Preparative isolation and purification of seven main antioxidants from Eucommia ulmoides Oliv. (Du-zhong) leaves using HSCCC guided by DPPH-HPLC experiment

Food Chemistry

Volumn 139, Issue 1-4, 2013, Pages 563-570

  Dai, Xingping ^a   Huang, Qiong ^b   Zhou, Boting ^b   Gong, Zhicheng ^a,b   Liu, Zhaoqian ^b   Shi, Shuyun ^b  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Antioxidant; DPPH HPLC; Eucommia ulmoides; Flavonoid; HSCCC; Iridoid; Phenylpropanoid

Indexed keywords

DPPH-HPLC; EUCOMMIA ULMOIDES; FLAVONOID; HSCCC; IRIDOID; PHENYLPROPANOIDS;

ANTIOXIDANTS; EXPERIMENTS; FATTY ACIDS; SEPARATION;

PURIFICATION;

1,1 DIPHENYL 2 PICRYLHYDRAZYL; ACETIC ACID ETHYL ESTER; ALCOHOL; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BUTANOL; CAFFEIC ACID; CHLOROGENIC ACID; EUCOMMIA ULMOIDES EXTRACT; FERULIC ACID; GENIPOSIDIC ACID; ISOQUERCITRIN; PETROLEUM ETHER; QUERCETIN 3 O SAMBUBIOSIDE; RUTOSIDE; UNCLASSIFIED DRUG; WATER;

ANTIOXIDANT ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; COLUMN CHROMATOGRAPHY; COUNTER CURRENT CHROMATOGRAPHY; DRUG ISOLATION; DRUG PURIFICATION; DRUG STRUCTURE; EUCOMMIACEAE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IC 50; LIQUID LIQUID EXTRACTION; PLANT LEAF; PROTON NUCLEAR MAGNETIC RESONANCE; SOLVENT EFFECT; TU CHUNG;

ANTIOXIDANTS; BIPHENYL COMPOUNDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COUNTERCURRENT DISTRIBUTION; EUCOMMIACEAE; PICRATES; PLANT EXTRACTS; PLANT LEAVES;

EUCOMMIA ULMOIDES;

EID: 84875941716     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2013.02.006     Document Type: Article

References (37)

1. R.B. Ammar, W. Bhouri, M.B. Sghaier, J. Boubaker, I. Skandrani, and A. Neffati Antioxidant and free radical-scavenging properties of three flavonoids isolated from the leaves of Rhamnus alaternus L. (Rhamnaceae): A structure-activity relationship study Food Chemistry 116 2009 164 258
2. P. Arapitsas Identification and qualification of polyphenolic compounds from okra seeds and skins Food Chemistry 110 2008 1041 1045
3. E.J. Cho, T. Yokozawa, D.Y. Rhyu, S.C. Kim, N. Shibahara, and J.C. Park Study on the inhibitory effects of Korean medicinal plants and their main compounds on the 1,1-diphenyl-2-picrylhydrazyl radical Phytomedicine 10 2003 544 551
4. F. Conforti, M. Marrelli, C. Carmela, F. Menichini, P. Valentina, and D. Uzunov Bioactive phytonutrients (omega fatty acids, tocopherols, polyphenols), in vitro inhibition of nitric oxide production and free radical scavenging activity of non-cultivated Mediterranean vegetables Food Chemistry 129 2011 1413 1419
5. F. das Neves Costa, and G.G. Leitão Strategies of solvent system selection for the isolation of flavonoids by countercurrent chromatography Journal of Separation Science 33 2010 336 347
6. J. Deng, W.Y. Cheng, and G.Z. Yang A novel antioxidant activity index (AAU) for natural products using the DPPH assay Food Chemistry 125 2011 1430 1435
7. T. Deyama, S. Nishibe, and Y. Nakazawa Constituents and pharmacological effects of Eucommia and Siberian ginseng Acta Pharmacologica Sinica 22 2001 1057 1070
8. J.M. Duarte-Almeida, A. Salatino, M.I. Genovese, and F.M. Lajolo Phenolic composition and antioxidant activity of culms and sugarcane (Saccharum officinarum L.) products Food Chemistry 125 2011 660 664
9. R.T.S. Frighetto, R.M. Welendorf, E.N. Nigro, N. Frighetto, and A.C. Siani Isolation of ursolic acid from apple peels by high speed counter-current chromatography Food Chemistry 106 2008 767 771
10. R. Guarnaccia, K.M. Madyastha, E. Tegtmeyer, and C.J. Coscia Geniposidic acid, an iridoid glucoside feom Genipa americana Tetrahedron Letters 13 1972 5125 5127
11. T. Hirata, T. Kobayashi, A. Wada, T. Ueda, T. Fujikawa, and H. Miyashita Anti-obesity compounds in green leaves of Eucommia ulmoides Bioorganic & Medicinal Chemistry Letters 21 2011 1786 1791
12. N.D. Hong, Y.S. Rho, D.H. Won, N.J. Kim, and B.S. Cho Studies on the anti-diabetic activity of Eucommia ulmoides Oliver Korean Journal of Pharmacognosy 18 1987 112 117
13. Y. Horii, M. Tanida, J. Shen, T. Hirata, N. Kawamura, and A. Wada Effects of Eucommia leaf extracts on autonomic nerves, body temperature, lipolysis, food intake, and body weight Neuroscience Letters 479 2010 181 186
14. K. Hostettmann, J.L. Wolfender, and C. Terreaux Moden screening techniques for plant extracts Pharmaceutical Biology 39 2001 18 32
15. Y. Ito Golden rules and pitfalls in selecting optimum conditions for high-speed counter-current chromatography Journal of Chromatography A 1065 2005 145 168
16. H.A. Jung, J.C. Park, H.Y. Chung, J. Kim, and J.S. Choi Antioxidant flavonoids and chlorogenic acid from the leaves of Eriobotrya japonica Archives of Pharmacal Research 22 1999 213 218
17. H.Y. Kim, B.H. Moon, H.J. Lee, and D.H. Choi Flavonol glycosides from the leaves of Eucommia ulmoides O. with glycation inhibitory activity Journal of Ethnopharmacology 93 2004 227 230
18. Y.J. Li, J. Chen, Y. Li, Q. Li, Y.F. Zheng, and Y. Fu Screening and characterization of natural antioxidants in four Glycyrrhiza species by liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry Journal of Chromatography A 1218 2011 8181 8191
19. R.R. Majinda, M. Motswaledi, R.D. Waigh, and P.G. Waterman Phenolic and antibacterial constituents of Vahlia capensis Planta Medica 63 1997 268 270
20. Y. Nakazawa Functional and healthy properties of Du-zhong tea and their utilization Food Industry 40 1997 6 15
21. National Commission of Chinese Pharmacopoeia Pharmacopoeia of the People's Republic of China Vol. 1 2010 China Medical Science and Technology Press Beijing p. 154
22. N. Nuengchamnong, K. Krittaship, and K. Ingkaninan Characterisation of phenolic antioxidants in aqueous extract of Orthosiphon grandiflorus tea by LC-ESI-MS/MS coupled to DPPH assay Food Chemistry 127 2011 1287 1293
23. S.A. Park, M.S. Choi, U.J. Jung, M.J. Kim, D.J. Kim, and H.M. Park Eucommia ulmoides Oliver leaf extract increases endogenous antioxidant activity in type 2 diabetic mice Journal of Medical Food 9 2006 474 479
24. S. Rodriguez, A. Marston, J.L. Wolfender, and K. Hostettmann Iridoids and secoiridoids in the Gentianaceae Current Organic Chemistry 2 1998 627 648
25. S.Y. Shi, K.L. Huang, Y.P. Zhang, Y. Zhao, and Q.Z. Du Purification and identification of antiviral components from Laggera pterodonta by high-speed counter-current chromatography Journal of Chromatography B 859 2007 119 124
26. S.Y. Shi, Y.P. Zhang, K.L. Huang, S.Q. Liu, and Y. Zhao Application of preparative high-speed counter-current chromatography for separation and purification of lignans from Taraxacum mongolicum Food Chemistry 108 2008 402 406
27. S.Y. Shi, Y. Zhao, H.H. Zhou, Y.P. Zhang, X.Y. Jiang, and K.L. Huang Identification of antioxidants from Taraxacum mongolicum by high-performance liquid chromatography-diode array detection-radical scavenging detection-electrospray ionization mass spectrometry and nuclear magnetic resonance experiments Journal of Chromatography A 1209 2008 145 152
28. C. Takamura, T. Hirata, T. Ueda, M. Ono, H. Miyashita, and T. Ikeda Iridoids from the green leaves of Eucommia ulmoides Journal of Natural Products 70 2007 1312 1316
29. C. Takamura, T. Hirata, Y. Yamaguchi, M. Ono, H. Miyashita, and T. Ikeda Studies on the chemical constituents of green leaves of Eucommia ulmoides Oliv Journal of Natural Medicines 61 2007 220 221
30. D. Tang, H.J. Li, J. Chen, C.W. Guo, and P. Li Rapid and simple method for screening of natural antioxidants from Chinese herb Flos Lonicerae japonicae by DPPH-HPLC-DAD-TOF/MS Journal of Separation Science 31 2008 3519 3526
31. A. Tapia, J. Rodriguez, C. Theoduloz, S. Lopez, G.E. Feresin, and G. Schmeda-Hirschmann Free radical scavengers and antioxidants from Baccharis grisebachii Journal of Ethnopharmacology 95 2004 155 161
32. X. Wang, Z.J. Zheng, X.F. Guo, J.P. Yuan, and C.C. Zheng Preparative separation of gingerols from Zingiber officinale by high-speed counter-current chromatography using stepwise elution Food Chemistry 125 2011 1476 1480
33. Y.W. Xu, Y. Qi, X. Han, L.N. Xu, Q.W. Xu, and J.Y. Peng Preparative separation of gentiopicrin from Radix gentianae by high-speed counter-current chromatography with macroporous resin Zhongguo Zhongyao Zazhi 32 2007 2595 2597
34. G.C. Yen, and C.L. Hsieh Antioxidant activity of extracts from Du-zhong (Eucommia ulmoides) towards various lipid peroxidation models in vitro Journal of Agricultural and Food Chemistry 46 1998 3952 3957
35. K.D. Yoon, Y.W. Chin, M.H. Yang, and J. Kim Separation of anti-ulcer flavonoids from Artemisia extracts by high-speed countercurrent chromatography Food Chemistry 129 2011 679 683
36. Y.P. Zhang, S.Y. Shi, Y.X. Wang, and K.L. Huang Target-guided isolation and purification of antioxidants from Selaginella sinensis by offline coupling of DPPH-HPLC and HSCCC experiments Journal of Chromatography B 879 2011 191 196
37. T.T. Zhou, G.R. Fan, Z.Y. Hong, Y.F. Chai, and Y.T. Wu Large-scale isolation and purification of geniposide from the fruit of Gardenia jasminoides Ellis by high-speed counter-current chromatography Journal of Chromatography A 1100 2005 76 80