Ethanol-mediated carcinogenesis in the human esophagus implicates CYP2E1 induction and the generation of carcinogenic DNA-lesions

International Journal of Cancer

Volumn 128, Issue 3, 2011, Pages 533-540

  Millonig, Gunda ^a   Wang, Ying ^a   Homann, Nils ^b   Bernhardt, Friederike ^b   Qin, Hua ^a   Mueller, Sebastian ^a   Bartsch, Helmut ^c   Seitz, Helmut K ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF LÜBECK   (Germany)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

alcohol; cytochrome P4502E1; DNA adducts; esophageal cancer; oxidative stress

Indexed keywords

1,N6 ETHENOADENOSINE; 3,N4 ETHENODEOXYCYTIDINE; ADENOSINE DERIVATIVE; ALCOHOL; CYTIDINE DERIVATIVE; CYTOCHROME P450 2E1; DNA; KI 67 ANTIGEN; UNCLASSIFIED DRUG;

ADULT; ALCOHOL CONSUMPTION; ALCOHOLISM; ARTICLE; CARCINOGENESIS; CELL PROLIFERATION; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIGESTIVE SYSTEM CANCER; DNA ADDUCT; DNA DAMAGE; ENZYME INDUCTION; ESOPHAGUS BIOPSY; ESOPHAGUS CANCER; ESOPHAGUS MUCOSA; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR BIOPSY;

AGED; ALCOHOL DRINKING; CARCINOGENICITY TESTS; CYTOCHROME P-450 CYP2E1; DNA ADDUCTS; ESOPHAGEAL NEOPLASMS; ETHANOL; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; REFERENCE VALUES; SMOKING;

EID: 78649867714     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.25604     Document Type: Article

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