메뉴 건너뛰기




Volumn 136, Issue 3, 2009, Pages 349-358

Molecular detection of benzimidazole resistance in Haemonchus contortus using real-time PCR and pyrosequencing

Author keywords

Anthelmintic resistance; Nematode; Single nucleotide polymorphism; Thiabendazole; Trichostrongyle

Indexed keywords

BENZIMIDAZOLE; BETA TUBULIN; TIABENDAZOLE; ANTHELMINTIC AGENT; BENZIMIDAZOLE DERIVATIVE; HELMINTH DNA; TUBULIN;

EID: 63449097953     PISSN: 00311820     EISSN: 14698161     Source Type: Journal    
DOI: 10.1017/S003118200800543X     Document Type: Article
Times cited : (124)

References (41)
  • 1
    • 48949118019 scopus 로고    scopus 로고
    • Controlling soil-transmitted helminthiasis in pre-school-age children through preventive chemotherapy
    • DOI 10.1371/journal.pntd.0000126
    • Albonico, M., Allen, H., Chitsulo, L., Engels, D., Gabrielli, A.-F. and Savioli, L. (2008). Controlling soil-transmitted helminthiasis in pre-school-age children through preventive chemotherapy. PLoS Neglected Tropical Diseases 2, e126. (Pubitemid 352002934)
    • (2008) PLoS Neglected Tropical Diseases , vol.2 , Issue.3
    • Albonico, M.1    Allen, H.2    Chitsulo, L.3    Engels, D.4    Gabrielli, A.-F.5    Savioli, L.6
  • 2
    • 6044246292 scopus 로고    scopus 로고
    • Monitoring drug efficacy and early detection of drug resistance in human soil-transmitted nematodes: A pressing public health agenda for helminth control
    • DOI 10.1016/j.ijpara.2004.08.001, PII S0020751904001651
    • Albonico, M., Engels, D. and Savioli, L. (2004a). Monitoring drug efficacy and early detection of drug resistance in human soil-transmitted nematodes: a pressing public health agenda for helminth control. International Journal for Parasitology 34, 1205-1210. (Pubitemid 39382392)
    • (2004) International Journal for Parasitology , vol.34 , Issue.11 , pp. 1205-1210
    • Albonico, M.1    Engels, D.2    Savioli, L.3
  • 3
    • 1542315322 scopus 로고    scopus 로고
    • Molecular analysis of the beta-tubulin gene of human hookworms as a basis for possible benzimidazole resistance on Pemba Island
    • DOI 10.1016/j.molbiopara.2003.12.008, PII S0166685103003785
    • Albonico, M., Wright, V. and Bickle, Q. (2004b). Molecular analysis of the beta-tubulin gene of human hookworms as a basis for possible benzimidazole resistance on Pemba Island. Molecular and Biochemical Parasitology 134, 281-284. (Pubitemid 38299369)
    • (2004) Molecular and Biochemical Parasitology , vol.134 , Issue.2 , pp. 281-284
    • Albonico, M.1    Wright, V.2    Bickle, Q.3
  • 4
    • 17444404976 scopus 로고    scopus 로고
    • Real time PCR for the diagnosis of benzimidazole resistance in trichostrongylids of sheep
    • DOI 10.1016/j.vetpar.2005.02.004
    • Alvarez-Sanchez, M. A., Perez-Garcia, J., Cruz-Rojo, M. A. and Rojo-Vazquez, F. A. (2005). Real time PCR for the diagnosis of benzimidazole resistance in trichostrongylids of sheep. Veterinary Parasitology 129, 291-298. (Pubitemid 40544624)
    • (2005) Veterinary Parasitology , vol.129 , Issue.3-4 , pp. 291-298
    • Alvarez-Sanchez, M.A.1    Perez-Garcia, J.2    Cruz-Rojo, M.A.3    Rojo-Vazquez, F.A.4
  • 5
    • 0035113736 scopus 로고    scopus 로고
    • Locked nucleic acid (LNA): Fine-tuning the recognition of DNA and RNA
    • DOI 10.1016/S1074-5521(00)00058-2, PII S1074552100000582
    • Braasch, D. A. and Corey, D. R. (2001). Locked nucleic acid (LNA): fine-tuning the recognition of DNA and RNA. Chemistry & Biology 8, 1-7. (Pubitemid 32165807)
    • (2001) Chemistry and Biology , vol.8 , Issue.1 , pp. 1-7
    • Braasch, D.A.1    Corey, D.R.2
  • 6
    • 0026768673 scopus 로고
    • World Association for the Advancement of Veterinary Parasitology (WAAVP) methods for the detection of anthelmintic resistance in nematodes of veterinary importance
    • Coles, G. C., Bauer, C., Borgsteede, F. H. M., Geerts, S., Klei, T. R., Taylor, M. A. and Waller, P. J. (1992). World Association for the Advancement of Veterinary Parasitology (WAAVP) methods for the detection of anthelmintic resistance in nematodes of veterinary importance. Veterinary Parasitology 44, 35-44.
    • (1992) Veterinary Parasitology , vol.44 , pp. 35-44
    • Coles, G.C.1    Bauer, C.2    Borgsteede, F.H.M.3    Geerts, S.4    Klei, T.R.5    Taylor, M.A.6    Waller, P.J.7
  • 8
    • 4344571587 scopus 로고    scopus 로고
    • Beta-tubulin complementary DNA sequence variations observed between cyathostomins from benzimidazole-susceptible and -resistant populations
    • DOI 10.1645/GE3305RN
    • Drogemuller, M., Schnieder, T. and von Samson-Himmelstjerna, G. (2004). Beta-tubulin complementary DNA sequence variations observed between cyathostomins from benzimidazole-susceptible and -resistant populations. Journal of Parasitology 90, 868-870. (Pubitemid 39128750)
    • (2004) Journal of Parasitology , vol.90 , Issue.4 , pp. 868-870
    • Drogemuller, M.1    Schnieder, T.2    Von Samson-Himmelstjerna, G.3
  • 9
    • 0030222102 scopus 로고    scopus 로고
    • Sequences of beta-tubulin cDNA from benzimidazole- Susceptible and -resistant strains of Teladorsagia circumcincta, a nematode parasite of small ruminants
    • DOI 10.1016/0166-6851(96)02664-3
    • Elard, L., Comes, A. M. and Humbert, J. F. (1996). Sequences of beta-tubulin cDNA from benzimidazolesusceptible and -resistant strains of Telodorsagia circumcincta, a nematode parasite of small ruminants. Molecular and Biochemical Parasitology 79, 249-253. (Pubitemid 26241898)
    • (1996) Molecular and Biochemical Parasitology , vol.79 , Issue.2 , pp. 249-253
    • Elard, L.1    Comes, A.M.2    Humbert, J.F.3
  • 10
    • 0032935415 scopus 로고    scopus 로고
    • Importance of the mutation of amino acid 200 of the isotype 1 beta- Tubulin gene in the benzimidazole resistance of the small-ruminant parasite Teladorsagia circumcincta
    • DOI 10.1007/s004360050577
    • Elard, L. and Humbert, J. F. (1999). Importance of the mutation of amino acid 200 of the isotype 1 beta-tubulin gene in the benzimidazole resistance of the small ruminant parasite Teladorsagia circumcincta. Parasitology Research 85, 452-456. (Pubitemid 29205209)
    • (1999) Parasitology Research , vol.85 , Issue.6 , pp. 452-456
    • Elard, L.1    Humbert, J.F.2
  • 12
    • 33847053644 scopus 로고    scopus 로고
    • Phenotyping and genotyping of Haemonchus contortus isolates reveals a new putative candidate mutation for benzimidazole resistance in nematodes
    • DOI 10.1016/j.vetpar.2006.10.003, PII S0304401706005802
    • Ghisi, M., Kaminsky, R. and Maser, P. (2007). Phenotyping and genotyping of Haemonchus contortus isolates reveals a new putative candidate mutation for benzimidazole resistance in nematodes. Veterinary Parasitology 144, 313-320. (Pubitemid 46273202)
    • (2007) Veterinary Parasitology , vol.144 , Issue.3-4 , pp. 313-320
    • Ghisi, M.1    Kaminsky, R.2    Maser, P.3
  • 13
    • 44349189082 scopus 로고    scopus 로고
    • The role of polymorphisms at β-tubulin isotype 1 codons 167 and 200 in benzimidazole resistance in cyathostomins
    • Hodgkinson, J. E., Clark, H. J., Kaplan, R. M., Lake, S. L. and Matthews, J. B. (2008). The role of polymorphisms at β-tubulin isotype 1 codons 167 and 200 in benzimidazole resistance in cyathostomins. International Journal for Parasitology 38, 1149-1160.
    • (2008) International Journal for Parasitology , vol.38 , pp. 1149-1160
    • Hodgkinson, J.E.1    Clark, H.J.2    Kaplan, R.M.3    Lake, S.L.4    Matthews, J.B.5
  • 14
    • 34547829263 scopus 로고    scopus 로고
    • DNA bar coding and pyrosequencing to identify rare HIV drug resistance mutations
    • DOI 10.1093/nar/gkm435
    • Hoffmann, C., Minkah, N., Leipzig, J., Wang, G., Arens, M. Q., Tebas, P. and Bushman, F. D. (2007). DNA bar coding and pyrosequencing to identify rare HIV drug resistance mutations. Nucleic Acids Research 35, e91. (Pubitemid 47244608)
    • (2007) Nucleic Acids Research , vol.35 , Issue.13
    • Hoffmann, C.1    Minkah, N.2    Leipzig, J.3    Wang, G.4    Arens, M.Q.5    Tebas, P.6    Bushman, F.D.7
  • 15
    • 4444375921 scopus 로고    scopus 로고
    • Drug resistance in nematodes of veterinary importance: A status report
    • Kaplan, R. M. (2004). Drug resistance in nematodes of veterinary importance: a status report. Trends in Parasitology 20, 477-481.
    • (2004) Trends in Parasitology , vol.20 , pp. 477-481
    • Kaplan, R.M.1
  • 17
    • 0000556725 scopus 로고
    • Characterization of mutations in the β-tubulin gene of benomyl-resistant field strains of Venturia inaequalis and other plant pathogenic fungi
    • Koenraadt, H., Somerville, S. C. and Jones, A. L. (1992). Characterization of mutations in the β-tubulin gene of benomyl-resistant field strains of Venturia inaequalis and other plant pathogenic fungi. Phytopathology 82, 1348-1354.
    • (1992) Phytopathology , vol.82 , pp. 1348-1354
    • Koenraadt, H.1    Somerville, S.C.2    Jones, A.L.3
  • 18
    • 0027180349 scopus 로고
    • Effect of selection for benzimidazole resistance in Haemonchus contortus on β-tubulin isotype 1 and isotype 2 genes
    • DOI 10.1006/bbrc.1993.1233
    • Kwa, M. S. G., Kooyman, F. N. J., Boersema, J. H. and Roos, M. H. (1993). Effect of selection for benzimidazole resistance in Haemonchus contortus on β-tubulin isotype-1 and isotype-2 Genes. Biochemical and Biophysical Research Communications 191, 413-419. (Pubitemid 23222651)
    • (1993) Biochemical and Biophysical Research Communications , vol.191 , Issue.2 , pp. 413-419
    • Kwa, M.S.G.1    Kooyman, F.N.J.2    Boersema, J.H.3    Roos, M.H.4
  • 19
    • 0028293748 scopus 로고
    • Benzimidazole resistance in Haemonchus contortus is correlated with a conserved mutation at amino acid 200 in β-tubulin isotype 1
    • DOI 10.1016/0166-6851(94)90066-3
    • Kwa, M. S. G., Veenstra, J. G. and Roos, M. H. (1994). Benzimidazole resistance in Haemonchus contortus is correlated with a conserved mutation in β-tubulin isotype 1. Molecular and Biochemical Parasitology 63, 299-303. (Pubitemid 24073839)
    • (1994) Molecular and Biochemical Parasitology , vol.63 , Issue.2 , pp. 299-303
    • Kwa, M.S.G.1    Veenstra, J.G.2    Roos, M.H.3
  • 20
    • 0028141763 scopus 로고
    • Cloning of a putative inhibitory amino acid receptor subunit from the parasitic nematode Haemonchus contortus
    • Laughton, D. L., Amar, M., Thomas, P., Towner, P., Harris, P., Lunt, G. G. and Wolstenholme, A. J. (1994). Cloning of a putative inhibitory amino acid receptor subunit from the nematode Haemonchus contortus. Receptors and Channels 2, 155-163. (Pubitemid 24262702)
    • (1994) Receptors and Channels , vol.2 , Issue.2 , pp. 155-163
    • Laughton, D.L.1    Amar, M.2    Thomas, P.3    Towner, P.4    Harris, P.5    Lunt, G.G.6    Wolstenholme, A.J.7
  • 21
    • 2142804689 scopus 로고    scopus 로고
    • Identification and Characterization of Benzimidazole Resistance in Monilinia fructicola from Stone Fruit Orchards in California
    • DOI 10.1128/AEM.69.12.7145-7152.2003
    • Ma, Z. H., Yoshimura, M. A. and Michailides, T. J. (2003). Identification and characterization of benzimidazole resistance in Monilinia fructicola from stone fruit orchards in California. Applied and Environmental Microbiology 69, 7145-7152. (Pubitemid 38585363)
    • (2003) Applied and Environmental Microbiology , vol.69 , Issue.12 , pp. 7145-7152
    • Ma, Z.1    Yoshimura, M.A.2    Michailides, T.J.3
  • 22
    • 0024713407 scopus 로고
    • Detecting benzimidazole resistance with fecal egg count reduction tests and in vitro assays
    • Martin, P. J., Anderson, N. and Jarrett, R. G. (1989). Detecting benzimidazole resistance with fecal egg count reduction tests and in vitro assays. Australian Veterinary Journal 66, 236-240.
    • (1989) Australian Veterinary Journal , vol.66 , pp. 236-240
    • Martin, P.J.1    Anderson, N.2    Jarrett, R.G.3
  • 24
    • 38149100064 scopus 로고    scopus 로고
    • Genetic analysis of a relationship between macrocyclic lactone and benzimidazole anthelmintic selection on Haemonchus contortus
    • Mottier, M. D. and Prichard, R. K. (2008). Genetic analysis of a relationship between macrocyclic lactone and benzimidazole anthelmintic selection on Haemonchus contortus. Pharmacogenetics and Genomics 18, 129-140.
    • (2008) Pharmacogenetics and Genomics , vol.18 , pp. 129-140
    • Mottier, M.D.1    Prichard, R.K.2
  • 25
    • 0037310844 scopus 로고    scopus 로고
    • LNA: A versatile tool for therapeutics and genomics
    • DOI 10.1016/S0167-7799(02)00038-0
    • Petersen, M. and Wengel, J. (2003). LNA: a versatile tool for therapeutics and genomics. Trends in Biotechnology 21, 74-81. (Pubitemid 36165007)
    • (2003) Trends in Biotechnology , vol.21 , Issue.2 , pp. 74-81
    • Petersen, M.1    Wengel, J.2
  • 26
    • 0028106141 scopus 로고
    • Anthelmintic resistance
    • Prichard, R. (1994). Anthelmintic resistance. Veterinary Parasitology 54, 259-268.
    • (1994) Veterinary Parasitology , vol.54 , pp. 259-268
    • Prichard, R.1
  • 27
    • 37249014566 scopus 로고    scopus 로고
    • Microsatellite analysis reveals marked genetic differentiation between Haemonchus contortus laboratory isolates and provides a rapid system of genetic fingerprinting
    • DOI 10.1016/j.ijpara.2007.06.008, PII S0020751907002536
    • Redman, E., Packard, E., Grillo, V., Smith, J., Jackson, F. and Gilleard, J. S. (2008). Microsatellite analysis reveals marked genetic differentiation between Haemonchus contortus laboratory isolates and provides a rapid system of genetic fingerprinting. International Journal for Parasitology 38, 111-122. (Pubitemid 350262791)
    • (2008) International Journal for Parasitology , vol.38 , Issue.1 , pp. 111-122
    • Redman, E.1    Packard, E.2    Grillo, V.3    Smith, J.4    Jackson, F.5    Gilleard, J.S.6
  • 28
    • 0030298490 scopus 로고    scopus 로고
    • Real-time DNA sequencing using detection of pyrophosphate release
    • DOI 10.1006/abio.1996.0432
    • Ronaghi, M., Karamohamed, S., Pettersson, B., Uhlen, M. and Nyren, P. (1996). Real-time DNA sequencing using detection of pyrophosphate release. Analytical Biochemistry 242, 84-89. (Pubitemid 26378519)
    • (1996) Analytical Biochemistry , vol.242 , Issue.1 , pp. 84-89
    • Ronaghi, M.1    Karamohamed, S.2    Pettersson, B.3    Uhlen, M.4    Nyren, P.5
  • 29
    • 0032540905 scopus 로고    scopus 로고
    • A sequencing method based on real-time pyrophosphate
    • DOI 10.1126/science.281.5375.363
    • Ronaghi, M., Uhlen, M. and Nyren, P. (1998). A sequencing method based on real-time pyrophosphate. Science 281, 363-365. (Pubitemid 28340773)
    • (1998) Science , vol.281 , Issue.5375 , pp. 363-365
    • Ronaghi, M.1    Uhlen, M.2    Nyren, P.3
  • 30
    • 24644471957 scopus 로고    scopus 로고
    • Detection of benzimidazole resistance-associated mutations in the filarial nematode Wuchereria bancrofti and evidence for selection by albendazole and ivermectin combination treatment
    • Schwab, A. E., Boakye, D. A., Kyelem, D. and Prichard, R. K. (2005). Detection of benzimidazole resistance-associated mutations in the filarial nematode Wuchereria bancrofti and evidence for selection by albendazole and ivermectin combination treatment. American Journal of Tropical Medicine and Hygiene 73, 234-238. (Pubitemid 41278690)
    • (2005) American Journal of Tropical Medicine and Hygiene , vol.73 , Issue.2 , pp. 234-238
    • Schwab, A.E.1    Boakye, D.A.2    Kyelem, D.3    Prichard, R.K.4
  • 31
    • 35348981195 scopus 로고    scopus 로고
    • Characterization of beta-tubulin genes in hookworms and investigation of resistance-associated mutations using real-time PCR
    • DOI 10.1016/j.molbiopara.2007.07.019, PII S0166685107002228
    • Schwenkenbecher, J. M., Albonico, M., Bickle, Q. and Kaplan, R. M. (2007). Characterization of beta-tubulin genes in hookworms and investigation of resistance-associated mutations using real-time PCR. Molecular and Biochemical Parasitology 156, 167-174. (Pubitemid 47600369)
    • (2007) Molecular and Biochemical Parasitology , vol.156 , Issue.2 , pp. 167-174
    • Schwenkenbecher, J.M.1    Albonico, M.2    Bickle, Q.3    Kaplan, R.M.4
  • 32
    • 0037046108 scopus 로고    scopus 로고
    • Mutation in position 167 of isotype 1 beta-tubulin gene of Trichostrongylid nematodes: Role in benzimidazole resistance?
    • Silvestre, A. and Cabaret, J. (2002). Mutation in position 167 of isotype 1 beta-tubulin gene of Trichostrongylid nematodes: role in benzimidazole resistance? Molecular and Biochemical Parasitology 120, 297-300.
    • (2002) Molecular and Biochemical Parasitology , vol.120 , pp. 297-300
    • Silvestre, A.1    Cabaret, J.2
  • 33
    • 0033814756 scopus 로고    scopus 로고
    • A molecular tool for species identification and benzimidazole resistance diagnosis in larval communities of small ruminant parasites
    • DOI 10.1006/expr.2000.4542
    • Silvestre, A. and Humbert, J. F. (2000).Amolecular tool for species identification and benzimidazole resistance diagnosis in larval communities of small ruminant parasites. Experimental Parasitology 95, 271-276. (Pubitemid 30747047)
    • (2000) Experimental Parasitology , vol.95 , Issue.4 , pp. 271-276
    • Silvestre, A.1    Humbert, J.-F.2
  • 34
    • 0038516788 scopus 로고    scopus 로고
    • Pyrosequencing analysis identifies discrete populations of Haemonchus contortus from small ruminants
    • DOI 10.1016/S0020-7519(03)00068-7
    • Troell, K., Mattson, J. G., Alderborn, A. and Hoglund, J. (2003). Pyrosequencing analysis identifies discrete populations of Haemonchus contortus from small ruminants. International Journal for Parasitology 33, 765-771. (Pubitemid 36695028)
    • (2003) International Journal for Parasitology , vol.33 , Issue.7 , pp. 765-771
    • Troell, K.1    Mattsson, J.G.2    Alderborn, A.3    Hoglund, J.4
  • 35
    • 0023802099 scopus 로고
    • Resistance of field strains of Haemonchus contortus to ivermectin, closantel, rafoxanide and the benzimidazoles in South Africa
    • Van Wyk, J. A. and Malan, F. S. (1988). Resistance of field strains of Haemonchus contortus to ivermectin, closantel, rafoxanide and the benzimidazoles in South Africa. Veterinary Record 123, 226-228.
    • (1988) Veterinary Record , vol.123 , pp. 226-228
    • Van Wyk, J.A.1    Malan, F.S.2
  • 36
    • 24044505116 scopus 로고    scopus 로고
    • Will technology provide solutions for drug resistance in veterinary helminths?
    • von Samson-Himmelstjerna, G. and Blackhall, W. (2005). Will technology provide solutions for drug resistance in veterinary helminths? Veterinary Parasitology 132, 223-239.
    • (2005) Veterinary Parasitology , vol.132 , pp. 223-239
    • Von Samson-Himmelstjerna, G.1    Blackhall, W.2
  • 37
    • 0344442864 scopus 로고    scopus 로고
    • TaqMan minor groove binder real-time PCR analysis of beta-tubulin codon 200 polymorphism in small strongyles (Cyathostomin) indicates that the TAC allele is only moderately selected in benzimidazole-resistant populations
    • DOI 10.1017/S0031182003003974
    • von Samson-Himmelstjerna, G., Buschbaum, S., Wirtherle, N., Pape, M. and Schnieder, T. (2003). TaqMan minor groove binder real-time PCR analysis of beta-tubulin codon 200 polymorphism in small strongyles (Cyathostomin) indicates that the TAC allele is only moderately selected in benzimidazole-resistant populations. Parasitology 127, 489-496. (Pubitemid 37452544)
    • (2003) Parasitology , vol.127 , Issue.5 , pp. 489-496
    • Von Samson-Himmelstjerna, G.1    Buschbaum, S.2    Wirtherle, N.3    Pape, M.4    Schnieder, T.5
  • 38
    • 33847332985 scopus 로고    scopus 로고
    • Detection and measurement of benzimidazole resistance alleles in Haemonchus contortus using real-time PCR with locked nucleic acid Taqman probes
    • DOI 10.1016/j.vetpar.2006.10.014, PII S030440170600584X
    • Walsh, T. K., Donnan, A. A., Jackson, F., Skuce, P. and Wolstenholme, A. J. (2007). Detection and measurement of benzimidazole resistance alleles in Haemonchus contortus using real-time PCR with locked nucleic acid Taqman probes. Veterinary Parasitology 144, 304-312. (Pubitemid 46316758)
    • (2007) Veterinary Parasitology , vol.144 , Issue.3-4 , pp. 304-312
    • Walsh, T.K.1    Donnan, A.A.2    Jackson, F.3    Skuce, P.4    Wolstenholme, A.J.5
  • 40
    • 33750931085 scopus 로고    scopus 로고
    • Pyrosequencing, a high-throughput method for detecting single nucleotide polymorphisms in the dihydrofolate reductase and dihydropteroate synthetase genes of Plasmodium falciparum
    • DOI 10.1128/JCM.01209-06
    • Zhou, Z. Y., Poe, A. C., Limor, J., Grady, K. K., Goldman, I., McCollum, A. M., Escalante, A. A., Barnwell, J. W. and Udhayakumar, V. (2006). Pyrosequencing, a high-throughput method for detecting single nucleotide polymorphisms in the dihydrofolate reductase and dihydropteroate synthetase genes of Plasmodium falciparum. Journal of Clinical Microbiology 44, 3900-3910. (Pubitemid 44737226)
    • (2006) Journal of Clinical Microbiology , vol.44 , Issue.11 , pp. 3900-3910
    • Zhou, Z.1    Poe, A.C.2    Limor, J.3    Grady, K.K.4    Goldman, I.5    McCollum, A.M.6    Escalante, A.A.7    Barnwell, J.W.8    Udhayakumar, V.9
  • 41
    • 34248224931 scopus 로고    scopus 로고
    • Use of pyrosequencing to identify point mutations in domain V of 23S rRNA genes of linezolid-resistant Staphylococcus aureus and Staphylococcus epidermidis
    • DOI 10.1007/s10096-007-0261-0
    • Zhu, W., Tenover, F. C., Limor, J., Lonsway, D., Prince, D., Dunne, W. M. and Patel, J. B. (2007). Use of pyrosequencing to identify point mutations in domain V of 23S rRNA genes of linezolid-resistant Staphylococcus aureus and Staphylococcus epidermidis. European Journal of Clinical Microbiology & Infectious Disease 26, 161-165. (Pubitemid 46723486)
    • (2006) European Journal of Clinical Microbiology and Infectious Diseases , vol.26 , Issue.3 , pp. 161-165
    • Zhu, W.1    Tenover, F.C.2    Limor, J.3    Lonsway, D.4    Prince, D.5    Dunne Jr., W.M.6    Patel, J.B.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.