PMS1077 Sensitizes TNF-α Induced Apoptosis in Human Prostate Cancer Cells by Blocking NF-κB Signaling Pathway

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Shi, Jie ^a   Chen, Jing ^a   Serradji, Nawal ^b   Xu, Ximing ^b   Zhou, Heng ^a   Ma, Yinxing ^a   Sun, Zhihong ^a   Jiang, Peng ^b   Du, Yuping ^a   Yang, Jinbo ^a   Dong, Changzhi ^b   Wang, Qin ^a  

^a LANZHOU UNIVERSITY   (China)

^b UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; APOPTOSIS INDUCING FACTOR; I KAPPA B ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PMS 1077; PMS 1120; PMS 1141; PMS 601; PMS1141; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BINDING AFFINITY; CANCER CELL; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; DRUG STRUCTURE; GENE REPRESSION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IN VITRO STUDY; MALE; MOLECULAR DOCKING; PROSTATE CANCER; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; STRUCTURE ACTIVITY RELATION; WESTERN BLOTTING;

APOPTOSIS; CARBAMATES; CELL LINE, TUMOR; CELL NUCLEUS; ENZYME ACTIVATION; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, REPORTER; HUMANS; I-KAPPA B KINASE; MALE; MOLECULAR CONFORMATION; MOLECULAR DOCKING SIMULATION; NF-KAPPA B; PHOSPHORYLATION; PIPERAZINES; PROSTATIC NEOPLASMS; PROTEIN BINDING; PROTEIN TRANSPORT; PROTEOLYSIS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84876064300     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0061132     Document Type: Article

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