Chromatin collapse during caspase-dependent apoptotic cell death requires DNA fragmentation factor, 40-kDa subunit-/caspase-activated deoxyribonuclease- mediated 3′-OH single-strand DNA breaks

Journal of Biological Chemistry

Volumn 288, Issue 13, 2013, Pages 9200-9215

  Iglesias Guimarais, Victoria ^a,b,c   Gil Guiñon, Estel ^a   Sánchez Osuna, María ^a   Casanelles, Elisenda ^a,b,c   García Belinchón, Mercè ^a   Comella, Joan X ^b,c   Yuste, Victor J ^a,c  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^c CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOTIC CELL DEATH; CHROMATIN COMPACTION; CHROMATIN CONDENSATION; DEOXYRIBONUCLEASE; DNA FRAGMENTATION FACTORS; DOUBLE-STRAND DNAS; NUCLEAR MORPHOLOGY; SINGLE-STRAND BREAKS;

CELL DEATH; CHROMOSOMES; COMPUTER AIDED DESIGN; ELECTROPHORESIS; MORPHOLOGY;

DNA;

CASPASE ACTIVATED DEOXYRIBONUCLEASE; STAUROSPORINE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL ASSAY; CELL COUNT; CELL STRUCTURE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMATIN CONDENSATION; CONTROLLED STUDY; DNA DAMAGE; DNA DEGRADATION; DNA DETERMINATION; DOUBLE STRANDED DNA BREAK; DOWN REGULATION; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MOUSE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SINGLE STRANDED DNA BREAK; UPREGULATION;

ANIMALS; APOPTOSIS; BISBENZIMIDAZOLE; CASPASES; CELL DEATH; CELL LINE; CELL NUCLEUS; CHROMATIN; CLONING, MOLECULAR; DEOXYRIBONUCLEASES; DNA; DNA BREAKS, SINGLE-STRANDED; DNA DAMAGE; DNA FRAGMENTATION; ENDONUCLEASES; FLOW CYTOMETRY; HUMANS; MICE; MODELS, BIOLOGICAL; MUTATION; NEUROBLASTOMA; NUCLEOSOMES; TRYPAN BLUE;

EID: 84875973253     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.411371     Document Type: Article

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