A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming

Nature Genetics

Volumn 41, Issue 5, 2009, Pages 602-608

  Fallon, Padraic G ^a   Sasaki, Takashi ^b   Sandilands, Aileen ^c   Campbell, Linda E ^c   Saunders, Sean P ^a   Mangan, Niamh E ^a   Callanan, John J ^d   Kawasaki, Hiroshi ^b   Shiohama, Aiko ^b   Kubo, Akiharu ^b   Sundberg, John P ^e   Presland, Richard B ^f   Fleckman, Philip ^f   Shimizu, Nobuyoshi ^b   Kudoh, Jun ^b   Irvine, Alan D ^a,g   Amagai, Masayuki ^b   McLean, W H Irwin ^c  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b KEIO UNIVERSITY   (Japan)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

^d UNIVERSITY COLLEGE DUBLIN   (Ireland)

^e JACKSON LABORATORY   (United States)

^f UNIVERSITY OF WASHINGTON   (United States)

^g OUR LADY S CHILDREN S HOSPITAL   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; ANTIBODY; ANTIGEN; FILAGGRIN; IMMUNOGLOBULIN E;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; ATOPIC DERMATITIS; CONTROLLED STUDY; EPIDERMIS; FEMALE; FILAGGRIN DEFICIENCY; FILAGGRIN GENE; FRAMESHIFT MUTATION; GENE; GENE DELETION; HOMOZYGOSITY; HUMAN; INFLAMMATORY INFILTRATE; LOSS OF FUNCTION MUTATION; MALE; MOUSE; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; SKIN FUNCTION; SKIN INFLAMMATION; SKIN SENSITIZATION; VALIDATION STUDY;

ALLERGENS; ANIMALS; BASE SEQUENCE; DERMATITIS, ATOPIC; FEMALE; FRAMESHIFT MUTATION; GENOTYPE; HOMOZYGOTE; HYPERSENSITIVITY; ICHTHYOSIS VULGARIS; IMMUNOGLOBULIN E; INTERMEDIATE FILAMENT PROTEINS; MALE; MICE; MICE, INBRED STRAINS; MODELS, GENETIC; MOLECULAR SEQUENCE DATA;

MURINAE; MUS;

EID: 66749163178     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.358     Document Type: Article

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