Protective effects of Gastrodia elata Blume on MPP+-induced cytotoxicity in human dopaminergic SH-SY5Y cells

Journal of Ethnopharmacology

Volumn 130, Issue 2, 2010, Pages 290-298

  An, Hua ^a   Kim, In Su ^a   Koppula, Sushruta ^a   Kim, Byung Wook ^a   Park, Pyo Jam ^a   Lim, Beong Ou ^a   Choi, Wahn Soo ^b   Lee, Kwang Ho ^a   Choi, Dong Kug ^a  

^a Konkuk University   (South Korea)

^b Konkuk University School of Medicine   (South Korea)

Author keywords

Gastrodia elata (GE); Mitochondrial dysfunction; MPP+; Parkinson's disease; ROS

Indexed keywords

1,1 DIMETHYL 4 PHENYLPIPERAZINIUM; CASPASE 3; GASTRODIA ELATA EXTRACT; NEUROPROTECTIVE AGENT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; 1 METHYL 4 PHENYLPYRIDINIUM; BAX PROTEIN, HUMAN; CASP3 PROTEIN, HUMAN; DOPAMINE; FREE RADICAL; PLANT EXTRACT;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DOPAMINERGIC NERVE CELL; DOSE RESPONSE; ELECTRON SPIN RESONANCE; FLOW CYTOMETRY; GASTRODIA ELATA; HUMAN; HUMAN CELL; NEUROPROTECTION; OXIDATIVE STRESS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; ANIMAL; CELL PROTECTION; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; GASTRODIA; METABOLISM; MOUSE; NERVE CELL; PATHOLOGY; PLANT ROOT; TOXICITY; TUMOR CELL LINE;

1-METHYL-4-PHENYLPYRIDINIUM; ANIMALS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CELL LINE, TUMOR; CELL SURVIVAL; CYTOPROTECTION; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FREE RADICALS; GASTRODIA; HUMANS; MICE; NEURONS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PLANT EXTRACTS; PLANT ROOTS; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-BCL-2;

GASTRODIA ELATA; ORCHIDACEAE;

EID: 77954955677     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2010.05.006     Document Type: Article

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