-
1
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori, S., T. Nomura, and S. Sakaguchi. 2003. Control of regulatory T cell development by the transcription factor Foxp3. Science. 299:1057-1061.
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
2
-
-
0037385314
-
An essential role for Scurfin in CD4+CD25+ T regulatory cells
-
Khattri, R., T. Cox, S.A. Yasayko, and F. Ramsdell. 2003. An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat. Immunol. 4:337-342.
-
(2003)
Nat. Immunol
, vol.4
, pp. 337-342
-
-
Khattri, R.1
Cox, T.2
Yasayko, S.A.3
Ramsdell, F.4
-
3
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
-
Fontenot, J.D., M.A. Gavin, and A.Y. Rudensky. 2003. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat. Immunol. 4:330-336.
-
(2003)
Nat. Immunol
, vol.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
4
-
-
15244354286
-
Regulatory T cell lineage specification by the forkhead transcription factor foxp3
-
Fontenot, J.D., J.P. Rasmussen, L.M. Williams, J.L. Dooley, A.G. Farr, and A.Y. Rudensky. 2005. Regulatory T cell lineage specification by the forkhead transcription factor foxp3. Immunity. 22:329-341.
-
(2005)
Immunity
, vol.22
, pp. 329-341
-
-
Fontenot, J.D.1
Rasmussen, J.P.2
Williams, L.M.3
Dooley, J.L.4
Farr, A.G.5
Rudensky, A.Y.6
-
5
-
-
0035162560
-
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
-
Brunkow, M.E., E.W. Jeffery, K.A. Hjerrild, B. Paeper, L.B. Clark, S.A. Yasayko, J.E. Wilkinson, D. Galas, S.F. Ziegler, and F. Ramsdell. 2001. Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat. Genet. 27:68-73.
-
(2001)
Nat. Genet
, vol.27
, pp. 68-73
-
-
Brunkow, M.E.1
Jeffery, E.W.2
Hjerrild, K.A.3
Paeper, B.4
Clark, L.B.5
Yasayko, S.A.6
Wilkinson, J.E.7
Galas, D.8
Ziegler, S.F.9
Ramsdell, F.10
-
6
-
-
0035163909
-
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
-
Wildin, R.S., F. Ramsdell, J. Peake, F. Faravelli, J.L. Casanova, N. Buist, E. Levy-Lahad, M. Mazzella, O. Goulet, L. Perroni, et al. 2001. X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nat. Genet. 27:18-20.
-
(2001)
Nat. Genet
, vol.27
, pp. 18-20
-
-
Wildin, R.S.1
Ramsdell, F.2
Peake, J.3
Faravelli, F.4
Casanova, J.L.5
Buist, N.6
Levy-Lahad, E.7
Mazzella, M.8
Goulet, O.9
Perroni, L.10
-
7
-
-
0034526617
-
JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome
-
Chatila, T.A., F. Blaeser, N. Ho, H.M. Lederman, C. Voulgaropoulos, C. Helms, and A.M. Bowcock. 2000. JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome. J. Clin. Invest. 106:R75-R81.
-
(2000)
J. Clin. Invest
, vol.106
-
-
Chatila, T.A.1
Blaeser, F.2
Ho, N.3
Lederman, H.M.4
Voulgaropoulos, C.5
Helms, C.6
Bowcock, A.M.7
-
8
-
-
34948875308
-
Immune dysregulation, polyendocrinopathy, enteropathy, X-linked: Forkhead box protein 3 mutations and lack of regulatory T cells
-
Torgerson, T.R., and H.D. Ochs. 2007. Immune dysregulation, polyendocrinopathy, enteropathy, X-linked: forkhead box protein 3 mutations and lack of regulatory T cells. J. Allergy Clin. Immunol. 120:744-750.
-
(2007)
J. Allergy Clin. Immunol
, vol.120
, pp. 744-750
-
-
Torgerson, T.R.1
Ochs, H.D.2
-
9
-
-
33846485153
-
Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
-
Kim, J.M., J.P. Rasmussen, and A.Y. Rudensky. 2007. Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice. Nat. Immunol. 8:191-197.
-
(2007)
Nat. Immunol
, vol.8
, pp. 191-197
-
-
Kim, J.M.1
Rasmussen, J.P.2
Rudensky, A.Y.3
-
10
-
-
27544481941
-
A function for interleukin 2 in Foxp3-expressing regulatory T cells
-
Fontenot, J.D., J.P. Rasmussen, M.A. Gavin, and A.Y. Rudensky. 2005. A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nat. Immunol. 6:1142-1151.
-
(2005)
Nat. Immunol
, vol.6
, pp. 1142-1151
-
-
Fontenot, J.D.1
Rasmussen, J.P.2
Gavin, M.A.3
Rudensky, A.Y.4
-
11
-
-
33847153417
-
Foxp3-dependent programme of regulatory T-cell differentiation
-
Gavin, M.A., J.P. Rasmussen, J.D. Fontenot, V. Vasta, V.C. Manganiello, J.A. Beavo, and A.Y. Rudensky. 2007. Foxp3-dependent programme of regulatory T-cell differentiation. Nature. 445:771-775.
-
(2007)
Nature
, vol.445
, pp. 771-775
-
-
Gavin, M.A.1
Rasmussen, J.P.2
Fontenot, J.D.3
Vasta, V.4
Manganiello, V.C.5
Beavo, J.A.6
Rudensky, A.Y.7
-
12
-
-
33847125247
-
Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression
-
Wan, Y.Y., and R.A. Flavell. 2007. Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression. Nature. 445:766-770.
-
(2007)
Nature
, vol.445
, pp. 766-770
-
-
Wan, Y.Y.1
Flavell, R.A.2
-
13
-
-
33947600584
-
Regulatory T cell development in the absence of functional Foxp3
-
Lin, W., D. Haribhai, L.M. Relland, N. Truong, M.R. Carlson, C.B. Williams, and T.A. Chatila. 2007. Regulatory T cell development in the absence of functional Foxp3. Nat. Immunol. 8:359-368.
-
(2007)
Nat. Immunol
, vol.8
, pp. 359-368
-
-
Lin, W.1
Haribhai, D.2
Relland, L.M.3
Truong, N.4
Carlson, M.R.5
Williams, C.B.6
Chatila, T.A.7
-
14
-
-
34247271308
-
Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3
-
Williams, L.M., and A.Y. Rudensky. 2007. Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3. Nat. Immunol. 8:277-284.
-
(2007)
Nat. Immunol
, vol.8
, pp. 277-284
-
-
Williams, L.M.1
Rudensky, A.Y.2
-
15
-
-
33750499991
-
A role for Dicer in immune regulation
-
Cobb, B.S., A. Hertweck, J. Smith, E. O'Connor, D. Graf, T. Cook, S.T. Smale, S. Sakaguchi, F.J. Livesey, A.G. Fisher, and M. Merkenschlager. 2006. A role for Dicer in immune regulation. J. Exp. Med. 203:2519-2527.
-
(2006)
J. Exp. Med
, vol.203
, pp. 2519-2527
-
-
Cobb, B.S.1
Hertweck, A.2
Smith, J.3
O'Connor, E.4
Graf, D.5
Cook, T.6
Smale, S.T.7
Sakaguchi, S.8
Livesey, F.J.9
Fisher, A.G.10
Merkenschlager, M.11
-
16
-
-
34247277666
-
Foxp3 in control of the regulatory T cell lineage
-
Zheng, Y., and A.Y. Rudensky. 2007. Foxp3 in control of the regulatory T cell lineage. Nat. Immunol. 8:457-462.
-
(2007)
Nat. Immunol
, vol.8
, pp. 457-462
-
-
Zheng, Y.1
Rudensky, A.Y.2
-
17
-
-
33847242598
-
Foxp3 occupancy and regulation of key target genes during T-cell stimulation
-
Marson, A., K. Kretschmer, G.M. Frampton, E.S. Jacobsen, J.K. Polansky, K.D. MacIsaac, S.S. Levine, E. Fraenkel, H. von Boehmer, and R.A. Young. 2007. Foxp3 occupancy and regulation of key target genes during T-cell stimulation. Nature. 445:931-935.
-
(2007)
Nature
, vol.445
, pp. 931-935
-
-
Marson, A.1
Kretschmer, K.2
Frampton, G.M.3
Jacobsen, E.S.4
Polansky, J.K.5
MacIsaac, K.D.6
Levine, S.S.7
Fraenkel, E.8
von Boehmer, H.9
Young, R.A.10
-
18
-
-
84984765621
-
Canalization of development by microRNAs
-
Hornstein, E., and N. Shomron. 2006. Canalization of development by microRNAs. Nat. Genet. 38:S20-S24.
-
(2006)
Nat. Genet
, vol.38
-
-
Hornstein, E.1
Shomron, N.2
-
19
-
-
22944433872
-
Aberrant T cell differentiation in the absence of Dicer
-
Muljo, S.A., K.M. Ansel, C. Kanellopoulou, D.M. Livingston, A. Rao, and K. Rajewsky. 2005. Aberrant T cell differentiation in the absence of Dicer. J. Exp. Med. 202:261-269.
-
(2005)
J. Exp. Med
, vol.202
, pp. 261-269
-
-
Muljo, S.A.1
Ansel, K.M.2
Kanellopoulou, C.3
Livingston, D.M.4
Rao, A.5
Rajewsky, K.6
-
20
-
-
44349104241
-
An endogenous small interfering RNA pathway in Drosophila
-
Czech, B., C.D. Malone, R. Zhou, A. Stark, C. Schlingeheyde, M. Dus, N. Perrimon, M. Kellis, J.A. Wohlschlegel, R. Sachidanandam, et al. 2008. An endogenous small interfering RNA pathway in Drosophila. Nature. 453:798-802.
-
(2008)
Nature
, vol.453
, pp. 798-802
-
-
Czech, B.1
Malone, C.D.2
Zhou, R.3
Stark, A.4
Schlingeheyde, C.5
Dus, M.6
Perrimon, N.7
Kellis, M.8
Wohlschlegel, J.A.9
Sachidanandam, R.10
-
21
-
-
44349084754
-
The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs
-
Okamura, K., W.J. Chung, J.G. Ruby, H. Guo, D.P. Bartel, and E.C. Lai. 2008. The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs. Nature. 453:803-806.
-
(2008)
Nature
, vol.453
, pp. 803-806
-
-
Okamura, K.1
Chung, W.J.2
Ruby, J.G.3
Guo, H.4
Bartel, D.P.5
Lai, E.C.6
-
22
-
-
44449096738
-
Endogenous siRNAs derived from transposons and mRNAs in Drosophila somatic cells
-
Ghildiyal, M., H. Seitz, M.D. Horwich, C. Li, T. Du, S. Lee, J. Xu, E.L. Kittler, M.L. Zapp, Z. Weng, and P.D. Zamore. 2008. Endogenous siRNAs derived from transposons and mRNAs in Drosophila somatic cells. Science. 320:1077-1081.
-
(2008)
Science
, vol.320
, pp. 1077-1081
-
-
Ghildiyal, M.1
Seitz, H.2
Horwich, M.D.3
Li, C.4
Du, T.5
Lee, S.6
Xu, J.7
Kittler, E.L.8
Zapp, M.L.9
Weng, Z.10
Zamore, P.D.11
-
23
-
-
44349159416
-
Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes
-
Tam, O.H., A.A. Aravin, P. Stein, A. Girard, E.P. Murchison, S. Cheloufi, E. Hodges, M. Anger, R. Sachidanandam, R.M. Schultz, and G.J. Hannon. 2008. Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes. Nature. 453:534-538.
-
(2008)
Nature
, vol.453
, pp. 534-538
-
-
Tam, O.H.1
Aravin, A.A.2
Stein, P.3
Girard, A.4
Murchison, E.P.5
Cheloufi, S.6
Hodges, E.7
Anger, M.8
Sachidanandam, R.9
Schultz, R.M.10
Hannon, G.J.11
-
24
-
-
44349130233
-
Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes
-
Watanabe, T., Y. Totoki, A. Toyoda, M. Kaneda, S. Kuramochi-Miyagawa, Y. Obata, H. Chiba, Y. Kohara, T. Kono, T. Nakano, et al. 2008. Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes. Nature. 453:539-543.
-
(2008)
Nature
, vol.453
, pp. 539-543
-
-
Watanabe, T.1
Totoki, Y.2
Toyoda, A.3
Kaneda, M.4
Kuramochi-Miyagawa, S.5
Obata, Y.6
Chiba, H.7
Kohara, Y.8
Kono, T.9
Nakano, T.10
-
25
-
-
41549159660
-
IL-10 produced by regulatory T cells contributes to their suppressor function by limiting inflammation at environmental interfaces
-
Rubtsov, Y.P., J.P. Rasmussen, E.Y. Chi, J. Fontenot, L. Castell, X. Ye, P. Treuting, L. Siewe, A. Roers, W.R.J. Henderson, et al. 2008. IL-10 produced by regulatory T cells contributes to their suppressor function by limiting inflammation at environmental interfaces. Immunity. 28:546-558.
-
(2008)
Immunity
, vol.28
, pp. 546-558
-
-
Rubtsov, Y.P.1
Rasmussen, J.P.2
Chi, E.Y.3
Fontenot, J.4
Castell, L.5
Ye, X.6
Treuting, P.7
Siewe, L.8
Roers, A.9
Henderson, W.R.J.10
-
26
-
-
34548047719
-
Role of CD28 in fatal autoimmune disorder in scurfy mice
-
Singh, N., P.R. Chandler, Y. Seki, B. Baban, M. Takezaki, D.J. Kahler, D.H. Munn, C.P. Larsen, A.L. Mellor, and M. Iwashima. 2007. Role of CD28 in fatal autoimmune disorder in scurfy mice. Blood. 110:1199-1206.
-
(2007)
Blood
, vol.110
, pp. 1199-1206
-
-
Singh, N.1
Chandler, P.R.2
Seki, Y.3
Baban, B.4
Takezaki, M.5
Kahler, D.J.6
Munn, D.H.7
Larsen, C.P.8
Mellor, A.L.9
Iwashima, M.10
-
27
-
-
0036346861
-
Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome
-
Wildin, R.S., S. Smyk-Pearson, and A.H. Filipovich. 2002. Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome. J. Med. Genet. 39:537-545.
-
(2002)
J. Med. Genet
, vol.39
, pp. 537-545
-
-
Wildin, R.S.1
Smyk-Pearson, S.2
Filipovich, A.H.3
-
28
-
-
25444497719
-
Cutting edge: Direct suppression of B cells by CD4+ CD25+ regulatory T cells
-
Lim, H.W., P. Hillsamer, A.H. Banham, and C.H. Kim. 2005. Cutting edge: direct suppression of B cells by CD4+ CD25+ regulatory T cells. J. Immunol. 175:4180-4183.
-
(2005)
J. Immunol
, vol.175
, pp. 4180-4183
-
-
Lim, H.W.1
Hillsamer, P.2
Banham, A.H.3
Kim, C.H.4
-
29
-
-
33750832563
-
T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5′ - adenosine monophosphate to adenosine
-
Kobie, J.J., P.R. Shah, L. Yang, J.A. Rebhahn, D.J. Fowell, and T.R. Mosmann. 2006. T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5′ - adenosine monophosphate to adenosine. J. Immunol. 177:6780-6786.
-
(2006)
J. Immunol
, vol.177
, pp. 6780-6786
-
-
Kobie, J.J.1
Shah, P.R.2
Yang, L.3
Rebhahn, J.A.4
Fowell, D.J.5
Mosmann, T.R.6
-
30
-
-
3142708571
-
Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease
-
Paust, S., L. Lu, N. McCarty, and H. Cantor. 2004. Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease. Proc. Natl. Acad. Sci. USA. 101:10398-10403.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 10398-10403
-
-
Paust, S.1
Lu, L.2
McCarty, N.3
Cantor, H.4
-
31
-
-
39749101294
-
Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage
-
Koralov, S.B., S.A. Muljo, G.R. Galler, A. Krek, T. Chakraborty, C. Kanellopoulou, K. Jensen, B.S. Cobb, M. Merkenschlager, N. Rajewsky, and K. Rajewsky. 2008. Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage. Cell. 132:860-874.
-
(2008)
Cell
, vol.132
, pp. 860-874
-
-
Koralov, S.B.1
Muljo, S.A.2
Galler, G.R.3
Krek, A.4
Chakraborty, T.5
Kanellopoulou, C.6
Jensen, K.7
Cobb, B.S.8
Merkenschlager, M.9
Rajewsky, N.10
Rajewsky, K.11
-
32
-
-
36549030784
-
The inhibitory cytokine IL-35 contributes to regulatory T-cell function
-
Collison, L.W., C.J. Workman, T.T. Kuo, K. Boyd, Y. Wang, K.M. Vignali, R. Cross, D. Sehy, R.S. Blumberg, and D.A. Vignali. 2007. The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature. 450:566-569.
-
(2007)
Nature
, vol.450
, pp. 566-569
-
-
Collison, L.W.1
Workman, C.J.2
Kuo, T.T.3
Boyd, K.4
Wang, Y.5
Vignali, K.M.6
Cross, R.7
Sehy, D.8
Blumberg, R.S.9
Vignali, D.A.10
-
33
-
-
5844299536
-
Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development
-
Wolfer, A., T. Bakker, A. Wilson, M. Nicolas, V. Ioannidis, D.R. Littman, P.P. Lee, C.B. Wilson, W. Held, H.R. MacDonald, and F. Radtke. 2001. Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development. Nat. Immunol. 2:235-241.
-
(2001)
Nat. Immunol
, vol.2
, pp. 235-241
-
-
Wolfer, A.1
Bakker, T.2
Wilson, A.3
Nicolas, M.4
Ioannidis, V.5
Littman, D.R.6
Lee, P.P.7
Wilson, C.B.8
Held, W.9
MacDonald, H.R.10
Radtke, F.11
-
34
-
-
33644619021
-
Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs
-
Yi, R., D. O'Carroll, H.A. Pasolli, Z. Zhang, F.S. Dietrich, A. Tarakhovsky, and E. Fuchs. 2006. Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs. Nat. Genet. 38:356-362.
-
(2006)
Nat. Genet
, vol.38
, pp. 356-362
-
-
Yi, R.1
O'Carroll, D.2
Pasolli, H.A.3
Zhang, Z.4
Dietrich, F.S.5
Tarakhovsky, A.6
Fuchs, E.7
|