DNA base damage by the antitumor agent 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine)

Journal of the American Chemical Society

Volumn 125, Issue 38, 2003, Pages 11607-11615

  Birincioglu, Mustafa ^a,b   Jaruga, Pawel ^a,c   Chowdhury, Goutam ^d   Rodriguez, Henry ^a   Dizdaroglu, Miral ^a   Gates, Kent S ^d  

^a NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

^b INONU UNIVERSITY   (Turkey)

^c University of Marylandw Baltimore County   (United States)

^d UNIVERSITY OF MISSOURI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITUMOR AGENTS;

DNA; GAS CHROMATOGRAPHY; MASS SPECTROMETRY; TOXICITY; TUMORS;

ORGANIC COMPOUNDS;

ANTINEOPLASTIC AGENT; DNA BASE; DOUBLE STRANDED DNA; FORMAMIDE DERIVATIVE; NUCLEOSIDE DERIVATIVE; PURINE DERIVATIVE; PYRIMIDINE DERIVATIVE; TIRAPAZAMINE;

ARTICLE; CELL HYPOXIA; CELL KILLING; DNA DAMAGE; DNA REPLICATION; DRUG CYTOTOXICITY; DRUG TARGETING; GAS CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; SOLID TUMOR; TRANSCRIPTION TERMINATION;

ANTINEOPLASTIC AGENTS; CHROMATOGRAPHY, LIQUID; DNA DAMAGE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; OXIDATION-REDUCTION; PURINE NUCLEOSIDES; TRIAZINES;

EID: 0141757434     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0352146     Document Type: Article

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