Transgenic systems in studies on genotoxicity of alkylating agents: Critical lesions, thresholds and defense mechanisms

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 405, Issue 2, 1998, Pages 179-191

  Kaina, Bernd ^a   Fritz, Gerhard ^a   Ochs, Kirsten ^a   Haas, Simone ^a   Grombacher, Thomas ^a   Dosch, Jörg ^a   Christmann, Markus ^a   Lund, Per ^a   Gregel M, Cornelia ^b   Becker, Klaus ^b,c  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b LEIBNIZ INSTITUTE OF PLANT GENETICS AND CROP PLANT RESEARCH IPK   (Germany)

^c BAYER PHARMA AG   (Germany)

Author keywords

Alkylating agent; Genotoxicity; Transgenic system

Indexed keywords

ALKYLATING AGENT; DIMETHYLBENZ[A]ANTHRACENE; DIMETHYLNITROSAMINE; DNA DIRECTED DNA POLYMERASE BETA; DNA GLYCOSYLTRANSFERASE; ENDONUCLEASE; LIGASE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; METHYLNITROSOUREA; PHORBOL 13 ACETATE 12 MYRISTATE; POLY(ADENOSINE DIPHOSPHATE RIBOSE);

CELL CYCLE; CHROMOSOME ABERRATION; CONFERENCE PAPER; DNA DAMAGE; DNA REPLICATION; EXCISION REPAIR; GENE MUTATION; GENOTOXICITY; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTECTION; SISTER CHROMATID EXCHANGE; TRANSGENE;

ALKYLATING AGENTS; ANIMALS; CELL LINE; HUMANS; MICE; MICE, TRANSGENIC; MUTAGENICITY TESTS; MUTAGENS; NEOPLASMS, EXPERIMENTAL;

EID: 0032552632     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(98)00135-3     Document Type: Conference Paper

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