Filaggrin-deficient mice exhibit TH17-dominated skin inflammation and permissiveness to epicutaneous sensitization with protein antigen

Journal of Allergy and Clinical Immunology

Volumn 124, Issue 3, 2009, Pages

  Oyoshi, Michiko K ^a   Murphy, George F ^b   Geha, Raif S ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

allergen; atopic dermatitis; filaggrin; ft ft mice; IL 17; skin

Indexed keywords

ANTIBODY; ANTIGEN; CYTOKINE; FILAGGRIN; GAMMA INTERFERON; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G1 ANTIBODY; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 23; INTERLEUKIN 4; INTERLEUKIN 6; OVALBUMIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ARTICLE; CD4 LYMPHOCYTE COUNT; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE PREDISPOSITION; ECZEMA; FEMALE; HISTOLOGY; IMMUNE RESPONSE; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN DEFECT; SKIN INFLAMMATION; SKIN SENSITIZATION; SPLEEN CELL; TH17 CELL;

EID: 69349088601     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2009.05.042     Document Type: Article

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