-
1
-
-
0016613531
-
Inositol phospholipids and cell surface receptor function
-
doi: 0304-4157(75)90017-9
-
R.H. Michell Inositol phospholipids and cell surface receptor function Biochim. Biophys. Acta 415 1975 81 147 doi: 0304-4157(75)90017-9
-
(1975)
Biochim. Biophys. Acta
, vol.415
, pp. 81-147
-
-
Michell, R.H.1
-
2
-
-
0021750054
-
Inositol trisphosphate, a novel second messenger in cellular signal transduction
-
M.J. Berridge, and R.F. Irvine Inositol trisphosphate, a novel second messenger in cellular signal transduction Nature 312 1984 315 321
-
(1984)
Nature
, vol.312
, pp. 315-321
-
-
Berridge, M.J.1
Irvine, R.F.2
-
3
-
-
17144395975
-
The activation of Akt/PKB signaling pathway and cell survival
-
doi: 009.001.07
-
G. Song, G. Ouyang, and S. Bao The activation of Akt/PKB signaling pathway and cell survival J. Cell. Mol. Med. 9 2005 59 71 doi: 009.001.07
-
(2005)
J. Cell. Mol. Med.
, vol.9
, pp. 59-71
-
-
Song, G.1
Ouyang, G.2
Bao, S.3
-
4
-
-
84868576048
-
Lysophospholipid receptor activation of RhoA and lipid signaling pathways
-
10.1016/j.bbalip.2012.09.004
-
S.Y. Xiang, S.S. Dusaban, and J.H. Brown Lysophospholipid receptor activation of RhoA and lipid signaling pathways Biochim. Biophys. Acta 1831 2013 213 222 10.1016/j.bbalip.2012.09.004
-
(2013)
Biochim. Biophys. Acta
, vol.1831
, pp. 213-222
-
-
Xiang, S.Y.1
Dusaban, S.S.2
Brown, J.H.3
-
5
-
-
84866254082
-
New families of bioactive oxidized phospholipids generated by immune cells: Identification and signaling actions
-
10.1182/blood-2012-04-402826
-
V.B. O'Donnell, and R.C. Murphy New families of bioactive oxidized phospholipids generated by immune cells: identification and signaling actions Blood 120 2012 1985 1992 10.1182/blood-2012-04-402826
-
(2012)
Blood
, vol.120
, pp. 1985-1992
-
-
O'Donnell, V.B.1
Murphy, R.C.2
-
6
-
-
0026909541
-
Phospholipids in the nucleus-metabolism and possible functions
-
R.F. Irvine, and N. Divecha Phospholipids in the nucleus-metabolism and possible functions Semin. Cell Biol. 3 1992 225 235
-
(1992)
Semin. Cell Biol.
, vol.3
, pp. 225-235
-
-
Irvine, R.F.1
Divecha, N.2
-
7
-
-
0037880798
-
Nuclear lipid signalling
-
10.1038/nrm1100 nrm1100
-
R.F. Irvine Nuclear lipid signalling Nat. Rev. Mol. Cell Biol. 4 2003 349 360 10.1038/nrm1100 nrm1100
-
(2003)
Nat. Rev. Mol. Cell Biol.
, vol.4
, pp. 349-360
-
-
Irvine, R.F.1
-
8
-
-
0037125879
-
Nuclear lipid signaling
-
10.1126/stke.2002.150.re13
-
R.F. Irvine Nuclear lipid signaling Sci. STKE 2002 re13 10.1126/stke.2002.150.re13
-
(2002)
Sci. STKE
, pp. 13
-
-
Irvine, R.F.1
-
9
-
-
84860721235
-
Phosphoinositides as regulators of protein-chromatin interactions
-
10.1126/scisignal.2002917
-
K. Viiri, M. Maki, and O. Lohi Phosphoinositides as regulators of protein-chromatin interactions Sci. Signal. 5 2012 pe19 10.1126/scisignal. 2002917
-
(2012)
Sci. Signal.
, vol.5
, pp. 19
-
-
Viiri, K.1
Maki, M.2
Lohi, O.3
-
10
-
-
0026513578
-
TEM cytochemical study of the localization of phospholipids in interphase chromatin in rat hepatocytes
-
A. Fraschini, E. Albi, P.B. Gahan, and M.P. Viola-Magni TEM cytochemical study of the localization of phospholipids in interphase chromatin in rat hepatocytes Histochemistry 97 1992 225 235
-
(1992)
Histochemistry
, vol.97
, pp. 225-235
-
-
Fraschini, A.1
Albi, E.2
Gahan, P.B.3
Viola-Magni, M.P.4
-
11
-
-
60549116406
-
Nuclear receptors: One big family
-
10.1007/978-1-60327-575-0-1
-
I.J. McEwan Nuclear receptors: one big family Methods Mol. Biol. 505 2009 3 18 10.1007/978-1-60327-575-0-1
-
(2009)
Methods Mol. Biol.
, vol.505
, pp. 3-18
-
-
McEwan, I.J.1
-
12
-
-
3242784885
-
Mechanism of the nuclear receptor molecular switch
-
10.1016/j.tibs.2004.04.006
-
L. Nagy, and J.W. Schwabe Mechanism of the nuclear receptor molecular switch Trends Biochem. Sci. 29 2004 317 324 10.1016/j.tibs.2004.04.006
-
(2004)
Trends Biochem. Sci.
, vol.29
, pp. 317-324
-
-
Nagy, L.1
Schwabe, J.W.2
-
13
-
-
77951901129
-
Structural overview of the nuclear receptor superfamily: Insights into physiology and therapeutics
-
10.1146/annurev-physiol-021909-135917
-
P. Huang, V. Chandra, and F. Rastinejad Structural overview of the nuclear receptor superfamily: insights into physiology and therapeutics Annu. Rev. Physiol. 72 2010 247 272 10.1146/annurev-physiol-021909-135917
-
(2010)
Annu. Rev. Physiol.
, vol.72
, pp. 247-272
-
-
Huang, P.1
Chandra, V.2
Rastinejad, F.3
-
14
-
-
79951671138
-
What are nuclear receptor ligands?
-
10.1016/j.mce.2010.06.018
-
F.M. Sladek What are nuclear receptor ligands? Mol. Cell. Endocrinol. 334 2011 3 13 10.1016/j.mce.2010.06.018
-
(2011)
Mol. Cell. Endocrinol.
, vol.334
, pp. 3-13
-
-
Sladek, F.M.1
-
15
-
-
0033617520
-
Orphan nuclear receptors: Shifting endocrinology into reverse
-
S.A. Kliewer, J.M. Lehmann, and T.M. Willson Orphan nuclear receptors: shifting endocrinology into reverse Science 284 1999 757 760
-
(1999)
Science
, vol.284
, pp. 757-760
-
-
Kliewer, S.A.1
Lehmann, J.M.2
Willson, T.M.3
-
16
-
-
2642551635
-
The flip side: Identifying small molecule regulators of nuclear receptors
-
10.1016/j.chembiol.2003.12.021
-
I.G. Schulman, and R.A. Heyman The flip side: identifying small molecule regulators of nuclear receptors Chem. Biol. 11 2004 639 646 10.1016/j.chembiol. 2003.12.021
-
(2004)
Chem. Biol.
, vol.11
, pp. 639-646
-
-
Schulman, I.G.1
Heyman, R.A.2
-
17
-
-
33646772536
-
The nuclear receptor superfamily and drug discovery
-
10.1002/cmdc.200600006
-
J.T. Moore, J.L. Collins, and K.H. Pearce The nuclear receptor superfamily and drug discovery ChemMedChem 1 2006 504 523 10.1002/cmdc.200600006
-
(2006)
ChemMedChem
, vol.1
, pp. 504-523
-
-
Moore, J.T.1
Collins, J.L.2
Pearce, K.H.3
-
18
-
-
79958265623
-
Emerging actions of the nuclear receptor LRH-1 in the gut
-
10.1016/j.bbadis.2010.12.010
-
P.J. Fernandez-Marcos, J. Auwerx, and K. Schoonjans Emerging actions of the nuclear receptor LRH-1 in the gut Biochim. Biophys. Acta 1812 2011 947 955 10.1016/j.bbadis.2010.12.010
-
(2011)
Biochim. Biophys. Acta
, vol.1812
, pp. 947-955
-
-
Fernandez-Marcos, P.J.1
Auwerx, J.2
Schoonjans, K.3
-
19
-
-
52049108214
-
Liver receptor homolog-1, an emerging metabolic modulator
-
Y.-k. Lee, and D.D. Moore Liver receptor homolog-1, an emerging metabolic modulator Front. Biosci. 13 2008 5950 5958
-
(2008)
Front. Biosci.
, vol.13
, pp. 5950-5958
-
-
Lee, Y.-K.1
Moore, D.D.2
-
20
-
-
77749299137
-
Transcriptional regulation of the Oct4 gene, a master gene for pluripotency
-
S. Kellner, and N. Kikyo Transcriptional regulation of the Oct4 gene, a master gene for pluripotency Histol. Histopathol. 25 2010 405 412
-
(2010)
Histol. Histopathol.
, vol.25
, pp. 405-412
-
-
Kellner, S.1
Kikyo, N.2
-
21
-
-
4344629704
-
Synergy between LRH-1 and beta-catenin induces G1 cyclin-mediated cell proliferation
-
10.1016/j.molcel.2004.07.009
-
Oa Botrugno, E. Fayard, J.-S. Annicotte, C. Haby, T. Brennan, O. Wendling, T. Tanaka, T. Kodama, W. Thomas, and J. Auwerx Synergy between LRH-1 and beta-catenin induces G1 cyclin-mediated cell proliferation Mol. Cell 15 2004 499 509 10.1016/j.molcel.2004.07.009
-
(2004)
Mol. Cell
, vol.15
, pp. 499-509
-
-
Botrugno, O.1
Fayard, E.2
Annicotte, J.-S.3
Haby, C.4
Brennan, T.5
Wendling, O.6
Tanaka, T.7
Kodama, T.8
Thomas, W.9
Auwerx, J.10
-
22
-
-
75349088911
-
The nuclear receptor Nr5a2 can replace Oct4 in the reprogramming of murine somatic cells to pluripotent cells
-
10.1016/j.stem.2009.12.009
-
J.C. Heng, B. Feng, J. Han, J. Jiang, P. Kraus, J.H. Ng, Y.L. Orlov, M. Huss, L. Yang, and T. Lufkin The nuclear receptor Nr5a2 can replace Oct4 in the reprogramming of murine somatic cells to pluripotent cells Cell Stem Cell 6 2010 167 174 10.1016/j.stem.2009.12.009
-
(2010)
Cell Stem Cell
, vol.6
, pp. 167-174
-
-
Heng, J.C.1
Feng, B.2
Han, J.3
Jiang, J.4
Kraus, P.5
Ng, J.H.6
Orlov, Y.L.7
Huss, M.8
Yang, L.9
Lufkin, T.10
-
23
-
-
84867847977
-
Regulation of OCT4 gene expression by liver receptor homolog-1 in human embryonic carcinoma cells
-
10.1016/j.bbrc.2012.09.049
-
B. Sung, H.J. Do, S.W. Park, S.H. Huh, J.H. Oh, H.J. Chung, M.J. Kang, J.H. Kim, and N.H. Kim Regulation of OCT4 gene expression by liver receptor homolog-1 in human embryonic carcinoma cells Biochem. Biophys. Res. Commun. 2012 10.1016/j.bbrc.2012.09.049
-
(2012)
Biochem. Biophys. Res. Commun.
-
-
Sung, B.1
Do, H.J.2
Park, S.W.3
Huh, S.H.4
Oh, J.H.5
Chung, H.J.6
Kang, M.J.7
Kim, J.H.8
Kim, N.H.9
-
24
-
-
0037036456
-
Liver receptor homologue-1 (LRH-1) regulates expression of aromatase in preadipocytes
-
10.1074/jbc.M201117200
-
C.D. Clyne, C.J. Speed, J. Zhou, and E.R. Simpson Liver receptor homologue-1 (LRH-1) regulates expression of aromatase in preadipocytes J. Biol. Chem. 277 2002 20591 20597 10.1074/jbc.M201117200
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 20591-20597
-
-
Clyne, C.D.1
Speed, C.J.2
Zhou, J.3
Simpson, E.R.4
-
25
-
-
0033637121
-
A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis
-
B. Goodwin, Sa Jones, R.R. Price, Ma Watson, D.D. McKee, L.B. Moore, C. Galardi, J.G. Wilson, M.C. Lewis, and M.E. Roth A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis Mol. Cell 6 2000 517 526
-
(2000)
Mol. Cell
, vol.6
, pp. 517-526
-
-
Goodwin, B.1
Jones, S.2
Price, R.R.3
Watson, M.4
McKee, D.D.5
Moore, L.B.6
Galardi, C.7
Wilson, J.G.8
Lewis, M.C.9
Roth, M.E.10
-
26
-
-
0037827787
-
Liver receptor homologue-1 mediates species- and cell line-specific bile acid-dependent negative feedback regulation of the apical sodium-dependent bile acid transporter
-
F. Chen, L. Ma, P.A. Dawson, C.J. Sinal, E. Sehayek, F.J. Gonzalez, J. Breslow, M. Ananthanarayanan, and B.L. Shneider Liver receptor homologue-1 mediates species- and cell line-specific bile acid-dependent negative feedback regulation of the apical sodium-dependent bile acid transporter J. Biol. Chem. 278 2003 19909 19916
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 19909-19916
-
-
Chen, F.1
Ma, L.2
Dawson, P.A.3
Sinal, C.J.4
Sehayek, E.5
Gonzalez, F.J.6
Breslow, J.7
Ananthanarayanan, M.8
Shneider, B.L.9
-
27
-
-
0034666027
-
Role of FXR and FTF in bile acid-mediated suppression of cholesterol 7alpha-hydroxylase transcription
-
A. del Castillo-Olivares, and G. Gil Role of FXR and FTF in bile acid-mediated suppression of cholesterol 7alpha-hydroxylase transcription Nucleic Acids Res. 28 2000 3587 3593
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 3587-3593
-
-
Del Castillo-Olivares, A.1
Gil, G.2
-
28
-
-
5044229657
-
Identification of liver receptor homolog-1 as a novel regulator of apolipoprotein AI gene transcription
-
P. Delerive, C.M. Galardi, J.E. Bisi, E. Nicodeme, and B. Goodwin Identification of liver receptor homolog-1 as a novel regulator of apolipoprotein AI gene transcription Mol. Endocrinol. 18 2004 2378 2387
-
(2004)
Mol. Endocrinol.
, vol.18
, pp. 2378-2387
-
-
Delerive, P.1
Galardi, C.M.2
Bisi, J.E.3
Nicodeme, E.4
Goodwin, B.5
-
29
-
-
3042520972
-
The orphan nuclear receptor LRH-1 activates the ABCG5/ABCG8 intergenic promoter
-
L.A. Freeman, A. Kennedy, J. Wu, S. Bark, A.T. Remaley, S. Santamarina-Fojo, and H.B. Brewer Jr. The orphan nuclear receptor LRH-1 activates the ABCG5/ABCG8 intergenic promoter J. Lipid Res. 45 2004 1197 1206
-
(2004)
J. Lipid Res.
, vol.45
, pp. 1197-1206
-
-
Freeman, L.A.1
Kennedy, A.2
Wu, J.3
Bark, S.4
Remaley, A.T.5
Santamarina-Fojo, S.6
Brewer, Jr.H.B.7
-
30
-
-
0035861581
-
Enhanced expression of the human multidrug resistance protein 3 by bile salt in human enterocytes. A transcriptional control of a plausible bile acid transporter
-
10.1074/jbc.M104612200
-
A. Inokuchi, E. Hinoshita, Y. Iwamoto, K. Kohno, M. Kuwano, and T. Uchiumi Enhanced expression of the human multidrug resistance protein 3 by bile salt in human enterocytes. A transcriptional control of a plausible bile acid transporter J. Biol. Chem. 276 2001 46822 46829 10.1074/jbc.M104612200
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 46822-46829
-
-
Inokuchi, A.1
Hinoshita, E.2
Iwamoto, Y.3
Kohno, K.4
Kuwano, M.5
Uchiumi, T.6
-
31
-
-
44649202231
-
Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis
-
10.1210/me.2007-0565
-
Y.K. Lee, D.R. Schmidt, C.L. Cummins, M. Choi, L. Peng, Y. Zhang, B. Goodwin, R.E. Hammer, D.J. Mangelsdorf, and S.A. Kliewer Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis Mol. Endocrinol. 22 2008 1345 1356 10.1210/me.2007-0565
-
(2008)
Mol. Endocrinol.
, vol.22
, pp. 1345-1356
-
-
Lee, Y.K.1
Schmidt, D.R.2
Cummins, C.L.3
Choi, M.4
Peng, L.5
Zhang, Y.6
Goodwin, B.7
Hammer, R.E.8
Mangelsdorf, D.J.9
Kliewer, S.A.10
-
32
-
-
0035816609
-
The orphan nuclear receptor LRH-1 potentiates the sterol-mediated induction of the human CETP gene by liver X receptor
-
Y. Luo, C.P. Liang, and A.R. Tall The orphan nuclear receptor LRH-1 potentiates the sterol-mediated induction of the human CETP gene by liver X receptor J. Biol. Chem. 276 2001 24767 24773
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 24767-24773
-
-
Luo, Y.1
Liang, C.P.2
Tall, A.R.3
-
33
-
-
84864752368
-
LRH-1-dependent glucose sensing determines intermediary metabolism in liver
-
10.1172/JCI6236862368
-
M.H. Oosterveer, C. Mataki, H. Yamamoto, T. Harach, N. Moullan, T.H. van Dijk, E. Ayuso, F. Bosch, C. Postic, and A.K. Groen LRH-1-dependent glucose sensing determines intermediary metabolism in liver J. Clin. Invest. 122 2012 2817 2826 10.1172/JCI6236862368
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 2817-2826
-
-
Oosterveer, M.H.1
Mataki, C.2
Yamamoto, H.3
Harach, T.4
Moullan, N.5
Van Dijk, T.H.6
Ayuso, E.7
Bosch, F.8
Postic, C.9
Groen, A.K.10
-
34
-
-
26844486254
-
Protein kinase A-dependent synergism between GATA factors and the nuclear receptor, liver receptor homolog-1, regulates human aromatase (CYP19) PII promoter activity in breast cancer cells
-
10.1210/en.2005-0187
-
M.F. Bouchard, H. Taniguchi, and R.S. Viger Protein kinase A-dependent synergism between GATA factors and the nuclear receptor, liver receptor homolog-1, regulates human aromatase (CYP19) PII promoter activity in breast cancer cells Endocrinology 146 2005 4905 4916 10.1210/en.2005-0187
-
(2005)
Endocrinology
, vol.146
, pp. 4905-4916
-
-
Bouchard, M.F.1
Taniguchi, H.2
Viger, R.S.3
-
35
-
-
28744459007
-
The nuclear receptor liver receptor homolog-1 is an estrogen receptor target gene
-
10.1038/sj.onc.1208950
-
J.-S. Annicotte, C. Chavey, N. Servant, J. Teyssier, A. Bardin, A. Licznar, E. Badia, P. Pujol, F. Vignon, and T. Maudelonde The nuclear receptor liver receptor homolog-1 is an estrogen receptor target gene Oncogene 24 2005 8167 8175 10.1038/sj.onc.1208950
-
(2005)
Oncogene
, vol.24
, pp. 8167-8175
-
-
Annicotte, J.-S.1
Chavey, C.2
Servant, N.3
Teyssier, J.4
Bardin, A.5
Licznar, A.6
Badia, E.7
Pujol, P.8
Vignon, F.9
Maudelonde, T.10
-
36
-
-
38649119427
-
Increased expression of hLRH-1 in human gastric cancer and its implication in tumorigenesis
-
10.1007/s11010-007-9616-1
-
S.-L. Wang, D.-Z. Zheng, F.-H. Lan, X.-J. Deng, J. Zeng, C.-J. Li, R. Wang, and Z.-Y. Zhu Increased expression of hLRH-1 in human gastric cancer and its implication in tumorigenesis Mol. Cell. Biochem. 308 2008 93 100 10.1007/s11010-007-9616-1
-
(2008)
Mol. Cell. Biochem.
, vol.308
, pp. 93-100
-
-
Wang, S.-L.1
Zheng, D.-Z.2
Lan, F.-H.3
Deng, X.-J.4
Zeng, J.5
Li, C.-J.6
Wang, R.7
Zhu, Z.-Y.8
-
37
-
-
0038503976
-
Structural basis for ligand-independent activation of the orphan nuclear receptor LRH-1
-
E.P. Sablin, I.N. Krylova, R.J. Fletterick, and H.A. Ingraham Structural basis for ligand-independent activation of the orphan nuclear receptor LRH-1 Mol. Cell 11 2003 1575 1585
-
(2003)
Mol. Cell
, vol.11
, pp. 1575-1585
-
-
Sablin, E.P.1
Krylova, I.N.2
Fletterick, R.J.3
Ingraham, H.A.4
-
38
-
-
21144448184
-
The crystal structures of human steroidogenic factor-1 and liver receptor homologue-1
-
W. Wang, C. Zhang, A. Marimuthu, H.I. Krupka, M. Tabrizizad, R. Shelloe, U. Mehra, K. Eng, H. Nguyen, and C. Settachatgul The crystal structures of human steroidogenic factor-1 and liver receptor homologue-1 Proc. Natl. Acad. Sci. U.S.A. 102 2005 7505 7510
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 7505-7510
-
-
Wang, W.1
Zhang, C.2
Marimuthu, A.3
Krupka, H.I.4
Tabrizizad, M.5
Shelloe, R.6
Mehra, U.7
Eng, K.8
Nguyen, H.9
Settachatgul, C.10
-
39
-
-
20844456958
-
Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP
-
10.1038/nsmb910
-
E.A. Ortlund, Y. Lee, I.H. Solomon, J.M. Hager, R. Safi, Y. Choi, Z. Guan, A. Tripathy, C.R.H. Raetz, and D.P. McDonnell Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP Nat. Struct. Mol. Biol. 12 2005 357 363 10.1038/nsmb910
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 357-363
-
-
Ortlund, E.A.1
Lee, Y.2
Solomon, I.H.3
Hager, J.M.4
Safi, R.5
Choi, Y.6
Guan, Z.7
Tripathy, A.8
Raetz, C.R.H.9
McDonnell, D.P.10
-
40
-
-
13544263313
-
Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1
-
10.1016/j.cell.2005.01.024
-
I.N. Krylova, E.P. Sablin, J. Moore, R.X. Xu, G.M. Waitt, J.A. MacKay, D. Juzumiene, J.M. Bynum, K. Madauss, and V. Montana Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1 Cell 120 2005 343 355 10.1016/j.cell.2005.01.024
-
(2005)
Cell
, vol.120
, pp. 343-355
-
-
Krylova, I.N.1
Sablin, E.P.2
Moore, J.3
Xu, R.X.4
Waitt, G.M.5
MacKay, J.A.6
Juzumiene, D.7
Bynum, J.M.8
Madauss, K.9
Montana, V.10
-
41
-
-
84860733689
-
Antidiabetic phospholipid-nuclear receptor complex reveals the mechanism for phospholipid-driven gene regulation
-
532537 10.1038/nsmb.2279
-
P.M. Musille, M.C. Pathak, J.L. Lauer, W.H. Hudson, P.R. Griffin, and E.A. Ortlund Antidiabetic phospholipid-nuclear receptor complex reveals the mechanism for phospholipid-driven gene regulation Nat. Struct. Mol. Biol. 19 532-537 2012 S531 S532 10.1038/nsmb.2279
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
-
-
Musille, P.M.1
Pathak, M.C.2
Lauer, J.L.3
Hudson, W.H.4
Griffin, P.R.5
Ortlund, E.A.6
-
42
-
-
79959560633
-
A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects
-
10.1038/nature10111
-
J.M. Lee, Y.K. Lee, J.L. Mamrosh, Sa Busby, P.R. Griffin, M.C. Pathak, Ea Ortlund, and D.D. Moore A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects Nature 2011 10.1038/nature10111
-
(2011)
Nature
-
-
Lee, J.M.1
Lee, Y.K.2
Mamrosh, J.L.3
Busby, S.4
Griffin, P.R.5
Pathak, M.C.6
Ortlund, E.7
Moore, D.D.8
-
43
-
-
84876047289
-
Targeting nuclear receptors to treat type 2 diabetes
-
Kyoto, Japan
-
Moore, D. (2010) Targeting nuclear receptors to treat type 2 diabetes. In 14th International Congress of Endocrinology, Kyoto, Japan.
-
(2010)
14th International Congress of Endocrinology
-
-
Moore, D.1
-
44
-
-
71949093664
-
Molecular aspects of steroidogenic factor 1 (SF-1)
-
10.1016/j.mce.2009.07.003
-
E.A. Hoivik, A.E. Lewis, L. Aumo, and M. Bakke Molecular aspects of steroidogenic factor 1 (SF-1) Mol. Cell. Endocrinol. 315 2010 27 39 10.1016/j.mce.2009.07.003
-
(2010)
Mol. Cell. Endocrinol.
, vol.315
, pp. 27-39
-
-
Hoivik, E.A.1
Lewis, A.E.2
Aumo, L.3
Bakke, M.4
-
45
-
-
0029123832
-
Developmental defects of the ventromedial hypothalamic nucleus and pituitary gonadotroph in the Ftz-F1 disrupted mice
-
10.1002/aja.1002040104
-
K. Shinoda, H. Lei, H. Yoshii, M. Nomura, M. Nagano, H. Shiba, H. Sasaki, Y. Osawa, Y. Ninomiya, and O. Niwa Developmental defects of the ventromedial hypothalamic nucleus and pituitary gonadotroph in the Ftz-F1 disrupted mice Dev. Dyn. 204 1995 22 29 10.1002/aja.1002040104
-
(1995)
Dev. Dyn.
, vol.204
, pp. 22-29
-
-
Shinoda, K.1
Lei, H.2
Yoshii, H.3
Nomura, M.4
Nagano, M.5
Shiba, H.6
Sasaki, H.7
Osawa, Y.8
Ninomiya, Y.9
Niwa, O.10
-
46
-
-
0027971944
-
The nuclear receptor steroidogenic factor 1 acts at multiple levels of the reproductive axis
-
H.A. Ingraham, D.S. Lala, Y. Ikeda, X. Luo, W.H. Shen, M.W. Nachtigal, R. Abbud, J.H. Nilson, and K.L. Parker The nuclear receptor steroidogenic factor 1 acts at multiple levels of the reproductive axis Genes Dev. 8 1994 2302 2312
-
(1994)
Genes Dev.
, vol.8
, pp. 2302-2312
-
-
Ingraham, H.A.1
Lala, D.S.2
Ikeda, Y.3
Luo, X.4
Shen, W.H.5
Nachtigal, M.W.6
Abbud, R.7
Nilson, J.H.8
Parker, K.L.9
-
47
-
-
0034664937
-
Contribution of steroidogenic factor 1 to the regulation of cholesterol synthesis
-
C. Mascaro, A. Nadal, F.G. Hegardt, P.F. Marrero, and D. Haro Contribution of steroidogenic factor 1 to the regulation of cholesterol synthesis Biochem. J. 350 Pt 3 2000 785 790
-
(2000)
Biochem. J.
, vol.350
, Issue.PART 3
, pp. 785-790
-
-
Mascaro, C.1
Nadal, A.2
Hegardt, F.G.3
Marrero, P.F.4
Haro, D.5
-
48
-
-
0030014414
-
Steroidogenic factor 1-dependent promoter activity of the human steroidogenic acute regulatory protein (StAR) gene
-
10.1021/bi960057r
-
T. Sugawara, J.A. Holt, M. Kiriakidou, and J.F. Strauss 3rd Steroidogenic factor 1-dependent promoter activity of the human steroidogenic acute regulatory protein (StAR) gene Biochemistry 35 1996 9052 9059 10.1021/bi960057r
-
(1996)
Biochemistry
, vol.35
, pp. 9052-9059
-
-
Sugawara, T.1
Holt, J.A.2
Kiriakidou, M.3
Strauss III, J.F.4
-
49
-
-
0031453246
-
Structure and localization of the human gene encoding SR-BI/CLA-1. Evidence for transcriptional control by steroidogenic factor 1
-
G. Cao, C.K. Garcia, K.L. Wyne, R.A. Schultz, K.L. Parker, and H.H. Hobbs Structure and localization of the human gene encoding SR-BI/CLA-1. Evidence for transcriptional control by steroidogenic factor 1 J. Biol. Chem. 272 1997 33068 33076
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 33068-33076
-
-
Cao, G.1
Garcia, C.K.2
Wyne, K.L.3
Schultz, R.A.4
Parker, K.L.5
Hobbs, H.H.6
-
50
-
-
0035022417
-
Characterization of a steroidogenic factor-1-binding site found in promoter of sterol carrier protein-2 gene
-
10.1385/ENDO:14:2:253
-
D. Lopez, W. Shea-Eaton, and M.P. McLean Characterization of a steroidogenic factor-1-binding site found in promoter of sterol carrier protein-2 gene Endocrine 14 2001 253 261 10.1385/ENDO:14:2:253
-
(2001)
Endocrine
, vol.14
, pp. 253-261
-
-
Lopez, D.1
Shea-Eaton, W.2
McLean, M.P.3
-
51
-
-
0031010818
-
Steroidogenic factor 1: A key determinant of endocrine development and function
-
K.L. Parker, and B.P. Schimmer Steroidogenic factor 1: a key determinant of endocrine development and function Endocr. Rev. 18 1997 361 377
-
(1997)
Endocr. Rev.
, vol.18
, pp. 361-377
-
-
Parker, K.L.1
Schimmer, B.P.2
-
52
-
-
77954832944
-
Minireview: Steroidogenic factor 1: Its roles in differentiation, development, and disease
-
10.1210/me.2009-0519
-
B.P. Schimmer, and P.C. White Minireview: steroidogenic factor 1: its roles in differentiation, development, and disease Mol. Endocrinol. 24 2010 1322 1337 10.1210/me.2009-0519
-
(2010)
Mol. Endocrinol.
, vol.24
, pp. 1322-1337
-
-
Schimmer, B.P.1
White, P.C.2
-
53
-
-
79952070611
-
Steroidogenic factor-1 (SF-1, NR5A1) and human disease
-
10.1016/j.mce.2010.11.006
-
B. Ferraz-de-Souza, L. Lin, and J.C. Achermann Steroidogenic factor-1 (SF-1, NR5A1) and human disease Mol. Cell. Endocrinol. 336 2011 198 205 10.1016/j.mce.2010.11.006
-
(2011)
Mol. Cell. Endocrinol.
, vol.336
, pp. 198-205
-
-
Ferraz-De-Souza, B.1
Lin, L.2
Achermann, J.C.3
-
54
-
-
1942505197
-
A microdeletion in the ligand binding domain of human steroidogenic factor 1 causes XY sex reversal without adrenal insufficiency
-
R.V. Correa, S. Domenice, N.C. Bingham, A.E. Billerbeck, W.E. Rainey, K.L. Parker, and B.B. Mendonca A microdeletion in the ligand binding domain of human steroidogenic factor 1 causes XY sex reversal without adrenal insufficiency J. Clin. Endocrinol. Metab. 89 2004 1767 1772
-
(2004)
J. Clin. Endocrinol. Metab.
, vol.89
, pp. 1767-1772
-
-
Correa, R.V.1
Domenice, S.2
Bingham, N.C.3
Billerbeck, A.E.4
Rainey, W.E.5
Parker, K.L.6
Mendonca, B.B.7
-
55
-
-
84863571720
-
Ten novel mutations in the NR5A1 gene cause disordered sex development in 46, XY and ovarian insufficiency in 46, XX individuals
-
10.1210/jc.2011-3169
-
N. Camats, A.V. Pandey, M. Fernandez-Cancio, P. Andaluz, M. Janner, N. Toran, F. Moreno, A. Bereket, T. Akcay, and E. Garcia-Garcia Ten novel mutations in the NR5A1 gene cause disordered sex development in 46, XY and ovarian insufficiency in 46, XX individuals J. Clin. Endocrinol. Metab. 97 2012 E1294 E1306 10.1210/jc.2011-3169
-
(2012)
J. Clin. Endocrinol. Metab.
, vol.97
-
-
Camats, N.1
Pandey, A.V.2
Fernandez-Cancio, M.3
Andaluz, P.4
Janner, M.5
Toran, N.6
Moreno, F.7
Bereket, A.8
Akcay, T.9
Garcia-Garcia, E.10
-
56
-
-
0032990419
-
A mutation in the gene encoding steroidogenic factor-1 causes XY sex reversal and adrenal failure in humans
-
10.1038/9629
-
J.C. Achermann, M. Ito, P.C. Hindmarsh, and J.L. Jameson A mutation in the gene encoding steroidogenic factor-1 causes XY sex reversal and adrenal failure in humans Nat. Genet. 22 1999 125 126 10.1038/9629
-
(1999)
Nat. Genet.
, vol.22
, pp. 125-126
-
-
Achermann, J.C.1
Ito, M.2
Hindmarsh, P.C.3
Jameson, J.L.4
-
57
-
-
55749088979
-
Steroidogenic factor-1 (SF-1, Ad4BP, NR5A1) and disorders of testis development
-
10.1159/000152036
-
L. Lin, and J.C. Achermann Steroidogenic factor-1 (SF-1, Ad4BP, NR5A1) and disorders of testis development Sex Dev. 2 2008 200 209 10.1159/000152036
-
(2008)
Sex Dev.
, vol.2
, pp. 200-209
-
-
Lin, L.1
Achermann, J.C.2
-
58
-
-
59649084599
-
Steroidogenic factor-1 and endometriosis
-
10.1016/j.mce.2008.12.012
-
S.E. Bulun, H. Utsunomiya, Z. Lin, P. Yin, Y.H. Cheng, M.E. Pavone, H. Tokunaga, E. Trukhacheva, E. Attar, and B. Gurates Steroidogenic factor-1 and endometriosis Mol. Cell. Endocrinol. 300 2009 104 108 10.1016/j.mce.2008.12.012
-
(2009)
Mol. Cell. Endocrinol.
, vol.300
, pp. 104-108
-
-
Bulun, S.E.1
Utsunomiya, H.2
Lin, Z.3
Yin, P.4
Cheng, Y.H.5
Pavone, M.E.6
Tokunaga, H.7
Trukhacheva, E.8
Attar, E.9
Gurates, B.10
-
59
-
-
33646521924
-
SF-1 overexpression in childhood adrenocortical tumours
-
10.1016/j.ejca.2006.01.022
-
M.A. Pianovski, L.R. Cavalli, B.C. Figueiredo, S.C. Santos, M. Doghman, R.C. Ribeiro, A.G. Oliveira, E. Michalkiewicz, G.A. Rodrigues, and G. Zambetti SF-1 overexpression in childhood adrenocortical tumours Eur. J. Cancer 42 2006 1040 1043 10.1016/j.ejca.2006.01.022
-
(2006)
Eur. J. Cancer
, vol.42
, pp. 1040-1043
-
-
Pianovski, M.A.1
Cavalli, L.R.2
Figueiredo, B.C.3
Santos, S.C.4
Doghman, M.5
Ribeiro, R.C.6
Oliveira, A.G.7
Michalkiewicz, E.8
Rodrigues, G.A.9
Zambetti, G.10
-
60
-
-
40849111661
-
Identification of the first synthetic steroidogenic factor 1 inverse agonists: Pharmacological modulation of steroidogenic enzymes
-
10.1124/mol.107.040089
-
A.L. Del Tredici, C.B. Andersen, E.A. Currier, S.R. Ohrmund, L.C. Fairbain, B.W. Lund, N. Nash, R. Olsson, and F. Piu Identification of the first synthetic steroidogenic factor 1 inverse agonists: pharmacological modulation of steroidogenic enzymes Mol. Pharmacol. 73 2008 900 908 10.1124/mol.107.040089
-
(2008)
Mol. Pharmacol.
, vol.73
, pp. 900-908
-
-
Del Tredici, A.L.1
Andersen, C.B.2
Currier, E.A.3
Ohrmund, S.R.4
Fairbain, L.C.5
Lund, B.W.6
Nash, N.7
Olsson, R.8
Piu, F.9
-
61
-
-
44249089742
-
Potent, selective and cell penetrant inhibitors of SF-1 by functional ultra-high-throughput screening
-
10.1124/mol.108.045963
-
F. Madoux, X. Li, P. Chase, G. Zastrow, M.D. Cameron, J.J. Conkright, P.R. Griffin, S. Thacher, and P. Hodder Potent, selective and cell penetrant inhibitors of SF-1 by functional ultra-high-throughput screening Mol. Pharmacol. 73 2008 1776 1784 10.1124/mol.108.045963
-
(2008)
Mol. Pharmacol.
, vol.73
, pp. 1776-1784
-
-
Madoux, F.1
Li, X.2
Chase, P.3
Zastrow, G.4
Cameron, M.D.5
Conkright, J.J.6
Griffin, P.R.7
Thacher, S.8
Hodder, P.9
-
62
-
-
41949130346
-
Synthesis of small molecule inhibitors of the orphan nuclear receptor steroidogenic factor-1 (NR5A1) based on isoquinolinone scaffolds
-
10.1016/j.bmcl.2008.03.027
-
J. Roth, F. Madoux, P. Hodder, and W.R. Roush Synthesis of small molecule inhibitors of the orphan nuclear receptor steroidogenic factor-1 (NR5A1) based on isoquinolinone scaffolds Bioorg. Med. Chem. Lett. 18 2008 2628 2632 10.1016/j.bmcl.2008.03.027
-
(2008)
Bioorg. Med. Chem. Lett.
, vol.18
, pp. 2628-2632
-
-
Roth, J.1
Madoux, F.2
Hodder, P.3
Roush, W.R.4
-
63
-
-
66749179396
-
Inhibition of adrenocortical carcinoma cell proliferation by steroidogenic factor-1 inverse agonists
-
10.1210/jc.2008-2163
-
M. Doghman, J. Cazareth, D. Douguet, F. Madoux, P. Hodder, and E. Lalli Inhibition of adrenocortical carcinoma cell proliferation by steroidogenic factor-1 inverse agonists J. Clin. Endocrinol. Metab. 94 2009 2178 2183 10.1210/jc.2008-2163
-
(2009)
J. Clin. Endocrinol. Metab.
, vol.94
, pp. 2178-2183
-
-
Doghman, M.1
Cazareth, J.2
Douguet, D.3
Madoux, F.4
Hodder, P.5
Lalli, E.6
-
64
-
-
13944276441
-
Crystallographic identification and functional characterization of phospholipids as ligands for the orphan nuclear receptor steroidogenic factor-1
-
Y. Li, M. Choi, G. Cavey, J. Daugherty, K. Suino, A. Kovach, N.C. Bingham, S.A. Kliewer, and H.E. Xu Crystallographic identification and functional characterization of phospholipids as ligands for the orphan nuclear receptor steroidogenic factor-1 Mol. Cell 17 2005 491 502
-
(2005)
Mol. Cell
, vol.17
, pp. 491-502
-
-
Li, Y.1
Choi, M.2
Cavey, G.3
Daugherty, J.4
Suino, K.5
Kovach, A.6
Bingham, N.C.7
Kliewer, S.A.8
Xu, H.E.9
-
65
-
-
33751250805
-
Sphingosine regulates the transcription of CYP17 by binding to steroidogenic factor-1
-
10.1210/en.2006-0355
-
A.N. Urs, E. Dammer, and M.B. Sewer Sphingosine regulates the transcription of CYP17 by binding to steroidogenic factor-1 Endocrinology 147 2006 5249 5258 10.1210/en.2006-0355
-
(2006)
Endocrinology
, vol.147
, pp. 5249-5258
-
-
Urs, A.N.1
Dammer, E.2
Sewer, M.B.3
-
66
-
-
34748826098
-
Cyclic AMP-stimulated interaction between steroidogenic factor 1 and diacylglycerol kinase theta facilitates induction of CYP17
-
10.1128/MCB.00355-07
-
D. Li, A.N. Urs, J. Allegood, A. Leon, A.H. Merrill Jr.; and M.B. Sewer Cyclic AMP-stimulated interaction between steroidogenic factor 1 and diacylglycerol kinase theta facilitates induction of CYP17 Mol. Cell. Biol. 27 2007 6669 6685 10.1128/MCB.00355-07
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 6669-6685
-
-
Li, D.1
Urs, A.N.2
Allegood, J.3
Leon, A.4
Merrill, Jr.A.H.5
Sewer, M.B.6
-
67
-
-
33847011721
-
Steroidogenic factor-1 is a sphingolipid binding protein
-
10.1016/j.mce.2006.12.016
-
A.N. Urs, E. Dammer, S. Kelly, E. Wang, A.H. Merrill Jr.; and M.B. Sewer Steroidogenic factor-1 is a sphingolipid binding protein Mol. Cell. Endocrinol. 265-266 2007 174 178 10.1016/j.mce.2006.12.016
-
(2007)
Mol. Cell. Endocrinol.
, vol.265-266
, pp. 174-178
-
-
Urs, A.N.1
Dammer, E.2
Kelly, S.3
Wang, E.4
Merrill, Jr.A.H.5
Sewer, M.B.6
-
68
-
-
58149242786
-
Structure of SF-1 bound by different phospholipids: Evidence for regulatory ligands
-
10.1210/me.2007-0508
-
E.P. Sablin, R.D. Blind, I.N. Krylova, J.G. Ingraham, F. Cai, J.D. Williams, R.J. Fletterick, and H.A. Ingraham Structure of SF-1 bound by different phospholipids: evidence for regulatory ligands Mol. Endocrinol. 23 2009 25 34 10.1210/me.2007-0508
-
(2009)
Mol. Endocrinol.
, vol.23
, pp. 25-34
-
-
Sablin, E.P.1
Blind, R.D.2
Krylova, I.N.3
Ingraham, J.G.4
Cai, F.5
Williams, J.D.6
Fletterick, R.J.7
Ingraham, H.A.8
-
69
-
-
84862884630
-
Direct modification and activation of a nuclear receptor-PIP(2) complex by the inositol lipid kinase IPMK
-
10.1126/scisignal.2003111
-
R.D. Blind, M. Suzawa, and H.A. Ingraham Direct modification and activation of a nuclear receptor-PIP(2) complex by the inositol lipid kinase IPMK Sci. Signal. 5 2012 ra44 10.1126/scisignal.2003111
-
(2012)
Sci. Signal.
, vol.5
, pp. 44
-
-
Blind, R.D.1
Suzawa, M.2
Ingraham, H.A.3
-
70
-
-
47949094965
-
Integration of metabolism and inflammation by lipid-activated nuclear receptors
-
10.1038/nature07202
-
S.J. Bensinger, and P. Tontonoz Integration of metabolism and inflammation by lipid-activated nuclear receptors Nature 454 2008 470 477 10.1038/nature07202
-
(2008)
Nature
, vol.454
, pp. 470-477
-
-
Bensinger, S.J.1
Tontonoz, P.2
-
71
-
-
0033305213
-
Peroxisome proliferator-activated receptors: Nuclear control of metabolism
-
B. Desvergne, and W. Wahli Peroxisome proliferator-activated receptors: nuclear control of metabolism Endocr. Rev. 20 1999 649 688
-
(1999)
Endocr. Rev.
, vol.20
, pp. 649-688
-
-
Desvergne, B.1
Wahli, W.2
-
72
-
-
0036183630
-
The mechanisms of action of PPARs
-
10.1146/annurev.med.53.082901.104018
-
J. Berger, and D.E. Moller The mechanisms of action of PPARs Annu. Rev. Med. 53 2002 409 435 10.1146/annurev.med.53.082901.104018
-
(2002)
Annu. Rev. Med.
, vol.53
, pp. 409-435
-
-
Berger, J.1
Moller, D.E.2
-
73
-
-
0027993220
-
The peroxisome proliferator-activated receptor interacts with the retinoid X receptor in vivo
-
K.S. Miyata, S.E. McCaw, S.L. Marcus, R.A. Rachubinski, and J.P. Capone The peroxisome proliferator-activated receptor interacts with the retinoid X receptor in vivo Gene 148 1994 327 330
-
(1994)
Gene
, vol.148
, pp. 327-330
-
-
Miyata, K.S.1
McCaw, S.E.2
Marcus, S.L.3
Rachubinski, R.A.4
Capone, J.P.5
-
74
-
-
0030747895
-
Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: No alteration in adipose tissue of obese and NIDDM patients
-
D. Auboeuf, J. Rieusset, L. Fajas, P. Vallier, V. Frering, J.P. Riou, B. Staels, J. Auwerx, M. Laville, and H. Vidal Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: no alteration in adipose tissue of obese and NIDDM patients Diabetes 46 1997 1319 1327
-
(1997)
Diabetes
, vol.46
, pp. 1319-1327
-
-
Auboeuf, D.1
Rieusset, J.2
Fajas, L.3
Vallier, P.4
Frering, V.5
Riou, J.P.6
Staels, B.7
Auwerx, J.8
Laville, M.9
Vidal, H.10
-
75
-
-
0030658022
-
Coordinate regulation of the expression of the fatty acid transport protein and acyl-CoA synthetase genes by PPARalpha and PPARgamma activators
-
G. Martin, K. Schoonjans, A.M. Lefebvre, B. Staels, and J. Auwerx Coordinate regulation of the expression of the fatty acid transport protein and acyl-CoA synthetase genes by PPARalpha and PPARgamma activators J. Biol. Chem. 272 1997 28210 28217
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 28210-28217
-
-
Martin, G.1
Schoonjans, K.2
Lefebvre, A.M.3
Staels, B.4
Auwerx, J.5
-
76
-
-
0032479423
-
Expression of putative fatty acid transporter genes are regulated by peroxisome proliferator-activated receptor alpha and gamma activators in a tissue- and inducer-specific manner
-
K. Motojima, P. Passilly, J.M. Peters, F.J. Gonzalez, and N. Latruffe Expression of putative fatty acid transporter genes are regulated by peroxisome proliferator-activated receptor alpha and gamma activators in a tissue- and inducer-specific manner J. Biol. Chem. 273 1998 16710 16714
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 16710-16714
-
-
Motojima, K.1
Passilly, P.2
Peters, J.M.3
Gonzalez, F.J.4
Latruffe, N.5
-
77
-
-
0027278522
-
Positive regulation of the peroxisomal beta-oxidation pathway by fatty acids through activation of peroxisome proliferator-activated receptors (PPAR)
-
C. Dreyer, H. Keller, A. Mahfoudi, V. Laudet, G. Krey, and W. Wahli Positive regulation of the peroxisomal beta-oxidation pathway by fatty acids through activation of peroxisome proliferator-activated receptors (PPAR) Biol. Cell 77 1993 67 76
-
(1993)
Biol. Cell
, vol.77
, pp. 67-76
-
-
Dreyer, C.1
Keller, H.2
Mahfoudi, A.3
Laudet, V.4
Krey, G.5
Wahli, W.6
-
78
-
-
0029791412
-
PPARalpha and PPARgamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene
-
K. Schoonjans, J. Peinado-Onsurbe, A.M. Lefebvre, R.A. Heyman, M. Briggs, S. Deeb, B. Staels, and J. Auwerx PPARalpha and PPARgamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene EMBO J. 15 1996 5336 5348
-
(1996)
EMBO J.
, vol.15
, pp. 5336-5348
-
-
Schoonjans, K.1
Peinado-Onsurbe, J.2
Lefebvre, A.M.3
Heyman, R.A.4
Briggs, M.5
Deeb, S.6
Staels, B.7
Auwerx, J.8
-
79
-
-
77954987061
-
PPARalpha: Energy combustion, hypolipidemia, inflammation and cancer
-
10.1621/nrs.08002
-
S.R. Pyper, N. Viswakarma, S. Yu, and J.K. Reddy PPARalpha: energy combustion, hypolipidemia, inflammation and cancer Nucl. Recept. Signal 8 2010 e002 10.1621/nrs.08002
-
(2010)
Nucl. Recept. Signal
, vol.8
, pp. 002
-
-
Pyper, S.R.1
Viswakarma, N.2
Yu, S.3
Reddy, J.K.4
-
80
-
-
0030952937
-
Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta
-
B.M. Forman, J. Chen, and R.M. Evans Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta Proc. Natl. Acad. Sci. U.S.A. 94 1997 4312 4317
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 4312-4317
-
-
Forman, B.M.1
Chen, J.2
Evans, R.M.3
-
81
-
-
68149098866
-
Identification of a physiologically relevant endogenous ligand for PPARalpha in liver
-
10.1016/j.cell.2009.05.036
-
M.V. Chakravarthy, I.J. Lodhi, L. Yin, R.R. Malapaka, H.E. Xu, J. Turk, and C.F. Semenkovich Identification of a physiologically relevant endogenous ligand for PPARalpha in liver Cell 138 2009 476 488 10.1016/j.cell.2009.05.036
-
(2009)
Cell
, vol.138
, pp. 476-488
-
-
Chakravarthy, M.V.1
Lodhi, I.J.2
Yin, L.3
Malapaka, R.R.4
Xu, H.E.5
Turk, J.6
Semenkovich, C.F.7
-
82
-
-
84864864825
-
PPAR-gamma as a therapeutic target in cardiovascular disease: Evidence and uncertainty
-
10.1194/jlr.R024505
-
J.V. Huang, C.R. Greyson, and G.G. Schwartz PPAR-gamma as a therapeutic target in cardiovascular disease: evidence and uncertainty J. Lipid Res. 53 2012 1738 1754 10.1194/jlr.R024505
-
(2012)
J. Lipid Res.
, vol.53
, pp. 1738-1754
-
-
Huang, J.V.1
Greyson, C.R.2
Schwartz, G.G.3
-
83
-
-
70349113042
-
Role of PPAR-gamma in inflammation. Prospects for therapeutic intervention by food components
-
10.1016/j.mrfmmm.2009.06.009
-
H. Martin Role of PPAR-gamma in inflammation. Prospects for therapeutic intervention by food components Mutat. Res. 669 2009 1 7 10.1016/j.mrfmmm.2009. 06.009
-
(2009)
Mutat. Res.
, vol.669
, pp. 1-7
-
-
Martin, H.1
-
84
-
-
84871332422
-
Novel keto-phospholipids are generated by monocytes and macrophages, detected in cystic fibrosis, and activate peroxisome proliferator-activated receptor-gamma
-
10.1074/jbc.M112.405407
-
V.J. Hammond, A.H. Morgan, S. Lauder, C.P. Thomas, S. Brown, B.A. Freeman, C.M. Lloyd, J. Davies, A. Bush, and A.L. Levonen Novel keto-phospholipids are generated by monocytes and macrophages, detected in cystic fibrosis, and activate peroxisome proliferator-activated receptor-gamma J. Biol. Chem. 287 2012 41651 41666 10.1074/jbc.M112.405407
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 41651-41666
-
-
Hammond, V.J.1
Morgan, A.H.2
Lauder, S.3
Thomas, C.P.4
Brown, S.5
Freeman, B.A.6
Lloyd, C.M.7
Davies, J.8
Bush, A.9
Levonen, A.L.10
-
85
-
-
0035844217
-
Oxidized alkyl phospholipids are specific, high affinity peroxisome proliferator-activated receptor gamma ligands and agonists
-
10.1074/jbc.M100878200
-
S.S. Davies, A.V. Pontsler, G.K. Marathe, K.A. Harrison, R.C. Murphy, J.C. Hinshaw, G.D. Prestwich, A.S. Hilaire, S.M. Prescott, and G.A. Zimmerman Oxidized alkyl phospholipids are specific, high affinity peroxisome proliferator-activated receptor gamma ligands and agonists J. Biol. Chem. 276 2001 16015 16023 10.1074/jbc.M100878200
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 16015-16023
-
-
Davies, S.S.1
Pontsler, A.V.2
Marathe, G.K.3
Harrison, K.A.4
Murphy, R.C.5
Hinshaw, J.C.6
Prestwich, G.D.7
Hilaire, A.S.8
Prescott, S.M.9
Zimmerman, G.A.10
-
86
-
-
0034616072
-
Oxidized phospholipids activate PPARalpha in a phospholipase A2-dependent manner
-
P. Delerive, C. Furman, E. Teissier, J. Fruchart, P. Duriez, and B. Staels Oxidized phospholipids activate PPARalpha in a phospholipase A2-dependent manner FEBS Lett. 471 2000 34 38
-
(2000)
FEBS Lett.
, vol.471
, pp. 34-38
-
-
Delerive, P.1
Furman, C.2
Teissier, E.3
Fruchart, J.4
Duriez, P.5
Staels, B.6
-
87
-
-
0025091575
-
Relationship between the product of the Drosophila ultraspiracle locus and the vertebrate retinoid X receptor
-
10.1038/347298a0
-
A.E. Oro, M. McKeown, and R.M. Evans Relationship between the product of the Drosophila ultraspiracle locus and the vertebrate retinoid X receptor Nature 347 1990 298 301 10.1038/347298a0
-
(1990)
Nature
, vol.347
, pp. 298-301
-
-
Oro, A.E.1
McKeown, M.2
Evans, R.M.3
-
88
-
-
0025354124
-
A steroid/thyroid hormone receptor superfamily member in Drosophila melanogaster that shares extensive sequence similarity with a mammalian homologue
-
V.C. Henrich, T.J. Sliter, D.B. Lubahn, A. MacIntyre, and L.I. Gilbert A steroid/thyroid hormone receptor superfamily member in Drosophila melanogaster that shares extensive sequence similarity with a mammalian homologue Nucleic Acids Res. 18 1990 4143 4148
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 4143-4148
-
-
Henrich, V.C.1
Sliter, T.J.2
Lubahn, D.B.3
MacIntyre, A.4
Gilbert, L.I.5
-
89
-
-
84857783131
-
Ecdysone signaling in adult Drosophila melanogaster
-
10.1016/j.jinsphys.2012.01.013
-
C.C. Schwedes, and G.E. Carney Ecdysone signaling in adult Drosophila melanogaster J. Insect Physiol. 58 2012 293 302 10.1016/j.jinsphys.2012.01.013
-
(2012)
J. Insect Physiol.
, vol.58
, pp. 293-302
-
-
Schwedes, C.C.1
Carney, G.E.2
-
90
-
-
0031457543
-
Ultraspiracle: An invertebrate nuclear receptor for juvenile hormones
-
G. Jones, and P.A. Sharp Ultraspiracle: an invertebrate nuclear receptor for juvenile hormones Proc. Natl. Acad. Sci. U.S.A. 94 1997 13499 13503
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 13499-13503
-
-
Jones, G.1
Sharp, P.A.2
-
91
-
-
34447092112
-
Farnesoid secretions of dipteran ring glands: What we do know and what we can know
-
10.1016/j.ibmb.2007.05.014
-
D. Jones, and G. Jones Farnesoid secretions of dipteran ring glands: what we do know and what we can know Insect Biochem. Mol. Biol. 37 2007 771 798 10.1016/j.ibmb.2007.05.014
-
(2007)
Insect Biochem. Mol. Biol.
, vol.37
, pp. 771-798
-
-
Jones, D.1
Jones, G.2
-
92
-
-
0035852767
-
The structure of the ultraspiracle ligand-binding domain reveals a nuclear receptor locked in an inactive conformation
-
G.M. Clayton, S.Y. Peak-Chew, R.M. Evans, and J.W. Schwabe The structure of the ultraspiracle ligand-binding domain reveals a nuclear receptor locked in an inactive conformation Proc. Natl. Acad. Sci. U.S.A. 98 2001 1549 1554
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 1549-1554
-
-
Clayton, G.M.1
Peak-Chew, S.Y.2
Evans, R.M.3
Schwabe, J.W.4
-
93
-
-
0035831522
-
Crystal structure of the ligand-binding domain of the ultraspiracle protein USP, the ortholog of retinoid X receptors in insects
-
I.M. Billas, L. Moulinier, N. Rochel, and D. Moras Crystal structure of the ligand-binding domain of the ultraspiracle protein USP, the ortholog of retinoid X receptors in insects J. Biol. Chem. 276 2001 7465 7474
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 7465-7474
-
-
Billas, I.M.1
Moulinier, L.2
Rochel, N.3
Moras, D.4
-
94
-
-
0242413983
-
Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor
-
10.1038/nature02112
-
I.M. Billas, T. Iwema, J.M. Garnier, A. Mitschler, N. Rochel, and D. Moras Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor Nature 426 2003 91 96 10.1038/nature02112
-
(2003)
Nature
, vol.426
, pp. 91-96
-
-
Billas, I.M.1
Iwema, T.2
Garnier, J.M.3
Mitschler, A.4
Rochel, N.5
Moras, D.6
-
95
-
-
36348974463
-
Critical role of desolvation in the binding of 20-hydroxyecdysone to the ecdysone receptor
-
10.1074/jbc.M705559200
-
C. Browning, E. Martin, C. Loch, J.M. Wurtz, D. Moras, R.H. Stote, A.P. Dejaegere, and I.M. Billas Critical role of desolvation in the binding of 20-hydroxyecdysone to the ecdysone receptor J. Biol. Chem. 282 2007 32924 32934 10.1074/jbc.M705559200
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 32924-32934
-
-
Browning, C.1
Martin, E.2
Loch, C.3
Wurtz, J.M.4
Moras, D.5
Stote, R.H.6
Dejaegere, A.P.7
Billas, I.M.8
-
96
-
-
0035342462
-
Adaptations of the helix-grip fold for ligand binding and catalysis in the START domain superfamily
-
L.M. Iyer, E.V. Koonin, and L. Aravind Adaptations of the helix-grip fold for ligand binding and catalysis in the START domain superfamily Proteins 43 2001 134 144
-
(2001)
Proteins
, vol.43
, pp. 134-144
-
-
Iyer, L.M.1
Koonin, E.V.2
Aravind, L.3
-
97
-
-
0032901292
-
START: A lipid-binding domain in StAR, HD-ZIP and signalling proteins
-
C.P. Ponting, and L. Aravind START: a lipid-binding domain in StAR, HD-ZIP and signalling proteins Trends Biochem. Sci. 24 1999 130 132
-
(1999)
Trends Biochem. Sci.
, vol.24
, pp. 130-132
-
-
Ponting, C.P.1
Aravind, L.2
-
98
-
-
0036294612
-
Structure of human phosphatidylcholine transfer protein in complex with its ligand
-
10.1038/nsb812
-
S.L. Roderick, W.W. Chan, D.S. Agate, L.R. Olsen, M.W. Vetting, K.R. Rajashankar, and D.E. Cohen Structure of human phosphatidylcholine transfer protein in complex with its ligand Nat. Struct. Biol. 9 2002 507 511 10.1038/nsb812
-
(2002)
Nat. Struct. Biol.
, vol.9
, pp. 507-511
-
-
Roderick, S.L.1
Chan, W.W.2
Agate, D.S.3
Olsen, L.R.4
Vetting, M.W.5
Rajashankar, K.R.6
Cohen, D.E.7
-
99
-
-
0019319507
-
Phosphatidylcholine exchange protein catalyzes the net transfer of phosphatidylcholine to model membranes
-
K.W. Wirtz, P.F. Devaux, and A. Bienvenue Phosphatidylcholine exchange protein catalyzes the net transfer of phosphatidylcholine to model membranes Biochemistry 19 1980 3395 3399
-
(1980)
Biochemistry
, vol.19
, pp. 3395-3399
-
-
Wirtz, K.W.1
Devaux, P.F.2
Bienvenue, A.3
-
100
-
-
0017356552
-
Specificity of the phosphatidylcholine exchange protein from bovine liver
-
H.H. Kamp, W.A. Wirtz, P.R. Baer, A.J. Slotboom, A.F. Rosenthal, F. Paltauf, and L.L. van Deenem Specificity of the phosphatidylcholine exchange protein from bovine liver Biochemistry 16 1977 1310 1316
-
(1977)
Biochemistry
, vol.16
, pp. 1310-1316
-
-
Kamp, H.H.1
Wirtz, W.A.2
Baer, P.R.3
Slotboom, A.J.4
Rosenthal, A.F.5
Paltauf, F.6
Van Deenem, L.L.7
-
101
-
-
0016424607
-
Catalytic properties of phospholipid exchange protein from bovine heart
-
L.W. Johnson, and D.B. Zilversmit Catalytic properties of phospholipid exchange protein from bovine heart Biochim. Biophys. Acta 375 1975 165 175
-
(1975)
Biochim. Biophys. Acta
, vol.375
, pp. 165-175
-
-
Johnson, L.W.1
Zilversmit, D.B.2
-
102
-
-
77954309627
-
PC-TP/StARD2: Of membranes and metabolism
-
10.1016/j.tem.2010.02.001
-
H.W. Kang, J. Wei, and D.E. Cohen PC-TP/StARD2: Of membranes and metabolism Trends Endocrinol. Metab. 21 2010 449 456 10.1016/j.tem.2010.02.001
-
(2010)
Trends Endocrinol. Metab.
, vol.21
, pp. 449-456
-
-
Kang, H.W.1
Wei, J.2
Cohen, D.E.3
-
103
-
-
35648957162
-
Interacting proteins dictate function of the minimal START domain phosphatidylcholine transfer protein/StarD2
-
10.1074/jbc.M703745200
-
K. Kanno, M.K. Wu, D.S. Agate, B.J. Fanelli, N. Wagle, E.F. Scapa, C. Ukomadu, and D.E. Cohen Interacting proteins dictate function of the minimal START domain phosphatidylcholine transfer protein/StarD2 J. Biol. Chem. 282 2007 30728 30736 10.1074/jbc.M703745200
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 30728-30736
-
-
Kanno, K.1
Wu, M.K.2
Agate, D.S.3
Fanelli, B.J.4
Wagle, N.5
Scapa, E.F.6
Ukomadu, C.7
Cohen, D.E.8
-
104
-
-
76549119341
-
Regulatory role for phosphatidylcholine transfer protein/StarD2 in the metabolic response to peroxisome proliferator activated receptor alpha (PPARalpha)
-
10.1016/j.bbalip.2009.12.013
-
H.W. Kang, K. Kanno, E.F. Scapa, and D.E. Cohen Regulatory role for phosphatidylcholine transfer protein/StarD2 in the metabolic response to peroxisome proliferator activated receptor alpha (PPARalpha) Biochim. Biophys. Acta 1801 2010 496 502 10.1016/j.bbalip.2009.12.013
-
(2010)
Biochim. Biophys. Acta
, vol.1801
, pp. 496-502
-
-
Kang, H.W.1
Kanno, K.2
Scapa, E.F.3
Cohen, D.E.4
-
105
-
-
26444502629
-
Identification of an ITPase/XTPase in Escherichia coli by structural and biochemical analysis
-
10.1016/j.str.2005.07.007
-
J. Zheng, V.K. Singh, and Z. Jia Identification of an ITPase/XTPase in Escherichia coli by structural and biochemical analysis Structure 13 2005 1511 1520 10.1016/j.str.2005.07.007
-
(2005)
Structure
, vol.13
, pp. 1511-1520
-
-
Zheng, J.1
Singh, V.K.2
Jia, Z.3
-
106
-
-
23244459501
-
Crystal structure of mouse CD1d bound to the self ligand phosphatidylcholine: A molecular basis for NKT cell activation
-
B. Giabbai, S. Sidobre, M.D. Crispin, Y. Sanchez-Ruiz, A. Bachi, M. Kronenberg, I.A. Wilson, and M. Degano Crystal structure of mouse CD1d bound to the self ligand phosphatidylcholine: a molecular basis for NKT cell activation J. Immunol. 175 2005 977 984
-
(2005)
J. Immunol.
, vol.175
, pp. 977-984
-
-
Giabbai, B.1
Sidobre, S.2
Crispin, M.D.3
Sanchez-Ruiz, Y.4
Bachi, A.5
Kronenberg, M.6
Wilson, I.A.7
Degano, M.8
-
107
-
-
0035984523
-
Structure of human CD1b with bound ligands at 2.3 A, a maze for alkyl chains
-
10.1038/ni821
-
S.D. Gadola, N.R. Zaccai, K. Harlos, D. Shepherd, J.C. Castro-Palomino, G. Ritter, R.R. Schmidt, E.Y. Jones, and V. Cerundolo Structure of human CD1b with bound ligands at 2.3 A, a maze for alkyl chains Nat. Immunol. 3 2002 721 726 10.1038/ni821
-
(2002)
Nat. Immunol.
, vol.3
, pp. 721-726
-
-
Gadola, S.D.1
Zaccai, N.R.2
Harlos, K.3
Shepherd, D.4
Castro-Palomino, J.C.5
Ritter, G.6
Schmidt, R.R.7
Jones, E.Y.8
Cerundolo, V.9
-
108
-
-
0030925211
-
CD1 presentation of microbial nonpeptide antigens to T cells
-
10.1172/JCI119378
-
D. Jullien, S. Stenger, W.A. Ernst, and R.L. Modlin CD1 presentation of microbial nonpeptide antigens to T cells J. Clin. Invest. 99 1997 2071 2074 10.1172/JCI119378
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 2071-2074
-
-
Jullien, D.1
Stenger, S.2
Ernst, W.A.3
Modlin, R.L.4
-
109
-
-
77649159735
-
The Sec14 superfamily and mechanisms for crosstalk between lipid metabolism and lipid signaling
-
10.1016/j.tibs.2009.10.008
-
V.A. Bankaitis, C.J. Mousley, and G. Schaaf The Sec14 superfamily and mechanisms for crosstalk between lipid metabolism and lipid signaling Trends Biochem. Sci. 35 2010 150 160 10.1016/j.tibs.2009.10.008
-
(2010)
Trends Biochem. Sci.
, vol.35
, pp. 150-160
-
-
Bankaitis, V.A.1
Mousley, C.J.2
Schaaf, G.3
-
110
-
-
38649109468
-
Functional anatomy of phospholipid binding and regulation of phosphoinositide homeostasis by proteins of the sec14 superfamily
-
10.1016/j.molcel.2007.11.026
-
G. Schaaf, E.A. Ortlund, K.R. Tyeryar, C.J. Mousley, K.E. Ile, T.A. Garrett, J. Ren, M.J. Woolls, C.R. Raetz, and M.R. Redinbo Functional anatomy of phospholipid binding and regulation of phosphoinositide homeostasis by proteins of the sec14 superfamily Mol. Cell 29 2008 191 206 10.1016/j.molcel.2007.11.026
-
(2008)
Mol. Cell
, vol.29
, pp. 191-206
-
-
Schaaf, G.1
Ortlund, E.A.2
Tyeryar, K.R.3
Mousley, C.J.4
Ile, K.E.5
Garrett, T.A.6
Ren, J.7
Woolls, M.J.8
Raetz, C.R.9
Redinbo, M.R.10
-
111
-
-
0038784526
-
The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor
-
O. Gozani, P. Karuman, D.R. Jones, D. Ivanov, J. Cha, A.A. Lugovskoy, C.L. Baird, H. Zhu, S.J. Field, and S.L. Lessnick The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor Cell 114 2003 99 111
-
(2003)
Cell
, vol.114
, pp. 99-111
-
-
Gozani, O.1
Karuman, P.2
Jones, D.R.3
Ivanov, D.4
Cha, J.5
Lugovskoy, A.A.6
Baird, C.L.7
Zhu, H.8
Field, S.J.9
Lessnick, S.L.10
-
112
-
-
27944442420
-
Orphan nuclear receptors adopted by crystallography
-
10.1016/j.sbi.2005.10.009
-
Ha Ingraham, and M.R. Redinbo Orphan nuclear receptors adopted by crystallography Curr. Opin. Struct. Biol. 15 2005 708 715 10.1016/j.sbi.2005.10. 009
-
(2005)
Curr. Opin. Struct. Biol.
, vol.15
, pp. 708-715
-
-
Ingraham, H.1
Redinbo, M.R.2
-
113
-
-
0035102591
-
Probing conformational changes in the estrogen receptor: Evidence for a partially unfolded intermediate facilitating ligand binding and release
-
A.C. Gee, and J.A. Katzenellenbogen Probing conformational changes in the estrogen receptor: evidence for a partially unfolded intermediate facilitating ligand binding and release Mol. Endocrinol. 15 2001 421 428
-
(2001)
Mol. Endocrinol.
, vol.15
, pp. 421-428
-
-
Gee, A.C.1
Katzenellenbogen, J.A.2
-
114
-
-
1242283841
-
Structure-function analysis of human [corrected] phosphatidylinositol transfer protein alpha bound to phosphatidylinositol
-
10.1016/j.str.2004.01.013
-
S.J. Tilley, A. Skippen, J. Murray-Rust, P.M. Swigart, A. Stewart, C.P. Morgan, S. Cockcroft, and N.Q. McDonald Structure-function analysis of human [corrected] phosphatidylinositol transfer protein alpha bound to phosphatidylinositol Structure 12 2004 317 326 10.1016/j.str.2004.01.013
-
(2004)
Structure
, vol.12
, pp. 317-326
-
-
Tilley, S.J.1
Skippen, A.2
Murray-Rust, J.3
Swigart, P.M.4
Stewart, A.5
Morgan, C.P.6
Cockcroft, S.7
McDonald, N.Q.8
|