Pharmacology of anthelmintic resistance

Parasitology Today

Volumn 15, Issue 4, 1999, Pages 141-146

  Sangster, N C ^b   Gill, J ^a  

^a MICROBIAL SCREENING TECHNOLOGIES PTY LTD   (Australia)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTHELMINTIC AGENT; AVERMECTIN; BENZIMIDAZOLE DERIVATIVE; CLOSANTEL; HYCANTHONE; IVERMECTIN; LEVAMISOLE; MILBEMYCIN; PHENOTHIAZINE DERIVATIVE; PIPERAZINE; PRAZIQUANTEL; PYRANTEL; TRICLABENDAZOLE;

AGRICULTURE; BIOASSAY; CATTLE; DRUG MECHANISM; HELMINTHIASIS; HORSE; HUMAN; LARVAL DEVELOPMENT; NEMATODE; NONHUMAN; PARASITE ISOLATION; POLYMERASE CHAIN REACTION; REVIEW; SHEEP; SWINE; VETERINARY MEDICINE;

ANIMALS; ANTHELMINTICS; BENZIMIDAZOLES; CATTLE; DRUG RESISTANCE; HAEMONCHIASIS; HAEMONCHUS; HORSES; HUMANS; IVERMECTIN; LEVAMISOLE; SHEEP; SHEEP DISEASES; SWINE; TRICHOSTRONGYLOIDIASIS; TRICHOSTRONGYLUS;

ANIMALIA; BOS TAURUS; EQUUS CABALLUS; NEMATODA; OVIS ARIES; SUS SCROFA;

EID: 0004371005     PISSN: 01694758     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-4758(99)01413-1     Document Type: Review

References (62)

1. Osol A. Gould Medical Dictionary. 1972;McGraw-Hill Book Company.
2. Hennessy D.R. The disposition of antiparasitic drugs in relation to the development of resistance by parasites of livestock. Acta Trop. 56:1994;125-141.
3. Dobson R.J., Le Jambre L., Gill J.H. Management of anthelmintic resistance: inheritance of resistance and selection with persistent drugs. Int. J. Parasitol. 26:1996;993-1000.
4. Prichard R.K.et al. The problem of anthelmintic resistance in nematodes. Aust. Vet. J. 56:1980;239-251.
5. Shoop W.L. Ivermectin resistance. Parasitol. Today. 9:1993;154-159.
6. Conder G.A., Campbell W.C. Chemotherapy of nematode infections of veterinary importance, with special reference to drug resistance. Adv. Parasitol. 35:1995;1-84.
7. Varady M.et al. In vitro characterisation of lines of Oesophagostomum dentatum selected or not selected for resistance to pyrantel, levamisole and ivermectin. Int. J. Parasitol. 27:1997;77-81.
8. Ihler C.F. A field survey on anthelmintic resistance in equine small strongyles in Norway. Acta Vet. Scand. 36:1995;135-143.
9. Chapman M.R.et al. Identification and characterization of a pyrantel pamoate resistant cyathostome population. Vet. Parasitol. 66:1996;205-212.
10. Cioli D., Pica-Mattoccia L., Archer S. Antischistosomal drugs: past, present . . . and future? Pharmacol. Ther. 68:1995;35-85.
11. Swan N.et al. A field case of ivermectin resistance in Ostertagia of sheep. Aust. Vet. J. 71:1994;302-303.
12. Waller P.J.et al. The prevalence of anthelmintic resistance in nematode parasites of sheep in southern Latin America: general overview. Vet. Parasitol. 62:1996;181-187.
13. Overend D.J., Bowen F.L. Resistance of Fasciola hepatica to triclabendazole. Aust. Vet. J. 72:1995;275-276.
14. Vermunt J.J., West D.M., Pomroy W.E. Multiple resistance to ivermectin and oxfendazole in Cooperia species of cattle in New Zealand. Vet. Rec. 137:1995;43-45.
15. Geerts S., Coles G.C., Gryseels B. Anthelmintic resistance in human helminths: learning from the problems with worm control in livestock. Parasitol. Today. 13:1997;149-151.
16. Savioli L.et al. Anthelmintic resistance in human helminths: learning from the problems with worm control in livestock - reply. Parasitol. Today. 13:1997;156.
17. Gill J.H., Lacey E. Avermectin resistance in trichostrongyloid nematodes. Int. J. Parasitol. 28:1998;863-877.
18. Sangster N.C. Pharmacology of anthelmintic resistance. Parasitology. 113:1996;S201-S216.
19. Martin P.J. Boray J.C., Martin P.J., Roush R.T. Resistance of Parasites to Antiparasitic Drugs. 1990;129-139 MSD, AGVET Rahway.
20. Stelma F.F.et al. Efficacy and side effects of praziquantel in an epidemic focus of Schistosoma mansoni. J. Trop. Med. Hyg. 53:1995;167-170.
21. Barnes E.H., Dobson R.J. Population dynamics of Trichostrongylus colubriformis in sheep: computer model to simulate grazing systems and the evolution of anthelmintic resistance. Int. J. Parasitol. 20:1990;823-831.
22. Martin P.J., Anderson N., Jarrett R.G. Detecting benzimidazole resistance with faecal egg count reduction tests and in vitro assays. Aust. Vet. J. 66:1989;236-240.
23. Fallon P.G.et al. Schistosome resistance to praziquantel: fact or artifact? Parasitol. Today. 12:1996;316-320.
24. Lacey E.et al. Boray J.C., Martin P.J., Roush R.T. Resistance of Parasites to Antiparasitic Drugs. 1990;177-184 MSD AGVET Rahway.
25. Gill J.H.et al. Avermectin inhibition of larval development in Haemonchus contortus - effects of ivermectin resistance. Int. J. Parasitol. 25:1995;463-470.
26. Lacey E. The role of the cytoskeletal protein, tubulin, in the mode of action and mechanism of drug resistance to benzimidazoles. Int. J. Parasitol. 18:1988;885-936.
27. Lacey E., Gill J.H. Biochemistry of benzimidazole resistance. Acta Trop. 56:1994;245-262.
28. Roos M.H., Kwa M.S.G., Grant W.N. New genetic and practical implications of selection for anthelmintic resistance in parasitic nematodes. Parasitol. Today. 11:1995;148-150.
29. Le Jambre L.F., Southcott W.H., Dash K.M. Resistance of selected lines of Haemonchus contortus to thiabendazole, morantel tartrate and levamisole. Int. J. Parasitol. 6:1976;217-222.
30. Sangster N.C., Prichard R.K., Lacey E. Tubulin and benzimidazole-resistance in Trichostrongylus colubriformis (Nematoda). J. Parasitol. 71:1985;645-651.
31. Lacey E., Prichard R.K. Interactions of benzimidazoles (BZ) with tubulin from BZ-sensitive and BZ-resistant isolates of Haemonchus contortus. Mol. Biochem. Parasitol. 19:1986;171-181.
32. Lacey E.et al. Further investigations of the primary mechanisms of benzimidazole resistance in Haemonchus contortus. Int. J. Parasitol. 17:1987;1421-1429.
33. Lacey E., Snowdon K. A routine diagnostic assay for the detection of benzimidazole resistance in parasitic nematodes using tritiated benzimidazole carbamates. Vet. Parasitol. 27:1988;309-324.
34. Kwa M.S.G.et al. Beta-tubulin genes from the parasitic nematode Haemonchus contortus modulate drug resistance in Caenorhabditis elegans. J. Mol. Biol. 246:1995;500-510.
35. Brenner S. The genetics of Caenorhabditis elegans. Genetics. 77:1974;71-94.
36. Sangster N.C.et al. Trichostrongylus colubriformis and Ostertagia circumcincta resistant to levamisole, morantel tartrate and thiabendazole: occurence of field strains. Res. Vet. Sci. 27:1979;106-110.
37. Lewis J.A.et al. Levamisole-resistant mutants of the nematode Caenorhabditis appear to lack pharmacological acetylcholine receptors. Neuroscience. 5:1980;967-989.
38. Lewis J.A.et al. Cholinergic receptor mutants of the nematode Caenorhabditis elegans. J. Neurosci. 7:1987;3059-3071.
39. Fleming J.T.et al. Caenorhabditis elegans levamisole resistance genes lev-1, unc-29, and unc-38 encode functional nicotinic acetylcholine receptor subunits. J. Neurosci. 17:1997;5843-5857.
40. 3H]m-aminolevamisole to receptors in levamisole-susceptible and -resistant Haemonchus contortus. Int. J. Parasitol. 28:1998;707-717.
41. Wiley L.J.et al. Cloning and sequence analysis of the candidate nicotinic acetylcholine receptor alpha subunit gene tar-1 from Trichostrongylus colubriformis. Gene. 182:1996;97-100.
42. Hoekstra R.et al. Characterization of an acetylcholine receptor gene of Haemonchus contortus in relation to levamisole resistance. Mol. Biochem. Parasitol. 84:1997;179-187.
43. Martin R.J.et al. Heterogeneous levamisole receptors: a single-channel study of nicotinic acetylcholine receptors from Oesophagostomum dentatum. Eur. J. Pharmacol. 322:1997;249-257.
44. Shoop W.L.et al. Natural resistance to avermectins and milbemycins: oral activity of ivermectin and moxidectin against ivermectin-resistant and -susceptible nematodes. Vet. Rec. 133:1993;445-447.
45. Conder G.A., Thompson D.P., Johnson S.S. Demonstration of co-resistance of Haemonchus contortus to ivermectin and moxidectin. Vet. Rec. 132:1993;651-652.
46. Le Jambre L.F.et al. Characterisation of an avermectin resistant strain of Australian Haemonchus contortus. Int. J. Parasitol. 25:1995;691-698.
47. Arena J.P.et al. The mechanism of action of avermectins in Caenorhabditis elegans: correlation between activation of glutamate-sensitive chloride current, membrane binding, and biological activity. J. Parasitol. 81:1995;286-294.
48. Cully D.F.et al. Molecular biology and electrophysiology of glutamate-gated chloride channels of invertebrates. Parasitology. 113:1996;S191.
49. Dent J.A., Davis M.W., Avery L. avr-15 encodes a chloride channel subunit that mediates inhibitory glutamatergic neurotransmission and ivermectin sensitivity in Caenorhabditis elegans. EMBO J. 16:1997;5867-5879.
50. Laughton D.L., Lunt G.G., Wolstenholme A.J. Reporter gene constructs suggest that the Caenorhabditis elegans avermectin receptor beta-subunit is expressed solely in the pharynx. J. Exp. Biol. 200:1997;1509-1514.
51. Avery L., Horvitz H.R. Effects of starvation and neuroactive drugs on feeding in Caenorhabditis elegans. J. Exp. Zool. 253:1990;263-270.
52. Prichard R.K. Anthelmintic resistance. Int. J. Parasitol. 54:1994;259-268.
53. Gill J.H.et al. Detection of resistance to ivermectin in Haemonchus contortus. Int. J. Parasitol. 21:1991;771-776.
54. Geary T.G.et al. Haemonchus contortus ivermectin-induced paralysis of the pharynx. Exp. Parasitol. 77:1993;88-96.
55. Rohrer S.P.et al. Ivermectin binding sites in sensitive and resistant Haemonchus contortus. J. Parasitol. 80:1994;493-497.
56. Schaeffer J.M., Haines H.W. Avermectin binding in Caenorhabditis elegans: a two-state model for the avermectin binding site. Biochem. Pharmacol. 38:1989;2329-2338.
57. Cully D.F., Paress P.S. Solubilization and characterization of a high affinity ivermectin binding site from Caenorhabditis elegans. Mol. Pharmacol. 40:1991;326-332.
58. Van Wyk J.A.et al. South African field strains of Haemonchus contortus resistant to the levamisole/morantel group of anthelmintics. Onderstepoort J. Vet. Res. 56:1989;257-262.
59. Gill J.H.et al. Evidence of multiple mechanisms of avermectin resistance in Haemonchus contortus - comparison of selection protocols. Int. J. Parasitol. 28:1998;863-877.
60. Craig T.M., Miller D.K. Resistance by Haemonchus contortus to ivermectin in Angora goats. Vet. Rec. 126:1990;560.
61. Egerton J.R., Suhayda D., Eary C.H. Laboratory selection of Haemonchus contortus for resistance to ivermectin. J. Parasitol. 74:1988;614-617.
62. Clark J.M.et al. Resistance to avermectins: extent, mechanisms, and management implications. Annu. Rev. Entomol. 40:1994;1-30.