Promoter hypermethylation of the DNA repair gene O6-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis

Cancer Research

Volumn 61, Issue 12, 2001, Pages 4689-4692

  Esteller, Manel ^a,b   Risques, Rosa Ana ^d   Toyota, Minoru ^c   Capella, Gabriel ^d   Moreno, Victor ^d   Peinado, Miquel Angel ^d   Baylin, Stephen B ^a   Herman, James G ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b Centro Nacional de Investigaciones Oncológicas   (Spain)

^c SAPPORO MEDICAL UNIVERSITY   (Japan)

^d HOSPITAL DURAN I REYNALS   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; CYTOSINE; DINUCLEOTIDE; GUANOSINE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PROTEIN P53; THYMIDINE;

ARTICLE; BASE MISPAIRING; CANCER CELL; CARCINOGENESIS; COLORECTAL CANCER; CONTROLLED STUDY; CPG ISLAND; DEAMINATION; DNA METHYLATION; DNA REPAIR; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROMOTER REGION; TUMOR SUPPRESSOR GENE;

ADENOMA; CARCINOMA; COLORECTAL NEOPLASMS; DNA METHYLATION; DNA REPAIR; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GENES, P53; HUMANS; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; POINT MUTATION; PROMOTER REGIONS (GENETICS);

EID: 0035874892     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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