Biomarkers of exposure and effect in human lymphoblastoid TK6 cells following [13C2]-acetaldehyde exposure

Toxicological Sciences

Volumn 133, Issue 1, 2013, Pages 1-12

  Moeller, Benjamin C ^a   Recio, Leslie ^b   Green, Amanda ^b   Sun, Wei ^c,d   Wright, Fred A ^c   Bodnar, Wanda M ^e   Swenberg, James A ^a,e  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b ILS   (United States)

^c University of North Carolina at Chapel Hill   (United States)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^e University of North Carolina at Chapel Hill   (United States)

Author keywords

Acetaldehyde; Biomarker of effect; Biomarker of exposure; DNA adduct; Liquid chromatography mass spectrometry; Micronucleus

Indexed keywords

ACETALDEHYDE; CARBON 13; DEOXYGUANOSINE; N2 ETHYLIDENE; RADICAL; UNCLASSIFIED DRUG;

ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; DNA ADDUCT; EXPOSURE; HUMAN; HUMAN CELL; ISOTOPE LABELING; LIQUID CHROMATOGRAPHY; LYMPHOBLASTOID CELL; MICRONUCLEUS; STATISTICAL SIGNIFICANCE; TANDEM MASS SPECTROMETRY;

ACETALDEHYDE; ALDEHYDE DEHYDROGENASE; CARBON ISOTOPES; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; CELL SURVIVAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYGUANOSINE; DNA ADDUCTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL EXPOSURE; FLOW CYTOMETRY; GENOTYPE; HUMANS; MICRONUCLEI, CHROMOSOME-DEFECTIVE; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY;

EID: 84876809602     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kft029     Document Type: Article

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