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Volumn 8, Issue 4, 2013, Pages

Genetic Variants and Increased Expression of Parascaris equorum P-glycoprotein-11 in Populations with Decreased Ivermectin Susceptibility

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; IVERMECTIN; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 11; MULTIDRUG RESISTANCE PROTEIN 16; UNCLASSIFIED DRUG;

EID: 84876534911     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0061635     Document Type: Article
Times cited : (66)

References (57)
  • 1
    • 84860539108 scopus 로고    scopus 로고
    • History of avermectin and ivermectin, with notes on the history of other macrocyclic lactone antiparasitic agents
    • Campbell WC, (2011) History of avermectin and ivermectin, with notes on the history of other macrocyclic lactone antiparasitic agents. Curr Pharm Biotechnol 13: 853-865.
    • (2011) Curr Pharm Biotechnol , vol.13 , pp. 853-865
    • Campbell, W.C.1
  • 2
    • 0004371005 scopus 로고    scopus 로고
    • Pharmacology of anthelmintic resistance
    • Sangster NC, Gill J, (1999) Pharmacology of anthelmintic resistance. Parasitol Today 15: 141-146.
    • (1999) Parasitol Today , vol.15 , pp. 141-146
    • Sangster, N.C.1    Gill, J.2
  • 6
    • 0041331790 scopus 로고    scopus 로고
    • P-glycoprotein in helminths: function and perspectives for anthelmintic treatment and reversal of resistance
    • Kerboeuf D, Blackhall W, Kaminsky R, von Samson-Himmelstjerna G, (2003) P-glycoprotein in helminths: function and perspectives for anthelmintic treatment and reversal of resistance. Int J Antimicrob Agents 22: 332-346.
    • (2003) Int J Antimicrob Agents , vol.22 , pp. 332-346
    • Kerboeuf, D.1    Blackhall, W.2    Kaminsky, R.3    von Samson-Himmelstjerna, G.4
  • 7
    • 0028988540 scopus 로고
    • A P-glycoprotein protects Caenorhabditis elegans against natural toxins
    • Broeks A, Janssen HW, Calafat J, Plasterk RH, (1995) A P-glycoprotein protects Caenorhabditis elegans against natural toxins. EMBO J 14: 1858-1866.
    • (1995) EMBO J , vol.14 , pp. 1858-1866
    • Broeks, A.1    Janssen, H.W.2    Calafat, J.3    Plasterk, R.H.4
  • 8
    • 0032531334 scopus 로고    scopus 로고
    • Selection at a P-glycoprotein gene in ivermectin- and moxidectin-selected strains of Haemonchus contortus
    • Blackhall WJ, Liu HY, Xu M, Prichard RK, Beech RN, (1998) Selection at a P-glycoprotein gene in ivermectin- and moxidectin-selected strains of Haemonchus contortus. Mol Biochem Parasitol 95: 193-201.
    • (1998) Mol Biochem Parasitol , vol.95 , pp. 193-201
    • Blackhall, W.J.1    Liu, H.Y.2    Xu, M.3    Prichard, R.K.4    Beech, R.N.5
  • 9
    • 38749105426 scopus 로고    scopus 로고
    • P-glycoprotein selection in strains of Haemonchus contortus resistant to benzimidazoles
    • Blackhall WJ, Prichard RK, Beech RN, (2008) P-glycoprotein selection in strains of Haemonchus contortus resistant to benzimidazoles. Vet Parasitol 152: 101-107.
    • (2008) Vet Parasitol , vol.152 , pp. 101-107
    • Blackhall, W.J.1    Prichard, R.K.2    Beech, R.N.3
  • 10
    • 0032520963 scopus 로고    scopus 로고
    • Ivermectin resistance in nematodes may be caused by alteration of P-glycoprotein homolog
    • Xu M, Molento M, Blackhall W, Ribeiro P, Beech R, et al. (1998) Ivermectin resistance in nematodes may be caused by alteration of P-glycoprotein homolog. Mol Biochem Parasitol 91: 327-335.
    • (1998) Mol Biochem Parasitol , vol.91 , pp. 327-335
    • Xu, M.1    Molento, M.2    Blackhall, W.3    Ribeiro, P.4    Beech, R.5
  • 11
    • 0026618689 scopus 로고
    • The P-glycoprotein gene family of Caenorhabditis elegans. Cloning and characterization of genomic and complementary DNA sequences
    • Lincke CR, The I, van Groenigen M, Borst P, (1992) The P-glycoprotein gene family of Caenorhabditis elegans. Cloning and characterization of genomic and complementary DNA sequences. J Mol Biol 228: 701-711.
    • (1992) J Mol Biol , vol.228 , pp. 701-711
    • Lincke, C.R.1    The, I.2    van Groenigen, M.3    Borst, P.4
  • 12
    • 34347399591 scopus 로고    scopus 로고
    • ABC transporters and beta-tubulin in macrocyclic lactone resistance: prospects for marker development
    • Prichard RK, Roulet A, (2007) ABC transporters and beta-tubulin in macrocyclic lactone resistance: prospects for marker development. Parasitology 134: 1123-1132.
    • (2007) Parasitology , vol.134 , pp. 1123-1132
    • Prichard, R.K.1    Roulet, A.2
  • 13
    • 0029910521 scopus 로고    scopus 로고
    • Homologues of the human multidrug resistance genes MRP and MDR contribute to heavy metal resistance in the soil nematode Caenorhabditis elegans
    • Broeks A, Gerrard B, Allikmets R, Dean M, Plasterk RH, (1996) Homologues of the human multidrug resistance genes MRP and MDR contribute to heavy metal resistance in the soil nematode Caenorhabditis elegans. EMBO J 15: 6132-6143.
    • (1996) EMBO J , vol.15 , pp. 6132-6143
    • Broeks, A.1    Gerrard, B.2    Allikmets, R.3    Dean, M.4    Plasterk, R.H.5
  • 14
    • 84868212803 scopus 로고    scopus 로고
    • The role of several ABC transporter genes in ivermectin resistance in Caenorhabditis elegans
    • Yan R, Urdaneta-Marquez L, Keller K, James CE, Davey MW, et al. (2012) The role of several ABC transporter genes in ivermectin resistance in Caenorhabditis elegans. Vet Parasitol 190: 519-529.
    • (2012) Vet Parasitol , vol.190 , pp. 519-529
    • Yan, R.1    Urdaneta-Marquez, L.2    Keller, K.3    James, C.E.4    Davey, M.W.5
  • 15
    • 77957363104 scopus 로고    scopus 로고
    • Inventory and analysis of ATP-binding cassette (ABC) systems in Brugia malayi
    • Ardelli BF, Stitt LE, Tompkins JB, (2010) Inventory and analysis of ATP-binding cassette (ABC) systems in Brugia malayi. Parasitology 137: 1195-1212.
    • (2010) Parasitology , vol.137 , pp. 1195-1212
    • Ardelli, B.F.1    Stitt, L.E.2    Tompkins, J.B.3
  • 16
    • 84859059132 scopus 로고    scopus 로고
    • P-glycoproteins of Haemonchus contortus: development of real-time PCR assays for gene expression studies
    • Williamson SM, Wolstenholme AJ, (2011) P-glycoproteins of Haemonchus contortus: development of real-time PCR assays for gene expression studies. J Helminthol 86: 1-7.
    • (2011) J Helminthol , vol.86 , pp. 1-7
    • Williamson, S.M.1    Wolstenholme, A.J.2
  • 17
    • 0031865592 scopus 로고    scopus 로고
    • Use of P-glycoprotein gene probes to investigate anthelmintic resistance in Haemonchus contortus and comparison with Onchocerca volvulus
    • Kwa MS, Okoli MN, Schulz-Key H, Okongkwo PO, Roos MH, (1998) Use of P-glycoprotein gene probes to investigate anthelmintic resistance in Haemonchus contortus and comparison with Onchocerca volvulus. Int J Parasitol 28: 1235-1240.
    • (1998) Int J Parasitol , vol.28 , pp. 1235-1240
    • Kwa, M.S.1    Okoli, M.N.2    Schulz-Key, H.3    Okongkwo, P.O.4    Roos, M.H.5
  • 18
    • 0032789210 scopus 로고    scopus 로고
    • Haemonchus contortus: sequence heterogeneity of internucleotide binding domains from P-glycoproteins
    • Sangster NC, Bannan SC, Weiss AS, Nulf SC, Klein RD, et al. (1999) Haemonchus contortus: sequence heterogeneity of internucleotide binding domains from P-glycoproteins. Exp Parasitol 91: 250-257.
    • (1999) Exp Parasitol , vol.91 , pp. 250-257
    • Sangster, N.C.1    Bannan, S.C.2    Weiss, A.S.3    Nulf, S.C.4    Klein, R.D.5
  • 20
    • 79960556216 scopus 로고    scopus 로고
    • Gene expression changes in a P-glycoprotein (Tci-pgp-9) putatively associated with ivermectin resistance in Teladorsagia circumcincta
    • Dicker AJ, Nisbet AJ, Skuce PJ, (2011) Gene expression changes in a P-glycoprotein (Tci-pgp-9) putatively associated with ivermectin resistance in Teladorsagia circumcincta. Int J Parasitol 41: 935-942.
    • (2011) Int J Parasitol , vol.41 , pp. 935-942
    • Dicker, A.J.1    Nisbet, A.J.2    Skuce, P.J.3
  • 21
    • 0032790754 scopus 로고    scopus 로고
    • Identification and stage-specific expression of two putative P-glycoprotein coding genes in Onchocerca volvulus
    • Huang YJ, Prichard RK, (1999) Identification and stage-specific expression of two putative P-glycoprotein coding genes in Onchocerca volvulus. Mol Biochem Parasitol 102: 273-281.
    • (1999) Mol Biochem Parasitol , vol.102 , pp. 273-281
    • Huang, Y.J.1    Prichard, R.K.2
  • 22
    • 70349841137 scopus 로고    scopus 로고
    • Diagnosis and control of anthelmintic-resistant Parascaris equorum
    • Reinemeyer CR, (2009) Diagnosis and control of anthelmintic-resistant Parascaris equorum. Parasit Vectors 2Suppl 2: S8.
    • (2009) Parasit Vectors , vol.2
    • Reinemeyer, C.R.1
  • 23
    • 84856796275 scopus 로고    scopus 로고
    • Anthelmintic resistance in non-strongylid parasites of horses
    • Reinemeyer CR, (2011) Anthelmintic resistance in non-strongylid parasites of horses. Vet Parasitol 185: 9-15.
    • (2011) Vet Parasitol , vol.185 , pp. 9-15
    • Reinemeyer, C.R.1
  • 24
    • 70349823669 scopus 로고    scopus 로고
    • Effects of worm control practices examined by a combined faecal egg count and questionnaire survey on horse farms in Germany, Italy and the UK
    • von Samson-Himmelstjerna G, Traversa D, Demeler J, Rohn K, Milillo P, et al. (2009) Effects of worm control practices examined by a combined faecal egg count and questionnaire survey on horse farms in Germany, Italy and the UK. Parasit Vectors 2Suppl 2: S3.
    • (2009) Parasit Vectors , vol.2
    • von Samson-Himmelstjerna, G.1    Traversa, D.2    Demeler, J.3    Rohn, K.4    Milillo, P.5
  • 25
    • 0034017639 scopus 로고    scopus 로고
    • L-glutamate binding sites of parasitic nematodes: an association with ivermectin resistance?
    • Hejmadi MV, Jagannathan S, Delany NS, Coles GC, Wolstenholme AJ, (2000) L-glutamate binding sites of parasitic nematodes: an association with ivermectin resistance? Parasitology 120 (Pt 5): 535-545.
    • (2000) Parasitology , vol.120 , Issue.Pt 5 , pp. 535-545
    • Hejmadi, M.V.1    Jagannathan, S.2    Delany, N.S.3    Coles, G.C.4    Wolstenholme, A.J.5
  • 27
    • 2642551393 scopus 로고    scopus 로고
    • Mutations in the extracellular domains of glutamate-gated chloride channel alpha3 and beta subunits from ivermectin-resistant Cooperia oncophora affect agonist sensitivity
    • Njue AI, Hayashi J, Kinne L, Feng XP, Prichard RK, (2004) Mutations in the extracellular domains of glutamate-gated chloride channel alpha3 and beta subunits from ivermectin-resistant Cooperia oncophora affect agonist sensitivity. J Neurochem 89: 1137-1147.
    • (2004) J Neurochem , vol.89 , pp. 1137-1147
    • Njue, A.I.1    Hayashi, J.2    Kinne, L.3    Feng, X.P.4    Prichard, R.K.5
  • 28
    • 80054694509 scopus 로고    scopus 로고
    • Candidate anthelmintic resistance-associated gene expression and sequence polymorphisms in a triple-resistant field isolate of Haemonchus contortus
    • Williamson SM, Storey B, Howell S, Harper KM, Kaplan RM, et al. (2011) Candidate anthelmintic resistance-associated gene expression and sequence polymorphisms in a triple-resistant field isolate of Haemonchus contortus. Mol Biochem Parasitol 180: 99-105.
    • (2011) Mol Biochem Parasitol , vol.180 , pp. 99-105
    • Williamson, S.M.1    Storey, B.2    Howell, S.3    Harper, K.M.4    Kaplan, R.M.5
  • 29
    • 57649087686 scopus 로고    scopus 로고
    • Increased expression of ABC transport proteins is associated with ivermectin resistance in the model nematode Caenorhabditis elegans
    • James CE, Davey MW, (2009) Increased expression of ABC transport proteins is associated with ivermectin resistance in the model nematode Caenorhabditis elegans. Int J Parasitol 39: 213-220.
    • (2009) Int J Parasitol , vol.39 , pp. 213-220
    • James, C.E.1    Davey, M.W.2
  • 31
    • 84860461870 scopus 로고    scopus 로고
    • P-glycoproteins and other multidrug resistance transporters in the pharmacology of anthelmintics: Prospects for reversing transport-dependent anthelmintic resistance
    • Lespine A, Ménez C, Bourguinat C, Prichard RK, (2012) P-glycoproteins and other multidrug resistance transporters in the pharmacology of anthelmintics: Prospects for reversing transport-dependent anthelmintic resistance. Int J Parasitol: Drug Drug Resist 2: 58-75.
    • (2012) Int J Parasitol: Drug Drug Resist , vol.2 , pp. 58-75
    • Lespine, A.1    Ménez, C.2    Bourguinat, C.3    Prichard, R.K.4
  • 32
    • 0018509838 scopus 로고
    • The migration and development of Parascaris equorum in the horse
    • Clayton HM, Duncan JL, (1979) The migration and development of Parascaris equorum in the horse. Int J Parasitol 9: 285-292.
    • (1979) Int J Parasitol , vol.9 , pp. 285-292
    • Clayton, H.M.1    Duncan, J.L.2
  • 33
    • 79954529507 scopus 로고    scopus 로고
    • ProtTest 3: fast selection of best-fit models of protein evolution
    • Darriba D, Taboada GL, Doallo R, Posada D, (2011) ProtTest 3: fast selection of best-fit models of protein evolution. Bioinformatics 27: 1164-1165.
    • (2011) Bioinformatics , vol.27 , pp. 1164-1165
    • Darriba, D.1    Taboada, G.L.2    Doallo, R.3    Posada, D.4
  • 34
    • 18744382506 scopus 로고    scopus 로고
    • ProtTest: selection of best-fit models of protein evolution
    • Abascal F, Zardoya R, Posada D, (2005) ProtTest: selection of best-fit models of protein evolution. Bioinformatics 21: 2104-2105.
    • (2005) Bioinformatics , vol.21 , pp. 2104-2105
    • Abascal, F.1    Zardoya, R.2    Posada, D.3
  • 35
    • 77950806408 scopus 로고    scopus 로고
    • New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0
    • Guindon S, Dufayard JF, Lefort V, Anisimova M, Hordijk W, et al. (2010) New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0. Syst Biol 59: 307-321.
    • (2010) Syst Biol , vol.59 , pp. 307-321
    • Guindon, S.1    Dufayard, J.F.2    Lefort, V.3    Anisimova, M.4    Hordijk, W.5
  • 36
    • 80052014395 scopus 로고    scopus 로고
    • Survey of branch support methods demonstrates accuracy, power, and robustness of fast likelihood-based approximation schemes
    • Anisimova M, Gil M, Dufayard JF, Dessimoz C, Gascuel O, (2011) Survey of branch support methods demonstrates accuracy, power, and robustness of fast likelihood-based approximation schemes. Syst Biol 60: 685-699.
    • (2011) Syst Biol , vol.60 , pp. 685-699
    • Anisimova, M.1    Gil, M.2    Dufayard, J.F.3    Dessimoz, C.4    Gascuel, O.5
  • 37
    • 45849154166 scopus 로고    scopus 로고
    • An improved general amino acid replacement matrix
    • Le SQ, Gascuel O, (2008) An improved general amino acid replacement matrix. Mol Biol Evol 25: 1307-1320.
    • (2008) Mol Biol Evol , vol.25 , pp. 1307-1320
    • Le, S.Q.1    Gascuel, O.2
  • 38
    • 25444448501 scopus 로고    scopus 로고
    • SeqDoC: rapid SNP and mutation detection by direct comparison of DNA sequence chromatograms
    • Crowe ML, (2005) SeqDoC: rapid SNP and mutation detection by direct comparison of DNA sequence chromatograms. BMC Bioinformatics 6: 133.
    • (2005) BMC Bioinformatics , vol.6 , pp. 133
    • Crowe, M.L.1
  • 39
    • 0016197604 scopus 로고
    • Amino acid difference formula to help explain protein evolution
    • Grantham R, (1974) Amino acid difference formula to help explain protein evolution. Science 185: 862-864.
    • (1974) Science , vol.185 , pp. 862-864
    • Grantham, R.1
  • 40
    • 63449139456 scopus 로고    scopus 로고
    • Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding
    • Aller SG, Yu J, Ward A, Weng Y, Chittaboina S, et al. (2009) Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. Science 323: 1718-1722.
    • (2009) Science , vol.323 , pp. 1718-1722
    • Aller, S.G.1    Yu, J.2    Ward, A.3    Weng, Y.4    Chittaboina, S.5
  • 41
    • 64149097786 scopus 로고    scopus 로고
    • The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments
    • Bustin SA, Benes V, Garson JA, Hellemans J, Huggett J, et al. (2009) The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin Chem 55: 611-622.
    • (2009) Clin Chem , vol.55 , pp. 611-622
    • Bustin, S.A.1    Benes, V.2    Garson, J.A.3    Hellemans, J.4    Huggett, J.5
  • 42
    • 45449087921 scopus 로고    scopus 로고
    • qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data
    • Hellemans J, Mortier G, De Paepe A, Speleman F, Vandesompele J, (2007) qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data. Genome Biol 8: R19.
    • (2007) Genome Biol , vol.8
    • Hellemans, J.1    Mortier, G.2    De Paepe, A.3    Speleman, F.4    Vandesompele, J.5
  • 43
    • 34250390593 scopus 로고
    • Propagation of Electrical Activity in the Nerve Cord and Muscle Syncytium of the Nematode Ascaris lumbricoides
    • Weisblat DA, Russell RL, (1976) Propagation of Electrical Activity in the Nerve Cord and Muscle Syncytium of the Nematode Ascaris lumbricoides. J Comp Physiol 107: 293-307.
    • (1976) J Comp Physiol , vol.107 , pp. 293-307
    • Weisblat, D.A.1    Russell, R.L.2
  • 44
    • 0023659440 scopus 로고
    • A trans-spliced leader sequence on actin mRNA in C. elegans
    • Krause M, Hirsh D, (1987) A trans-spliced leader sequence on actin mRNA in C. elegans. Cell 49: 753-761.
    • (1987) Cell , vol.49 , pp. 753-761
    • Krause, M.1    Hirsh, D.2
  • 47
    • 47749135637 scopus 로고    scopus 로고
    • Ivermectin resistance in Onchocerca volvulus: toward a genetic basis
    • Lustigman S, McCarter JP, (2007) Ivermectin resistance in Onchocerca volvulus: toward a genetic basis. PLoS Negl Trop Dis 1: e76.
    • (2007) PLoS Negl Trop Dis , vol.1
    • Lustigman, S.1    McCarter, J.P.2
  • 48
    • 65549140175 scopus 로고    scopus 로고
    • Assays to detect beta-tubulin codon 200 polymorphism in Trichuris trichiura and Ascaris lumbricoides
    • Diawara A, Drake LJ, Suswillo RR, Kihara J, Bundy DA, et al. (2009) Assays to detect beta-tubulin codon 200 polymorphism in Trichuris trichiura and Ascaris lumbricoides. PLoS Negl Trop Dis 3: e397.
    • (2009) PLoS Negl Trop Dis , vol.3
    • Diawara, A.1    Drake, L.J.2    Suswillo, R.R.3    Kihara, J.4    Bundy, D.A.5
  • 49
    • 22844449116 scopus 로고    scopus 로고
    • Genomic organization and effects of ivermectin selection on Onchocerca volvulus P-glycoprotein
    • Ardelli BF, Guerriero SB, Prichard RK, (2005) Genomic organization and effects of ivermectin selection on Onchocerca volvulus P-glycoprotein. Mol Biochem Parasitol 143: 58-66.
    • (2005) Mol Biochem Parasitol , vol.143 , pp. 58-66
    • Ardelli, B.F.1    Guerriero, S.B.2    Prichard, R.K.3
  • 50
    • 7444224600 scopus 로고    scopus 로고
    • Expression analysis of ABC transporters reveals differential functions of tandemly duplicated genes in Caenorhabditis elegans
    • Zhao Z, Sheps JA, Ling V, Fang LL, Baillie DL, (2004) Expression analysis of ABC transporters reveals differential functions of tandemly duplicated genes in Caenorhabditis elegans. J Mol Biol 344: 409-417.
    • (2004) J Mol Biol , vol.344 , pp. 409-417
    • Zhao, Z.1    Sheps, J.A.2    Ling, V.3    Fang, L.L.4    Baillie, D.L.5
  • 51
    • 0033534534 scopus 로고    scopus 로고
    • Molecular mechanisms of bacterial virulence elucidated using a Pseudomonas aeruginosa-Caenorhabditis elegans pathogenesis model
    • Mahajan-Miklos S, Tan MW, Rahme LG, Ausubel FM, (1999) Molecular mechanisms of bacterial virulence elucidated using a Pseudomonas aeruginosa-Caenorhabditis elegans pathogenesis model. Cell 96: 47-56.
    • (1999) Cell , vol.96 , pp. 47-56
    • Mahajan-Miklos, S.1    Tan, M.W.2    Rahme, L.G.3    Ausubel, F.M.4
  • 52
    • 83955165411 scopus 로고    scopus 로고
    • Ivermectin induces P-glycoprotein expression and function through mRNA stabilization in murine hepatocyte cell line
    • Menez C, Mselli-Lakhal L, Foucaud-Vignault M, Balaguer P, Alvinerie M, et al. (2011) Ivermectin induces P-glycoprotein expression and function through mRNA stabilization in murine hepatocyte cell line. Biochem Pharmacol 83: 269-278.
    • (2011) Biochem Pharmacol , vol.83 , pp. 269-278
    • Menez, C.1    Mselli-Lakhal, L.2    Foucaud-Vignault, M.3    Balaguer, P.4    Alvinerie, M.5
  • 53
    • 78049368057 scopus 로고    scopus 로고
    • Analysis of multiyear studies in horses in Kentucky to ascertain whether counts of eggs and larvae per gram of feces are reliable indicators of numbers of strongyles and ascarids present
    • Nielsen MK, Baptiste KE, Tolliver SC, Collins SS, Lyons ET, (2010) Analysis of multiyear studies in horses in Kentucky to ascertain whether counts of eggs and larvae per gram of feces are reliable indicators of numbers of strongyles and ascarids present. Vet Parasitol 174: 77-84.
    • (2010) Vet Parasitol , vol.174 , pp. 77-84
    • Nielsen, M.K.1    Baptiste, K.E.2    Tolliver, S.C.3    Collins, S.S.4    Lyons, E.T.5
  • 54
    • 63449097953 scopus 로고    scopus 로고
    • Molecular detection of benzimidazole resistance in Haemonchus contortus using real-time PCR and pyrosequencing
    • von Samson-Himmelstjerna G, Walsh TK, Donnan AA, Carriere S, Jackson F, et al. (2009) Molecular detection of benzimidazole resistance in Haemonchus contortus using real-time PCR and pyrosequencing. Parasitology 136: 349-358.
    • (2009) Parasitology , vol.136 , pp. 349-358
    • von Samson-Himmelstjerna, G.1    Walsh, T.K.2    Donnan, A.A.3    Carriere, S.4    Jackson, F.5
  • 55
    • 0141649567 scopus 로고    scopus 로고
    • Detection of P-glycoprotein-mediated multidrug resistance against anthelmintics in Haemonchus contortus using anti-human mdr1 monoclonal antibodies
    • Kerboeuf D, Guegnard F, Vern YL, (2003) Detection of P-glycoprotein-mediated multidrug resistance against anthelmintics in Haemonchus contortus using anti-human mdr1 monoclonal antibodies. Parasitol Res 91: 79-85.
    • (2003) Parasitol Res , vol.91 , pp. 79-85
    • Kerboeuf, D.1    Guegnard, F.2    Vern, Y.L.3
  • 57
    • 79952840248 scopus 로고    scopus 로고
    • Correlation between loss of efficacy of macrocyclic lactone heartworm anthelmintics and P-glycoprotein genotype
    • Bourguinat C, Keller K, Blagburn B, Schenker R, Geary TG, et al. (2011) Correlation between loss of efficacy of macrocyclic lactone heartworm anthelmintics and P-glycoprotein genotype. Vet Parasitol 176: 374-381.
    • (2011) Vet Parasitol , vol.176 , pp. 374-381
    • Bourguinat, C.1    Keller, K.2    Blagburn, B.3    Schenker, R.4    Geary, T.G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.