Combination of ADH1B*2/ALDH2*2 polymorphisms alters acetaldehyde-derived DNA damage in the blood of Japanese alcoholics

Cancer Science

Volumn 103, Issue 9, 2012, Pages 1651-1655

  Yukawa, Yoshiyuki ^a   Muto, Manabu ^a   Hori, Kimiko ^a   Nagayoshi, Haruna ^b   Yokoyama, Akira ^c   Chiba, Tsutomu ^a   Matsuda, Tomonari ^b  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c KURIHAMA NATIONAL HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETALDEHYDE; ALCOHOL DEHYDROGENASE 1B; ALCOHOL DEHYDROGENASE 2; ALDEHYDE DEHYDROGENASE; DEOXYGUANOSINE; N 2 ETHYLIDENE 2' DEOXYGUANOSINE; UNCLASSIFIED DRUG; ADH1B PROTEIN, HUMAN; ALCOHOL DEHYDROGENASE; ALDH2 PROTEIN, HUMAN; DRUG DERIVATIVE; N2 ETHYLIDENE 2' DEOXYGUANOSINE; N2-ETHYLIDENE-2'-DEOXYGUANOSINE;

ADULT; ALCOHOL METABOLISM; ALCOHOLISM; ARTICLE; BLOOD SAMPLING; CANCER RISK; CARCINOGEN DNA INTERACTION; CARCINOGENICITY; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; DNA POLYMORPHISM; ELECTROSPRAY MASS SPECTROMETRY; ESOPHAGUS CANCER; GENOTYPE; HUMAN; HUMAN TISSUE; JAPAN; LIQUID CHROMATOGRAPHY; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; ALLELE; ASIAN; BLOOD; CHEMISTRY; GENETICS; METABOLISM; MIDDLE AGED; SINGLE NUCLEOTIDE POLYMORPHISM;

ACETALDEHYDE; ADULT; ALCOHOL DEHYDROGENASE; ALCOHOLISM; ALDEHYDE DEHYDROGENASE; ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; DEOXYGUANOSINE; DNA ADDUCTS; DNA DAMAGE; GENOTYPE; HUMANS; JAPAN; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84865736067     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2012.02360.x     Document Type: Article

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