A review on the role of quinones in renal disorders

SpringerPlus

Volumn 2, Issue 1, 2013, Pages 1-8

  Madeo, Jennifer ^a   Zubair, Adeel ^a   Marianne, Frieri ^a  

^a NASSAU UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Acute kidney injury (AKI); Chronic kidney disease; Co enzyme Q; Nephrotoxic; Proton carriers; Reactive oxygen species (ROS)

Indexed keywords

EID: 84876558995     PISSN: None     EISSN: 21931801     Source Type: Journal    
DOI: 10.1186/2193-1801-2-139     Document Type: Review

References (99)

1. Aksu U, Demirci C, Ince C (2011) The pathogenesis of acute kidney injury and the toxic triangle of oxygen, reactive oxygen species and nitric oxide. Contrib Nephrol 174:119-128
2. Albracht SP, Meijer AJ, Rydstrom J (2011) Mammalian NADH:ubiquinone oxidoreductase (Complex I) and nicotinamide nucleotide transhydrogenase (Nnt) together regulate the mitochondrial production of H(2)O(2)-implications for their role in disease, especially cancer. J Bioenerg Biomembr 43:541-564
3. Ali BH, Al Za'abi M, Blunden G et al (2011) Experimental gentamicin nephrotoxicity and agents that modify it: a mini-review of recent research. Basic Clin Pharmacol Toxicol 109:225-232
4. Alkharfy KM, Al-Daghri NM, Al-Attas OS et al (2011) The protective effect of thymoquinone against sepsis syndrome morbidity and mortality in mice. Int Immunopharmacol 11:250-254
5. Balercia G, Mancini A, Paggi F et al (2009) Coenzyme Q10 and male infertility. J Endocrinol Invest 32:626-632
6. Barisoni L, Kriz W, Mundel P et al (1999) The dysregulated podocyte phenotype: a novel concept in the pathogenesis of collapsing idiopathic focal segmental glomerulosclerosis and HIV-associated nephropathy. J Am Soc Nephrol 10:51-61
7. Basarslan F, Yilmaz N, Ates S et al (2012) Protective effects of thymoquinone on vancomycin-induced nephrotoxicity in rats. Hum Exp Toxicol 31:726-733
8. Begleiter A, Leith MK, Curphey TJ et al (1997) Induction of DT-diaphorase in cancer chemoprevention and chemotherapy. Oncol Res 9:371-382
9. Bolton JL, Trush MA, Penning TM et al (2000) Role of quinones in toxicology. Chem Res Toxicol 13:135-160
10. Boutaud O, Roberts LJ 2nd (2011) Mechanism-based therapeutic approaches to rhabdomyolysis-induced renal failure. Free Radic Biol Med 51:1062-1067
11. Cavalieri E, Rogan E (2006) Catechol quinones of estrogens in the initiation of breast, prostate, and other human cancers: keynote lecture. Ann N Y Acad Sci 1089:286-301
12. Chen M, Gong L, Qi X et al (2011) Inhibition of renal NQO1 activity by dicoumarol suppresses nitroreduction of aristolochic acid I and attenuates its nephrotoxicity. Toxicol Sci 122:288-296
13. De Broe ME (2012) Chinese herbs nephropathy and Balkan endemic nephropathy: toward a single entity, aristolochic acid nephropathy. Kidney Int 81:513-515
14. Dhakshinamoorthy S, Long DJ 2nd, Jaiswal AK (2000) Antioxidant regulation of genes encoding enzymes that detoxify xenobiotics and carcinogens. Curr Top Cell Regul 36:201-216
15. Diomedi-Camassei F, Di Giandomenico S, Santorelli FM et al (2007) COQ2 nephropathy: a newly described inherited mitochondriopathy with primary renal involvement. J Am Soc Nephrol 18:2773-2780
16. Durvasula RV, Shankland SJ (2006) The renin-angiotensin system in glomerular podocytes: mediator of glomerulosclerosis and link to hypertensive nephropathy. Curr Hypertens Rep 8:132-138
17. Eltzschig HK, Eckle T (2011) Ischemia and reperfusion-from mechanism to translation. Nat Med 17:1391-1401
18. Enns GM, Kinsman SL, Perlman SL et al (2012) Initial experience in the treatment of inherited mitochondrial disease with EPI-743. Mol Genet Metab 105:91-102
19. Falk MJ, Polyak E, Zhang Z et al (2011) Probucol ameliorates renal and metabolic sequelae of primary CoQ deficiency in Pdss2 mutant mice. EMBO Mol Med 3:410-427
20. Forbes JM, Coughlan MT, Cooper ME (2008) Oxidative stress as a major culprit in kidney disease in diabetes. Diabetes 57:1446-1454
21. Frieri M (2012) Accelerated atherosclerosis in systemic lupus erythematosus: role of proinflammatory cytokines and therapeutic approaches. Curr Allergy Asthma Rep 12:25-32
22. Frieri M, Samih MA, Dzhindzhikhashvili M et al (2012) Toll-like receptor 9 and vascular endothelial growth factor levels in human kidneys from lupus nephritis patients. Curr Allergy Asthma Rep 25:1041-1046
23. Gao X, Wen X, Esser L et al (2003) Structural basis for the quinone reduction in the bc1 complex: a comparative analysis of crystal structures of mitochondrial cytochrome bc1 with bound substrate and inhibitors at the Qi site. Biochemistry 42:9067-9080
24. Garg P, Holzman LB (2012) Podocytes: gaining a foothold. Exp Cell Res 318:955-963
25. Gobe G, Crane D (2010) Mitochondria, reactive oxygen species and cadmium toxicity in the kidney. Toxicol Lett 198:49-55
26. Gokbel H, Atalay H, Okudan N et al (2011) Coenzyme Q10 and its relation with oxidant and antioxidant system markers in patients with end-stage renal disease. Ren Fail 33:677-681
27. Gorin Y, Ricono JM, Wagner B et al (2004) Angiotensin II-induced ERK1/ERK2 activation and protein synthesis are redox-dependent in glomerular mesangial cells. Biochem J 381:231-239
28. Gunner MR, Madeo J, Zhu Z (2008) Modification of quinone electrochemistry by the proteins in the biological electron transfer chains: examples from photosynthetic reaction centers. J Bioenerg Biomembr 40:509-519
29. Hyson HC, Kieburtz K, Shoulson I et al (2010) Safety and tolerability of highdosage coenzyme Q10 in Huntington's disease and healthy subjects. Mov Disord 25:1924-1928
30. Iverson TM, Arciero DM, Hooper AB et al (2001) High-resolution structures of the oxidized and reduced states of cytochrome c554 from Nitrosomonas europaea. J Biol Inorg Chem 6:390-397
31. Jacquerioz FA, Croft AM (2009) Drugs for preventing malaria in travellers. Cochrane Database Syst Rev 4:CD006491
32. Jamshidi M, Bartkova J, Greco D et al (2012) NQO1 expression correlates inversely with NFkappaB activation in human breast cancer. Breast Cancer Res Treat 132:955-968
33. Jun M, Venkataraman V, Razavian M et al (2012) Antioxidants for chronic kidney disease. Cochrane Database Syst Rev 10, CD008176
34. Kalayci M, Unal MM, Gul S et al (2011) Effect of coenzyme Q10 on ischemia and neuronal damage in an experimental traumatic brain-injury model in rats. BMC Neurosci 12:75
35. Kerr DS (2010) Treatment of mitochondrial electron transport chain disorders: a review of clinical trials over the past decade. Mol Genet Metab 99:246-255
36. Khan MA, Chen HC, Tania M et al (2011) Anticancer activities of Nigella sativa (black cumin). Afr J Tradit Complement Altern Med 8:226-232
37. Kitiyakara C, Chabrashvili T, Chen Y et al (2003) Salt intake, oxidative stress, and renal expression of NADPH oxidase and superoxide dismutase. J Am Soc Nephrol 14:2775-2782
38. Kleiner HE, Rivera MI, Pumford NR et al (1998) Immunochemical detection of quinol-thioether-derived protein adducts. Chem Res Toxicol 11:1283-1290
39. Koyner JL, Sher Ali R, Murray PT (2008) Antioxidants. Do they have a place in the prevention or therapy of acute kidney injury? Nephron Exp Nephrol 109:e109-e117
40. Kretzler M, Schroppel B, Merkle M et al (1998) Detection of multiple vascular endothelial growth factor splice isoforms in single glomerular podocytes. Kidney Int Suppl 67:S159-S161
41. Kunzendorf U, Haase M, Rolver L et al (2010) Novel aspects of pharmacological therapies for acute renal failure. Drugs 70:1099-1114
42. Kurien BT, Scofield RH (2008) Autoimmunity and oxidatively modified autoantigens. Autoimmun Rev 7:567-573
43. Kurisu G, Zhang H, Smith JL et al (2003) Structure of the cytochrome b6f complex of oxygenic photosynthesis: tuning the cavity. Science 302:1009-1014
44. Leigh D (1951) Subacute necrotizing encephalomyelopathy in an infant. J Neurol Neurosurg Psychiatry 14:216-221
45. Lippa S, Colacicco L, Calla C et al (1994) Coenzyme Q10 levels, plasma lipids and peroxidation extent in renal failure and in hemodialytic patients. Mol Aspects Med 15(Suppl):s213-s219
46. Lulli M, Witort E, Papucci L et al (2012) Coenzyme Q10 instilled as eye drops on the cornea reaches the retina and protects retinal layers from apoptosis in a mouse model of kainate-induced retinal damage. Invest Ophthalmol Vis Sci 53:8295-8302
47. Madeo J, Gunner MR (2005) Modeling binding kinetics at the Q(A) site in bacterial reaction centers. Biochemistry 44:10994-11004
48. Madeo J, Mihajlovic M, Lazaridis T et al (2011) Slow dissociation of a charged ligand: analysis of the primary quinone Q(A) site of photosynthetic bacterial reaction centers. J Am Chem Soc 133:17375-17385
49. Marshall CB, Pippin JW, Krofft RD et al (2006) Puromycin aminonucleoside induces oxidant-dependent DNA damage in podocytes in vitro and in vivo. Kidney Int 70:1962-1973
50. McCarty MF, Barroso-Aranda J, Contreras F (2010) Oxidative stress therapy for solid tumors-a proposal. Med Hypotheses 74:1052-1054
51. Mehmetoglu I, Yerlikaya FH, Kurban S et al (2012) Oxidative stress markers in hemodialysis and peritoneal dialysis patients, including coenzyme Q10 and ischemia-modified albumin. Int J Artif Organs 35:226-232
52. Mimaki M, Wang X, McKenzie M et al (1817) Understanding mitochondrial complex I assembly in health and disease. Biochim Biophys Acta 2012:851-862
53. Mitchell T, Saba H, Laakman J et al (2010) Role of mitochondrial-derived oxidants in renal tubular cell cold-storage injury. Free Radic Biol Med 49:1273-1282
54. Mitchell T, Rotaru D, Saba H et al (2011) The mitochondria-targeted antioxidant mitoquinone protects against cold storage injury of renal tubular cells and rat kidneys. J Pharmacol Exp Ther 336:682-692
55. Monks TJ, Jones DC (2002) The metabolism and toxicity of quinones, quinonimines, quinone methides, and quinone-thioethers. Curr Drug Metab 3:425-438
56. Montini G, Malaventura C, Salviati L (2008) Early coenzyme Q10 supplementation in primary coenzyme Q10 deficiency. N Engl J Med 358:2849-2850
57. Morre DJ, Morre DM (2011) Non-mitochondrial coenzyme Q. Biofactors 37:355-360
58. Mukhopadhyay P, Horvath B, Zsengeller Z et al (2012) Mitochondrial-targeted antioxidants represent a promising approach for prevention of cisplatininduced nephropathy. Free Radic Biol Med 52:497-506
59. Nagase M, Matsui H, Shibata S et al (2007) Salt-induced nephropathy in obese spontaneously hypertensive rats via paradoxical activation of the mineralocorticoid receptor: role of oxidative stress. Hypertension 50:877-883
60. Nangaku M (2006) Chronic hypoxia and tubulointerstitial injury: a final common pathway to end-stage renal failure. J Am Soc Nephrol 17:17-25
61. Ogasawara Y, Umezu N, Ishii K (2012) DNA damage in human pleural mesothelial cells induced by exposure to carbon nanotubes. Nihon Eiseigaku Zasshi 67:76-83
62. Okamura DM, Himmelfarb J (2009) Tipping the redox balance of oxidative stress in fibrogenic pathways in chronic kidney disease. Pediatr Nephrol 24:2309-2319
63. Orient A, Donko A, Szabo A et al (2007) Novel sources of reactive oxygen species in the human body. Nephrol Dial Transplant 22:1281-1288
64. Oudemans-van Straaten HM (2005) Strategies to prevent contrast nephropathy. Minerva Cardioangiol 53:445-463
65. Perez-Sanchez C, Ruiz-Limon P, Aguirre MA et al (2012) Mitochondrial dysfunction in antiphospholipid syndrome: implications in the pathogenesis of the disease and effects of coenzyme Q(10) treatment. Blood 119:5859-5870
66. Qu HY, Gao HZ, Hao GT et al (2010) Single-dose safety, pharmacokinetics, and food effects studies of compound naphthoquine phosphate tablets in healthy volunteers. J Clin Pharmacol 50:1310-1318
67. Quinzii CM, Hirano M (2010) Coenzyme Q and mitochondrial disease. Dev Disabil Res Rev 16:183-188
68. Ragheb A, Attia A, Eldin WS et al (2009) The protective effect of thymoquinone, an anti-oxidant and anti-inflammatory agent, against renal injury: a review. Saudi J Kidney Dis Transpl 20:741-752
69. Rakoczi K, Klivenyi P, Vecsei L (2009) Neuroprotection in Parkinson's disease and other neurodegenerative disorders: preclinical and clinical findings. Ideggyogy Sz 62:25-34
70. Ralph SJ, Low P, Dong L et al (2006) Mitocans: mitochondrial targeted anticancer drugs as improved therapies and related patent documents. Recent Pat Anticancer Drug Discov 1:327-346
71. Ralph SJ, Moreno-Sanchez R, Neuzil J et al (2011) Inhibitors of succinate: quinone reductase/Complex II regulate production of mitochondrial reactive oxygen species and protect normal cells from ischemic damage but induce specific cancer cell death. Pharm Res 28:2695-2730
72. Rich PR, Bendall DS (1979) A mechanism for the reduction of cytochromes by quinols in solution and its relevance to biological electron transfer reactions. FEBS Lett 105:189-194
73. Ross D, Kepa JK, Winski SL et al (2000) NAD(P)H:quinone oxidoreductase 1 (NQO1): chemoprotection, bioactivation, gene regulation and genetic polymorphisms. Chem Biol Interact 129:77-97
74. Sagar S, Kaur M, Minneman KP et al (2010) Anti-cancer activities of diospyrin, its derivatives and analogues. Eur J Med Chem 45:3519-3530
75. Sakata T, Furuya R, Shimazu T et al (2008) Coenzyme Q10 administration suppresses both oxidative and antioxidative markers in hemodialysis patients. Blood Purif 26:371-378
76. Sakatsume M, Kadomura M, Sakata I et al (2001) Novel glomerular lipoprotein deposits associated with apolipoprotein E2 homozygosity. Kidney Int 59:1911-1918
77. Salviati L, Sacconi S, Murer L et al (2005) Infantile encephalomyopathy and nephropathy with CoQ10 deficiency: a CoQ10-responsive condition. Neurology 65:606-608
78. Sankaranarayanan C, Pari L (2011) Thymoquinone ameliorates chemical induced oxidative stress and beta-cell damage in experimental hyperglycemic rats. Chem Biol Interact 190:148-154
79. Sayed-Ahmed MM, Nagi MN (2007) Thymoquinone supplementation prevents the development of gentamicin-induced acute renal toxicity in rats. Clin Exp Pharmacol Physiol 34:399-405
80. Siegel D, Yan C, Ross D (2012) NAD(P)H:quinone oxidoreductase 1 (NQO1) in the sensitivity and resistance to antitumor quinones. Biochem Pharmacol 83:1033-1040
81. Singbartl K, Kellum JA (2012) AKI in the ICU: definition, epidemiology, risk stratification, and outcomes. Kidney Int 81:819-825
82. Skulachev VP, Anisimov VN, Antonenko YN et al (2009) An attempt to prevent senescence: a mitochondrial approach. Biochim Biophys Acta 1787:437-461
83. Skulachev MV, Antonenko YN, Anisimov VN et al (2011) Mitochondrial-targeted plastoquinone derivatives. Effect on senescence and acute age-related pathologies. Curr Drug Targets 12:800-826
84. Soares J, Keppler BR, Wang X et al (2011) Ortho-Quinone tanshinones directly inhibit telomerase through an oxidative mechanism mediated by hydrogen peroxide. Bioorg Med Chem Lett 21:7474-7478
85. Stowell MHB, McPhillips TM, Rees DC et al (1997) Light-induced structural changes in photosynthetic reaction center: implications for mechanism of electron-proton transfer. Science 276:812-816
86. Syed S, Zubair A, Frieri M (2012) Immune response to nanomaterials: implications for medicine and literature review. Curr Allergy Asthma Rep 13(1):50-57
87. Tamura Y, Tanabe K, Kitagawa W et al (2012) Nicorandil, a Katp channel opener, alleviates chronic renal injury by targeting podocytes and macrophages. Am J Physiol Renal Physiol 303:F339-F349
88. Thurnherr T, Brandenberger C, Fischer K et al (2011) A comparison of acute and long-term effects of industrial multiwalled carbon nanotubes on human lung and immune cells in vitro. Toxicol Lett 200:176-186
89. Tsai KL, Chen LH, Chiou SH et al (2011) Coenzyme Q10 suppresses oxLDLinduced endothelial oxidative injuries by the modulation of LOX-1-mediated ROS generation via the AMPK/PKC/NADPH oxidase signaling pathway. Mol Nutr Food Res 55(Suppl 2):S227-S240
90. Varagic J, Ahmad S, Brosnihan KB et al (2010) Salt-induced renal injury in spontaneously hypertensive rats: effects of nebivolol. Am J Nephrol 32:557-566
91. Verrax J, Beck R, Dejeans N et al (2011) Redox-active quinones and ascorbate: an innovative cancer therapy that exploits the vulnerability of cancer cells to oxidative stress. Anticancer Agents Med Chem 11:213-221
92. Villalba JM, Parrado C, Santos-Gonzalez M et al (2010) Therapeutic use of coenzyme Q10 and coenzyme Q10-related compounds and formulations. Expert Opin Investig Drugs 19:535-554
93. Yang X, Dai G, Li G et al (2010) Coenzyme Q10 reduces beta-amyloid plaque in an APP/PS1 transgenic mouse model of Alzheimer's disease. J Mol Neurosci 41:110-113
94. Yankovskaya V, Horsefield R, Tornroth S et al (2003) Architecture of succinate dehydrogenase and reactive oxygen species generation. Science 299:700-704
95. Zahid M, Saeed M, Rogan EG et al (2010) Benzene and dopamine catechol quinones could initiate cancer or neurogenic disease. Free Radic Biol Med 48:318-324
96. Zappa F, Ward T, Pedrinis E et al (2003) NAD(P)H: quinone oxidoreductase 1 expression in kidney podocytes. J Histochem Cytochem 51:297-302
97. Zhou Y, Cierpicki T, Jimenez RH et al (2008) NMR solution structure of the integral membrane enzyme DsbB: functional insights into DsbB-catalyzed disulfide bond formation. Mol Cell 31:896-908
98. Zhu Z, Gunner MR (2005) Energetics of quinone-dependent electron and proton transfers in Rhodobacter sphaeroides photosynthetic reaction centers. Biochemistry 44:82-96
99. Zubair A, Frieri M (2013) Role of nuclear factor-K{green}B in breast and colorectal cancer. Curr Allergy Asthma Rep 13:44-49