Synergistic effect of the PDZ and p85β-binding domains of the NS1 protein on virulence of an Avian H5N1 influenza A virus

Journal of Virology

Volumn 87, Issue 9, 2013, Pages 4861-4871

  Fan, Shufang ^a   Macken, Catherine A ^b   Li, Chengjun ^a   Ozawa, Makoto ^a   Goto, Hideo ^c   Iswahyudi, N F N ^d   Nidom, Chairul A ^d   Chen, Hualan ^e   Neumann, Gabriele ^a   Kawaoka, Yoshihiro ^a,c,f,g  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b LOS ALAMOS NATIONAL LABORATORY   (United States)

^c UNIVERSITY OF TOKYO   (Japan)

^d AIRLANGGA UNIVERSITY   (Indonesia)

^e INSTITUTE OF PLANT PROTECTION   (China)

^f JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^g KOBE UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; NONSTRUCTURAL PROTEIN 1; PDZ PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P85BETA; UNCLASSIFIED DRUG;

AMINO ACID ANALYSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CONTROLLED STUDY; EMBRYO; FEMALE; HUMAN; HUMAN CELL; INFLUENZA A (H5N1); INFLUENZA VIRUS A H5N1; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SURVIVAL RATE; SYSTEMIC DISEASE; VIRUS MUTANT; VIRUS MUTATION; VIRUS REPLICATION; VIRUS VIRULENCE;

ANIMALS; CELL LINE; CLASS IA PHOSPHATIDYLINOSITOL 3-KINASE; FEMALE; HEK293 CELLS; HUMANS; INFLUENZA A VIRUS, H5N1 SUBTYPE; INFLUENZA, HUMAN; MICE; MICE, INBRED BALB C; PDZ DOMAINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; VIRAL NONSTRUCTURAL PROTEINS; VIRULENCE;

AVES; AVIAN INFLUENZA VIRUS; INFLUENZA A VIRUS; MUS;

EID: 84876333941     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02608-12     Document Type: Article

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