Role of pancreatic β-cell death and cell death-associated inflammation in diabetes

Current Molecular Medicine

Volumn 12, Issue 10, 2012, Pages 1297-1310

  Lee, M S ^a   Kim, K A ^b   Kim, H S ^c  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Dongguk University Ilsan Hospital   (South Korea)

^c University of Ulsan   (South Korea)

Author keywords

cell death; Apoptosis; Autophagy; Diabetes; Innate immunity; Necrosis

Indexed keywords

ADENOSINE TRIPHOSPHATE; AMYLOID PROTEIN; AUTOPHAGY PROTEIN 7; BECLIN 1; CASPASE; FAS LIGAND; FATTY ACID; GAMMA INTERFERON; HEAT SHOCK PROTEIN; HISTONE DEACETYLASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; NITRIC OXIDE; OXYGEN RADICAL; PALMITIC ACID; PROTEIN; PROTEIN S 100; RAB PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; STAT PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; URIC ACID;

APOPTOSIS; AUTOPHAGOSOME; AUTOPHAGY; CELL DEATH; CELL INFILTRATION; CELL PERMEABILIZATION; CELL STRESS; DIABETES MELLITUS; DNA DAMAGE; ENDOPLASMIC RETICULUM; EXOCYTOSIS; HOMEOSTASIS; HUMAN; HYPERGLYCEMIA; IMMUNE RESPONSE; INFLAMMATION; INSULIN DEPENDENT DIABETES MELLITUS; NECROSIS; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PROTEIN DEGRADATION; REVIEW; SIGNAL TRANSDUCTION;

APOPTOSIS; AUTOPHAGY; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; HUMANS; IMMUNITY, INNATE; INFLAMMATION; INSULIN-SECRETING CELLS; NECROSIS;

EID: 84870214019     PISSN: 15665240     EISSN: 18755666     Source Type: Journal    
DOI: 10.2174/156652412803833553     Document Type: Review

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