Topically applied semaphorin 3A ointment inhibits scratching behavior and improves skin inflammation in NC/Nga mice with atopic dermatitis

Journal of Dermatological Science

Volumn 66, Issue 1, 2012, Pages 37-43

  Negi, Osamu ^a   Tominaga, Mitsutoshi ^a,c   Tengara, Suhandy ^a   Kamo, Atsuko ^a   Taneda, Kenichi ^b   Suga, Yasushi ^b   Ogawa, Hideoki ^a   Takamori, Kenji ^a,b  

^a JUNTENDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b JUNTENDO UNIVERSITY URAYASU HOSPITAL   (Japan)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Atopic dermatitis; Epidermal keratinocytes; Nerve fibers; Pruritus; Sema3A

Indexed keywords

BETAMETHASONE; BETAMETHASONE DIPROPIONATE; BIOLOGICAL MARKER; HEPARINOID; HIRUDOID SOFT; PETROLATUM; PROTEIN GENE PRODUCT 9.5; RECOMBINANT SEMAPHORIN 3A; SEMAPHORIN 3A; SUBSTANCE P; TACROLIMUS; UNCLASSIFIED DRUG;

ACANTHOSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ATOPIC DERMATITIS; CD4 LYMPHOCYTE COUNT; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; DERMATOPHAGOIDES FARINAE; DRUG EFFICACY; EOSINOPHIL COUNT; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; SCRATCHING; SKIN WATER LOSS;

ADMINISTRATION, TOPICAL; ANIMALS; ANTI-INFLAMMATORY AGENTS; BEHAVIOR, ANIMAL; BETAMETHASONE; DERMATITIS, ATOPIC; DERMATOPHAGOIDES FARINAE; DRUG THERAPY, COMBINATION; EPIDERMIS; IMMUNOSUPPRESSIVE AGENTS; MALE; MICE; MICE, INBRED STRAINS; NERVE ENDINGS; OINTMENTS; PRURITUS; SEMAPHORIN-3A; SPECIFIC PATHOGEN-FREE ORGANISMS; TACROLIMUS;

EID: 84858149476     PISSN: 09231811     EISSN: 1873569X     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2012.01.007     Document Type: Article

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