Matriptase-2 (TMPRSS6) is directly up-regulated by hypoxia inducible factor-1: Identification of a hypoxia-responsive element in the TMPRSS6 promoter region

Biological Chemistry

Volumn 393, Issue 6, 2012, Pages 535-540

  Maurer, Eva ^a   Gütschow, Michael ^a   Stirnberg, Marit ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

hepcidin; iron deficiency; reporter gene assay; transcriptional regulation; type II transmembrane serine protease

Indexed keywords

HEPCIDIN; HYPOXIA INDUCIBLE FACTOR 1; IRON; MATRIPTASE; PROTEIN MATRIPTASE 2; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; BLOOD LEVEL; CONTROLLED STUDY; GENE REPRESSION; HOMEOSTASIS; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOXIA; MUTATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

CELL HYPOXIA; CELL LINE; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IRON; MEMBRANE PROTEINS; RESPONSE ELEMENTS; SERINE ENDOPEPTIDASES; UP-REGULATION;

EID: 84861380376     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/hsz-2011-0221     Document Type: Article

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