Involvement of ASK1-p38 pathway in the pathogenesis of diabetes triggered by pancreatic ß cell exhaustion

Biochimica et Biophysica Acta - General Subjects

Volumn 1830, Issue 6, 2013, Pages 3656-3663

  Yamaguchi, Kiyoshi ^a,b   Takeda, Kohsuke ^a,c   Kadowaki, Hisae ^a,d   Ueda, Ikumi ^a   Namba, Yoshio ^b,e   Ouchi, Yasuyoshi ^b   Nishitoh, Hideki ^a,d   Ichijo, Hidenori ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c NAGASAKI UNIVERSITY   (Japan)

^d UNIVERSITY OF MIYAZAKI   (Japan)

^e Cabinet Office   (Japan)

Author keywords

Akita mouse; Apoptosis; ASK1; Diabetes; ER stress; p38

Indexed keywords

APOPTOSIS SIGNAL REGULATING KINASE 1; SYNAPTOPHYSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; DIABETES MELLITUS; ENDOPLASMIC RETICULUM STRESS; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

AMINO ACID SUBSTITUTION; ANIMALS; CELL DEATH; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME INHIBITORS; HEK293 CELLS; HUMANS; IMIDAZOLES; INSULIN; INSULIN-SECRETING CELLS; MAP KINASE KINASE KINASE 5; MAP KINASE SIGNALING SYSTEM; MICE; MICE, KNOCKOUT; MUTATION, MISSENSE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRIDINES;

ANIMALIA; MUS;

EID: 84875992503     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2013.01.029     Document Type: Article

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