7,8-Dihydroxyflavone leads to survival of cultured embryonic motoneurons by activating intracellular signaling pathways

Molecular and Cellular Neuroscience

Volumn 56, Issue , 2013, Pages 18-28

  Tsai, Teresa ^a   Klausmeyer, Alice ^a   Conrad, Rebecca ^a   Gottschling, Christine ^a   Leo, Markus ^a   Faissner, Andreas ^a   Wiese, Stefan ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Agonist; BDNF; Flavonoids; Neurotrophin; Spinal cord; TrkB receptor

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 7,8 DIHYDROXYFLAVONE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; RECEPTOR; TROPOMYOSIN; TROPOMYOSIN RECEPTOR KINASE B RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; EMBRYO; HIPPOCAMPUS; INTRACELLULAR SIGNALING; MOTONEURON; MOUSE; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; WESTERN BLOTTING;

7,8-DHF; 7,8-DIHYDROXYFLAVONE; AGONIST; ALS; AMYOTROPHIC LATERAL SCLEROSIS; BDNF; BRAIN DERIVED NEUROTROPHIC FACTOR; E; EMBRYONIC DAY; FLAVONOIDS; KREBS-RINGER SOLUTION; KRH; MN; MOTONEURONS; NEUROTROPHIN; P75 NEUROTROPHIN RECEPTOR; P75(NTR); PARAFORMALDEHYDE; PBS; PFA; PHOSPHATE-BUFFERED SALINE; SMA; SPINAL CORD; SPINAL MUSCULAR ATROPHY; TBS; TRIS-BUFFERED SALINE; TRKB; TRKB RECEPTOR; TROPOMYOSIN-RELATED KINASE RECEPTOR TYROSINE KINASE B;

ANIMALS; CELL GROWTH PROCESSES; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVONES; HIPPOCAMPUS; MAP KINASE SIGNALING SYSTEM; MICE; MOTOR NEURONS; NEURITES; NEUROPROTECTIVE AGENTS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, TRKB; SPINAL CORD;

EID: 84875647455     PISSN: 10447431     EISSN: 10959327     Source Type: Journal    
DOI: 10.1016/j.mcn.2013.02.007     Document Type: Article

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