메뉴 건너뛰기




Volumn 32, Issue 6, 2013, Pages 858-873

FOXA1 mediates p16 INK4a activation during cellular senescence

Author keywords

FOXA1; p16INK4a; polycomb complex; senescence

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; HEPATOCYTE NUCLEAR FACTOR 3ALPHA;

EID: 84875453097     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2013.35     Document Type: Article
Times cited : (40)

References (86)
  • 1
    • 66249109644 scopus 로고    scopus 로고
    • Polycomb mediated epigenetic silencing and replication timing at the INK4a/ARF locus during senescence
    • Agherbi H, Gaussmann-Wenger A, Verthuy C, Chasson L, Serrano M, Djabali M (2009) Polycomb mediated epigenetic silencing and replication timing at the INK4a/ARF locus during senescence. PLoS ONE 4: e5622
    • (2009) PLoS ONE , vol.4
    • Agherbi, H.1    Gaussmann-Wenger, A.2    Verthuy, C.3    Chasson, L.4    Serrano, M.5    Djabali, M.6
  • 2
    • 0034933793 scopus 로고    scopus 로고
    • Id1 regulation of cellular senescence through transcriptional repression of p16/Ink4a
    • Alani RM, Young AZ, Shifflett CB (2001) Id1 regulation of cellular senescence through transcriptional repression of p16/Ink4a. Proc Natl Acad Sci USA 98: 7812-7816
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 7812-7816
    • Alani, R.M.1    Young, A.Z.2    Shifflett, C.B.3
  • 3
    • 0030477686 scopus 로고    scopus 로고
    • Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts
    • Alcorta DA, Xiong Y, Phelps D, Hannon G, Beach D, Barrett JC (1996) Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts. Proc Natl Acad Sci USA 93: 13742-13747
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 13742-13747
    • Alcorta, D.A.1    Xiong, Y.2    Phelps, D.3    Hannon, G.4    Beach, D.5    Barrett, J.C.6
  • 4
    • 80053611688 scopus 로고    scopus 로고
    • FOXA1: Master of steroid receptor function in cancer
    • Augello MA, Hickey TE, Knudsen KE (2011) FOXA1: master of steroid receptor function in cancer. EMBO J 30: 3885-3894
    • (2011) EMBO J , vol.30 , pp. 3885-3894
    • Augello, M.A.1    Hickey, T.E.2    Knudsen, K.E.3
  • 6
    • 77951878056 scopus 로고    scopus 로고
    • Induced pluripotent stem cells and senescence: Learning the biology to improve the technology
    • Banito A, Gil J (2010) Induced pluripotent stem cells and senescence: learning the biology to improve the technology. EMBO Rep 11: 353-359
    • (2010) EMBO Rep , vol.11 , pp. 353-359
    • Banito, A.1    Gil, J.2
  • 8
    • 84860335505 scopus 로고    scopus 로고
    • Association between type 2 diabetes and CDKN2A/B: A meta-analysis study
    • Bao XY, Xie C, Yang MS (2012) Association between type 2 diabetes and CDKN2A/B: a meta-analysis study. Mol Biol Rep 39: 1609-1616
    • (2012) Mol Biol Rep , vol.39 , pp. 1609-1616
    • Bao, X.Y.1    Xie, C.2    Yang, M.S.3
  • 10
    • 84864041695 scopus 로고    scopus 로고
    • Genome-wide location analysis reveals distinct transcriptional circuitry by paralogous regulators Foxa1 and Foxa2
    • Bochkis IM, Schug J, Ye DZ, Kurinna S, Stratton SA, Barton MC, Kaestner KH (2012) Genome-wide location analysis reveals distinct transcriptional circuitry by paralogous regulators Foxa1 and Foxa2. PLoS Genet 8: e1002770
    • (2012) PLoS Genet , vol.8
    • Bochkis, I.M.1    Schug, J.2    Ye, D.Z.3    Kurinna, S.4    Stratton, S.A.5    Barton, M.C.6    Kaestner, K.H.7
  • 11
    • 33646870495 scopus 로고    scopus 로고
    • Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions
    • Bracken AP, Dietrich N, Pasini D, Hansen KH, Helin K (2006) Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions. Genes Dev 20: 1123-1136
    • (2006) Genes Dev , vol.20 , pp. 1123-1136
    • Bracken, A.P.1    Dietrich, N.2    Pasini, D.3    Hansen, K.H.4    Helin, K.5
  • 13
  • 14
    • 0030964277 scopus 로고    scopus 로고
    • The biology of replicative senescence
    • Campisi J (1997) The biology of replicative senescence. Eur J Cancer 33: 703-709
    • (1997) Eur J Cancer , vol.33 , pp. 703-709
    • Campisi, J.1
  • 15
    • 0035500487 scopus 로고    scopus 로고
    • Cellular senescence as a tumor-suppressor mechanism
    • Campisi J (2001a) Cellular senescence as a tumor-suppressor mechanism. Trends Cell Biol 11: S27-S31
    • (2001) Trends Cell Biol , vol.11
    • Campisi, J.1
  • 16
    • 0035059672 scopus 로고    scopus 로고
    • From cells to organisms: Can we learn about aging from cells in culture?
    • Campisi J (2001b) From cells to organisms: can we learn about aging from cells in culture? Exp Gerontol 36: 607-618
    • (2001) Exp Gerontol , vol.36 , pp. 607-618
    • Campisi, J.1
  • 17
    • 13944270339 scopus 로고    scopus 로고
    • Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors
    • Campisi J (2005) Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 120: 513-522
    • (2005) Cell , vol.120 , pp. 513-522
    • Campisi, J.1
  • 18
    • 0036387193 scopus 로고    scopus 로고
    • Forkhead transcription factors: Key players in development and metabolism
    • Carlsson P, Mahlapuu M (2002) Forkhead transcription factors: key players in development and metabolism. Dev Biol 250: 1-23
    • (2002) Dev Biol , vol.250 , pp. 1-23
    • Carlsson, P.1    Mahlapuu, M.2
  • 21
    • 0036184236 scopus 로고    scopus 로고
    • Opening of compacted chromatin by early developmental transcription factors HNF3 (FoxA) and GATA-4
    • Cirillo LA, Lin FR, Cuesta I, Friedman D, Jarnik M, Zaret KS (2002) Opening of compacted chromatin by early developmental transcription factors HNF3 (FoxA) and GATA-4. Mol Cell 9: 279-289
    • (2002) Mol Cell , vol.9 , pp. 279-289
    • Cirillo, L.A.1    Lin, F.R.2    Cuesta, I.3    Friedman, D.4    Jarnik, M.5    Zaret, K.S.6
  • 23
    • 0033388099 scopus 로고    scopus 로고
    • An early developmental transcription factor complex that is more stable on nucleosome core particles than on free DNA
    • Cirillo LA, Zaret KS (1999) An early developmental transcription factor complex that is more stable on nucleosome core particles than on free DNA. Mol Cell 4: 961-969
    • (1999) Mol Cell , vol.4 , pp. 961-969
    • Cirillo, L.A.1    Zaret, K.S.2
  • 24
    • 33846589909 scopus 로고    scopus 로고
    • Specific interactions of the wing domains of FOXA1 transcription factor with DNA
    • Cirillo LA, Zaret KS (2007) Specific interactions of the wing domains of FOXA1 transcription factor with DNA. J Mol Biol 366: 720-724
    • (2007) J Mol Biol , vol.366 , pp. 720-724
    • Cirillo, L.A.1    Zaret, K.S.2
  • 25
    • 0027270989 scopus 로고
    • Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5
    • Clark KL, Halay ED, Lai E, Burley SK (1993) Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5. Nature 364: 412-420
    • (1993) Nature , vol.364 , pp. 412-420
    • Clark, K.L.1    Halay, E.D.2    Lai, E.3    Burley, S.K.4
  • 30
    • 29144435153 scopus 로고    scopus 로고
    • Footprinting of mammalian promoters: Use of a CpG DNA methyltransferase revealing nucleosome positions at a single molecule level
    • Fatemi M, Pao MM, Jeong S, Gal-Yam EN, Egger G, Weisenberger DJ, Jones PA (2005) Footprinting of mammalian promoters: use of a CpG DNA methyltransferase revealing nucleosome positions at a single molecule level. Nucleic Acids Res 33: e176
    • (2005) Nucleic Acids Res , vol.33
    • Fatemi, M.1    Pao, M.M.2    Jeong, S.3    Gal-Yam, E.N.4    Egger, G.5    Weisenberger, D.J.6    Jones, P.A.7
  • 33
    • 58049204234 scopus 로고    scopus 로고
    • Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development
    • Gao N, LeLay J, Vatamaniuk MZ, Rieck S, Friedman JR, Kaestner KH (2008) Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development. Genes Dev 22: 3435-3448
    • (2008) Genes Dev , vol.22 , pp. 3435-3448
    • Gao, N.1    Lelay, J.2    Vatamaniuk, M.Z.3    Rieck, S.4    Friedman, J.R.5    Kaestner, K.H.6
  • 34
    • 33747587608 scopus 로고    scopus 로고
    • Regulation of the INK4b-ARF-INK4a tumour suppressor locus: All for one or one for all
    • Gil J, Peters G (2006) Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all. Nat Rev Mol Cell Biol 7: 667-677
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 667-677
    • Gil, J.1    Peters, G.2
  • 36
    • 33644871338 scopus 로고    scopus 로고
    • Reduced c-Myc signaling triggers telomere-independent senescence by regulating Bmi-1 and p16(INK4a)
    • Guney I, Wu S, Sedivy JM (2006) Reduced c-Myc signaling triggers telomere-independent senescence by regulating Bmi-1 and p16(INK4a). Proc Natl Acad Sci USA 103: 3645-3650
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 3645-3650
    • Guney, I.1    Wu, S.2    Sedivy, J.M.3
  • 37
    • 0344926374 scopus 로고    scopus 로고
    • The basic helix-loop-helix transcription factor TAL1/SCL inhibits the expression of the p16INK4A and pTalpha genes
    • Hansson A, Manetopoulos C, Jonsson JI, Axelson H (2003) The basic helix-loop-helix transcription factor TAL1/SCL inhibits the expression of the p16INK4A and pTalpha genes. Biochem Biophys Res Commun 312: 1073-1081
    • (2003) Biochem Biophys Res Commun , vol.312 , pp. 1073-1081
    • Hansson, A.1    Manetopoulos, C.2    Jonsson, J.I.3    Axelson, H.4
  • 38
    • 50549218525 scopus 로고
    • The limited in vitro lifetime of human diploid cell strains
    • Hayflick L (1965) The limited in vitro lifetime of human diploid cell strains. Exp Cell Res 37: 614-636
    • (1965) Exp Cell Res , vol.37 , pp. 614-636
    • Hayflick, L.1
  • 39
    • 0344622606 scopus 로고
    • The serial cultivation of human diploid cell strains
    • Hayflick L, Moorhead PS (1961) The serial cultivation of human diploid cell strains. Exp Cell Res 25: 585-621
    • (1961) Exp Cell Res , vol.25 , pp. 585-621
    • Hayflick, L.1    Moorhead, P.S.2
  • 41
    • 68049104358 scopus 로고    scopus 로고
    • Aberrant de novo methylation of the p16INK4A CpG island is initiated post gene silencing in association with chromatin remodelling and mimics nucleosome positioning
    • Hinshelwood RA, Melki JR, Huschtscha LI, Paul C, Song JZ, Stirzaker C, Reddel RR, Clark SJ (2009) Aberrant de novo methylation of the p16INK4A CpG island is initiated post gene silencing in association with chromatin remodelling and mimics nucleosome positioning. Human Mol Genet 18: 3098-3109
    • (2009) Human Mol Genet , vol.18 , pp. 3098-3109
    • Hinshelwood, R.A.1    Melki, J.R.2    Huschtscha, L.I.3    Paul, C.4    Song, J.Z.5    Stirzaker, C.6    Reddel, R.R.7    Clark, S.J.8
  • 42
    • 0032128183 scopus 로고    scopus 로고
    • Pha-4, an HNF-3 homolog, specifies pharyngeal organ identity in Caenorhabditis elegans
    • Horner MA, Quintin S, Domeier ME, Kimble J, Labouesse M, Mango SE (1998) pha-4, an HNF-3 homolog, specifies pharyngeal organ identity in Caenorhabditis elegans. Genes Dev 12: 1947-1952
    • (1998) Genes Dev , vol.12 , pp. 1947-1952
    • Horner, M.A.1    Quintin, S.2    Domeier, M.E.3    Kimble, J.4    Labouesse, M.5    Mango, S.E.6
  • 43
  • 47
    • 0033557490 scopus 로고    scopus 로고
    • Inactivation of the winged helix transcription factor HNF3alpha affects glucose homeostasis and islet glucagon gene expression in vivo
    • Kaestner KH, Katz J, Liu Y, Drucker DJ, Schutz G (1999) Inactivation of the winged helix transcription factor HNF3alpha affects glucose homeostasis and islet glucagon gene expression in vivo. Genes Dev 13: 495-504
    • (1999) Genes Dev , vol.13 , pp. 495-504
    • Kaestner, K.H.1    Katz, J.2    Liu, Y.3    Drucker, D.J.4    Schutz, G.5
  • 48
    • 0031818323 scopus 로고    scopus 로고
    • Pha-4 is Ce-fkh-1, a fork head/HNF-3alpha,beta,gamma homolog that functions in organogenesis of the C elegans pharynx
    • Kalb JM, Lau KK, Goszczynski B, Fukushige T, Moons D, Okkema PG, McGhee JD (1998) pha-4 is Ce-fkh-1, a fork head/HNF-3alpha,beta,gamma homolog that functions in organogenesis of the C. elegans pharynx. Development 125: 2171-2180
    • (1998) Development , vol.125 , pp. 2171-2180
    • Kalb, J.M.1    Lau, K.K.2    Goszczynski, B.3    Fukushige, T.4    Moons, D.5    Okkema, P.G.6    McGhee, J.D.7
  • 49
    • 16644382513 scopus 로고    scopus 로고
    • Human FOX gene family (Review)
    • Katoh M (2004) Human FOX gene family (Review). Int J Oncol 25: 1495-1500
    • (2004) Int J Oncol , vol.25 , pp. 1495-1500
    • Katoh, M.1
  • 52
    • 20544473735 scopus 로고    scopus 로고
    • The initiation of liver development is dependent on Foxa transcription factors
    • Lee CS, Friedman JR, Fulmer JT, Kaestner KH (2005) The initiation of liver development is dependent on Foxa transcription factors. Nature 435: 944-947
    • (2005) Nature , vol.435 , pp. 944-947
    • Lee, C.S.1    Friedman, J.R.2    Fulmer, J.T.3    Kaestner, K.H.4
  • 56
    • 0027507894 scopus 로고
    • An active tissue-specific enhancer and bound transcription factors existing in a precisely positioned nucleosomal array
    • McPherson CE, Shim EY, Friedman DS, Zaret KS (1993) An active tissue-specific enhancer and bound transcription factors existing in a precisely positioned nucleosomal array. Cell 75: 387-398
    • (1993) Cell , vol.75 , pp. 387-398
    • McPherson, C.E.1    Shim, E.Y.2    Friedman, D.S.3    Zaret, K.S.4
  • 59
    • 0037667702 scopus 로고    scopus 로고
    • Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence
    • Narita M, Nunez S, Heard E, Lin AW, Hearn SA, Spector DL, Hannon GJ, Lowe SW(2003) Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell 113: 703-716
    • (2003) Cell , vol.113 , pp. 703-716
    • Narita, M.1    Nunez, S.2    Heard, E.3    Lin, A.W.4    Hearn, S.A.5    Spector, D.L.6    Hannon, G.J.7    Lowe, S.W.8
  • 61
    • 34249888736 scopus 로고    scopus 로고
    • PHA-4/Foxa mediates diet-restriction-induced longevity of C elegans
    • Panowski SH, Wolff S, Aguilaniu H, Durieux J, Dillin A (2007) PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans. Nature 447: 550-555
    • (2007) Nature , vol.447 , pp. 550-555
    • Panowski, S.H.1    Wolff, S.2    Aguilaniu, H.3    Durieux, J.4    Dillin, A.5
  • 62
    • 0034660640 scopus 로고    scopus 로고
    • JunB suppresses cell proliferation by transcriptional activation of p16(INK4a) expression
    • Passegue E, Wagner EF (2000) JunB suppresses cell proliferation by transcriptional activation of p16(INK4a) expression. EMBO J 19: 2969-2979
    • (2000) EMBO J , vol.19 , pp. 2969-2979
    • Passegue, E.1    Wagner, E.F.2
  • 63
    • 46149108345 scopus 로고    scopus 로고
    • Rapid, transcription-independent loss of nucleosomes over a large chromatin domain at Hsp70 loci
    • Petesch SJ, Lis JT (2008) Rapid, transcription-independent loss of nucleosomes over a large chromatin domain at Hsp70 loci. Cell 134: 74-84
    • (2008) Cell , vol.134 , pp. 74-84
    • Petesch, S.J.1    Lis, J.T.2
  • 64
    • 0000299214 scopus 로고
    • Evidence for a relationship between longevity of mammalian species and life spans of normal fibroblasts in vitro and erythrocytes in vivo
    • Rohme D (1981) Evidence for a relationship between longevity of mammalian species and life spans of normal fibroblasts in vitro and erythrocytes in vivo. Proc Natl Acad Sci USA 78: 5009-5013
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 5009-5013
    • Rohme, D.1
  • 66
    • 20444403749 scopus 로고    scopus 로고
    • Intrinsic histone-DNA interactions and low nucleosome density are important for preferential accessibility of promoter regions in yeast
    • Sekinger EA, Moqtaderi Z, Struhl K (2005) Intrinsic histone-DNA interactions and low nucleosome density are important for preferential accessibility of promoter regions in yeast. Mol Cell 18: 735-748
    • (2005) Mol Cell , vol.18 , pp. 735-748
    • Sekinger, E.A.1    Moqtaderi, Z.2    Struhl, K.3
  • 68
    • 0027769876 scopus 로고
    • A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano M, Hannon GJ, Beach D (1993) A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature 366: 704-707
    • (1993) Nature , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 69
    • 0030944985 scopus 로고    scopus 로고
    • Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
    • Serrano M, Lin AW, McCurrach ME, Beach D, Lowe SW (1997) Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 88: 593-602
    • (1997) Cell , vol.88 , pp. 593-602
    • Serrano, M.1    Lin, A.W.2    McCurrach, M.E.3    Beach, D.4    Lowe, S.W.5
  • 70
    • 0033621155 scopus 로고    scopus 로고
    • Impaired glucose homeostasis and neonatal mortality in hepatocyte nuclear factor 3alpha-deficient mice
    • Shih DQ, Navas MA, Kuwajima S, Duncan SA, Stoffel M (1999) Impaired glucose homeostasis and neonatal mortality in hepatocyte nuclear factor 3alpha-deficient mice. Proc Natl Acad Sci USA 96: 10152-10157
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 10152-10157
    • Shih, D.Q.1    Navas, M.A.2    Kuwajima, S.3    Duncan, S.A.4    Stoffel, M.5
  • 71
    • 0037102234 scopus 로고    scopus 로고
    • Different telomere damage signaling pathways in human and mouse cells
    • Smogorzewska A, de Lange T (2002) Different telomere damage signaling pathways in human and mouse cells. EMBO J 21: 4338-4348
    • (2002) EMBO J , vol.21 , pp. 4338-4348
    • Smogorzewska, A.1    De Lange, T.2
  • 72
    • 0037439686 scopus 로고    scopus 로고
    • Inducible activation of Ras and Raf in adult epidermis
    • Tarutani M, Cai T, Dajee M, Khavari PA (2003) Inducible activation of Ras and Raf in adult epidermis. Cancer Res 63: 319-323
    • (2003) Cancer Res , vol.63 , pp. 319-323
    • Tarutani, M.1    Cai, T.2    Dajee, M.3    Khavari, P.A.4
  • 73
    • 0036923833 scopus 로고    scopus 로고
    • Looping and interaction between hypersensitive sites in the active beta-globin locus
    • Tolhuis B, Palstra RJ, Splinter E, Grosveld F, de Laat W (2002) Looping and interaction between hypersensitive sites in the active beta-globin locus. Mol Cell 10: 1453-1465
    • (2002) Mol Cell , vol.10 , pp. 1453-1465
    • Tolhuis, B.1    Palstra, R.J.2    Splinter, E.3    Grosveld, F.4    De Laat, W.5
  • 74
    • 38849168162 scopus 로고    scopus 로고
    • Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7
    • Wajapeyee N, Serra RW, Zhu X, Mahalingam M, Green MR (2008) Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7. Cell 132: 363-374
    • (2008) Cell , vol.132 , pp. 363-374
    • Wajapeyee, N.1    Serra, R.W.2    Zhu, X.3    Mahalingam, M.4    Green, M.R.5
  • 78
    • 33645297174 scopus 로고    scopus 로고
    • Hematopoietic stem cell senescence and long-term bone marrow injury
    • Wang Y, Schulte BA, Zhou D (2006) Hematopoietic stem cell senescence and long-term bone marrow injury. Cell Cycle 5: 35-38
    • (2006) Cell Cycle , vol.5 , pp. 35-38
    • Wang, Y.1    Schulte, B.A.2    Zhou, D.3
  • 79
    • 77949346987 scopus 로고    scopus 로고
    • Investigation of type 2 diabetes risk alleles support CDKN2A/B, CDKAL1, and TCF7L2 as susceptibility genes in a Han Chinese cohort
    • Wen J, Ronn T, Olsson A, Yang Z, Lu B, Du Y, Groop L, Ling C, Hu R (2010) Investigation of type 2 diabetes risk alleles support CDKN2A/B, CDKAL1, and TCF7L2 as susceptibility genes in a Han Chinese cohort. PLoS ONE 5: e9153
    • (2010) PLoS ONE , vol.5
    • Wen, J.1    Ronn, T.2    Olsson, A.3    Yang, Z.4    Lu, B.5    Du, Y.6    Groop, L.7    Ling, C.8    Hu, R.9
  • 83
    • 0033135570 scopus 로고    scopus 로고
    • Developmental competence of the gut endoderm: Genetic potentiation by GATA and HNF3/fork head proteins
    • Zaret K (1999) Developmental competence of the gut endoderm: genetic potentiation by GATA and HNF3/fork head proteins. Dev Biol 209: 1-10
    • (1999) Dev Biol , vol.209 , pp. 1-10
    • Zaret, K.1
  • 84
    • 80455144479 scopus 로고    scopus 로고
    • Pioneer transcription factors: Establishing competence for gene expression
    • Zaret KS, Carroll JS (2011) Pioneer transcription factors: establishing competence for gene expression. Genes Dev 25: 2227-2241
    • (2011) Genes Dev , vol.25 , pp. 2227-2241
    • Zaret, K.S.1    Carroll, J.S.2
  • 85
    • 77956504687 scopus 로고    scopus 로고
    • CCCTC-binding factor acts upstream of FOXA1 and demarcates the genomic response to estrogen
    • Zhang Y, Liang J, Li Y, Xuan C, Wang F, Wang D, Shi L, Zhang D, Shang Y (2010) CCCTC-binding factor acts upstream of FOXA1 and demarcates the genomic response to estrogen. J Biol Chem 285: 28604-28613
    • (2010) J Biol Chem , vol.285 , pp. 28604-28613
    • Zhang, Y.1    Liang, J.2    Li, Y.3    Xuan, C.4    Wang, F.5    Wang, D.6    Shi, L.7    Zhang, D.8    Shang, Y.9
  • 86
    • 3843115623 scopus 로고    scopus 로고
    • Regulation of cellular senescence and p16(INK4a) expression by Id1 and E47 proteins in human diploid fibroblast
    • Zheng W, Wang H, Xue L, Zhang Z, Tong T (2004) Regulation of cellular senescence and p16(INK4a) expression by Id1 and E47 proteins in human diploid fibroblast. J Biol Chem 279: 31524-31532
    • (2004) J Biol Chem , vol.279 , pp. 31524-31532
    • Zheng, W.1    Wang, H.2    Xue, L.3    Zhang, Z.4    Tong, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.