Enzymatic conversion of 6-nitroquinoline to the fluorophore 6-aminoquinoline selectively under hypoxic conditions

Chemical Research in Toxicology

Volumn 26, Issue 4, 2013, Pages 555-563

  Rajapakse, Anuruddha ^a   Linder, Collette ^d   Morrison, Ryan D ^c   Sarkar, Ujjal ^a   Leigh, Nathan D ^a   Barnes, Charles L ^a   Daniels, J Scott ^c,d   Gates, Kent S ^a,b  

^a UNIVERSITY OF MISSOURI   (United States)

^b University of Missouri   (United States)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 AMINOQUINOLINE; 6 HYDROXYLAMINOQUINOLINE; 6 NITROQUINOLIN 2(1H) ONE; 6 NITROQUINOLINE; FLUORESCENT DYE; OXYGEN; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG; XANTHINE; XANTHINE OXIDASE;

ARTICLE; ELECTRON; ELECTROSPRAY MASS SPECTROMETRY; ENZYME METABOLISM; ENZYME SYNTHESIS; HYPOXIA; OXIDATION; REDUCTION; ROOM TEMPERATURE;

AMINOQUINOLINES; ANOXIA; NITROQUINOLINES; XANTHINE; XANTHINE OXIDASE;

EID: 84876212712     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx300483z     Document Type: Article

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