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Volumn 20, Issue 3, 2013, Pages 208-214

Regulation of systemic iron homeostasis

Author keywords

bone morphogenetic protein; hepcidin; hypoxia; inflammation; iron

Indexed keywords

ANAPLASTIC LYMPHOMA KINASE; BONE MORPHOGENETIC PROTEIN 6; CD71 ANTIGEN; EPIDERMAL GROWTH FACTOR; ERYTHROPOIETIN; FERROPORTIN; HEPCIDIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 6; IRON; MESSENGER RNA; PROCOLLAGEN C PROTEINASE; SCATTER FACTOR; SMAD4 PROTEIN; STAT3 PROTEIN; TRANSFERRIN RECEPTOR 2;

EID: 84876282637     PISSN: 10656251     EISSN: 15317048     Source Type: Journal    
DOI: 10.1097/MOH.0b013e32835f5a47     Document Type: Review
Times cited : (54)

References (52)
  • 1
    • 84861355868 scopus 로고    scopus 로고
    • Hepcidin and iron homeostasis
    • Ganz T, Nemeth E. Hepcidin and iron homeostasis. Biochim Biophys Acta 2012; 1823:1434-1443.
    • (2012) Biochim Biophys Acta , vol.1823 , pp. 1434-1443
    • Ganz, T.1    Nemeth, E.2
  • 2
    • 84864308938 scopus 로고    scopus 로고
    • Ferroportin-mediated iron transport: Expression and regulation
    • Ward DM, Kaplan J. Ferroportin-mediated iron transport: expression and regulation. Biochim Biophys Acta 2012; 1823:1426-1433.
    • (2012) Biochim Biophys Acta , vol.1823 , pp. 1426-1433
    • Ward, D.M.1    Kaplan, J.2
  • 3
    • 84862007363 scopus 로고    scopus 로고
    • Molecular mechanism of hepcidin-mediated ferroportin internalization requires ferroportin lysines, not tyrosines or JAKSTAT
    • Ross SL, Tran L, Winters A, et al. Molecular mechanism of hepcidin-mediated ferroportin internalization requires ferroportin lysines, not tyrosines or JAKSTAT. Cell Metab 2012; 15:905-917.
    • (2012) Cell Metab , vol.15 , pp. 905-917
    • Ross, S.L.1    Tran, L.2    Winters, A.3
  • 4
    • 84862002810 scopus 로고    scopus 로고
    • Hepcidin-induced endocytosis of ferroportin is dependent on ferroportin ubiquitination
    • Qiao B, Sugianto P, Fung E, et al. Hepcidin-induced endocytosis of ferroportin is dependent on ferroportin ubiquitination. Cell Metab 2012; 15:918-924.
    • (2012) Cell Metab , vol.15 , pp. 918-924
    • Qiao, B.1    Sugianto, P.2    Fung, E.3
  • 6
    • 84864316420 scopus 로고    scopus 로고
    • Murine mutants in the study of systemic iron metabolism and its disorders: An update on recent advances
    • Bartnikas TB, Fleming MD, Schmidt PJ. Murine mutants in the study of systemic iron metabolism and its disorders: an update on recent advances. Biochim Biophys Acta 2012; 1823:1444-1450.
    • (2012) Biochim Biophys Acta , vol.1823 , pp. 1444-1450
    • Bartnikas, T.B.1    Fleming, M.D.2    Schmidt, P.J.3
  • 7
    • 79959562083 scopus 로고    scopus 로고
    • Serum and liver iron differently regulate the bone morphogenetic protein 6 (BMP6)-SMAD signaling pathway in mice
    • Corradini E, Meynard D, Wu Q, et al. Serum and liver iron differently regulate the bone morphogenetic protein 6 (BMP6)-SMAD signaling pathway in mice. Hepatology 2011; 54:273-284.
    • (2011) Hepatology , vol.54 , pp. 273-284
    • Corradini, E.1    Meynard, D.2    Wu, Q.3
  • 8
    • 80054101329 scopus 로고    scopus 로고
    • Perturbation of hepcidin expression by BMP type i receptor deletion induces iron overload in mice
    • Steinbicker AU, Bartnikas TB, Lohmeyer LK, et al. Perturbation of hepcidin expression by BMP type I receptor deletion induces iron overload in mice. Blood 2011; 118:4224-4230.
    • (2011) Blood , vol.118 , pp. 4224-4230
    • Steinbicker, A.U.1    Bartnikas, T.B.2    Lohmeyer, L.K.3
  • 9
    • 84857371872 scopus 로고    scopus 로고
    • Hereditary hemochromatosis and transferrin receptor 2
    • Chen J, Enns CA. Hereditary hemochromatosis and transferrin receptor 2. Biochim Biophys Acta 2012; 1820:256-263.
    • (2012) Biochim Biophys Acta , vol.1820 , pp. 256-263
    • Chen, J.1    Enns, C.A.2
  • 10
    • 84861344055 scopus 로고    scopus 로고
    • Transgenic HFE-dependent induction of hepcidin in mice does not require transferrin receptor-2
    • Schmidt PJ, Fleming MD. Transgenic HFE-dependent induction of hepcidin in mice does not require transferrin receptor-2. Am J Hematol 2012; 87:588-595.
    • (2012) Am J Hematol , vol.87 , pp. 588-595
    • Schmidt, P.J.1    Fleming, M.D.2
  • 11
    • 84867578495 scopus 로고    scopus 로고
    • The hemochromatosis proteins HFE, TfR2, and HJV form a membrane-associated protein complex for hepcidin regulation
    • D'Alessio F, Hentze MW, Muckenthaler MU. The hemochromatosis proteins HFE, TfR2, and HJV form a membrane-associated protein complex for hepcidin regulation. J Hepatol 2012; 57:1052-1060.
    • (2012) J Hepatol , vol.57 , pp. 1052-1060
    • D'Alessio, F.1    Hentze, M.W.2    Muckenthaler, M.U.3
  • 12
    • 80052666748 scopus 로고    scopus 로고
    • Iron regulation of hepcidin despite attenuated Smad1,5,8 signaling in mice without transferrin receptor 2 or Hfe
    • Corradini E, Rozier M, Meynard D, et al. Iron regulation of hepcidin despite attenuated Smad1,5,8 signaling in mice without transferrin receptor 2 or Hfe. Gastroenterology 2011; 141:1907-1914.
    • (2011) Gastroenterology , vol.141 , pp. 1907-1914
    • Corradini, E.1    Rozier, M.2    Meynard, D.3
  • 13
    • 79953757053 scopus 로고    scopus 로고
    • Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice
    • Ramos E, Kautz L, Rodriguez R, et al. Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice. Hepatology 2011; 53:1333-1341.
    • (2011) Hepatology , vol.53 , pp. 1333-1341
    • Ramos, E.1    Kautz, L.2    Rodriguez, R.3
  • 14
    • 70349494083 scopus 로고    scopus 로고
    • Bone morphogenetic protein signaling is impaired in an HFE knockout mouse model of hemochromatosis
    • Corradini E, Garuti C, Montosi G, et al. Bone morphogenetic protein signaling is impaired in an HFE knockout mouse model of hemochromatosis. Gastroenterology 2009; 137:1489-1497.
    • (2009) Gastroenterology , vol.137 , pp. 1489-1497
    • Corradini, E.1    Garuti, C.2    Montosi, G.3
  • 15
    • 79953316619 scopus 로고    scopus 로고
    • The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice
    • Castoldi M, Spasic MV, Altamura S, et al. The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice. J Clin Invest 2011; 121:1386-1396.
    • (2011) J Clin Invest , vol.121 , pp. 1386-1396
    • Castoldi, M.1    Spasic, M.V.2    Altamura, S.3
  • 16
    • 77953379428 scopus 로고    scopus 로고
    • Iron-deficiency anemia secondary to mutations in genes controlling hepcidin
    • Cau M, Melis MA, Congiu R, Galanello R. Iron-deficiency anemia secondary to mutations in genes controlling hepcidin. Expert Rev Hematol 2010; 3:205-216.
    • (2010) Expert Rev Hematol , vol.3 , pp. 205-216
    • Cau, M.1    Melis, M.A.2    Congiu, R.3    Galanello, R.4
  • 17
    • 80054840413 scopus 로고    scopus 로고
    • TMPRSS6 rs855791 modulates hepcidin transcription in vitro and serum hepcidin levels in normal individuals
    • Nai A, Pagani A, Silvestri L, et al. TMPRSS6 rs855791 modulates hepcidin transcription in vitro and serum hepcidin levels in normal individuals. Blood 2011; 118:4459-4462.
    • (2011) Blood , vol.118 , pp. 4459-4462
    • Nai, A.1    Pagani, A.2    Silvestri, L.3
  • 18
    • 78751598932 scopus 로고    scopus 로고
    • Regulation of type II transmembrane serine proteinase TMPRSS6 by hypoxia-inducible factors: New link between hypoxia signaling and iron homeostasis
    • Lakhal S, Schodel J, Townsend AR, et al. Regulation of type II transmembrane serine proteinase TMPRSS6 by hypoxia-inducible factors: new link between hypoxia signaling and iron homeostasis. J Biol Chem 2011; 286:4090-4097.
    • (2011) J Biol Chem , vol.286 , pp. 4090-4097
    • Lakhal, S.1    Schodel, J.2    Townsend, A.R.3
  • 19
    • 84861380376 scopus 로고    scopus 로고
    • Matriptase-2 (TMPRSS6) is directly upregulated by hypoxia inducible factor-1: Identification of a hypoxia-responsive element in the TMPRSS6 promoter region
    • Maurer E, Gutschow M, Stirnberg M. Matriptase-2 (TMPRSS6) is directly upregulated by hypoxia inducible factor-1: identification of a hypoxia-responsive element in the TMPRSS6 promoter region. Biol Chem 2012; 393:535-540.
    • (2012) Biol Chem , vol.393 , pp. 535-540
    • Maurer, E.1    Gutschow, M.2    Stirnberg, M.3
  • 20
    • 79551629285 scopus 로고    scopus 로고
    • Suppression of hepatic hepcidin expression in response to acute iron deprivation is associated with an increase of matriptase-2 protein
    • Zhang AS, Anderson SA, Wang J, et al. Suppression of hepatic hepcidin expression in response to acute iron deprivation is associated with an increase of matriptase-2 protein. Blood 2011; 117:1687-1699.
    • (2011) Blood , vol.117 , pp. 1687-1699
    • Zhang, A.S.1    Anderson, S.A.2    Wang, J.3
  • 21
    • 79960674973 scopus 로고    scopus 로고
    • Regulation of TMPRSS6 by BMP6 and iron in human cells and mice
    • Meynard D, Vaja V, Sun CC, et al. Regulation of TMPRSS6 by BMP6 and iron in human cells and mice. Blood 2011; 118:747-756.
    • (2011) Blood , vol.118 , pp. 747-756
    • Meynard, D.1    Vaja, V.2    Sun, C.C.3
  • 22
    • 84867411483 scopus 로고    scopus 로고
    • Neogenin interacts with matriptase-2 to facilitate hemojuvelin cleavage
    • Enns CA, Ahmed R, Zhang AS. Neogenin interacts with matriptase-2 to facilitate hemojuvelin cleavage. J Biol Chem 2012; 287:35104-35117.
    • (2012) J Biol Chem , vol.287 , pp. 35104-35117
    • Enns, C.A.1    Ahmed, R.2    Zhang, A.S.3
  • 23
    • 77951086900 scopus 로고    scopus 로고
    • Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis
    • Lee DH, Zhou LJ, Zhou Z, et al. Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis. Blood 2010; 115:3136-3145.
    • (2010) Blood , vol.115 , pp. 3136-3145
    • Lee, D.H.1    Zhou, L.J.2    Zhou, Z.3
  • 24
    • 80055055193 scopus 로고    scopus 로고
    • Conditional disruption of mouse HFE2 gene: Maintenance of systemic iron homeostasis requires hepatic but not skeletal muscle hemojuvelin
    • Gkouvatsos K, Wagner J, Papanikolaou G, et al. Conditional disruption of mouse HFE2 gene: maintenance of systemic iron homeostasis requires hepatic but not skeletal muscle hemojuvelin. Hepatology 2011; 54:1800-1807.
    • (2011) Hepatology , vol.54 , pp. 1800-1807
    • Gkouvatsos, K.1    Wagner, J.2    Papanikolaou, G.3
  • 25
    • 79959437085 scopus 로고    scopus 로고
    • Skeletal muscle hemojuvelin is dispensable for systemic iron homeostasis
    • Chen W, Huang FW, de Renshaw TB, Andrews NC. Skeletal muscle hemojuvelin is dispensable for systemic iron homeostasis. Blood 2011; 117:6319-6325.
    • (2011) Blood , vol.117 , pp. 6319-6325
    • Chen, W.1    Huang, F.W.2    De Renshaw, T.B.3    Andrews, N.C.4
  • 26
    • 84856700549 scopus 로고    scopus 로고
    • BMPER protein is a negative regulator of hepcidin and is up-regulated in hypotransferrinemic mice
    • Patel N, Masaratana P, Diaz-Castro J, et al. BMPER protein is a negative regulator of hepcidin and is up-regulated in hypotransferrinemic mice. J Biol Chem 2012; 287:4099-4106.
    • (2012) J Biol Chem , vol.287 , pp. 4099-4106
    • Patel, N.1    Masaratana, P.2    Diaz-Castro, J.3
  • 27
    • 84862792124 scopus 로고    scopus 로고
    • Targeting the hepcidin-ferroportin axis to develop new treatment strategies for anemia of chronic disease and anemia of inflammation
    • Sun CC, Vaja V, Babitt JL, Lin HY. Targeting the hepcidin-ferroportin axis to develop new treatment strategies for anemia of chronic disease and anemia of inflammation. Am J Hematol 2012; 87:392-400.
    • (2012) Am J Hematol , vol.87 , pp. 392-400
    • Sun, C.C.1    Vaja, V.2    Babitt, J.L.3    Lin, H.Y.4
  • 28
    • 84868526205 scopus 로고    scopus 로고
    • Hepcidin and the iron-infection axis
    • Drakesmith H, Prentice AM. Hepcidin and the iron-infection axis. Science 2012; 338:768-772.
    • (2012) Science , vol.338 , pp. 768-772
    • Drakesmith, H.1    Prentice, A.M.2
  • 29
    • 33644876815 scopus 로고    scopus 로고
    • A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression
    • Wang RH, Li C, Xu X, et al. A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression. Cell Metab 2005; 2:399-409.
    • (2005) Cell Metab , vol.2 , pp. 399-409
    • Wang, R.H.1    Li, C.2    Xu, X.3
  • 30
    • 79953121575 scopus 로고    scopus 로고
    • Blunted hepcidin response to inflammation in the absence of Hfe and transferrin receptor 2
    • Wallace DF, McDonald CJ, Ostini L, Subramaniam VN. Blunted hepcidin response to inflammation in the absence of Hfe and transferrin receptor 2. Blood 2011; 117:2960-2966.
    • (2011) Blood , vol.117 , pp. 2960-2966
    • Wallace, D.F.1    McDonald, C.J.2    Ostini, L.3    Subramaniam, V.N.4
  • 31
    • 79955980950 scopus 로고    scopus 로고
    • Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation
    • Steinbicker AU, Sachidanandan C, Vonner AJ, et al. Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation. Blood 2011; 117:4915-4923.
    • (2011) Blood , vol.117 , pp. 4915-4923
    • Steinbicker, A.U.1    Sachidanandan, C.2    Vonner, A.J.3
  • 32
    • 80052647221 scopus 로고    scopus 로고
    • Pharmacologic inhibition of hepcidin expression reverses anemia of chronic inflammation in rats
    • Theurl I, Schroll A, Sonnweber T, et al. Pharmacologic inhibition of hepcidin expression reverses anemia of chronic inflammation in rats. Blood 2011; 118:4977-4984.
    • (2011) Blood , vol.118 , pp. 4977-4984
    • Theurl, I.1    Schroll, A.2    Sonnweber, T.3
  • 33
    • 84864053080 scopus 로고    scopus 로고
    • Induction of activin B by inflammatory stimuli up-regulates expression of the iron-regulatory peptide hepcidin through Smad1/5/8 signaling
    • Besson-Fournier C, Latour C, Kautz L, et al. Induction of activin B by inflammatory stimuli up-regulates expression of the iron-regulatory peptide hepcidin through Smad1/5/8 signaling. Blood 2012; 120:431-439.
    • (2012) Blood , vol.120 , pp. 431-439
    • Besson-Fournier, C.1    Latour, C.2    Kautz, L.3
  • 34
    • 80054114689 scopus 로고    scopus 로고
    • Hepcidin regulation by innate immune and infectious stimuli
    • Armitage AE, Eddowes LA, Gileadi U, et al. Hepcidin regulation by innate immune and infectious stimuli. Blood 2011; 118:4129-4139.
    • (2011) Blood , vol.118 , pp. 4129-4139
    • Armitage, A.E.1    Eddowes, L.A.2    Gileadi, U.3
  • 35
    • 84868258078 scopus 로고    scopus 로고
    • Sustained submicromolar H2O2 levels induce hepcidin via signal transducer and activator of transcription 3 (STAT3
    • Millonig G, Ganzleben I, Peccerella T, et al. Sustained submicromolar H2O2 levels induce hepcidin via signal transducer and activator of transcription 3 (STAT3). J Biol Chem 2012; 287:37472-37482.
    • (2012) J Biol Chem , vol.287 , pp. 37472-37482
    • Millonig, G.1    Ganzleben, I.2    Peccerella, T.3
  • 36
    • 80054838641 scopus 로고    scopus 로고
    • Beta-Thalassemia: A model for elucidating the dynamic regulation of ineffective erythropoiesis and iron metabolism
    • Ginzburg Y. Rivella S. beta-Thalassemia: a model for elucidating the dynamic regulation of ineffective erythropoiesis and iron metabolism. Blood 2011; 118:4321-4330.
    • (2011) Blood , vol.118 , pp. 4321-4330
    • Ginzburg, Y.1    Rivella, S.2
  • 37
    • 84871223663 scopus 로고    scopus 로고
    • The murine growth differentiation factor 15 is not essential for systemic iron homeostasis in phlebotomized mice
    • doi:10.3324/haematol.2012.069807 [Epub ahead of print]
    • Casanovas G, Vujic Spasic M, Casu C, et al. The murine growth differentiation factor 15 is not essential for systemic iron homeostasis in phlebotomized mice. Haematologica 2012. doi:10.3324/haematol.2012.069807 [Epub ahead of print]
    • (2012) Haematologica
    • Casanovas, G.1    Vujic Spasic, M.2    Casu, C.3
  • 38
    • 79953108427 scopus 로고    scopus 로고
    • Modulation of hepcidin production during hypoxia-induced erythropoiesis in humans in vivo: Data from the HIGHCARE project
    • Piperno A, Galimberti S, Mariani R, et al. Modulation of hepcidin production during hypoxia-induced erythropoiesis in humans in vivo: data from the HIGHCARE project. Blood 2011; 117:2953-2959.
    • (2011) Blood , vol.117 , pp. 2953-2959
    • Piperno, A.1    Galimberti, S.2    Mariani, R.3
  • 39
    • 84856072239 scopus 로고    scopus 로고
    • Regulation of hepcidin expression at high altitude
    • Talbot NP, Lakhal S, Smith TG, et al. Regulation of hepcidin expression at high altitude. Blood 2012; 119:857-860.
    • (2012) Blood , vol.119 , pp. 857-860
    • Talbot, N.P.1    Lakhal, S.2    Smith, T.G.3
  • 40
    • 81555209768 scopus 로고    scopus 로고
    • Hepcidin: A critical regulator of iron metabolism during hypoxia
    • Hintze KJ, McClung JP. Hepcidin: A critical regulator of iron metabolism during hypoxia. Adv Hematol 2011; 2011:510304.
    • (2011) Adv Hematol , vol.2011 , pp. 510304
    • Hintze, K.J.1    McClung, J.P.2
  • 41
    • 81155149499 scopus 로고    scopus 로고
    • Chuvash polycythemia VHLR200W mutation is associated with down-regulation of hepcidin expression
    • Gordeuk VR, Miasnikova GY, Sergueeva AI, et al. Chuvash polycythemia VHLR200W mutation is associated with down-regulation of hepcidin expression. Blood 2011; 118:5278-5282.
    • (2011) Blood , vol.118 , pp. 5278-5282
    • Gordeuk, V.R.1    Miasnikova, G.Y.2    Sergueeva, A.I.3
  • 42
    • 84870566647 scopus 로고    scopus 로고
    • Hypoxia-inducible factor regulates hepcidin via erythropoietin-induced erythropoiesis
    • Liu Q, Davidoff O, Niss K, Haase VH. Hypoxia-inducible factor regulates hepcidin via erythropoietin-induced erythropoiesis. J Clin Invest 2012; 122: 4635-4644.
    • (2012) J Clin Invest , vol.122 , pp. 4635-4644
    • Liu, Q.1    Davidoff, O.2    Niss, K.3    Haase, V.H.4
  • 43
    • 84862148400 scopus 로고    scopus 로고
    • Hepatic hypoxia-inducible factor-2 down-regulates hepcidin expression in mice through an erythropoietinmediated increase in erythropoiesis
    • Mastrogiannaki M, Matak P,Mathieu JR, et al. Hepatic hypoxia-inducible factor-2 down-regulates hepcidin expression in mice through an erythropoietinmediated increase in erythropoiesis. Haematologica 2012; 97:827-834.
    • (2012) Haematologica , vol.97 , pp. 827-834
    • Mastrogiannaki, M.1    Matak, P.2    Mathieu, J.R.3
  • 44
    • 84868676833 scopus 로고    scopus 로고
    • The hypoxia-inducible factor-C/EBPalpha axis controls ethanol-mediated hepcidin repression
    • Anderson ER, Taylor M, Xue X, et al. The hypoxia-inducible factor-C/EBPalpha axis controls ethanol-mediated hepcidin repression. Mol Cell Biol 2012; 32:4068-4077.
    • (2012) Mol Cell Biol , vol.32 , pp. 4068-4077
    • Anderson, E.R.1    Taylor, M.2    Xue, X.3
  • 45
    • 84868193427 scopus 로고    scopus 로고
    • Estrogen regulates iron homeostasis through governing hepatic hepcidin expression via an estrogen response element
    • Hou Y, Zhang S, Wang L, et al. Estrogen regulates iron homeostasis through governing hepatic hepcidin expression via an estrogen response element. Gene 2012; 511:398-403.
    • (2012) Gene , vol.511 , pp. 398-403
    • Hou, Y.1    Zhang, S.2    Wang, L.3
  • 46
    • 84863827034 scopus 로고    scopus 로고
    • Estrogen regulates hepcidin expression via GPR30-BMP6-dependent signaling in hepatocytes
    • Ikeda Y, Tajima S, Izawa-Ishizawa Y, et al. Estrogen regulates hepcidin expression via GPR30-BMP6-dependent signaling in hepatocytes. PLoS One 2012; 7:e40465.
    • (2012) PLoS One , vol.7
    • Ikeda, Y.1    Tajima, S.2    Izawa-Ishizawa, Y.3
  • 47
    • 84862736353 scopus 로고    scopus 로고
    • 17beta-Estradiol inhibits iron hormone hepcidin through an estrogen responsive element half-site
    • Yang Q, Jian J, Katz S, et al. 17beta-Estradiol inhibits iron hormone hepcidin through an estrogen responsive element half-site. Endocrinology 2012; 153:3170-3178.
    • (2012) Endocrinology , vol.153 , pp. 3170-3178
    • Yang, Q.1    Jian, J.2    Katz, S.3
  • 48
    • 84864450985 scopus 로고    scopus 로고
    • Circulating human hepcidin-25 concentrations display a diurnal rhythm increase with prolonged fasting and are reduced by growth hormone administration
    • Troutt JS, Rudling M, Persson L, et al. Circulating human hepcidin-25 concentrations display a diurnal rhythm, increase with prolonged fasting, and are reduced by growth hormone administration. Clin Chem2012; 58:1225-1232.
    • (2012) Clin Chem , vol.58 , pp. 1225-1232
    • Troutt, J.S.1    Rudling, M.2    Persson, L.3
  • 49
    • 84870472632 scopus 로고    scopus 로고
    • Glucose acts as a regulator of serum iron by increasing serum hepcidin concentrations
    • Aigner E, Felder TK, Oberkofler H, et al. Glucose acts as a regulator of serum iron by increasing serum hepcidin concentrations. J Nutr Biochem 2013; 24:112-117.
    • (2013) J Nutr Biochem , vol.24 , pp. 112-117
    • Aigner, E.1    Felder, T.K.2    Oberkofler, H.3
  • 50
    • 84863531503 scopus 로고    scopus 로고
    • Inhibition of hepcidin transcription by growth factors
    • Goodnough JB, Ramos E, Nemeth E, Ganz T. Inhibition of hepcidin transcription by growth factors. Hepatology 2012; 56:291-299.
    • (2012) Hepatology , vol.56 , pp. 291-299
    • Goodnough, J.B.1    Ramos, E.2    Nemeth, E.3    Ganz, T.4
  • 51
    • 79251567060 scopus 로고    scopus 로고
    • ER stress and iron homeostasis: A new frontier for the UPR
    • Oliveira SJ, de Sousa M, Pinto JP. ER stress and iron homeostasis: a new frontier for the UPR. Biochem Res Int 2011; 2011:896474.
    • (2011) Biochem Res Int , vol.2011 , pp. 896474
    • Oliveira, S.J.1    De Sousa, M.2    Pinto, J.P.3
  • 52
    • 78751696745 scopus 로고    scopus 로고
    • Heparin: A potent inhibitor of hepcidin expression in vitro and in vivo
    • Poli M, Girelli D, Campostrini N, et al. Heparin: a potent inhibitor of hepcidin expression in vitro and in vivo. Blood 2011; 117:997-1004.
    • (2011) Blood , vol.117 , pp. 997-1004
    • Poli, M.1    Girelli, D.2    Campostrini, N.3


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