Long-term p110α PI3K inactivation exerts a beneficial effect on metabolism

EMBO Molecular Medicine

Volumn 5, Issue 4, 2013, Pages 563-571

  Foukas, Lazaros C ^a   Bilanges, Benoit ^b   Bettedi, Lucia ^a   Pearce, Wayne ^b   Ali, Khaled ^b   Sancho, Sara ^c   Withers, Dominic J ^d   Vanhaesebroeck, Bart ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c Laboratoire Promed   (Switzerland)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Aging; Cancer; Diabetes; Insulin signalling; Obesity

Indexed keywords

INSULIN RECEPTOR SUBSTRATE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE P110ALPHA; PROTEIN KINASE B; UNCLASSIFIED DRUG;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME INACTIVATION; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; HYPERINSULINEMIA; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIFE EXTENSION; LIPID STORAGE; MALE; METABOLIC STRESS; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CLASS I PHOSPHATIDYLINOSITOL 3-KINASES; FATS; FEMALE; GENE SILENCING; GLUCOSE; HUMANS; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; MALE; METABOLIC DISEASES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; TIME FACTORS;

EID: 84875806319     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201201953     Document Type: Article

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