The nitrosated bile acid DNA lesion O6-carboxymethylguanine is a substrate for the human DNA repair protein O6-methylguanine-DNA methyltransferase

Nucleic Acids Research

Volumn 41, Issue 5, 2013, Pages 3047-3055

  Senthong, Pattama ^a   Millington, Christopher L ^b,e   Wilkinson, Oliver J ^b,f   Marriott, Andrew S ^c,g   Watson, Amanda J ^c   Reamtong, Onrapak ^d,h   Eyers, Claire E ^d   Williams, David M ^b   Margison, Geoffrey P ^c,d   Povey, Andrew C ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

^e Institute Génétique et Dévelopement de Rennes   (France)

^f UNIVERSITY OF SUSSEX   (United Kingdom)

^g UNIVERSITY OF LIVERPOOL   (United Kingdom)

^h MAHIDOL UNIVERSITY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

6 O ALKYLGUANINE DNA ALKYLTRANSFERASE; ALKYL GROUP; BILE ACID; CYSTEINE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; OLIGODEOXYRIBONUCLEOTIDE; RESTRICTION ENDONUCLEASE;

ARTICLE; CARCINOGENESIS; COLORECTAL CANCER; DNA DAMAGE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME SYNTHESIS; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MOLECULAR MECHANICS; NITROSATION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

BASE SEQUENCE; BILE ACIDS AND SALTS; CATALYTIC DOMAIN; COLORECTAL NEOPLASMS; DNA ADDUCTS; DNA MODIFICATION METHYLASES; DNA REPAIR ENZYMES; ESCHERICHIA COLI PROTEINS; GTP-BINDING PROTEINS; GUANINE; HUMANS; MEMBRANE PROTEINS; METHYLTRANSFERASES; MOLECULAR WEIGHT; OLIGODEOXYRIBONUCLEOTIDES; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TUMOR SUPPRESSOR PROTEINS;

EID: 84876378991     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gks1476     Document Type: Article

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