Identification of the first synthetic steroidogenic factor 1 inverse agonists: Pharmacological modulation of steroidogenic enzymes

Molecular Pharmacology

Volumn 73, Issue 3, 2008, Pages 900-908

  Del Tredici, Andria L ^a   Andersen, Carsten B ^a   Currier, Erika A ^a   Ohrmund, Steven R ^a   Fairbain, Luke C ^a   Lund, Birgitte W ^b   Nash, Norman ^a   Olsson, Roger ^b   Piu, Fabrice ^a  

^a ACADIA PHARMACEUTICALS INC   (United States)

^b ACADIA Pharmaceuticals AB   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

4 (BUTOXY)PHENOL; 4 (DECYLOXY)PHENOL; 4 (HEPTYLOXY)PHENOL; 4 (HEXYLOXY)PHENOL; 4 (OCTYLOXY)PHENOL; 4 (PENTYLOXY)PHENOL; AC 45594; PHENOL DERIVATIVE; STEROIDOGENIC FACTOR 1; STEROIDOGENIC FACTOR 1 INVERSE AGONIST; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG SCREENING; GENE EXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ADRENAL GLAND NEOPLASMS; ANIMALS; CARCINOMA; CELL PROLIFERATION; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; CYCLIC AMP; DRUG EVALUATION, PRECLINICAL; GENES, REPORTER; HUMANS; INHIBITORY CONCENTRATION 50; LIGANDS; LUCIFERASES; MICE; MUTATION; NIH 3T3 CELLS; PHENOLS; RNA, MESSENGER; STEROIDOGENIC FACTOR 1; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 40849111661     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.107.040089     Document Type: Article

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