-
1
-
-
0024237151
-
Sequential oxidation and glutathione addition to 1,4-benzoquinone: Correlation of toxicity with increased glutathione substitution
-
Lau, S. S., Hill, B. A., Highet, R. J., and Monks, T. J. (1988) Sequential oxidation and glutathione addition to 1,4-benzoquinone: correlation of toxicity with increased glutathione substitution. Mol. Pharmacol. 34, 829-836.
-
(1988)
Mol. Pharmacol.
, vol.34
, pp. 829-836
-
-
Lau, S.S.1
Hill, B.A.2
Highet, R.J.3
Monks, T.J.4
-
2
-
-
0022380437
-
Glutathione conjugates of 2-bromohydroquinone are nephrotoxic
-
Monks, T. J., Lau, S. S., Highet, R. J., and Gillette, J. R. (1985) Glutathione conjugates of 2-bromohydroquinone are nephrotoxic. Drug Metab, Dispos. 13, 553-559.
-
(1985)
Drug Metab, Dispos.
, vol.13
, pp. 553-559
-
-
Monks, T.J.1
Lau, S.S.2
Highet, R.J.3
Gillette, J.R.4
-
3
-
-
0023761518
-
2-Bromo(diglutathion-S-yl)hydroquinone nephrotoxicity: Physiological, biochemical, and electrochemical determinants
-
Monks, T. J., Highet, R. J., and Lau, S. S. (1988) 2-Bromo(diglutathion-S-yl)hydroquinone nephrotoxicity: physiological, biochemical, and electrochemical determinants. Mol. Pharmacol. 34, 492-500.
-
(1988)
Mol. Pharmacol.
, vol.34
, pp. 492-500
-
-
Monks, T.J.1
Highet, R.J.2
Lau, S.S.3
-
5
-
-
0002305820
-
Quinone-induced oxidative injury to cells and tissues
-
Sies, H., Ed. Academic Press, London
-
Smith, M. T., Evans, C. G., Thor, H., and Orrenius, S. (1985) Quinone-induced oxidative injury to cells and tissues. In Oxidative Stress (Sies, H., Ed.) pp 91-113, Academic Press, London.
-
(1985)
Oxidative Stress
, pp. 91-113
-
-
Smith, M.T.1
Evans, C.G.2
Thor, H.3
Orrenius, S.4
-
6
-
-
0025213022
-
14C]-hydroquinone and the effect of γ-glutamyl transpeptidase inhibition
-
14C]-hydroquinone and the effect of γ-glutamyl transpeptidase inhibition. Toxicol. Appl. Pharmacol. 103, 121-132.
-
(1990)
Toxicol. Appl. Pharmacol.
, vol.103
, pp. 121-132
-
-
Lau, S.S.1
Monks, T.J.2
-
7
-
-
0021816377
-
Immunological studies on the mechanism of halothane-induced hep a to toxicity: Immunohistochemical evidence of trifluoroacetylated hepatocytes
-
Satoh, H., Fukuda, Y., Anderson, D. K., Ferrans, V. J., Gillette, J. R., and Pohl, L. R. (1985) Immunological studies on the mechanism of halothane-induced hep a to toxicity: immunohistochemical evidence of trifluoroacetylated hepatocytes. J. Pharmacol. Exp. Ther. 233, 857-862.
-
(1985)
J. Pharmacol. Exp. Ther.
, vol.233
, pp. 857-862
-
-
Satoh, H.1
Fukuda, Y.2
Anderson, D.K.3
Ferrans, V.J.4
Gillette, J.R.5
Pohl, L.R.6
-
8
-
-
0027276024
-
Metabolic activation of halothane to neoantigens in C57B1/10 mice: Immunochemical studies
-
Heijink, E., De Matteis, F., Gibbs, A. H., Davies, A., and White, I. N. H. (1993) Metabolic activation of halothane to neoantigens in C57B1/10 mice: immunochemical studies. Eur. J. Pharmacol. 248, 15-25.
-
(1993)
Eur. J. Pharmacol.
, vol.248
, pp. 15-25
-
-
Heijink, E.1
De Matteis, F.2
Gibbs, A.H.3
Davies, A.4
White, I.N.H.5
-
9
-
-
0023243653
-
A sensitive immunochemical assay for acetaminophen-protein adducts
-
Roberts, D. W., Pumford, N. R., Potter, D. W., Benson, R. W., and Hinson, J. A. (1987) A sensitive immunochemical assay for acetaminophen-protein adducts. J. Pharmacol. Exp. Ther. 241, 527-533.
-
(1987)
J. Pharmacol. Exp. Ther.
, vol.241
, pp. 527-533
-
-
Roberts, D.W.1
Pumford, N.R.2
Potter, D.W.3
Benson, R.W.4
Hinson, J.A.5
-
10
-
-
0024202767
-
Immunochemical analysis of acetaminophen covalent binding to proteins
-
Bartolone, J. B., Birge, R. B., Sparks, K., Cohen, S. D., and Khairallah, E. A. (1988) Immunochemical analysis of acetaminophen covalent binding to proteins. Biochem. Pharmacol. 37, 4763-4774.
-
(1988)
Biochem. Pharmacol.
, vol.37
, pp. 4763-4774
-
-
Bartolone, J.B.1
Birge, R.B.2
Sparks, K.3
Cohen, S.D.4
Khairallah, E.A.5
-
11
-
-
0027477180
-
Immunochemical detection of liver protein adducts of the nonsteroidal antiinflammatory drug diclofenac
-
Pumford, N. R., Myers, T. G., Davila, J. C., Highet, R. J., and Pohl, L. R. (1993) Immunochemical detection of liver protein adducts of the nonsteroidal antiinflammatory drug diclofenac. Chem. Res. Toxicol. 6, 147-150.
-
(1993)
Chem. Res. Toxicol.
, vol.6
, pp. 147-150
-
-
Pumford, N.R.1
Myers, T.G.2
Davila, J.C.3
Highet, R.J.4
Pohl, L.R.5
-
12
-
-
0028832745
-
Identification of the mouse liver 44-kDa acetaminophenbinding protein as a subunit of glutamine synthetase
-
Bulera, S. J., Birge, R. B., Cohen, S. D., and Khairallah, E. A. (1995) Identification of the mouse liver 44-kDa acetaminophenbinding protein as a subunit of glutamine synthetase. Toxicol. Appl. Pharmacol. 134, 313-320.
-
(1995)
Toxicol. Appl. Pharmacol.
, vol.134
, pp. 313-320
-
-
Bulera, S.J.1
Birge, R.B.2
Cohen, S.D.3
Khairallah, E.A.4
-
13
-
-
0029914640
-
Acetaminophen-arylated proteins are detected in hepatic subcellular fractions and numerous extra-hepatic tissues in CD-1 and C57B1/ 6J mice
-
Bulera, S. J., Cohen, S. D., and Khariallah, E. A. (1996) Acetaminophen-arylated proteins are detected in hepatic subcellular fractions and numerous extra-hepatic tissues in CD-1 and C57B1/ 6J mice. Toxicology 109, 85-99.
-
(1996)
Toxicology
, vol.109
, pp. 85-99
-
-
Bulera, S.J.1
Cohen, S.D.2
Khariallah, E.A.3
-
14
-
-
0029935673
-
Glutamate dehydrogenase covalently binds to a reactive metabolite of acetaminophen
-
Halmes, N. C., Hinson, J. A., Martin, B. M., and Pumford, N. R. (1996) Glutamate dehydrogenase covalently binds to a reactive metabolite of acetaminophen. Chem. Res. ToxicoL 9, 541-546.
-
(1996)
Chem. Res. ToxicoL
, vol.9
, pp. 541-546
-
-
Halmes, N.C.1
Hinson, J.A.2
Martin, B.M.3
Pumford, N.R.4
-
15
-
-
0028815559
-
Covalent modification of rat liver dipeptidyl peptidase IV (CD26) by the nonsteroidal anti-inflammatory drug diclofenac
-
Hargus, S. J., Martin, B. M., George, J. W., and Pohl, L. R. (1995) Covalent modification of rat liver dipeptidyl peptidase IV (CD26) by the nonsteroidal anti-inflammatory drug diclofenac. Chem Res. Toxicol. 8, 993-996.
-
(1995)
Chem Res. Toxicol.
, vol.8
, pp. 993-996
-
-
Hargus, S.J.1
Martin, B.M.2
George, J.W.3
Pohl, L.R.4
-
16
-
-
0031035604
-
Covalent binding and inhibition of cytochrome P4502E1 by trichloroethylene
-
Halmes, N. C., Samokyszyn, V. M., and Pumford, N. R. (1997) Covalent binding and inhibition of cytochrome P4502E1 by trichloroethylene. Xenobiotica 27, 101-110.
-
(1997)
Xenobiotica
, vol.27
, pp. 101-110
-
-
Halmes, N.C.1
Samokyszyn, V.M.2
Pumford, N.R.3
-
17
-
-
0031461116
-
Detection of benzoquinone adducts to rat liver protein sulfhydryl groups using specifie antibodies
-
Rombach, E. M., and Hanzlik, R. P. (1997) Detection of benzoquinone adducts to rat liver protein sulfhydryl groups using specifie antibodies. Chem. Res. Toxicol. 10, 1407-1411.
-
(1997)
Chem. Res. Toxicol.
, vol.10
, pp. 1407-1411
-
-
Rombach, E.M.1
Hanzlik, R.P.2
-
18
-
-
0028070183
-
Oxidation and acetylation as determinants of 2-bromo(cystein-S-yl)hydroquinone mediated nephrotoxicity
-
Monks, T. J., Lo, H.-H., and Lau, S. S. (1994) Oxidation and acetylation as determinants of 2-bromo(cystein-S-yl)hydroquinone mediated nephrotoxicity. Chem. Res. Toxicol. 7, 495-502.
-
(1994)
Chem. Res. Toxicol.
, vol.7
, pp. 495-502
-
-
Monks, T.J.1
Lo, H.-H.2
Lau, S.S.3
-
19
-
-
0025678706
-
Species differences in renal γ-glutatmyl transpeptidase activity do not correlate with susceptibility to 2-bromo(diglutathion-S-yl)hydroquinone mediated nephrotoxicity
-
Lau, S. S., Jones, T. W., Sioco, R., Hill, B. A., Pinon, R. K., and Monks, T.J. (1990) Species differences in renal γ-glutatmyl transpeptidase activity do not correlate with susceptibility to 2-bromo(diglutathion-S-yl)hydroquinone mediated nephrotoxicity. Toxicology 64, 291-311.
-
(1990)
Toxicology
, vol.64
, pp. 291-311
-
-
Lau, S.S.1
Jones, T.W.2
Sioco, R.3
Hill, B.A.4
Pinon, R.K.5
Monks, T.J.6
-
20
-
-
0025938304
-
The role of γ-glutamyltranspeptidase in hydroquinone-glutathione conjugate mediated nephrotoxicity
-
Hill, B. A., Lo, H.-H., Monks, T. J., and Lau, S. S. (1991) The role of γ-glutamyltranspeptidase in hydroquinone-glutathione conjugate mediated nephrotoxicity. Adv. Exp. Med. Biol. 283, 749-751.
-
(1991)
Adv. Exp. Med. Biol.
, vol.283
, pp. 749-751
-
-
Hill, B.A.1
Lo, H.-H.2
Monks, T.J.3
Lau, S.S.4
-
21
-
-
71849104860
-
Protein measurement with the Folin phenol reagent
-
Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J. (1951) Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193, 265-275.
-
(1951)
J. Biol. Chem.
, vol.193
, pp. 265-275
-
-
Lowry, O.H.1
Rosebrough, N.J.2
Farr, A.L.3
Randall, R.J.4
-
22
-
-
0003448569
-
-
Cold Springs Harbor Laboratory Press, Cold Spring Harbor, New York
-
Harlow, E., and Lane, D. L. (1988) Antibodies. A Laboratory Manual, Cold Springs Harbor Laboratory Press, Cold Spring Harbor, New York.
-
(1988)
Antibodies. A Laboratory Manual
-
-
Harlow, E.1
Lane, D.L.2
-
23
-
-
0018958906
-
A new method for measuring covalent binding of macromolecules to cellular macromolecules
-
Sun, J. D., and Dent, J. G. (1980) A new method for measuring covalent binding of macromolecules to cellular macromolecules. Chem.-Biol. Interact. 32, 41-61.
-
(1980)
Chem.-Biol. Interact.
, vol.32
, pp. 41-61
-
-
Sun, J.D.1
Dent, J.G.2
-
24
-
-
0018795621
-
Isolation of luminal and antiluminal membranes from dog kidney cortex
-
Kinsella, J. L., Holohan, P. D., Pessah, N. I., and Ross, C. R. (1979) Isolation of luminal and antiluminal membranes from dog kidney cortex. Biochim. Biophys. Acta 552, 468-477.
-
(1979)
Biochim. Biophys. Acta
, vol.552
, pp. 468-477
-
-
Kinsella, J.L.1
Holohan, P.D.2
Pessah, N.I.3
Ross, C.R.4
-
26
-
-
0014032729
-
Nuclei from rat liver: Isolation method that combines purity with high yield
-
Blober, G., and Potter, V. R. (1966) Nuclei from rat liver: isolation method that combines purity with high yield. Science 154, 1662-1665.
-
(1966)
Science
, vol.154
, pp. 1662-1665
-
-
Blober, G.1
Potter, V.R.2
-
27
-
-
0013770633
-
A procedure for the isolation of enzymically active rat-liver nuclei
-
Widnell, C. C., and Tata, J. R. (1964) A procedure for the isolation of enzymically active rat-liver nuclei. Biochem. J. 92, 313-317.
-
(1964)
Biochem. J.
, vol.92
, pp. 313-317
-
-
Widnell, C.C.1
Tata, J.R.2
-
28
-
-
0014059118
-
An electron-transport system associated with the outer membrane of liver mitochondria. A biochemical and morphological study
-
Sottocasa, G. L., Kulensterna, B., Ernster, L., and Bergstrand., A. (1967) An electron-transport system associated with the outer membrane of liver mitochondria. A biochemical and morphological study. J. Cell Biol. 32, 425-438.
-
(1967)
J. Cell Biol.
, vol.32
, pp. 425-438
-
-
Sottocasa, G.L.1
Kulensterna, B.2
Ernster, L.3
Bergstrand, A.4
-
29
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli, U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
30
-
-
0009482260
-
Electrophoretic transfer of protein from polyacrylamide gels to nitrocellulose sheets. Procedure and some applications
-
Towbin, H., Staehelin, T., and Gordon, J. (1979) Electrophoretic transfer of protein from polyacrylamide gels to nitrocellulose sheets. Procedure and some applications. Proc. Natl. Acad. Sci. U.S,A. 76, 4350-4354.
-
(1979)
Proc. Natl. Acad. Sci. U.S,A.
, vol.76
, pp. 4350-4354
-
-
Towbin, H.1
Staehelin, T.2
Gordon, J.3
-
31
-
-
0023253196
-
Identification by immunoblotting of three halothane-induced liver microsomal polypeptide antigens recognized by antibodies in sera from patients with halothane-associated hepatitis
-
Kenna, J. G., Neuberger, J., and Williams, R. (1987) Identification by immunoblotting of three halothane-induced liver microsomal polypeptide antigens recognized by antibodies in sera from patients with halothane-associated hepatitis. J. Pharmacol. Exp. Ther. 242, 733-740.
-
(1987)
J. Pharmacol. Exp. Ther.
, vol.242
, pp. 733-740
-
-
Kenna, J.G.1
Neuberger, J.2
Williams, R.3
-
32
-
-
0026022309
-
Tissue acylation by the chlorofluorocarbon substitute 2,2-dichloro1,1,1-trifluoroethane
-
Harris, J. W., Pohl, L. R., Martin, J. L., and Anders, M. W. (1991) Tissue acylation by the chlorofluorocarbon substitute 2,2-dichloro1,1,1-trifluoroethane. Proc. Natl. Acad. Sci. U.S.A 88, 1407-1410.
-
(1991)
Proc. Natl. Acad. Sci. U.S.A
, vol.88
, pp. 1407-1410
-
-
Harris, J.W.1
Pohl, L.R.2
Martin, J.L.3
Anders, M.W.4
-
33
-
-
0026094269
-
Detection of cysteine conjugate metabolite adduct formation with specific mitochondrial proteins using antibodies raised against halothane metabolite adducts
-
Hayden, P. J., Ichimura, T., McCann, D. J., Pohl, L. R., and Stevens, J. L. (1991) Detection of cysteine conjugate metabolite adduct formation with specific mitochondrial proteins using antibodies raised against halothane metabolite adducts. J. Biol. Chem. 266, 18415-18418.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 18415-18418
-
-
Hayden, P.J.1
Ichimura, T.2
McCann, D.J.3
Pohl, L.R.4
Stevens, J.L.5
-
34
-
-
0028882316
-
Evidence for common binding of acetaminophen and bromobenzene to the 58-kDa acetaminophen-binding protein
-
Manautou, J. E., Khairallah, E. A., and Cohen, S. D. (1995) Evidence for common binding of acetaminophen and bromobenzene to the 58-kDa acetaminophen-binding protein. J. Toxicol. Environ. Health 46, 263-269.
-
(1995)
J. Toxicol. Environ. Health
, vol.46
, pp. 263-269
-
-
Manautou, J.E.1
Khairallah, E.A.2
Cohen, S.D.3
-
35
-
-
0026513419
-
Purification, antibody production, and partial amino acid sequence of the 58-kDa acetaminophen-binding liver proteins
-
Bartolone, J. B., Birge, R. B., Bulera, S. J., Bruno, M. K., Nishanian, E. V., Cohen, S. D., and Khairallah, E. A. (1992) Purification, antibody production, and partial amino acid sequence of the 58-kDa acetaminophen-binding liver proteins. Toxicol. Appl. Pharmacol. 113, 19-29.
-
(1992)
Toxicol. Appl. Pharmacol.
, vol.113
, pp. 19-29
-
-
Bartolone, J.B.1
Birge, R.B.2
Bulera, S.J.3
Bruno, M.K.4
Nishanian, E.V.5
Cohen, S.D.6
Khairallah, E.A.7
-
36
-
-
0028950762
-
A comparative study of mouse liver proteins arylated by reactive metabolites of acetamiophen and its nonhepatotoxic regioisomer, S'-hydroxyacetanilide
-
Myers, T. G., Dietz, E. C., Anderson, N. L., Khairallah, E. A., Cohen, S. D., and Nelson, S. D. (1995) A comparative study of mouse liver proteins arylated by reactive metabolites of acetamiophen and its nonhepatotoxic regioisomer, S'-hydroxyacetanilide. Chem. Res. Toxicol. 8, 403-413.
-
(1995)
Chem. Res. Toxicol.
, vol.8
, pp. 403-413
-
-
Myers, T.G.1
Dietz, E.C.2
Anderson, N.L.3
Khairallah, E.A.4
Cohen, S.D.5
Nelson, S.D.6
-
37
-
-
0031013960
-
Comparison of covalent binding of acetaminophen and the regioisomer 3'-hydroxyacetaniIide to mouse liver protein
-
Matthews, A. M., Hinson, J. A., Roberts, D. W., and Pumford, N. R. (1997) Comparison of covalent binding of acetaminophen and the regioisomer 3'-hydroxyacetaniIide to mouse liver protein. Toxicot. Lett. 90, 77-82.
-
(1997)
Toxicot. Lett.
, vol.90
, pp. 77-82
-
-
Matthews, A.M.1
Hinson, J.A.2
Roberts, D.W.3
Pumford, N.R.4
-
38
-
-
0012092005
-
The metabolic activation and carcinogenicity of alkenylbenzenes that occur naturally in many spices
-
Miller, J. A., Miller, E. C., and Phillips, D.H. (1982) The metabolic activation and carcinogenicity of alkenylbenzenes that occur naturally in many spices. Carcinog. Mutagens Environ. 1, 8397.
-
(1982)
Carcinog. Mutagens Environ.
, vol.1
, pp. 8397
-
-
Miller, J.A.1
Miller, E.C.2
Phillips, D.H.3
-
39
-
-
0020692513
-
Structure - Activity studies of the carcinogenicities in the mouse and rat of some naturally occurring synthetic alkenylbenzene derivatives related to safrole and estragole
-
Miller, E. C., Swanson, A. B., Phillips, D. H., Fletcher, T. L., Liem, A., and Miller, J. A. (1983) Structure - activity studies of the carcinogenicities in the mouse and rat of some naturally occurring synthetic alkenylbenzene derivatives related to safrole and estragole. Cancer Res. 43, 1124-1134.
-
(1983)
Cancer Res.
, vol.43
, pp. 1124-1134
-
-
Miller, E.C.1
Swanson, A.B.2
Phillips, D.H.3
Fletcher, T.L.4
Liem, A.5
Miller, J.A.6
-
40
-
-
0029897470
-
Immunochemical detection of covalently modified protein adducts in livers of rats treated with methyleugenol
-
Gardner, I., Bergin, P., Stening, P., Kenna, J. G., and Caldwell, J. (1996) Immunochemical detection of covalently modified protein adducts in livers of rats treated with methyleugenol. Chem. Res. Toxicol. 9, 713-721
-
(1996)
Chem. Res. Toxicol.
, vol.9
, pp. 713-721
-
-
Gardner, I.1
Bergin, P.2
Stening, P.3
Kenna, J.G.4
Caldwell, J.5
|