An approach based on ultra-high pressure liquid chromatography-tandem mass spectrometry to quantify O6-methyl and O6-carboxymethylguanine DNA adducts in intestinal cell lines

Journal of Chromatography A

Volumn 1257, Issue , 2012, Pages 25-33

  Vanden Bussche, J ^a   Moore, S A ^b   Pasmans, F ^a   Kuhnle, G G C ^c,d   Vanhaecke, L ^a  

^a GHENT UNIVERSITY   (Belgium)

^b LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d UNIVERSITY OF READING   (United Kingdom)

Author keywords

Colonocytes; DNA adduct; N nitroso compound; Red meat; UHPLC MS MS

Indexed keywords

COLONOCYTES; DNA ADDUCTS; N-NITROSO COMPOUNDS; RED MEATS; UHPLC-MS/MS;

AMINO ACIDS; CELL CULTURE; CHEMICAL REACTIONS; CHROMATOGRAPHY; DEUTERIUM; FOOD SUPPLY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MEATS; NITROGEN COMPOUNDS; NUCLEOTIDES; POTASSIUM;

DNA;

6 O CARBOXYMETHYLGUANINE; 6 O METHYLGUANINE; DNA; NITROSO DERIVATIVE; POTASSIUM DIAZOACETATE; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN CACO 2; CELL STRAIN HT29; CONTROLLED STUDY; DNA ADDUCT; DNA EXTRACTION; HUMAN; HUMAN CELL; HYDROLYSIS; IN VITRO STUDY; INTESTINE CELL; MONITORING; PRIORITY JOURNAL; PURIFICATION; QUALITY CONTROL; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; VALIDATION PROCESS;

ANIMALS; CACO-2 CELLS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLONIC NEOPLASMS; DNA; DNA ADDUCTS; GUANINE; HT29 CELLS; HUMANS; NITROSO COMPOUNDS; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY;

EID: 84865650943     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2012.07.040     Document Type: Article

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