Rapid analysis of antibody self-association in complex mixtures using immunogold conjugates

Molecular Pharmaceutics

Volumn 10, Issue 4, 2013, Pages 1322-1331

  Sule, Shantanu V ^a   Dickinson, Craig D ^b   Lu, Jirong ^b   Chow, Chi Kin ^b   Tessier, Peter M ^a  

^a RENSSELAER POLYTECHNIC INSTITUTE   (United States)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

aggregation; high throughput; monoclonal antibody; nanoparticle; solubility; viscosity

Indexed keywords

ANTIBODY CONJUGATE; GOLD NANOPARTICLE; MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY;

AFFINITY CAPTURE SELF INTERACTION NANOPARTICLE SPECTROSCOPY; ARTICLE; CONJUGATE; CONTROLLED STUDY; CULTURE MEDIUM; HUMAN; IMMUNOGOLD LABELING; LIGHT SCATTERING; PRIORITY JOURNAL; PROPENSITY SCORE; PROTEIN ASSEMBLY; SPECTROSCOPY;

ADSORPTION; ANTIBODIES, MONOCLONAL; CHEMISTRY, PHARMACEUTICAL; CULTURE MEDIA; DIFFUSION; DRUG DESIGN; HUMANS; IMMUNOHISTOCHEMISTRY; KINETICS; LIGHT; NANOPARTICLES; NANOTECHNOLOGY; SCATTERING, RADIATION; SOLUBILITY; VISCOSITY;

EID: 84875763312     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp300524x     Document Type: Article

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