Constitutive and interleukin-1-inducible phosphorylation of p65 NF-κB at serine 536 is mediated by multiple protein kinases including IκB kinase (IKK)-α, IKKβ, IKKε, TRAF family member-associated (TANK)-binding kinase 1 (TBK1), and an unknown kinase and couples p65 to TATA-binding protein-associated factor II31-mediated interleukin-8 transcription

Journal of Biological Chemistry

Volumn 279, Issue 53, 2004, Pages 55633-55643

  Buss, Holger ^a   Dörrie, Anneke ^a   Schmitz, M Lienhard ^b   Hoffmann, Elke ^a   Resch, Klaus ^a   Kracht, Michael ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CHROMATOGRAPHIC ANALYSIS; ENZYME INHIBITION; FLUORESCENCE; FRACTIONATION; HYDROGEN BONDS; PROTEINS; RNA;

BASAL TRANSCRIPTIONAL MACHINERY; FIBROBLASTS; PHARMACOLOGICAL INHIBITORS; PHOSPHORYLATION;

ENZYMES;

BINDING PROTEIN; CYTOKINE; GREEN FLUORESCENT PROTEIN; I KAPPA B KINASE; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; I KAPPA B KINASE EPSILON; I KAPPA B KINASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE; SERINE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOTAGMIN; TATA BINDING PROTEIN ASSOCIATED FACTOR II31; TRAF FAMILY MEMBER ASSOCIATED BINDING KINASE 1; UNCLASSIFIED DRUG;

ARTICLE; CELL FRACTIONATION; CHROMATOGRAPHY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HYDROGEN BOND; INFLAMMATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FAMILY; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; TRANSACTIVATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACID SEQUENCE; BINDING SITES; BLOTTING, WESTERN; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; CHROMATOGRAPHY; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; GLUTATHIONE TRANSFERASE; GREEN FLUORESCENT PROTEINS; HELA CELLS; HUMANS; I-KAPPA B KINASE; INTERLEUKIN-1; INTERLEUKIN-8; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PLASMIDS; PROMOTER REGIONS (GENETICS); PROTEIN-SERINE-THREONINE KINASES; RNA INTERFERENCE; RNA, SMALL INTERFERING; SERINE; TATA-BINDING PROTEIN ASSOCIATED FACTORS; TIME FACTORS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTOR TFIID; TRANSFECTION;

EID: 11244285329     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M409825200     Document Type: Article

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