Synthesis of 2,5-bis(hetero)aryl 4′-substituted 4,5′- bisoxazoles via copper(I)-catalyzed domino reactions of activated methylene isocyanides with 2-phenyl- and 2-(2-thienyl)-4-[(aryl/heteroaryl)(methylthio) methylene]oxazol-5(4 H)-ones

Journal of Organic Chemistry

Volumn 78, Issue 8, 2013, Pages 3948-3960

  Yugandar, Somaraju ^a   Acharya, Anand ^a   Ila, Hiriyakkanavar ^a  

^a JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER CATALYST; DOMINO PROCESS; DOMINO REACTIONS; ISOCYANIDES; NUCLEOPHILIC RING OPENING; OXAZOLE RING; OXAZOLONES; SEQUENTIAL CONSTRUCTION;

CATALYSIS; COPPER; FUNCTIONAL GROUPS; REACTION KINETICS;

CYANIDES;

2 PHENYL 5 (1 METHYL 2 PYRROLYL) 4' CARBETHOXY 4,5' BISOXAZOLE; 2 PHENYL 5 (1 METHYL 3 INDOLYL) 4' (4 TOSYL) 4,5' BISOXAZOLE; 2 PHENYL 5 (1 METHYL 3 INDOLYL) 4' (N MORPHOLINOCARBONYL) 4,5' BISOXAZOLE; 2 PHENYL 5 (1 METHYL 3 INDOLYL) 4' CARBETHOXY 4,5' BISOXAZOLE; 2 PHENYL 5 (2 THIENYL) 4' (N MORPHOLINOCARBONYL) 4,5' BISOXAZOLE; 2 PHENYL 5 (2 THIENYL) 4' CARBETHOXY 4,5' BISOXAZOLE; 2 PHENYL 5 (3 PYRIDYL) 4' (4 TOSYL) 4,5' BISOXAZOLE; 2 PHENYL 5 (3 PYRIDYL) 4' CARBETHOXY 4,5' BISOXAZOLE; 2 PHENYL 5 (3,4 DIMETHOXYPHENYL) 4' (4 TOSYL) 4,5' BISOXAZOLE; 2 PHENYL 5 (3,4 DIMETHOXYPHENYL) 4' CARBETHOXY 4,5' BISOXAZOLE; 2 PHENYL 5 (4 METHOXYPHENYL) 4' (4 TOSYL) 4,5' BISOXAZOLE; 2 PHENYL 5 (4 METHOXYPHENYL) 4' (N MORPHOLINOCARBONYL) 4,5' BISOXAZOLE; 2 PHENYL 5 (4 METHOXYPHENYL) 4' CARBETHOXY 4,5' BISOXAZOLE; 2,5 BIS(2 THIENYL) 4' (4 TOSYL) 4,5' BISOXAZOLE; 2,5 BIS(2 THIENYL) 4' CARBETHOXY 4,5' BISOXAZOLE; 4 [(METHYLTHIO)(2 THIENYL)METHYLENE] 2 (2 THIENYL)OXAZOL 5(4H)ONE; 4 [BENZO[D][1,3]DIOXOL 5 YL(METHYLTHIO)METHYLENE] 2 (2 THIENYL)OXAZOL 5(4H)ONE; BISOXAZOLE DERIVATIVE; COPPER ION; CUPRIOMETHYLENE ISOCYANIDE DERIVATIVE; CYANIDE; DIAZONAMIDE A; HENNAXAZOLE A; IB 01211; METHYLENE ISOCYANIDE DERIVATIVE; OXAZOLE DERIVATIVE; OXAZOLONE; TELOMESTATIN; ULAPUALIDE A; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ACYLATION; ARTICLE; CATALYSIS; CATALYST; CHEMICAL BOND; CHEMICAL PROCEDURES; CHEMICAL REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; REACTION ANALYSIS; REPRODUCIBILITY; RING OPENING;

EID: 84876527107     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo400317g     Document Type: Article

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