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Volumn 18, Issue 6, 2012, Pages 1487-1489

Imaging tumor sensitivity to a bioreductive prodrug: Two for the price of one!

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 NITRO 1H IMIDAZOL 1 YL) N (2,2,3,3,3 PENTAFLUOROPROPYL)ACETAMIDE; 2 (2 NITRO 1H IMIDAZOL 1 YL) N (2,2,3,3,3 PENTAFLUOROPROPYL)ACETAMIDE F 18; ANTINEOPLASTIC AGENT; CEN 209; FLUORINE 18; NITROREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE FERRIHEMOPROTEIN REDUCTASE; TIRAPAZAMINE; TRACER; UNCLASSIFIED DRUG;

EID: 84863272778     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-11-3267     Document Type: Article
Times cited : (7)

References (8)
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    • Wang J, Foehrenbacher A, Su J, Patel R, Hay MP, Hicks KO, et al. The 2-nitroimidazole EF5 is a biomarker for oxidoreductases that activate the bioreductive prodrug CEN-209 under hypoxia. Clin Cancer Res 2012;18:1684-95.
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    • Wang, J.1    Foehrenbacher, A.2    Su, J.3    Patel, R.4    Hay, M.P.5    Hicks, K.O.6
  • 2
    • 79960344338 scopus 로고    scopus 로고
    • Hypoxic modification of radiotherapy in squamous cell carcinoma of the head and neck - A systematic review and meta-analysis
    • Overgaard J. Hypoxic modification of radiotherapy in squamous cell carcinoma of the head and neck - a systematic review and meta-analysis. Radiother Oncol 2011;100:22-32.
    • (2011) Radiother Oncol , vol.100 , pp. 22-32
    • Overgaard, J.1
  • 3
    • 2942590732 scopus 로고    scopus 로고
    • Exploiting tumour hypoxia in cancer treatment
    • Brown JM, Wilson WR. Exploiting tumour hypoxia in cancer treatment. Nat Rev Cancer 2004;4:437-47. (Pubitemid 38745529)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.6 , pp. 437-447
    • Brown, J.M.1    Wilson, W.R.2
  • 4
    • 77954600498 scopus 로고    scopus 로고
    • Tirapazamine, cisplatin, and radiation versus cisplatin and radiation for advanced squamous cell carcinoma of the head and neck (TROG 02.02, HeadSTART): A phase III trial of the Trans-Tasman Radiation Oncology Group
    • Rischin D, Peters LJ, O'Sullivan B, Giralt J, Fisher R, Yuen K, et al. Tirapazamine, cisplatin, and radiation versus cisplatin and radiation for advanced squamous cell carcinoma of the head and neck (TROG 02.02, HeadSTART): a phase III trial of the Trans-Tasman Radiation Oncology Group. J Clin Oncol 2010;28:2989-95.
    • (2010) J Clin Oncol , vol.28 , pp. 2989-2995
    • Rischin, D.1    Peters, L.J.2    O'Sullivan, B.3    Giralt, J.4    Fisher, R.5    Yuen, K.6
  • 5
    • 77954600968 scopus 로고    scopus 로고
    • Critical impact of radiotherapy protocol compliance and quality in the treatment of advanced head and neck cancer: Results from TROG02.02
    • Peters LJ, O'Sullivan B, Giralt J, Fitzgerald TJ, Trotti A, Bernier J, et al. Critical impact of radiotherapy protocol compliance and quality in the treatment of advanced head and neck cancer: results from TROG02.02. J Clin Oncol 2010;28:2996-3001.
    • (2010) J Clin Oncol , vol.28 , pp. 2996-3001
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  • 6
    • 77958060317 scopus 로고    scopus 로고
    • Pharmacokinetic/pharmacodynamic modeling identifies SN30000 and SN29751 as tirapazamine analogues with improved tissue penetration and hypoxic cell killing in tumors
    • Hicks KO, Siim BG, Jaiswal JK, Pruijn FB, Fraser AM, Patel R, et al. Pharmacokinetic/pharmacodynamic modeling identifies SN30000 and SN29751 as tirapazamine analogues with improved tissue penetration and hypoxic cell killing in tumors. Clin Cancer Res 2010;16:4946-57.
    • (2010) Clin Cancer Res , vol.16 , pp. 4946-4957
    • Hicks, K.O.1    Siim, B.G.2    Jaiswal, J.K.3    Pruijn, F.B.4    Fraser, A.M.5    Patel, R.6
  • 7
    • 33646454133 scopus 로고    scopus 로고
    • 18F]-misonidazole positron emission tomography-detected tumor hypoxia in patients with advanced head and neck cancer randomly assigned to chemoradiation with or without tirapazamine: A substudy of Trans-Tasman Radiation Oncology Group Study 98.02
    • 18F]-misonidazole positron emission tomography-detected tumor hypoxia in patients with advanced head and neck cancer randomly assigned to chemoradiation with or without tirapazamine: a substudy of Trans-Tasman Radiation Oncology Group Study 98.02. J Clin Oncol 2006;24:2098-104.
    • (2006) J Clin Oncol , vol.24 , pp. 2098-2104
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.