New concept of the pathogenesis of atopic dermatitis: Interplay among the barrier, allergy, and pruritus as a trinity

Journal of Dermatological Science

Volumn 70, Issue 1, 2013, Pages 3-11

  Kabashima, Kenji ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Atopic dermatitis; Filaggrin; Hapten atopy hypothesis; Langerhans cells; Pruritus; Skin barrier

Indexed keywords

ANTIGEN; CYTOKINE; FILAGGRIN; HAPTEN; INTERLEUKIN 31; THYMIC STROMAL LYMPHOPOIETIN;

ALLERGY; ANIMAL EXPERIMENT; ANIMAL MODEL; ATOPIC DERMATITIS; DISEASE PREDISPOSITION; ENVIRONMENTAL FACTOR; FEMALE; GENE MUTATION; HUMAN; HUMAN CELL; KERATINOCYTE; LANGERHANS CELL; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PERMEABILITY BARRIER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PRURITUS; REVIEW; SKIN PERMEABILITY; STRATUM CORNEUM; TH17 CELL; TH2 CELL; TIGHT JUNCTION;

ANIMALS; DERMATITIS, ATOPIC; HAPTENS; HUMANS; HYPERSENSITIVITY; INTERMEDIATE FILAMENT PROTEINS; LANGERHANS CELLS; PRURITUS;

EID: 84875806780     PISSN: 09231811     EISSN: 1873569X     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2013.02.001     Document Type: Review

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