Alpha-tomatine induces apoptosis and inhibits nuclear factor-kappa B activation on human prostatic adenocarcinoma PC-3 cells

PLoS ONE

Volumn 6, Issue 4, 2011, Pages

  Lee, Sui Ting ^a   Wong, Pooi Fong ^a   Cheah, Shiau Chuen ^a   Mustafa, Mohd Rais ^a  

^a UNIVERSITY OF MALAYA   (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; F ACTIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PACLITAXEL; TOMATINE; TRANSCRIPTION FACTOR RELA; ALPHA-TOMATINE; CASPASE; DRUG DERIVATIVE; LIPOCORTIN 5; PROPIDIUM IODIDE; TUMOR NECROSIS FACTOR ALPHA;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CARCINOMA CELL; CELL CYCLE ARREST; CELL GROWTH; CELL MEMBRANE PERMEABILITY; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PROSTATE ADENOCARCINOMA; PROTEIN EXPRESSION; ADENOCARCINOMA; CELL CYCLE; CELL NUCLEUS; CELL SHAPE; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECT; DRUG SCREENING; ENZYMOLOGY; IMPEDANCE; KINETICS; MALE; METABOLISM; PATHOLOGY; PROSTATE TUMOR; PROTEIN TRANSPORT; TUMOR CELL LINE;

LYCOPERSICON ESCULENTUM;

ADENOCARCINOMA; ANNEXIN A5; APOPTOSIS; CASPASES; CELL CYCLE; CELL LINE, TUMOR; CELL NUCLEUS; CELL PROLIFERATION; CELL SHAPE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; ELECTRIC IMPEDANCE; ENZYME ACTIVATION; HUMANS; KINETICS; MALE; NF-KAPPA B; PROPIDIUM; PROSTATIC NEOPLASMS; PROTEIN TRANSPORT; TOMATINE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79955587641     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0018915     Document Type: Article

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