Apoptotic DNA degradation into oligonucleosomal fragments, but not apoptotic nuclear morphology, relies on a cytosolic pool of DFF40/CAD endonuclease

Journal of Biological Chemistry

Volumn 287, Issue 10, 2012, Pages 7766-7779

  Iglesias Guimarais, Victoria ^a,b   Gil Guiñon, Estel ^a   Gabernet, Gisela ^a   García Belinchón, Mercè ^a   Sánchez Osuna, María ^a   Casanelles, Elisenda ^a,b   Comella, Joan X ^b   Yuste, Victor J ^a,b  

^a INSTITUT DE NEUROCIÈNCIES   (Spain)

^b HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID COMPOSITIONS; APOPTOTIC; APOPTOTIC CELL DEATH; APOPTOTIC STIMULI; CDNA SEQUENCE; CELL LINES; CYTOSOLIC; CYTOSOLIC FRACTIONS; DNA DEGRADATION; DNA FRAGMENTATION; DNA LADDERING; ENDOGENOUS INHIBITOR; ENDONUCLEASES; LOW LEVEL; NUCLEAR FRAGMENTATION; NUCLEAR MORPHOLOGY; OVER-EXPRESSION; RESTING CELLS; STAUROSPORINES; SUBCELLULAR DISTRIBUTION; SUBCELLULAR LOCALIZATIONS;

AMINO ACIDS; CELL CULTURE; CELL DEATH; CHROMOSOMES; DEGRADATION; MORPHOLOGY;

DNA;

CASPASE 3; CASPASE ACTIVATED DEOXYRIBONUCLEASE; COMPLEMENTARY DNA;

AMINO ACID COMPOSITION; APOPTOSIS; ARTICLE; CELL DEATH; CELL SIZE; CELLULAR DISTRIBUTION; CHROMATIN; CONTROLLED STUDY; CYTOTOXICITY; DNA DEGRADATION; DNA SEQUENCE; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE MUTATION; GENE OVEREXPRESSION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; NUCLEOSOME; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASPASE 3; CELL LINE, TUMOR; DEOXYRIBONUCLEASES; DNA FRAGMENTATION; ENZYME INHIBITORS; HUMANS; MUTATION; STAUROSPORINE;

EID: 84857763922     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.290718     Document Type: Article

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