The role of inheritance in sporadic Parkinson's disease: Evidence from a longitudinal study of dopaminergic function in twins

Annals of Neurology

Volumn 45, Issue 5, 1999, Pages 577-582

  Piccini, Paola ^a   Burn, David J ^a   Ceravolo, Roberto ^a   Maraganore, Demetrius ^b   Brooks, David J ^a,c  

^a MRC Cyclotron Unit   (United Kingdom)

^b MAYO CLINIC ROCHESTER   (United States)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DOPA;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; DIZYGOTIC TWINS; DOPAMINERGIC SYSTEM; FAMILIAL DISEASE; FEMALE; FOLLOW UP; GENETIC DISORDER; HUMAN; INHERITANCE; LONGITUDINAL STUDY; MALE; MONOZYGOTIC TWINS; OUTCOMES RESEARCH; PARKINSON DISEASE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL;

EID: 0032913951     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/1531-8249(199905)45:5<577::AID-ANA5>3.0.CO;2-O     Document Type: Article

References (28)

1. Bower JH, Maraganore DM, McDonnell SK, Rocca WA. Incidence of Parkinson's disease in Olmested County, Minnesota. Neurology 1998;50:A98 (Abstract)
2. Bennett DA, Beckett LA, Murray AM, et al. Prevalence of Parkinsonian signs and associate mortality in a community population of older people. N Engl J Med 1996;334:71-76
3. De Rijk MC, Tzourio C, Breteler MMB, et al. Prevalence of parkinsonism and Parkinson's disease in Europe: the EUROPARKINSON collaborative study. J Neurol Neurosurg Psychiatry 1997;62:10-15
4. Polymeropoulos MH, Higgins JJ, Golbe LI, et al. Mapping of a gene for Parkinson's disease to chromosome 4q21-q23. Science 1996;274:1197-1199
5. Polymeropoulos MH, Lavedan C, Leroy E, et al. Mutation of the α-synuclein gene identified in families with Parkinson's disease. Science 1997;276:2045-2047
6. Kruger R, Kuhn W, Muller T, et al. Ala30Pro mutation in the gene encoding α-synuclein in Parkinson's disease. Nat Genet 1998;18:106-108
7. Kitada T, Asakawa S, Hattori N, et al. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 1998;392:605-608
8. Scott WK, Stajich JM, Yamaoka LH, et al. Genetic complexity in Parkinson's disease. Science 1997;277:387 (Letter)
9. Vaughan J, Durr A, Tassin J, et al. The α-synuclein ALA53Thr mutation is not a common cause of familial Parkinson's disease: a study of 230 European cases. Ann Neurol 1998;44:270-273
10. Farrer M, Wavrant-De Vrieze F, Crook R, et al. Low frequency of α-synuclein mutations in familial Parkinson's disease. Ann Neurol 1998;43:394-397
11. Chan P, Tanner CM, Jiang X, Langston JW. Failure to find the alpha-synuclein gene missense mutation (G209A) in 100 patients with younger onset Parkinson's disease. Neurology 1998; 50:513-514
12. Golbe LI. The genetics of Parkinson's disease: a reconsideration. Neurology 1990;40(Suppl 3):7-14
13. Zimmerman TR, Bhati M, Calne DB, Duvoisin RC. Parkinson's disease in monozygotic twins: a follow up. Neurology 1991;41(Suppl 1):225 (Abstract)
14. Weeks RA, Piccini P, Harding AE, Brooks DJ. PET demonstrates a parallel loss of D1 and D2 dopamine receptors in asymptomatic carriers of Huntington's disease. Ann Neurol 1996;40:49-54
15. 18F]dopa positron emission tomography study. Ann Neurol 1997;41: 222-228
16. 18F-dopa and positron emission tomography. Neurology 1992;42:1894-1900
17. 18F]dopa uptake in Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy. Ann Neurol 1990;28: 547-555
18. Talairach J, Tournoux P. Coplanar stereotaxic atlas of the human brain. New York: Georg Thieme, 1988
19. Patlak CS, Blasberg RG, Fentsetmacher JD. Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. J Cereb Blood Flow Metab 1983;3:1-7
20. Sawle GV, Playford ED, Burn DJ, et al. Separating Parkinson's disease from normality. Discriminant function analysis of fluorodopa F18 positron emission tomography data. Arch Neurol 1994;31:237-243
21. Breitner JCS, Murphy EA. Twin studies of Alzheimer's disease: some prediction using a genetic model. Am J Med Genet 1992; 44:628-634
22. Breitner JCS, Gatz M, Bergem ALM, et al. Use of twin cohorts for research in Alzheimer's disease. Neurology 1993;43:261-267
23. Phillips DIW. Twin studies in medical research: can they tell us whether diseases are genetically determined? Lancet 1993;1: 1008-1009
24. Vieregge P, Schiffke KA, Friedrich HJ, et al. Parkinson's disease in twins. Neurology 1992;42:1453-1461
25. Martyn CN, Osmond C. Parkinson's disease and the environment in early life. J Neurol Sci 1995;132:201-206
26. Ward CD, Duvoisin RC, Ince SE, et al. Parkinson's disease in 65 pairs of twins and in a set of quadruplets. Neurology 1983; 33:815-824
27. Marttila RJ, Kaprio J, Koskenvuo MD, Rinne UK. Parkinson's disease in a nationwide twin cohort. Neurology 1988;38:1217-1219
28. Johnson WG, Hodge SE, Duvoisin RC. Twin studies and the genetics of Parkinson's disease. Mov Disord 1990;3:187-194