in rat theca-interstitial cells. J Soc Gynecol Invest 12(Suppl 2):319A (Abstract)
    • (2005) J Soc Gynecol Invest , vol.12 , Issue.2 SUPPL.
    • Piotrowski, P.C.1    Rzepczynska, I.J.2    Kwintkiewicz, J.3    Duleba, A.J.4
  • 30
    • 30344437803 scopus 로고    scopus 로고
    • Effect of mevastatin on expression of CYP17, 3βHSD, CYP11A and STAR in rat theca-interstitial cells
    • Abstract
    • Rzepczynska IJ, Piotrowski PC, Kwintkiewicz J, Duleba AJ 2005 Effect of mevastatin on expression of CYP17, 3βHSD, CYP11A and STAR in rat theca-interstitial cells. J Soc Gynecol Invest 12(Suppl 2):320A (Abstract)
    • (2005) J Soc Gynecol Invest , vol.12 , Issue.2 SUPPL.
    • Rzepczynska, I.J.1    Piotrowski, P.C.2    Kwintkiewicz, J.3    Duleba, A.J.4
  • 31
    • 0032880852 scopus 로고    scopus 로고
    • Tumor necrosis factor-α stimulates proliferation of rat ovarian theca-interstitial cells
    • Spazynsky RZ, Arici A, Duleba AJ 1999 Tumor necrosis factor-α stimulates proliferation of rat ovarian theca-interstitial cells. Biol Reprod 61:993-998
    • (1999) Biol Reprod , vol.61 , pp. 993-998
    • Spazynsky, R.Z.1    Arici, A.2    Duleba, A.J.3


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