Differential effects of methyl-4-phenylpyridinium ion, rotenone, and Paraquat on differentiated SH-SY5Y cells

Journal of Toxicology

Volumn 2013, Issue , 2013, Pages

  Martins, João Barbosa ^a   Bastos, Maria De Lourdes ^a   Carvalho, Félix ^a   Capela, João Paulo ^a,b  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSIDADE FERNANDO PESSOA   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; CYCLOHEXIMIDE; DOPAMINE TRANSPORTER; N(G) NITROARGININE METHYL ESTER; PARAQUAT; ROTENONE; TIRON; VANOXERINE;

ARTICLE; CELL DAMAGE; CELL DIFFERENTIATION; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOPAMINERGIC NERVE CELL; DRUG CYTOTOXICITY; HUMAN; HUMAN CELL; HUMAN TISSUE; NERVE CELL NECROSIS; NEUROTOXICITY; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; TIME;

EID: 84876555405     PISSN: 16878191     EISSN: 16878205     Source Type: Journal    
DOI: 10.1155/2013/347312     Document Type: Article

References (54)

1. de Lau L. M., Breteler M. M., Epidemiology of Parkinson's disease. The Lancet Neurology 2006 5 6 525 535 2-s2.0-33745919520 10.1016/S1474-4422(06) 70471-9 (Pubitemid 44262284)
2. Piccini P., Burn D. J., Ceravolo R., Maraganore D., Brooks D. J., The role of inheritance in sporadic Parkinson's disease: evidence from a longitudinal study of dopaminergic function in twins. Annals of Neurology 1999 45 5 577 582 10.1002/1531-8249(199905)45:5<577::AID-ANA5>3.0.CO;2-O (Pubitemid 29217585)
3. Betarbet R., Sherer T. B., MacKenzie G., Garcia-Osuna M., Panov A. V., Greenamyre J. T., Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nature Neuroscience 2000 3 12 1301 1306 2-s2.0-0033681149 10.1038/81834
4. Langston J. W., Ballard P. A. Jr., Parkinson's disease in a chemist working with 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine. The New England Journal of Medicine 1983 309 5, article 310 2-s2.0-0005444118
5. Smeyne R. J., Jackson-Lewis V., The MPTP model of Parkinson's disease. Molecular Brain Research 2005 134 1 57 66 2-s2.0-15744401358 10.1016/j.molbrainres.2004.09.017 (Pubitemid 40409495)
6. Suzuki K., Mizuno Y., Yoshida M., Effects of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP)-like compounds on mitochondrial respiration. Advances in Neurology 1990 53 215 218 2-s2.0-0025117835
7. Greenamyre J. T., Betarbet R., Sherer T. B., The rotenone model of Parkinson's disease: genes, environment and mitochondria. Parkinsonism and Related Disorders 2003 9 supplement 2 S59 S64 2-s2.0-0042160300 10.1016/S1353-8020(03)00023-3 (Pubitemid 36952523)
8. Richardson J. R., Quan Y., Sherer T. B., Greenamyre J. T., Miller G. W., Paraquat neurotoxicity is distinct from that of MPTP and rotenone. Toxicological Sciences 2005 88 1 193 201 2-s2.0-27644459974 10.1093/toxsci/kfi304 (Pubitemid 41548761)
9. Bové J., Prou D., Perier C., Przedborski S., Toxin-induced models of Parkinson's disease. NeuroRx 2005 2 3 484 494 2-s2.0-26844505808 10.1602/neurorx.2.3.484 (Pubitemid 41444882)
10. Gorell J. M., Johnson C. C., Rybicki B. A., Peterson E. L., Richardson R. J., The risk of Parkinson's disease with exposure to pesticides, farming, well water, and rural living. Neurology 1998 50 5 1346 1350 2-s2.0-0031843721 (Pubitemid 28240350)
11. Hughes J. T., Brain damage due to Paraquat poisoning: a fatal case with neuropathological examination of the brain. NeuroToxicology 1988 9 2 243 248 2-s2.0-0023690250
12. Kang M. J., Gil S. J., Koh H. C., Paraquat induces alternation of the dopamine catabolic pathways and glutathione levels in the substantia nigra of mice. Toxicology Letters 2009 188 2 148 152 2-s2.0-67349286448 10.1016/j.toxlet.2009.03.026
13. McCormack A. L., Thiruchelvam M., Manning-Bog A. B., Thiffault C., Langston J. W., Cory-Slechta D. A., Di Monte D. A., Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat. Neurobiology of Disease 2002 10 2 119 127 2-s2.0-0036075892 10.1006/nbdi.2002.0507 (Pubitemid 34775465)
14. Shimizu K., Matsubara K., Ohtaki K., Fujimaru S., Saito O., Shiono H., Paraquat induces long-lasting dopamine overflow through the excitotoxic pathway in the striatum of freely moving rats. Brain Research 2003 976 2 243 252 2-s2.0-0037847451 10.1016/S0006-8993(03)02750-1 (Pubitemid 36570461)
15. Tawara T., Fukushima T., Hojo N., Isobe A., Shiwaku K., Setogawa T., Yamane Y., Effects of paraquat on mitochondrial electron transport system and catecholamine contents in rat brain. Archives of Toxicology 1996 70 9 585 589 2-s2.0-0030004770 10.1007/s002040050316 (Pubitemid 26226682)
16. Bagchi D., Bagchi M., Hassoun E. A., Stohs S. J., In vitro and in vivo generation of reactive oxygen species, DNA damage and lactate dehydrogenase leakage by selected pesticides. Toxicology 1995 104 1-3 129 140 2-s2.0-0029610549 10.1016/0300-483X(95)03156-A (Pubitemid 26016384)
17. Presgraves S. P., Ahmed T., Borwege S., Joyce J. N., Terminally differentiated SH-SY5Y cells provide a model system for studying neuroprotective effects of dopamine agonists. Neurotoxicity Research 2003 5 8 579 598 2-s2.0-2442426175 10.1007/BF03033178
18. Ferreira P. S., Nogueira T. B., Costa V. M., Branco P. S., Ferreira L. M., Fernandes E., Bastos M. L., Meisel A., Carvalho F., Capela J. P., Neurotoxicity of "ecstasy" and its metabolites in human dopaminergic differentiated SH-SY5Y cells. Toxicology Letters 2013 216 2-3 159 170 10.1016/j.toxlet.2012.11.015
19. Molina-Jimenez M. F., Sanchez-Reus M. I., Benedi J., Effect of fraxetin and myricetin on rotenone-induced cytotoxicity in SH-SY5Y cells: comparison with N -acetylcysteine. European Journal of Pharmacology 2003 472 1-2 81 87 2-s2.0-0037629379 10.1016/S0014-2999(03)01902-2 (Pubitemid 36830994)
20. Pan T., Rawal P., Wu Y., Xie W., Jankovic J., Le W., Rapamycin protects against rotenone-induced apoptosis through autophagy induction. Neuroscience 2009 164 2 541 551 2-s2.0-70349750492 10.1016/j.neuroscience.2009.08.014
21. Chau K. Y., Korlipara L. V. P., Cooper J. M., Schapira A. H. V., Protection against paraquat and A53T alpha-synuclein toxicity by cabergoline is partially mediated by dopamine receptors. Journal of the Neurological Sciences 2009 278 1-2 44 53 2-s2.0-58749109595 10.1016/j.jns.2008.11.012
22. +-induced neurotoxicity in SH-SY5Y cells. Brain Research 2004 1003 1-2 86 97 2-s2.0-12144290127 10.1016/j.brainres.2003.11.073 (Pubitemid 38317088)
23. Yang W., Tiffany-Castiglioni E., The bipyridyl herbicide paraquat produces oxidative stress-mediated toxicity in human neuroblastoma SH-SY5Y cells: relevance to the dopaminergic pathogenesis. Journal of Toxicology and Environmental Health-Part A 2005 68 22 1939 1961 2-s2.0-28844448703 10.1080/15287390500226987 (Pubitemid 41765788)
24. +-induced cytotoxicity in human dopaminergic SH-SY5Y cells. Journal of Ethnopharmacology 2010 130 2 290 298 2-s2.0-77954955677 10.1016/j.jep.2010.05.006
25. Capela J. P., Macedo C., Branco P. S., Ferreira L. M., Lobo A. M., Fernandes E., Remião F., Bastos M. L., Dirnagl U., Meisel A., Carvalho F., Neurotoxicity mechanisms of thioether ecstasy metabolites. Neuroscience 2007 146 4 1743 1757 2-s2.0-34249010184 10.1016/j.neuroscience.2007.03.028 (Pubitemid 46795533)
26. Yamada J., Yoshimura S., Yamakawa H., Sawada M., Nakagawa M., Hara S., Kaku Y., Iwama T., Naganawa T., Banno Y., Nakashima S., Sakai N., Cell permeable ROS scavengers, Tiron and Tempol, rescue PC12 cell death caused by pyrogallol or hypoxia/reoxygenation. Neuroscience Research 2003 45 1 1 8 2-s2.0-0037221509 10.1016/S0168-0102(02)00196-7 (Pubitemid 36044463)
27. Lopes M. A., Meisel A., Dirnagl U., Carvalho F. D., Bastos M. D. L., Doxorubicin induces biphasic neurotoxicity to rat cortical neurons. NeuroToxicology 2008 29 2 286 293 2-s2.0-39749200035 10.1016/j.neuro.2007.12.003
28. Bau J. T., Kurz E. U., Sodium salicylate is a novel catalytic inhibitor of human DNA topoisomerase II alpha. Biochemical Pharmacology 2011 81 3 345 354 2-s2.0-78650684679 10.1016/j.bcp.2010.10.009
29. Capela J. P., Ruscher K., Lautenschlager M., Freyer D., Dirnagl U., Gaio A. R., Bastos M. L., Meisel A., Carvalho F., Ecstasy-induced cell death in cortical neuronal cultures is serotonin 2A-receptor-dependent and potentiated under hyperthermia. Neuroscience 2006 139 3 1069 1081 2-s2.0-33646162180 10.1016/j.neuroscience.2006.01.007
30. Nakamura K., Tsuchiya D., Inden M., Taniguchi T., In vitro neurodegeneration model: dopaminergic toxin-induced apoptosis in human SH-SY5Y cells. International Congress Series 2004 1260 287 290
31. De Andrade D. V. G., Madureira de Oliveria D., Barreto G., Bertolino L. A., Saraceno E., Capani F., Giraldez L. D., Effects of the extract of Anemopaegma mirandum (Catuaba) on Rotenone-induced apoptosis in human neuroblastomas SH-SY5Y cells. Brain Research 2008 1198 188 196 2-s2.0-43049095135 10.1016/j.brainres.2008.01.006
32. Lambert A. J., Brand M. D., Inhibitors of the quinone-binding site allow rapid superoxide production from mitochondrial NADH:ubiquinone oxidoreductase (complex I). The Journal of Biological Chemistry 2004 279 38 39414 39420 2-s2.0-4544354262 10.1074/jbc.M406576200 (Pubitemid 39258206)
33. Hartley A., Stone J. M., Heron C., Cooper J. M., Schapira A. H. V., Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: relevance to Parkinson's disease. Journal of Neurochemistry 1994 63 5 1987 1990 2-s2.0-0028127129 (Pubitemid 24326248)
34. +)-induced toxicity in differentiated human SH-SY5Y neuroblastoma cells. Neuroscience Letters 2006 405 1-2 46 51 2-s2.0-33746472503 10.1016/j.neulet.2006.06.061 (Pubitemid 44142827)
35. +-induced apoptosis in human SH-SY5Y neuroblastoma cells. Journal of Neuroscience Research 1999 55 5 620 628 (Pubitemid 29117620)
36. Cheung Y. T., Lau W. K. W., Yu M. S., Lai C. S. W., Yeung S. C., So K. F., Chang R. C. C., Effects of all- trans -retinoic acid on human SH-SY5Y neuroblastoma as in vitro model in neurotoxicity research. NeuroToxicology 2009 30 1 127 135 2-s2.0-58749087320 10.1016/j.neuro.2008.11.001
37. Dinis-Oliveira R. J., Sousa C., Remião F., Duarte J. A., Ferreira R., Sánchez Navarro A., Bastos M. L., Carvalho F., Sodium salicylate prevents paraquat-induced apoptosis in the rat lung. Free Radical Biology and Medicine 2007 43 1 48 61 2-s2.0-34249903639 10.1016/j.freeradbiomed.2007.03.014 (Pubitemid 46874835)
38. Mattson M. P., Neuronal life-and-death signaling, apoptosis, and neurodegenerative disorders. Antioxidants and Redox Signaling 2006 8 11-12 1997 2006 2-s2.0-33947623671 (Pubitemid 46489627)
39. Jenner P., Oxidative stress as a cause of Parkinson's disease. Acta Neurologica Scandinavica, Supplement 1991 84 136 6 15 2-s2.0-0026337175
40. Dinis-Oliveira R. J., de Pinho P. G., Ferreira A. C. S., Silva A. M. S., Afonso C., Bastos M. D. L., Remião F., Duarte J. A., Carvalho F., Reactivity of paraquat with sodium salicylate: formation of stable complexes. Toxicology 2008 249 2-3 130 139 2-s2.0-46449127649 10.1016/j.tox.2008.04.014
41. Franco R., Li S., Rodriguez-Rocha H., Burns M., Panayiotidis M. I., Molecular mechanisms of pesticide-induced neurotoxicity: relevance to Parkinson's disease. Chemico-Biological Interactions 2010 188 2 289 300 2-s2.0-77956650279 10.1016/j.cbi.2010.06.003
42. La Voie M. J., Hastings T. G., Peroxynitrite- and nitrite-induced oxidation of dopamine: implications for nitric oxide in dopaminergic cell loss. Journal of Neurochemistry 1999 73 6 2546 2554 2-s2.0-0007845042 10.1046/j.1471-4159.1999.0732546.x
43. Yang W. L., Sun A. Y., Paraquat-induced free radical reaction in mouse brain microsomes. Neurochemical Research 1998 23 1 47 53 2-s2.0-0031943867 10.1023/A:1022497319548 (Pubitemid 28145690)
44. Harms C., Lautenschlager M., Bergk A., Katchanov J., Freyer D., Kapinya K., Herwig U., Megow D., Dirnagl U., Weber J. R., Hörtnagl H., Differential mechanisms of neuroprotection by 17 β -estradiol in apoptotic versus necrotic neurodegeneration. Journal of Neuroscience 2001 21 8 2600 2609 2-s2.0-0035871646 (Pubitemid 32298202)
45. Barlow B. K., Thiruchelvam M. J., Bennice L., Cory-Slechta D. A., Ballatori N., Richfield E. K., Increased synaptosomal dopamine content and brain concentration of paraquat produced by selective dithiocarbamates. Journal of Neurochemistry 2003 85 4 1075 1086 2-s2.0-0038248977 (Pubitemid 36578639)
46. + and rotenone toxicity: oxidation of thioredoxin and caspase-3 activation. Toxicological Sciences 2007 95 1 163 171 2-s2.0-33845645902 10.1093/toxsci/kfl125 (Pubitemid 44970055)
47. + increases the vulnerability to oxidative stress rather than directly mediating oxidative damage in human neuroblastoma cells. Experimental Neurology 2000 165 1 164 171 2-s2.0-0033830359 10.1006/exnr.2000.7460
48. + actions. Journal of Neuroscience Research 2003 72 1 89 97 2-s2.0-0037381099 10.1002/jnr.10540 (Pubitemid 36373814)
49. +-induced cell death in a dopaminergic neuronal cell line: role of macromolecule synthesis, cytosolic calcium, caspase, and Bcl-2-related proteins. Experimental Neurology 1999 159 1 274 282 2-s2.0-0032854449 10.1006/exnr.1999.7133 (Pubitemid 29444924)
50. Sairam K., Saravanan K. S., Banerjee R., Mohanakumar K. P., Non-steroidal anti-inflammatory drug sodium salicylate, but not diclofenac or celecoxib, protects against 1-methyl-4-phenyl pyridinium-induced dopaminergic neurotoxicity in rats. Brain Research 2003 966 2 245 252 2-s2.0-0037459783 10.1016/S0006-8993(02)04174-4 (Pubitemid 36255587)
51. Pei W., Liou A. K., Chen J., Two caspase-mediated apoptotic pathways induced by rotenone toxicity in cortical neuronal cells. The FASEB Journal 2003 17 3 520 522 2-s2.0-0037364455
52. Sai Y., Wu Q., Le W., Ye F., Li Y., Dong Z., Rotenone-induced PC12 cell toxicity is caused by oxidative stress resulting from altered dopamine metabolism. Toxicology in Vitro 2008 22 6 1461 1468 2-s2.0-49149102041 10.1016/j.tiv.2008.04.019
53. Thakur P., Nehru B., Anti-inflammatory properties rather than anti-oxidant capability is the major mechanism of neuroprotection by sodium salicylate in a chronic rotenone model of Parkinson's disease. Neuroscience 2013 231 420 431 10.1016/j.neuroscience.2012.11.006
54. Lee J., Huang M. S., Yang I. C., Lai T. C., Wang J. L., Pang V. F., Hsiao M., Kuo M. Y. P., Essential roles of caspases and their upstream regulators in rotenone-induced apoptosis. Biochemical and Biophysical Research Communications 2008 371 1 33 38 2-s2.0-46349111715 10.1016/j.bbrc.2008.03.149