Methadone induces CAD degradation and AIF-mediated necrotic-like cell death in neuroblastoma cells

Pharmacological Research

Volumn 63, Issue 4, 2011, Pages 352-360

  Perez Alvarez, Sergio ^a   Iglesias Guimarais, Victoria ^b   Solesio, María E ^c   Melero Fernandez De Mera, Raquel María ^a   Yuste, Víctor J ^b   Galindo, María F ^c   Jordán, Joaquín ^a  

^a UNIVERSITY OF CASTILLA LA MANCHA   (Spain)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^c Hospital de Albacete   (Spain)

Author keywords

Drug abuse; Mitochondria; Necrosis

Indexed keywords

APOPTOSIS INDUCING FACTOR; CASPASE ACTIVATED DEOXYRIBONUCLEASE; CYCLOSPORIN A; DNA FRAGMENT; HISTONE H2AX; METHADONE; PROTEIN BAX;

ADVERSE OUTCOME; ANIMAL CELL; ARTICLE; CELL DEATH; CONTROLLED STUDY; DNA DEGRADATION; DNA FRAGMENTATION; EMBRYO; ENZYME DEGRADATION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL PERMEABILITY; MOLECULAR WEIGHT; MOUSE; NECROSIS; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANALGESICS, OPIOID; ANIMALS; APOPTOSIS INDUCING FACTOR; BCL-2-ASSOCIATED X PROTEIN; CELL LINE, TUMOR; HISTONES; HUMANS; METHADONE; MICE; MITOCHONDRIA; NECROSIS; NEUROBLASTOMA; PROTEIN TRANSPORT;

EID: 79951810838     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2010.12.001     Document Type: Article

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