Evaluation of the DNA damaging potential of cannabis cigarette smoke by the determination of acetaldehyde derived N2-ethyl-2′- deoxyguanosine adducts

Chemical Research in Toxicology

Volumn 22, Issue 6, 2009, Pages 1181-1188

  Singh, Rajinder ^a   Sandhu, Jatinderpal ^a   Kaur, Balvinder ^a   Juren, Tina ^b   Steward, William P ^a   Segerbäck, Dan ^b   Farmer, Peter B ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ACETALDEHYDE; CANNABIS; CIGARETTE SMOKE; DNA; N2 ETHYLIDENE 2' DEOXYGUANOSINE; SCHIFF BASE; STABLE ISOTOPE; TOBACCO SMOKE; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; GENOTOXICITY; HUMAN; HUMAN TISSUE; HYDROLYSIS; LIQUID CHROMATOGRAPHY; ONLINE MONITORING; REDUCTION; TANDEM MASS SPECTROMETRY;

ACETALDEHYDE; ADULT; CANNABIS; CARCINOGENS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYGUANOSINE; DNA; DNA ADDUCTS; DNA DAMAGE; HUMANS; LUNG; MALE; MARIJUANA SMOKING; MIDDLE AGED; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

CANNABIS; NICOTIANA TABACUM;

EID: 67449092215     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx900106y     Document Type: Article

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